ross
@rosscloney.bsky.social
Chief Editor for Biotechnology at Nature Communications. This is gonna be mostly science, sometimes other stuff. All views my own. he/him
Prime editor with rational design and AI-driven optimization for reverse editing window and enhanced fidelity
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Prime editor with rational design and AI-driven optimization for reverse editing window and enhanced fidelity - Nature Communications
Expanding editing scope while reducing byproducts is now possible for prime editing. Here, authors develop reverse prime editing (rPE), a SpCas9-based tool enabling editing in reverse window with high...
www.nature.com
June 27, 2025 at 9:10 AM
Prime editor with rational design and AI-driven optimization for reverse editing window and enhanced fidelity
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Quite a lot of science today, let's dive right in
May 30, 2025 at 12:53 PM
Quite a lot of science today, let's dive right in
It's a sunny friday in London on the eve of a three day weekend. Let's have some science
May 2, 2025 at 1:00 PM
It's a sunny friday in London on the eve of a three day weekend. Let's have some science
The sun is out in London, I've got a new episode of The Wheel of Time to watch tonight, and you know what I think I might treat myself to a pizza. This is the Way (of having a good Friday).
But first, Friday science time!
But first, Friday science time!
March 28, 2025 at 1:41 PM
The sun is out in London, I've got a new episode of The Wheel of Time to watch tonight, and you know what I think I might treat myself to a pizza. This is the Way (of having a good Friday).
But first, Friday science time!
But first, Friday science time!
Time for some Friday Science!
March 21, 2025 at 8:54 AM
Time for some Friday Science!
Did someone say FRIDAY SCIENCE?
March 7, 2025 at 2:47 PM
Did someone say FRIDAY SCIENCE?
Time for some Friday Synbio!
February 28, 2025 at 1:55 PM
Time for some Friday Synbio!
Reposted by ross
Time for a Friday update!
This week I'm listening to:
Abracadabra - Lady Gaga
And reading:
The Lord of the Rings - J.R.R. Tolkien
Now onto the science...
This week I'm listening to:
Abracadabra - Lady Gaga
And reading:
The Lord of the Rings - J.R.R. Tolkien
Now onto the science...
February 21, 2025 at 1:52 PM
Time for a Friday update!
This week I'm listening to:
Abracadabra - Lady Gaga
And reading:
The Lord of the Rings - J.R.R. Tolkien
Now onto the science...
This week I'm listening to:
Abracadabra - Lady Gaga
And reading:
The Lord of the Rings - J.R.R. Tolkien
Now onto the science...
Reposted by ross
Excited to share this @nature.com interview about the current state of synthetic genomics.
Our work on the 57-codon E.coli genome shows that while biological complexity continues to surprise us, advanced omics & massively parallel assays now enable genome engineering & design at unprecedented scale
Our work on the 57-codon E.coli genome shows that while biological complexity continues to surprise us, advanced omics & massively parallel assays now enable genome engineering & design at unprecedented scale
February 18, 2025 at 2:14 PM
Excited to share this @nature.com interview about the current state of synthetic genomics.
Our work on the 57-codon E.coli genome shows that while biological complexity continues to surprise us, advanced omics & massively parallel assays now enable genome engineering & design at unprecedented scale
Our work on the 57-codon E.coli genome shows that while biological complexity continues to surprise us, advanced omics & massively parallel assays now enable genome engineering & design at unprecedented scale
Time for a synbio round up!
February 10, 2025 at 1:57 PM
Time for a synbio round up!
20 days into Duolingo's Japanese course and the only way it recognizes what I say is for me to speak slowly and dramatically like I'm the villain in an anime.
February 6, 2025 at 3:25 PM
20 days into Duolingo's Japanese course and the only way it recognizes what I say is for me to speak slowly and dramatically like I'm the villain in an anime.
Let's start the week with some synbio!
January 27, 2025 at 10:26 AM
Let's start the week with some synbio!
Reposted by ross
Yang et al. show how active learning plus directed evolution boosts enzyme performance, capturing epistatic effects and avoiding local maxima to deliver higher yields and selectivity than traditional approaches. www.nature.com/articles/s41...
