@sreekarmantena.bsky.social
MD/PhD Trainee @ Harvard/MIT studying statistics & medicine | Passionate about all things 🧬 immunogenomics, 🌎 global health, and 📷 photography
Excited to share our preprint studying the genetics of T cell receptors! bit.ly/tcrdiversity with @soumya-boston.bsky.social @broadinstitute.org 🧵
TCR germline diversity reveals evidence of natural selection on variable and joining alpha chain genes
T cell receptors (TCRs) orchestrate adaptive immunity, yet the complex, repetitive architecture of the TCR loci has impeded systematic characterization of human genetic variation in the genes encoding...
doi.org
August 29, 2025 at 6:15 PM
Excited to share our preprint studying the genetics of T cell receptors! bit.ly/tcrdiversity with @soumya-boston.bsky.social @broadinstitute.org 🧵