Shahar Sukenik
@shaharsu.bsky.social
Alternating between running a lab at UC Merced and taking care of the kids. Tweets mostly science related.
Reposted by Shahar Sukenik
The First Annual Virtual WALII Symposium: Exploring Life Without Water is ONE WEEK AWAY! 🗓️💧
Register now to join us on November, 18!
www.walii.science/virtual-symp...
Register now to join us on November, 18!
www.walii.science/virtual-symp...
November 11, 2025 at 7:37 PM
The First Annual Virtual WALII Symposium: Exploring Life Without Water is ONE WEEK AWAY! 🗓️💧
Register now to join us on November, 18!
www.walii.science/virtual-symp...
Register now to join us on November, 18!
www.walii.science/virtual-symp...
Reposted by Shahar Sukenik
🚨🚨The GRC on Intrinsically Disordered Proteins #IDPs is back!! 🍝🧵🏔️Join us for cutting-edge IDP science, great discussions, and mountain views 🌄🍝
📅 June 21-26, 2026 | Les Diablerets, Switzerland
👉 Details & registration: grc.org/intrinsicall...
📅 June 21-26, 2026 | Les Diablerets, Switzerland
👉 Details & registration: grc.org/intrinsicall...
2026 Intrinsically Disordered Proteins Conference GRC
The 2026 Gordon Research Conference on Intrinsically Disordered Proteins will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.
grc.org
October 2, 2025 at 3:21 PM
🚨🚨The GRC on Intrinsically Disordered Proteins #IDPs is back!! 🍝🧵🏔️Join us for cutting-edge IDP science, great discussions, and mountain views 🌄🍝
📅 June 21-26, 2026 | Les Diablerets, Switzerland
👉 Details & registration: grc.org/intrinsicall...
📅 June 21-26, 2026 | Les Diablerets, Switzerland
👉 Details & registration: grc.org/intrinsicall...
Reposted by Shahar Sukenik
🚨The 2026 IDP GRC Program is LIVE! 📣
Check it out: www.grc.org/intrinsicall...
We’ve got an incredible speaker lineup! 🌟
Over the next few weeks, we’ll be highlighting some of them and giving you a sneak peek at the exciting topics they’ll be covering. Stay tuned!
Check it out: www.grc.org/intrinsicall...
We’ve got an incredible speaker lineup! 🌟
Over the next few weeks, we’ll be highlighting some of them and giving you a sneak peek at the exciting topics they’ll be covering. Stay tuned!
2026 Intrinsically Disordered Proteins Conference GRC
The 2026 Gordon Research Conference on Intrinsically Disordered Proteins will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.
www.grc.org
October 7, 2025 at 3:17 PM
🚨The 2026 IDP GRC Program is LIVE! 📣
Check it out: www.grc.org/intrinsicall...
We’ve got an incredible speaker lineup! 🌟
Over the next few weeks, we’ll be highlighting some of them and giving you a sneak peek at the exciting topics they’ll be covering. Stay tuned!
Check it out: www.grc.org/intrinsicall...
We’ve got an incredible speaker lineup! 🌟
Over the next few weeks, we’ll be highlighting some of them and giving you a sneak peek at the exciting topics they’ll be covering. Stay tuned!
Reposted by Shahar Sukenik
🎉Excited to announce that Dr. Rebecca Berlow @berlowlab.bsky.social
will speak in the “Disorder in Pathogens” session at #IDPGRC2026!
The Berlow lab uses solution NMR and biophysical approaches to uncover how IDP sequence, dynamics & function drive transcriptional regulation.
will speak in the “Disorder in Pathogens” session at #IDPGRC2026!
The Berlow lab uses solution NMR and biophysical approaches to uncover how IDP sequence, dynamics & function drive transcriptional regulation.
October 8, 2025 at 2:48 PM
🎉Excited to announce that Dr. Rebecca Berlow @berlowlab.bsky.social
will speak in the “Disorder in Pathogens” session at #IDPGRC2026!
The Berlow lab uses solution NMR and biophysical approaches to uncover how IDP sequence, dynamics & function drive transcriptional regulation.
will speak in the “Disorder in Pathogens” session at #IDPGRC2026!
The Berlow lab uses solution NMR and biophysical approaches to uncover how IDP sequence, dynamics & function drive transcriptional regulation.