Active learning-assisted directed evolution - Nature Communications
Directed evolution is a powerful method to optimize protein fitness. Here, authors develop an active learning workflow using machine learning to more efficiently explore the design space of proteins.
www.nature.com
January 17, 2025 at 3:04 PM
Yang et al. show how active learning plus directed evolution boosts enzyme performance, capturing epistatic effects and avoiding local maxima to deliver higher yields and selectivity than traditional approaches. www.nature.com/articles/s41...
So what cool synbio has been published in @naturecomms.bsky.social in the last week? Let's have a look!(oh lookie, the journal is now on BlueSky!)
January 20, 2025 at 1:15 PM
So what cool synbio has been published in @naturecomms.bsky.social in the last week? Let's have a look!(oh lookie, the journal is now on BlueSky!)
Welcome (a bit belatedly) to 2025! Let's see what synbio has been published at Nature Comms so far this year
January 10, 2025 at 10:26 AM
Welcome (a bit belatedly) to 2025! Let's see what synbio has been published at Nature Comms so far this year
Hello from Ghent, where I will be attending Next-Generation Synthetic Biology this week. Looking forward to some great science (and some Belgian delicacies as well)
December 9, 2024 at 1:03 PM
Hello from Ghent, where I will be attending Next-Generation Synthetic Biology this week. Looking forward to some great science (and some Belgian delicacies as well)
Time for a Friday Roundup! (i've missed these 😀)
This week I've been
Watching: Arcane - League of Legends
Reading - A City on Mars (by Kelly Weinersmith and Zach Weinersmith)
Listening: From Zero (Linkin Park)
Plus I have some science for y'all
This week I've been
Watching: Arcane - League of Legends
Reading - A City on Mars (by Kelly Weinersmith and Zach Weinersmith)
Listening: From Zero (Linkin Park)
Plus I have some science for y'all
November 29, 2024 at 11:01 AM
Time for a Friday Roundup! (i've missed these 😀)
This week I've been
Watching: Arcane - League of Legends
Reading - A City on Mars (by Kelly Weinersmith and Zach Weinersmith)
Listening: From Zero (Linkin Park)
Plus I have some science for y'all
This week I've been
Watching: Arcane - League of Legends
Reading - A City on Mars (by Kelly Weinersmith and Zach Weinersmith)
Listening: From Zero (Linkin Park)
Plus I have some science for y'all
Gonna grab a cup of green tea and follow all the live updates from #SBUK24. This definitely feels like the old days of Twitter and I'm loving it.
November 27, 2024 at 11:46 AM
Gonna grab a cup of green tea and follow all the live updates from #SBUK24. This definitely feels like the old days of Twitter and I'm loving it.
The new Linkin Park album is very much powering my day today
a cartoon character is playing a red guitar
Alt: Otto from the Simpsons is playing a mad riff to the enjoyment of the children
media.tenor.com
November 26, 2024 at 9:32 AM
The new Linkin Park album is very much powering my day today
I'll be attending Next-Generation Synthetic Biology in Ghent next month, who can I hope to bump into there?
www.vibconferences.be/events/next-...
www.vibconferences.be/events/next-...
Next-Generation Synthetic Biology (5th edition)
10-11 December 2024, Ghent, Belgium A VIB Tools and Technologies conference
www.vibconferences.be
November 19, 2024 at 2:09 PM
I'll be attending Next-Generation Synthetic Biology in Ghent next month, who can I hope to bump into there?
www.vibconferences.be/events/next-...
www.vibconferences.be/events/next-...
Let's get this started with some recent #synbio papers. Starting off with one I was the editor for:
Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit
www.nature.com/articles/s41...
Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit
www.nature.com/articles/s41...
Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit - Nature Communications
A major goal in synthetic development is to build gene regulatory circuits that control patterning. Here the authors discover that elevated cell density dampens SynNotch signaling, enabling the design...
www.nature.com
November 19, 2024 at 1:23 PM
Let's get this started with some recent #synbio papers. Starting off with one I was the editor for:
Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit
www.nature.com/articles/s41...
Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit
www.nature.com/articles/s41...
Opening post let's set up the vibe of this place:
November 19, 2024 at 11:55 AM
Opening post let's set up the vibe of this place: