Sadaf Shadan
@sshadan.bsky.social
Senior Editor @Nature handling manuscripts in general cell biology and plant biology. Views expressed here are my own.
Lipid transfer proteins (LTPs) maintain the specific lipid compositions of cellular membranes. @nature, a systematic characterization of complexes between human LTPs and their lipid cargo provides a resource for a better understanding of these proteins.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Client Challenge
www.nature.com
January 13, 2026 at 7:10 PM
Lipid transfer proteins (LTPs) maintain the specific lipid compositions of cellular membranes. @nature, a systematic characterization of complexes between human LTPs and their lipid cargo provides a resource for a better understanding of these proteins.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The journal Nature is looking for a Metabolism and Cardiovascular biology editor -- deadline coming soon.
springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com/SpringerNatu...
Associate or Senior Editor, Nature Biological, Clinical, and Social Sciences
Title: Associate or Senior Editor, Nature Biological, Clinical, and Social Sciences Organization: Nature Portfolio Locations: New York, Jersey City, or Berlin – Hybrid Working Model Closing Date: Janu...
springernature.wd3.myworkdayjobs.com
January 6, 2026 at 8:54 AM
The journal Nature is looking for a Metabolism and Cardiovascular biology editor -- deadline coming soon.
springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com/SpringerNatu...
Disruption of protein import into mitochondria affects cellular balance and can cause disease. Work @nature shows that cells sense this defect through inter-organelle communication and a signalling role of mitochondrial targeting sequence.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A direct role for a mitochondrial targeting sequence in signalling stress - Nature
Cells can sense mitochondrial damage through signalling via an unimported mitochondrial targeting sequence.
www.nature.com
December 10, 2025 at 4:29 PM
Disruption of protein import into mitochondria affects cellular balance and can cause disease. Work @nature shows that cells sense this defect through inter-organelle communication and a signalling role of mitochondrial targeting sequence.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
One environmental factor that affects crop yield is soil stress. Work @nature shows how soil compaction stress affects plant root growth through hormonal signals and cell-wall remodelling.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Ethylene modulates cell wall mechanics for root responses to compaction - Nature
Soil compaction traps ethylene around roots, which causes transcriptional upregulation of Auxin Response Factor1, resulting in decreased root cortical cell wall thickness and thereby promoting root ra...
www.nature.com
November 27, 2025 at 3:42 PM
One environmental factor that affects crop yield is soil stress. Work @nature shows how soil compaction stress affects plant root growth through hormonal signals and cell-wall remodelling.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
On plant cells, receptor-like kinases mediate both immune and symbiotic signalling. Work @nature provides amino-acid-level molecular insights into how signalling specificity is achieved downstream of such similar receptors.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Two residues reprogram immunity receptors for nitrogen-fixing symbiosis - Nature
An investigation of plant receptor-like kinases identifies regions of these proteins that control whether immune or symbiotic signalling pathways are activated, with minimal changes to specific r...
www.nature.com
November 10, 2025 at 4:29 PM
On plant cells, receptor-like kinases mediate both immune and symbiotic signalling. Work @nature provides amino-acid-level molecular insights into how signalling specificity is achieved downstream of such similar receptors.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The >1000 lipid species found in eukaryotic cells have vital functions. Using a combination of microscopy, spectroscopy and modelling, authors report @nature the first quantitative map of retrograde flux of individual lipids in cells.
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 8:43 AM
The >1000 lipid species found in eukaryotic cells have vital functions. Using a combination of microscopy, spectroscopy and modelling, authors report @nature the first quantitative map of retrograde flux of individual lipids in cells.
An @nature paper presents a single-cell multi-omics atlas of eight rice organs. Insights emerging from this resource include new cell states during rice development and correlations between cell type and agronomic traits.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A single-cell multi-omics atlas of rice - Nature
A single-cell multi-omics atlas of rice is revealed, providing insight into cell-type functions and molecular programs.
www.nature.com
July 24, 2025 at 5:32 PM
An @nature paper presents a single-cell multi-omics atlas of eight rice organs. Insights emerging from this resource include new cell states during rice development and correlations between cell type and agronomic traits.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
In today’s issue of @nature, read a Review article on the latest and upcoming technologies that could aid research and development in crop science, contributing to sustainable global food security. www.nature.com/articles/s41...