Reposted by Shahar Sukenik
🖥️Next up: Jeetain Mittal in the Material Properties of IDPs and Condensates session! His team uses multiscale simulations to uncover how sequence-encoded interactions in IDPs govern conformational transitions & condensate behavior - informing neurodegenerative research. @mittalgrouptamu.bsky.social
October 28, 2025 at 10:24 AM
🖥️Next up: Jeetain Mittal in the Material Properties of IDPs and Condensates session! His team uses multiscale simulations to uncover how sequence-encoded interactions in IDPs govern conformational transitions & condensate behavior - informing neurodegenerative research. @mittalgrouptamu.bsky.social
Reposted by Shahar Sukenik
📢 Abstract deadline Nov 1!
Join us at the FASEB Conference on Biomolecular Phase Transitions (Jan 11–15, 2026, Melbourne, FL), showcasing cutting-edge research on condensates in health & disease, and therapeutic frontiers.
~30% talks from abstracts!
events.faseb.org/event/480194...
Join us at the FASEB Conference on Biomolecular Phase Transitions (Jan 11–15, 2026, Melbourne, FL), showcasing cutting-edge research on condensates in health & disease, and therapeutic frontiers.
~30% talks from abstracts!
events.faseb.org/event/480194...
Phase Transitions in Cellular Signaling and Disease.
Explore biomolecular condensates, phase transitions, and drug discovery in Florida. Hear from experts, attend workshops, and advance your research!
events.faseb.org
October 27, 2025 at 1:38 PM
📢 Abstract deadline Nov 1!
Join us at the FASEB Conference on Biomolecular Phase Transitions (Jan 11–15, 2026, Melbourne, FL), showcasing cutting-edge research on condensates in health & disease, and therapeutic frontiers.
~30% talks from abstracts!
events.faseb.org/event/480194...
Join us at the FASEB Conference on Biomolecular Phase Transitions (Jan 11–15, 2026, Melbourne, FL), showcasing cutting-edge research on condensates in health & disease, and therapeutic frontiers.
~30% talks from abstracts!
events.faseb.org/event/480194...
Thanks @elevylab.bsky.social for a fantastic writeup!!
Molecular Armor: Simple Rules to Keep Proteins (Re)Soluble💧
Check our preview of a cool study on how proteins stay soluble (or not) after desiccation—from the labs of S. Fried, @alexholehouse.bsky.social and @shaharsu.bsky.social in @cp-cellsystems.bsky.social
www.sciencedirect.com/science/arti...
Check our preview of a cool study on how proteins stay soluble (or not) after desiccation—from the labs of S. Fried, @alexholehouse.bsky.social and @shaharsu.bsky.social in @cp-cellsystems.bsky.social
www.sciencedirect.com/science/arti...
October 16, 2025 at 9:48 AM
Thanks @elevylab.bsky.social for a fantastic writeup!!
Can't wait to see you all there!!
🚨🚨The GRC on Intrinsically Disordered Proteins #IDPs is back!! 🍝🧵🏔️Join us for cutting-edge IDP science, great discussions, and mountain views 🌄🍝
📅 June 21-26, 2026 | Les Diablerets, Switzerland
👉 Details & registration: grc.org/intrinsicall...
📅 June 21-26, 2026 | Les Diablerets, Switzerland
👉 Details & registration: grc.org/intrinsicall...
2026 Intrinsically Disordered Proteins Conference GRC
The 2026 Gordon Research Conference on Intrinsically Disordered Proteins will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.
grc.org
October 3, 2025 at 1:40 PM
Can't wait to see you all there!!
Reposted by Shahar Sukenik
The power of collaborations! With @shaharsu.bsky.social, his PD @jessniblo.bsky.social and CALVADOS3 (thanks to @lindorfflarsen.bsky.social ) we show how STI1 (red) may engage with sequences that match transient helices within IDRs of Ub-binding shuttle protein Dsk2 www.biorxiv.org/content/10.1...
May 23, 2025 at 1:18 PM
The power of collaborations! With @shaharsu.bsky.social, his PD @jessniblo.bsky.social and CALVADOS3 (thanks to @lindorfflarsen.bsky.social ) we show how STI1 (red) may engage with sequences that match transient helices within IDRs of Ub-binding shuttle protein Dsk2 www.biorxiv.org/content/10.1...
