Sofia Morfopoulou
smorfopoulou.bsky.social
Sofia Morfopoulou
@smorfopoulou.bsky.social
Clinical metagenomics and pathogen genomics - bioinformatics, computational statistics, infectious diseases. UCL
Pinned
We have a fully-funded computational PhD project available in our lab at Institute of Child Health UCL, examining how we can combine metagenomics and host transcriptomics to enable better diagnosis/stratification of infectious illnesses. Deadline 13/12.
Reposted by Sofia Morfopoulou
Happy to share the first preprint from my lab. Great work by Lewis Fisher and collaboration with Jukka Corander
www.biorxiv.org/content/10.1...
High frequency body site translocation of nosocomial Pseudomonas aeruginosa
Pseudomonas aeruginosa is an important nosocomial pathogen which can cause serious infections across diverse anatomic locations. Infections can spread within an individual to different body sites, but...
www.biorxiv.org
May 1, 2025 at 6:32 AM
Reposted by Sofia Morfopoulou
This paper has been a long time coming: We looked at the genomes of historical bacterial samples over a century to look for trends of antibiotic resistance genes, finding multiple instances of them in infections before the age of antibiotics, but an increase in both frequency and mobility after
Genomic resistance in historical clinical isolates increased in frequency and mobility after the age of antibiotics https://www.biorxiv.org/content/10.1101/2025.01.16.633422v1
January 17, 2025 at 8:53 PM
Reposted by Sofia Morfopoulou
JOIN US!

✍️Two predoc positions:

lavoraconnoi.unitn.it/en/research-...

✍️Two postdoc positions:

lavoraconnoi.unitn.it/en/research-...

lavoraconnoi.unitn.it/en/research-...

Deadline for application: January 31

Feel free to contact Nicola Segata for any Qs!
a sign that says `` join us '' on a black background .
Alt: a sign that says `` join us '' on a black background .
media.tenor.com
January 15, 2025 at 1:17 PM
Reposted by Sofia Morfopoulou
We are recruiting 2 postdocs to help us understand the mechanisms underlying HSV-1 latency.

You will be part of a collaborative team & receive extensive mentorship to develop your own independent line of research. #stemcells #virology

Please share 🙏

careers.humantechnopole.it/o/postdoc-ha...
Human Technopole - Postdocs - Harschnitz group - funded by FIS
APPLICATION CLOSING DATE: February 5th 2025Human Technopole (HT) is an interdisciplinary research institute in Milan (Italy) created and supported by the Italian government to develop innovative strat
careers.humantechnopole.it
January 16, 2025 at 9:54 AM
Reposted by Sofia Morfopoulou
Adults are failing to protect children, big time

“Nearly one in five of the world’s children live in areas affected by conflicts, with more than 473 million children suffering from the worst levels of violence since the 2nd World War”

www.theguardian.com/society/2024...
Almost one in five children live in conflict zones, says Unicef
UN humanitarian body warns that dramatic increase in harm to children should not become the ‘new normal’
www.theguardian.com
December 28, 2024 at 7:06 PM
Reposted by Sofia Morfopoulou
Fascinating paper on individual setpoints for blood count variables. Much better risk estimation when you interpret any given measurement from a person in light of all previous measurements. And I bet it is applicable much more widely to other blood tests. www.nature.com/articles/s41...
Haematological setpoints are a stable and patient-specific deep phenotype - Nature
Complete blood count indices are tightly regulated around setpoints for decades in healthy adults, and represent a deep phenotype providing opportunities for investigating differential disease risks, ...
www.nature.com
December 14, 2024 at 3:10 PM
Reposted by Sofia Morfopoulou
Last few days to apply for this computational PhD project with me and @smorfopoulou.bsky.social
Come work with me, @cristinaventurini.bsky.social and Prof. Breuer. Please spread the word! And do get in touch if interested.
More details here:
www.ucl.ac.uk/child-health...
Apply here:
www.ucl.ac.uk/child-health...
December 9, 2024 at 3:18 PM
Reposted by Sofia Morfopoulou
@UKHSA latest respiratory surveillance released.

1.flu positivity and hospitalisations rising fast - earlier than last year and exponential growth

2. RSV remains high but looks like it is close to peak - highest rates in children under 5.

3. COVID at low levels and stable.
December 5, 2024 at 2:12 PM
9 days left to apply! Please spread the word and share with anyone you think might be interested.
We have a fully-funded computational PhD project available in our lab at Institute of Child Health UCL, examining how we can combine metagenomics and host transcriptomics to enable better diagnosis/stratification of infectious illnesses. Deadline 13/12.
December 4, 2024 at 7:59 AM
We have a fully-funded computational PhD project available in our lab at Institute of Child Health UCL, examining how we can combine metagenomics and host transcriptomics to enable better diagnosis/stratification of infectious illnesses. Deadline 13/12.
November 29, 2024 at 10:06 AM
Reposted by Sofia Morfopoulou
We are truly failing our children by not protecting them 😔

Measles cases rose to more than 10 million in 2023!

www.nbcnews.com/health/healt...
Measles cases rose to more than 10 million in 2023, WHO and CDC say
The surge in the preventable disease was driven by “inadequate immunization coverage,” the agencies said.
www.nbcnews.com
November 23, 2024 at 5:54 AM