Integrated biotechnological and AI innovations for crop improvement - Nature
The integration of omics technologies, genome editing and protein design with artificial intelligence (AI) promises rapid advances in the field of crop improvement that will improve global food securi...
www.nature.com
July 24, 2025 at 5:29 PM
In today’s issue of @nature, read a Review article on the latest and upcoming technologies that could aid research and development in crop science, contributing to sustainable global food security. www.nature.com/articles/s41...
Plant NLR receptors mediate pathogen resistance, and so their engineering could lead to crops with broader pathogen specificity and so broader disease resistance. @nature, authors report one such attempt achieving resistance to several potyviruses. www.nature.com/articles/s41...
& shorturl.at/932j7
& shorturl.at/932j7
Remodelling autoactive NLRs for broad-spectrum immunity in plants - Nature
Cleavage by pathogen-derived proteases of an engineered chimeric protein activates its plant immune receptor component, enabling broad-spectrum resistance to pathogens in plants.
www.nature.com
July 24, 2025 at 5:21 PM
Plant NLR receptors mediate pathogen resistance, and so their engineering could lead to crops with broader pathogen specificity and so broader disease resistance. @nature, authors report one such attempt achieving resistance to several potyviruses. www.nature.com/articles/s41...
& shorturl.at/932j7
& shorturl.at/932j7
How the plant defence hormone salicylic acid (SA) is formed in some bacteria and in Arabidopsis is well-established. Three @nature papers now describe a different pathway of SA biosynthesis in non-Brassicaceae plants.
rb.gy/9tgn8g
shorturl.at/fYAYo
shorturl.at/UCvo0
& NV
tinyurl.com/bdz2p6dx
rb.gy/9tgn8g
shorturl.at/fYAYo
shorturl.at/UCvo0
& NV
tinyurl.com/bdz2p6dx
Three-step biosynthesis of salicylic acid from benzoyl-CoA in plants - Nature
The salicylic acid (SA) biosynthesis pathway—involving ligation of benzoyl coenzyme A and benzyl alcohol to give benzyl benzoate; hydroxylation of benzyl benzoate to give benzyl salicylate; and cleava...
rb.gy
July 24, 2025 at 8:54 AM
How the plant defence hormone salicylic acid (SA) is formed in some bacteria and in Arabidopsis is well-established. Three @nature papers now describe a different pathway of SA biosynthesis in non-Brassicaceae plants.
rb.gy/9tgn8g
shorturl.at/fYAYo
shorturl.at/UCvo0
& NV
tinyurl.com/bdz2p6dx
rb.gy/9tgn8g
shorturl.at/fYAYo
shorturl.at/UCvo0
& NV
tinyurl.com/bdz2p6dx
Very much looking forward to hearing and seeing exciting research and to interacting with reseachers at #2025ISMPMI. Happy also to answer any questions about publishing in Nature and sister journals.
July 13, 2025 at 1:30 PM
Very much looking forward to hearing and seeing exciting research and to interacting with reseachers at #2025ISMPMI. Happy also to answer any questions about publishing in Nature and sister journals.
How do plants notice loss of structural barriers (e.g. the periderm, which prevents water loss and pathogen infection) to regenerate them? Work @nature shows that plants sense damage to barrier integrity from diffusion of gases such as ethylene and oxygen. shorturl.at/FIhJ8
& N&V
shorturl.at/u7PYs
& N&V
shorturl.at/u7PYs
Injured plants use gaseous cues to initiate repair of their outer layers
The periderm layers of plants form an outer protective barrier. If the periderm is broken, movement of the gases ethylene and oxygen triggers a healing process.
shorturl.at
July 2, 2025 at 3:14 PM
How do plants notice loss of structural barriers (e.g. the periderm, which prevents water loss and pathogen infection) to regenerate them? Work @nature shows that plants sense damage to barrier integrity from diffusion of gases such as ethylene and oxygen. shorturl.at/FIhJ8
& N&V
shorturl.at/u7PYs
& N&V
shorturl.at/u7PYs
A bottleneck for studying the biological function of biomolecular condensates is unavailability of tools to selectively probe them within living cells. @nature, researchers report one such tool, showcasing its use in various contexts including disease. www.nature.com/articles/s41...