Reposted by Shahar Sukenik
Announcing the joint @idpseminars.bsky.social / BPS IDP Subgroup Trainee Symposium Speakers!
Join us on Mar 27, 12–2pm CST for 6 exciting talks focused on Intrinsically Disordered Proteins as part of #BophysicsWeek2025 with the @biophysicalsoc.bsky.social Sign up now using the QR code below!
Join us on Mar 27, 12–2pm CST for 6 exciting talks focused on Intrinsically Disordered Proteins as part of #BophysicsWeek2025 with the @biophysicalsoc.bsky.social Sign up now using the QR code below!
March 17, 2025 at 3:38 PM
Announcing the joint @idpseminars.bsky.social / BPS IDP Subgroup Trainee Symposium Speakers!
Join us on Mar 27, 12–2pm CST for 6 exciting talks focused on Intrinsically Disordered Proteins as part of #BophysicsWeek2025 with the @biophysicalsoc.bsky.social Sign up now using the QR code below!
Join us on Mar 27, 12–2pm CST for 6 exciting talks focused on Intrinsically Disordered Proteins as part of #BophysicsWeek2025 with the @biophysicalsoc.bsky.social Sign up now using the QR code below!
Reposted by Shahar Sukenik
📢 Excited to share our research with @shaharsu.bsky.social & @mvstaller.bsky.social on how activation domain (AD) structure affects gene expression! 🧬 TLDR: HIF-1α & CITED2 ADs suggest ensemble dimensions may regulate transcription in unique ways.
www.cell.com/biophysrepor...
🧵 Highlights:
www.cell.com/biophysrepor...
🧵 Highlights:
February 26, 2025 at 7:03 AM
📢 Excited to share our research with @shaharsu.bsky.social & @mvstaller.bsky.social on how activation domain (AD) structure affects gene expression! 🧬 TLDR: HIF-1α & CITED2 ADs suggest ensemble dimensions may regulate transcription in unique ways.
www.cell.com/biophysrepor...
🧵 Highlights:
www.cell.com/biophysrepor...
🧵 Highlights:
Reposted by Shahar Sukenik
Excited to announce the newest member of the flock - STARLING (conSTruction of intrinsicAlly disoRdered proteins ensembles efficientLy vIa multi-dimeNsional Generative models).
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
February 15, 2025 at 7:27 PM
Excited to announce the newest member of the flock - STARLING (conSTruction of intrinsicAlly disoRdered proteins ensembles efficientLy vIa multi-dimeNsional Generative models).
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Shahar Sukenik
The STARLING has landed - excited to share new work from @bornanovak.bsky.social and @jefflotthammer.bsky.social in what is also Borna's first Bluesky post!
If you're at BPS, I'll be speaking about this this afternoon in IDP SG, and Borna and Jeff both have posters (Sunday B112 and Wed B152).
If you're at BPS, I'll be speaking about this this afternoon in IDP SG, and Borna and Jeff both have posters (Sunday B112 and Wed B152).
Excited to announce the newest member of the flock - STARLING (conSTruction of intrinsicAlly disoRdered proteins ensembles efficientLy vIa multi-dimeNsional Generative models).
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
February 15, 2025 at 7:33 PM
The STARLING has landed - excited to share new work from @bornanovak.bsky.social and @jefflotthammer.bsky.social in what is also Borna's first Bluesky post!
If you're at BPS, I'll be speaking about this this afternoon in IDP SG, and Borna and Jeff both have posters (Sunday B112 and Wed B152).
If you're at BPS, I'll be speaking about this this afternoon in IDP SG, and Borna and Jeff both have posters (Sunday B112 and Wed B152).
Reposted by Shahar Sukenik
Announcing the Biophysics Week IDP Trainee Symposium on March 27 at 12pm CT hosted by @idpseminars.bsky.social & The BPS IDP Subgroup! Join via Zoom for talks by talented grad students & postdocs. Abstract submissions are open! See flyer for more details! #BiophysicsWeek @biophysicalsoc.bsky.social
February 7, 2025 at 6:31 PM
Announcing the Biophysics Week IDP Trainee Symposium on March 27 at 12pm CT hosted by @idpseminars.bsky.social & The BPS IDP Subgroup! Join via Zoom for talks by talented grad students & postdocs. Abstract submissions are open! See flyer for more details! #BiophysicsWeek @biophysicalsoc.bsky.social
🎉🧪New perspective paper! Single-point missense mutations are common in disordered regions but are often overlooked👀. We analyzed thousands of IDR point mutations associated with human congenital diseases to show that many can significantly change local IDR ensemble structure!
