Carsten Sachse
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sachsegroup.bsky.social
Carsten Sachse
@sachsegroup.bsky.social
The Sachse group @fz_juelich: #cryoEM #cryoET #CLEM #FIBSEM #autophagy.
Reposted by Carsten Sachse
Grateful to have received the Wilhelm und Else Heraeus-Stiftung Research Fellowship, to support my group’s work at the Ernst Ruska-Centre (ER-C) of Forschungszentrum Jülich #cryoem
November 9, 2025 at 9:26 AM
Reposted by Carsten Sachse
Finally in peer-reviewed form: Mapping the ultrastructural topology of the corynebacterial cell surface. @bupbuse.bsky.social @vikramalva.bsky.social

Please also see concurrent beautiful work from @adriasogues.bsky.social and Han Remaut.
The unique #CellEnvelope of #corynebacteria: @tbharat-lab.bsky.social &co map the C. glutamicum cell surface, revealing a patchy S-layer & specific assembly of the PS2 protein, thereby informing our understanding of cell envelopes that contain #MycolicAcids @plosbiology.org 🧪 plos.io/3Y6JNgw
April 23, 2025 at 2:07 PM
Reposted by Carsten Sachse
After years parked at a Polara, I’m excited to share that my PhD work is finally out! We figured out why imaging at liquid helium temperatures wasn’t working—and how to fix it.
🔗 www.pnas.org/doi/10.1073/...
Reducing the effects of radiation damage in cryo-EM using liquid helium temperatures | PNAS
The physical limit in determining the atomic structure of biological molecules is radiation damage. In electron cryomicroscopy, there have been num...
www.pnas.org
April 23, 2025 at 4:23 AM
Philipp's manuscript on our CryoVIA toolkit www.sciencedirect.com/science/arti... is out! For those interested in studying protein lipid interactions and high-throughput analysis of membrane structures (sizes, shapes, curvature etc.) - this could be your tool (github.com/philipp-scho...).
CryoVIA: An image analysis toolkit for the quantification of membrane structures from cryo-EM micrographs
Imaging of lipid structures and associated protein complexes using cryoelectron microscopy (cryo-EM) is a common visualization and structure determina…
www.sciencedirect.com
February 10, 2025 at 9:55 AM
Our first post on blue: grad student Philipp's software: for those interested in looking at membrane reconstitution by cryo-EM. Automated analysis of lipid fine structure and membrane shape classifications: biorxiv.org/cgi/content/...
CryoVIA - An image analysis toolkit for the quantification of membrane structures from cryo-EM micrographs
Imaging of lipid structures and associated protein complexes using electron cryo-microscopy (cryo-EM) is a common visualization and structure determination technique. The quantitative analysis of the ...
biorxiv.org
January 14, 2025 at 4:55 PM
Reposted by Carsten Sachse
Excited to share that I have been elected as member of the "Junge Kolleg" of the Nordrhein-Westfalian Academy of Sciences and Arts. I am honoured to have this opportunity to serve the community! Here's the link to the announcement, unfortunately only in German www.awk.nrw/news/nachwuc...
Nachwuchsförderung: Nordrhein-Westfälische Akademie nimmt neun neue Stipendiatinnen und Stipendiaten in ihr Junges Kolleg auf
Zum 1. Januar 2025 begrüßt die Nordrhein-Westfälische Akademie der Wissenschaften und der Künste neun weitere herausragende Talente in ihrem Jungen Kolleg. Sie haben die Jury in einem mehrstufigen Aus...
www.awk.nrw
December 18, 2024 at 10:48 AM