Probing condensate microenvironments with a micropeptide killswitch - Nature
Targeting a non-natural micropeptide ‘killswitch’ to several biomolecular condensates altered condensate compositions and revealed condensate functions in human cells
www.nature.com
June 5, 2025 at 9:03 AM
A bottleneck for studying the biological function of biomolecular condensates is unavailability of tools to selectively probe them within living cells. @nature, researchers report one such tool, showcasing its use in various contexts including disease. www.nature.com/articles/s41...
The diverse cellular roles of early endosomes involve coordinated activity of several hundred integral membrane proteins and transiently associated regulatory complexes. A study @nature presents a systematic structural interactome of human endosomes . www.nature.com/articles/s41...
EndoMAP.v1 charts the structural landscape of human early endosome complexes - Nature
A study presents EndoMAP.v1, a resource that combines information on protein interactions and crosslink-supported structural predictions to map the interaction landscape of early endosomes.
www.nature.com
May 28, 2025 at 3:09 PM
The diverse cellular roles of early endosomes involve coordinated activity of several hundred integral membrane proteins and transiently associated regulatory complexes. A study @nature presents a systematic structural interactome of human endosomes . www.nature.com/articles/s41...
Want a taster of working as an editor? Nature has a locum position open for someone with interest in stem cell biology, developmental biology, and/or specific aspects of general cell biology. springernature.wd3.myworkdayjobs.com/SpringerNatu...
Locum Associate or Senior Editor, Nature (Biological, Clinical, and Social Sciences)
Job title: Locum Associate or Senior Editor, Nature (Biological, Clinical, and Social Sciences) Location: New York or Berlin (Hybrid working pattern) Deadline: June 11th , 2025 About Springer Nature G...
springernature.wd3.myworkdayjobs.com
May 28, 2025 at 8:06 AM
Want a taster of working as an editor? Nature has a locum position open for someone with interest in stem cell biology, developmental biology, and/or specific aspects of general cell biology. springernature.wd3.myworkdayjobs.com/SpringerNatu...
Legume can form symbiotic relationship with some bacteria, while recognising others as pathogens. Work @nature identifies a plant kinase that mediates this nuanced balance of tolerance towards symbionts without compromised plant immunity. www.nature.com/articles/s41...
A kinase mediator of rhizobial symbiosis and immunity in Medicago - Nature
Nature - A kinase mediator of rhizobial symbiosis and immunity in Medicago
www.nature.com
May 6, 2025 at 3:08 PM
Legume can form symbiotic relationship with some bacteria, while recognising others as pathogens. Work @nature identifies a plant kinase that mediates this nuanced balance of tolerance towards symbionts without compromised plant immunity. www.nature.com/articles/s41...
The E3 ubiquitin ligase complex SIFI has a role in terminating stress response signalling, to restore cellular homeostasis. Researchers @nature present the cryo-EM structure of this ~1.3 MDa complex providing insights into its mechanism of action. www.nature.com/articles/s41...
Molecular basis of SIFI activity in the integrated stress response - Nature
Nature - Molecular basis of SIFI activity in the integrated stress response
www.nature.com
May 6, 2025 at 3:05 PM
The E3 ubiquitin ligase complex SIFI has a role in terminating stress response signalling, to restore cellular homeostasis. Researchers @nature present the cryo-EM structure of this ~1.3 MDa complex providing insights into its mechanism of action. www.nature.com/articles/s41...
Plant roots adapt to their environment including to soil conditions. Using single-cell transcriptomics, @nature authors report on the rice root responses and adaptations to soil-related stresses at individual cell level. www.nature.com/articles/s41...
Single-cell transcriptomics reveal how root tissues adapt to soil stress - Nature
Single-cell RNA sequencing and spatial transcriptomic approaches reveal major expression changes in outer root cell types when grown in soil versus gel conditions, and also uncover how root tissu...
www.nature.com
April 30, 2025 at 4:16 PM
Plant roots adapt to their environment including to soil conditions. Using single-cell transcriptomics, @nature authors report on the rice root responses and adaptations to soil-related stresses at individual cell level. www.nature.com/articles/s41...