shorturl.at/iIbLX
shorturl.at/iIbLX
February 7, 2025 at 7:55 PM
🎉🧪New perspective paper! Single-point missense mutations are common in disordered regions but are often overlooked👀. We analyzed thousands of IDR point mutations associated with human congenital diseases to show that many can significantly change local IDR ensemble structure!
shorturl.at/iIbLX
shorturl.at/iIbLX
Reposted by Shahar Sukenik
We're back for 2025! This week we welcome Adam Klosin and Randal Halfmann for the first IDPSeminar of Season 17!
January 7, 2025 at 5:22 PM
We're back for 2025! This week we welcome Adam Klosin and Randal Halfmann for the first IDPSeminar of Season 17!
Reposted by Shahar Sukenik
New collaborative work in collaboration with the labs of Robert Best & Tanja Mittag driven by Ben Schuler.
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations.
pubs.acs.org/doi/10.1021/...
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations.
pubs.acs.org/doi/10.1021/...
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations
It has become increasingly evident that the conformational distributions of intrinsically disordered proteins or regions are strongly dependent on their amino acid compositions and sequence. To facili...
pubs.acs.org
November 15, 2024 at 4:56 PM
New collaborative work in collaboration with the labs of Robert Best & Tanja Mittag driven by Ben Schuler.
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations.
pubs.acs.org/doi/10.1021/...
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations.
pubs.acs.org/doi/10.1021/...
Reposted by Shahar Sukenik
Last chance to submit your abstract (deadline Tuesday, Feb 20!) for posters & talks for the upcoming EMBO/EMBL Symposium "Cellular mechanisms driven by phase separation", taking place May 14-17 2024 in Heidelberg
www.embl.org/about/info/c...
www.embl.org/about/info/c...
Cellular mechanisms driven by phase separation
www.embl.org
February 19, 2024 at 3:47 PM
Last chance to submit your abstract (deadline Tuesday, Feb 20!) for posters & talks for the upcoming EMBO/EMBL Symposium "Cellular mechanisms driven by phase separation", taking place May 14-17 2024 in Heidelberg
www.embl.org/about/info/c...
www.embl.org/about/info/c...
🎉Finally out! Our paper shows that intramolecular interactions in disordered proteins 🍝 can be strong enough to hold inside the cell. 2 years in the making and a labor of love of many people, including @alexholehouse.bsky.social. rdcu.be/du9TY
January 4, 2024 at 2:39 PM
🎉Finally out! Our paper shows that intramolecular interactions in disordered proteins 🍝 can be strong enough to hold inside the cell. 2 years in the making and a labor of love of many people, including @alexholehouse.bsky.social. rdcu.be/du9TY
Reposted by Shahar Sukenik
Today presenting alongside Benedetta Bolognesi in the Condensate Colloquium Series. Not on Bluesky yet, so must shamelessly self-promote, see yours later :-)
Also, repost appreciated 🙏
Also, repost appreciated 🙏
November 21, 2023 at 10:28 AM
Today presenting alongside Benedetta Bolognesi in the Condensate Colloquium Series. Not on Bluesky yet, so must shamelessly self-promote, see yours later :-)
Also, repost appreciated 🙏
Also, repost appreciated 🙏
Reposted by Shahar Sukenik
A labor of love - our review on why IDRs matter for cellular function is live in Nat. Rev. Mol. Cell. Biol:
www.nature.com/articles/s41...
Working with Birthe Kraglund on this was such a pleasure, and we hope this review will be helpful to a broad audience!
www.nature.com/articles/s41...
Working with Birthe Kraglund on this was such a pleasure, and we hope this review will be helpful to a broad audience!
November 13, 2023 at 2:56 PM
A labor of love - our review on why IDRs matter for cellular function is live in Nat. Rev. Mol. Cell. Biol:
www.nature.com/articles/s41...
Working with Birthe Kraglund on this was such a pleasure, and we hope this review will be helpful to a broad audience!
www.nature.com/articles/s41...
Working with Birthe Kraglund on this was such a pleasure, and we hope this review will be helpful to a broad audience!