Sidrit Uruci (Sid)
@sidrituruci.bsky.social
PhD in @luijsterburglab at @LUMC_Leiden, previously in @Tanejalab at @ErasmusMC.
Science lover, DNA enthusiast.
European child 🇪🇺🇳🇱🇮🇹🇦🇱🏳️🌈
Science lover, DNA enthusiast.
European child 🇪🇺🇳🇱🇮🇹🇦🇱🏳️🌈
Reposted by Sidrit Uruci (Sid)
Happy to share I have been promoted to Full Professor of Transcription and DNA Repair! Huge thanks to all current and former Luijsterburg Lab members. Your hard work, dedication, and inspiring spirit made this possible! 💥🧬🙏 www.luijsterburglab.org
August 1, 2025 at 7:14 AM
Happy to share I have been promoted to Full Professor of Transcription and DNA Repair! Huge thanks to all current and former Luijsterburg Lab members. Your hard work, dedication, and inspiring spirit made this possible! 💥🧬🙏 www.luijsterburglab.org
Reposted by Sidrit Uruci (Sid)
A must for all DNA repair aficionados!
Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱
✔️ Confirmed top speakers
✔️ Ample opportunities for talks & posters
Don’t miss it: dnarepairmeeting-egmond2026.com
Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱
✔️ Confirmed top speakers
✔️ Ample opportunities for talks & posters
Don’t miss it: dnarepairmeeting-egmond2026.com
April 9, 2025 at 8:05 AM
A must for all DNA repair aficionados!
Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱
✔️ Confirmed top speakers
✔️ Ample opportunities for talks & posters
Don’t miss it: dnarepairmeeting-egmond2026.com
Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱
✔️ Confirmed top speakers
✔️ Ample opportunities for talks & posters
Don’t miss it: dnarepairmeeting-egmond2026.com
Reposted by Sidrit Uruci (Sid)
I am delighted to share the main work of my PhD project in the @hamperllab.bsky.social now out in @narjournal.bsky.social. TRCs drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery.
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
Transcription-replication conflicts drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery
Abstract. Progressing transcription and replication machineries profoundly impact their underlying chromatin template. Consequently, transcription-replicat
academic.oup.com
February 20, 2025 at 1:38 PM
I am delighted to share the main work of my PhD project in the @hamperllab.bsky.social now out in @narjournal.bsky.social. TRCs drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery.
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
Reposted by Sidrit Uruci (Sid)
Very happy to share that our work on identifying and characterizing factors affecting DNA replication is published by Nature Communications!
We present Repli-ID, an approach to identify proteins affecting DNA replication. Lge1 and Rox1 are new regulators of this process. Great work by @sophievdhorst.bsky.social, @lleonie.bsky.social and co-authors in collaboration with @andreichabes.bsky.social.
tinyurl.com/mvvcp3xe
tinyurl.com/mvvcp3xe
Replication-IDentifier links epigenetic and metabolic pathways to the replication stress response - Nature Communications
Cells activate various pathways to counter DNA replication stress. Using Replication-IDentifier (Repli-ID), the authors identified 423 genes, including LGE1 and ROX1, linking epigenetic and metabolic ...
tinyurl.com
February 8, 2025 at 8:51 PM
Very happy to share that our work on identifying and characterizing factors affecting DNA replication is published by Nature Communications!
Reposted by Sidrit Uruci (Sid)
RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription https://www.biorxiv.org/content/10.1101/2024.11.20.622938v1
RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription https://www.biorxiv.org/content/10.1101/2024.11.20.622938v1
Independently of the pathways or circuits deregulated in cancer cells, these present altered transcr
www.biorxiv.org
November 21, 2024 at 5:17 AM
RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription https://www.biorxiv.org/content/10.1101/2024.11.20.622938v1