@SimonSuppinger
@simonsuppinger.bsky.social
PhD Student in the Liberali Lab | Symmetry-breaking in Gastruloids and Blastoids
Reposted by @SimonSuppinger
Are you working with OME-Zarrs in Switzerland?
We're running a series of community events in the context of the BioFAIR project of the BioVisionCenter: Monthly Open Bioimaging Practices Meetups with presentations by us & community members. Starting off with 3 cool events this fall (see image) (1/6)
We're running a series of community events in the context of the BioFAIR project of the BioVisionCenter: Monthly Open Bioimaging Practices Meetups with presentations by us & community members. Starting off with 3 cool events this fall (see image) (1/6)
September 16, 2025 at 7:46 AM
Are you working with OME-Zarrs in Switzerland?
We're running a series of community events in the context of the BioFAIR project of the BioVisionCenter: Monthly Open Bioimaging Practices Meetups with presentations by us & community members. Starting off with 3 cool events this fall (see image) (1/6)
We're running a series of community events in the context of the BioFAIR project of the BioVisionCenter: Monthly Open Bioimaging Practices Meetups with presentations by us & community members. Starting off with 3 cool events this fall (see image) (1/6)
Reposted by @SimonSuppinger
🚨We're hiring! Join a global team at the @priscaliberali.bsky.social lab & the @alleninstitute.org to build cutting-edge image analysis workflows for complex biological datasets, including light-sheet microscopy images. Apply at: www.fmi.ch/education-ca...
June 11, 2025 at 10:36 AM
🚨We're hiring! Join a global team at the @priscaliberali.bsky.social lab & the @alleninstitute.org to build cutting-edge image analysis workflows for complex biological datasets, including light-sheet microscopy images. Apply at: www.fmi.ch/education-ca...
Interested in organoid & stem cell research?! The Liberali Lab (FMI, Basel/ BSSE, ETH) & Allen Institute (Seattle) seek a Research Associate with iPSC/organoid expertise for a unique collaboration. Advance tissue morphogenesis with cutting-edge imaging & genome engineering. Apply Now!
We're seeking a Research Associate in stem cell biology to join a global, interdisciplinary team investigating organoids and tissue organization. This unique role is part of a collaboration between the @priscaliberali.bsky.social lab & the @alleninstitute.org. Apply at: www.fmi.ch/education-ca...
June 12, 2025 at 2:16 PM
Interested in organoid & stem cell research?! The Liberali Lab (FMI, Basel/ BSSE, ETH) & Allen Institute (Seattle) seek a Research Associate with iPSC/organoid expertise for a unique collaboration. Advance tissue morphogenesis with cutting-edge imaging & genome engineering. Apply Now!
Reposted by @SimonSuppinger
If you look for an easy way to plot OME-zarr images in your scripts, I hope the ez-zarr python package will be useful:
Just published in JOSS: 'ez-zarr: A Python package for easy access and visualisation of OME-Zarr filesets' https://doi.org/10.21105/joss.07882
May 18, 2025 at 7:30 AM
If you look for an easy way to plot OME-zarr images in your scripts, I hope the ez-zarr python package will be useful:
Reposted by @SimonSuppinger
There’s been much talk of the brain drain away from the US in response to the sweeping cuts in funding & research positions. Here’s our summary to the initiatives designed to provide ‘a home’ to those who consider leaving
@nature.com
#AcademicSky 🧪
www.nature.com/articles/d41...
@nature.com
#AcademicSky 🧪
www.nature.com/articles/d41...
US brain drain: Nature’s guide to the initiatives drawing scientists abroad
In response to US turmoil, premier establishments such as the European Research Council have sweetened incentives to attract talent.
www.nature.com
May 16, 2025 at 2:55 PM
There’s been much talk of the brain drain away from the US in response to the sweeping cuts in funding & research positions. Here’s our summary to the initiatives designed to provide ‘a home’ to those who consider leaving
@nature.com
#AcademicSky 🧪
www.nature.com/articles/d41...
@nature.com
#AcademicSky 🧪
www.nature.com/articles/d41...
Reposted by @SimonSuppinger
IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply by May 18: imba.science/beagroupleader #hiring #biology #research #groupleader #europe
May 14, 2025 at 7:00 AM
IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply by May 18: imba.science/beagroupleader #hiring #biology #research #groupleader #europe
Reposted by @SimonSuppinger
Extracellular volume expansion drives vertebrate axis elongation: Current Biology www.cell.com/current-biol...
Extracellular volume expansion drives vertebrate axis elongation
Michaut et al. show that presomitic mesoderm explants autonomously elongate by a graded
increase of the extracellular volume. Explant elongation mainly depends on cell activity
and little on prolifera...
www.cell.com
January 29, 2025 at 5:13 PM
Extracellular volume expansion drives vertebrate axis elongation: Current Biology www.cell.com/current-biol...
