Roy Perlis, MD
Roy Perlis, MD
@royperlis.bsky.social
HMS Professor | EIC JAMA+ AI | Psychiatrist | Dad. Probably not Batman. Opinions my own or occasionally my dog’s
Happy to have the opportunity to highlight really lovely cellular modeling work by Orhan and colleagues in AJP ... endlessly boiling the genomic ocean is not sufficient to figure out brain diseases: psychiatryonline.org/doi/10.1176/...
Targeting Schizophrenia | American Journal of Psychiatry
PsychiatryOnline.org is the platform for all American Psychiatric Association Publishing journals, DSM, and bestselling textbooks, as well as APA Practice Guidelines, and continuing medical education.
psychiatryonline.org
April 1, 2025 at 12:40 PM
>I’m afraid code is getting unwieldy and bloated. How can we make it more maintainable?
You're absolutely right. The code has become unwieldy and bloated.

(Claude, that hurts my feelings a little....)
March 4, 2025 at 1:04 PM
Looking forward to speaking at BU's CTSI Translational Science Symposium on 3/19: "Advancing Translational Science Through Cutting-Edge Technology" ... registration here: www.bu.edu/ctsi/events/...
The 12th Annual CTSI Translational Science Symposium | Clinical & Translational Science Institute
www.bu.edu
March 3, 2025 at 8:25 PM
Hmm. I'm not sure this chatbot is quite ready for prime time.
March 1, 2025 at 9:42 PM
Working with the smaller (smol?) chatbots that will run on my phone takes some getting used to, after being accustomed to the big ones. I was just asked whether I'm feeling overwhelming today. (I am not.)
February 22, 2025 at 6:25 PM
Research Domain Criteria in NIMH Grants Characterized Using Large Language Models @JAMANetworkOpen
jamanetwork.com/journals/jam...
Research Domain Criteria in NIMH Grants Using Large Language Models
This cohort study uses a large language model to examine changes in research funding from the National Institute of Mental Health (NIMH) for Research Domain Criteria domains and transdiagnostic invest...
jamanetwork.com
February 13, 2025 at 2:21 AM
Reposted by Roy Perlis, MD
"The use of digital health technologies has steadily increased since the COVID-19 pandemic."

Cornelius James of the University of Michigan Medical School discusses the use of digital health technologies among older US adults with JAMA+ AI Editor in Chief @royperlis.bsky.social.

#MedSky
Which Digital Health Technologies Do Older Adults Use?
This Medical News article is an interview with Cornelius A. James, MD, of the University of Michigan Medical School about his recent research examining the use of digital health technologies, includin...
jamanetwork.com
February 7, 2025 at 4:40 PM
For those curious about the impact of the 15% IDC rate, here's data on total NIH funding by institution: brimr.org/brimr-rankin... ... and here's a brief synopsis of hardest-hit: www.forbes.com/sites/michae...
BRIMR Rankings of NIH Funding in 2023 | BRIMR
The Blue Ridge Institute for Medical Research publishes rankings of institutions, departments, and investigators based on the funding they receive from the NIH.
brimr.org
February 8, 2025 at 12:57 AM
6 fingers are the cherry on top: youtu.be/ua4rYsMdC4U?...
AI Software - SNL
YouTube video by Saturday Night Live
youtu.be
January 26, 2025 at 2:41 PM
LLM, asked about optimal treatment of depression, "Here are some additional things you can do: 1. **Get enough sleep**: Aim for 7-10 years of psychotherapy and 75-100% of CBT." Yeah, 7-10 years should just about do it.
December 31, 2024 at 3:19 PM
Reposted by Roy Perlis, MD
friend is a medical illustrator

few years ago, we were wondering when AI could do her job — getting the details right is important in this use case

since then, she's been noticing more and more news articles and such using AI generated medical images

note the 3rd forearm bone
December 23, 2024 at 7:14 PM
When you need a break from cute dogs and cool science facts and posts about how great it is here compared to that other place: jamanetwork.com/channels/ai
JAMA+ AI Research and Opinion Articles from JAMA Network
Explore clinical applications of AI in the JAMA Network, including research and opinion about the use of deep learning and neural networks for clinical image analysis, natural language processing, EHR...
jamanetwork.com
November 24, 2024 at 4:19 PM
Reposted by Roy Perlis, MD
Author Robert Califf, commissioner of the US Food and Drug Administration, joins JAMA+ AI Editor in Chief Roy Perlis to discuss AI regulation.

Listen to the episode: edhub.ama-assn.org/jn-learning/...
November 23, 2024 at 1:18 AM
so... 'Quantum Resistance' sounds like something from a Star Wars movie, but it's actually a strategy to protect against codebreaking by quantum computers that don't actually exist yet. Who knew? signal.org/blog/pqxdh/
Quantum Resistance and the Signal Protocol
The Signal Protocol is a set of cryptographic specifications that provides end-to-end encryption for private communications exchanged daily by billions of people around the world. After its publicatio...
signal.org
November 17, 2023 at 2:59 AM
Guess this is home now. (Taps microphone). This thing on?
November 17, 2023 at 2:18 AM