At membrane contact sites, bridge-like transport proteins, e.g. LPD-3, mediate bulk lipid transfer between cellular organelles. @nature see cryo-EM structure of native LDP-3, and gain insights into its functioning and interaction with other proteins and lipids.
shorturl.at/lycuz & shorturl.at/ARpUK
shorturl.at/lycuz & shorturl.at/ARpUK
Structural basis of lipid transfer by a bridge-like lipid-transfer protein - Nature
The LPD-3 complex structure reveals protein–lipid interactions that suggest a model for how the native LPD-3 complex mediates bulk lipid transport and provides a foundation for mechanistic studies of ...
shorturl.at
April 23, 2025 at 3:14 PM
At membrane contact sites, bridge-like transport proteins, e.g. LPD-3, mediate bulk lipid transfer between cellular organelles. @nature see cryo-EM structure of native LDP-3, and gain insights into its functioning and interaction with other proteins and lipids.
shorturl.at/lycuz & shorturl.at/ARpUK
shorturl.at/lycuz & shorturl.at/ARpUK
The technique of haploid induction creates homozygous plants, enabling faster breeding cycles. A paper @nature discovers a way of generating haploid sunflower, and optimises the approach for efficiency compatible with breeding programs for this important oilseed crop. rb.gy/vrqana & N&V rb.gy/e7uyep
Haploid facultative parthenogenesis in sunflower sexual reproduction - Nature
Spontaneous parthenogenesis in sunflower has been used to develop a scalable doubled haploid breeding system.
rb.gy
April 8, 2025 at 3:21 PM
The technique of haploid induction creates homozygous plants, enabling faster breeding cycles. A paper @nature discovers a way of generating haploid sunflower, and optimises the approach for efficiency compatible with breeding programs for this important oilseed crop. rb.gy/vrqana & N&V rb.gy/e7uyep
Proteins and nucleic acids move in and out of the nucleus through nuclear pore complexes (NPCs). Using 3D MINFLUX, @nature authors study single import and export events, gaining detailed insights into transport across NPCs within cells and at nanometer and millisecond scales.
shorturl.at/2ClQp
shorturl.at/2ClQp
Overlapping nuclear import and export paths unveiled by two-colour MINFLUX - Nature
High spatiotemporal precision tracking using 3D MINFLUX shows that nuclear import and export occur in overlapping regions of the central pore, providing insight into transport across the nuclear pore ...
www.nature.com
March 19, 2025 at 4:12 PM
Proteins and nucleic acids move in and out of the nucleus through nuclear pore complexes (NPCs). Using 3D MINFLUX, @nature authors study single import and export events, gaining detailed insights into transport across NPCs within cells and at nanometer and millisecond scales.
shorturl.at/2ClQp
shorturl.at/2ClQp
Vector-borne viral pathogens are threats to crops, and so trigger plant immune responses. Studying rice, authors @nature provide molecular-level insights into the first steps of plant antiviral response.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Perception of viral infections and initiation of antiviral defence in rice - Nature
Viral coat proteins are perceived by the RING1–IBR–RING2-type ubiquitin ligase, initiating the first step of the natural antiviral response in rice.
www.nature.com
March 12, 2025 at 7:47 PM
Vector-borne viral pathogens are threats to crops, and so trigger plant immune responses. Studying rice, authors @nature provide molecular-level insights into the first steps of plant antiviral response.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
While work @nature recently showed that the TIR1/AFB receptors of the plant hormone auxin have adenylate cyclase activity, further work now shows the broad physiological significance of this activity during plant development, via transcriptional reprogramming.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
TIR1-produced cAMP as a second messenger in transcriptional auxin signalling - Nature
cAMP produced by the TIR1/AFB receptors of the main endogenous developmental plant hormone auxin acts as a true second messenger, revising the established paradigm of transcriptional auxin signalling.
www.nature.com
March 5, 2025 at 4:03 PM
While work @nature recently showed that the TIR1/AFB receptors of the plant hormone auxin have adenylate cyclase activity, further work now shows the broad physiological significance of this activity during plant development, via transcriptional reprogramming.
www.nature.com/articles/s41...
www.nature.com/articles/s41...