Reposted by @SimonSuppinger
With pleasure we share our preprint reporting robust and cost-effective expansion of naive human Pluripotent Stem Cells without feeder cells. A fantastic collaborative effort with @leeboratory.bsky.social @jzylicz.bsky.social @pasquelab.bsky.social and Nicolas Rivron.
tinyurl.com/5n6z9rt9
tinyurl.com/5n6z9rt9
January 21, 2025 at 10:44 AM
With pleasure we share our preprint reporting robust and cost-effective expansion of naive human Pluripotent Stem Cells without feeder cells. A fantastic collaborative effort with @leeboratory.bsky.social @jzylicz.bsky.social @pasquelab.bsky.social and Nicolas Rivron.
tinyurl.com/5n6z9rt9
tinyurl.com/5n6z9rt9
Reposted by @SimonSuppinger
A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration. 🧵 biorxiv.org/cgi/content/...
Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration
Tissue regeneration relies on the ability of cells to undergo de novo patterning. While tissue patterning has been viewed as the transition from initially identical un-patterned cells to an arrangemen...
biorxiv.org
January 15, 2025 at 5:32 PM
A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration. 🧵 biorxiv.org/cgi/content/...
Reposted by @SimonSuppinger
Proud to share our paper on the impact of transcription inhibition on mRNA export in cancer.
A big thanks to collaborators, especially to Ewa Michalak, Vi Wickramasinghe, Jeff Chao and Mark Dawson @mafdawson.bsky.social. @fmiscience.bsky.social
A big thanks to collaborators, especially to Ewa Michalak, Vi Wickramasinghe, Jeff Chao and Mark Dawson @mafdawson.bsky.social. @fmiscience.bsky.social
Why can a human tolerate a drug that globally inhibits transcription? Why do transcription inhibitors not cure cancer? Our first paper of 2025 may help explain (some) of this!
So incredibly proud of @tobiaswilliams.bsky.social & Ewa Michalak who led the work!
www.cell.com/molecular-ce...
So incredibly proud of @tobiaswilliams.bsky.social & Ewa Michalak who led the work!
www.cell.com/molecular-ce...
mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription
Transcription inhibitors also disrupt nuclear export. Here, Williams et al. reveal that mRNA export factors sense transcription inhibition and adapt by storing mature export-competent mRNA in nuclear speckles. This enables rapid release when transcription resumes and ensures retention of cellular identity and viability during a transient global transcription insult.
www.cell.com
January 2, 2025 at 10:55 PM
Proud to share our paper on the impact of transcription inhibition on mRNA export in cancer.
A big thanks to collaborators, especially to Ewa Michalak, Vi Wickramasinghe, Jeff Chao and Mark Dawson @mafdawson.bsky.social. @fmiscience.bsky.social
A big thanks to collaborators, especially to Ewa Michalak, Vi Wickramasinghe, Jeff Chao and Mark Dawson @mafdawson.bsky.social. @fmiscience.bsky.social
Reposted by @SimonSuppinger
Our latest: how to generate the notochord
"Timely TGFβ signalling inhibition induces notochord"
A thread:
www.nature.com/articles/s41...
"Timely TGFβ signalling inhibition induces notochord"
A thread:
www.nature.com/articles/s41...
Timely TGFβ signalling inhibition induces notochord - Nature
Through analysis of developing chick embryos and in vitro differentiation of embryonic stem cells, a study develops a method to generate a model of the human trunk with a notochord.
www.nature.com
December 19, 2024 at 8:52 AM
Our latest: how to generate the notochord
"Timely TGFβ signalling inhibition induces notochord"
A thread:
www.nature.com/articles/s41...
"Timely TGFβ signalling inhibition induces notochord"
A thread:
www.nature.com/articles/s41...
Reposted by @SimonSuppinger
What if plate tectonics had something to do with development? We found a new framework for dynamic origami in tissue folding in a nerveless animal. Will share thread; but if you are at #cellbio2024, see @cbrannon.bsky.social poster B399 today.
Not at ASCB; read www.biorxiv.org/content/10.1...
Not at ASCB; read www.biorxiv.org/content/10.1...
December 17, 2024 at 4:38 PM
What if plate tectonics had something to do with development? We found a new framework for dynamic origami in tissue folding in a nerveless animal. Will share thread; but if you are at #cellbio2024, see @cbrannon.bsky.social poster B399 today.
Not at ASCB; read www.biorxiv.org/content/10.1...
Not at ASCB; read www.biorxiv.org/content/10.1...
Apply! FMI is an amazing place with unique opportunities!
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
December 17, 2024 at 7:34 AM
Apply! FMI is an amazing place with unique opportunities!
Reposted by @SimonSuppinger
If you are attending #CellBio2024 and are interested in understanding how the process of crypt morphogenesis is coordinated both in vivo and in organoids then come to my talk Wed Dec 18th in the subgroup “Organoids as tools to study the function of tissue in Health and Disease”
December 15, 2024 at 7:09 PM
If you are attending #CellBio2024 and are interested in understanding how the process of crypt morphogenesis is coordinated both in vivo and in organoids then come to my talk Wed Dec 18th in the subgroup “Organoids as tools to study the function of tissue in Health and Disease”