Leah Roe
@roeleah.bsky.social
Chemical biologist. Protein editing. Dog mom and nature enthusiast.
Reposted by Leah Roe
✨ New paper in Science: An archaeal genetic code with all TAG codons as pyrrolysine.
www.science.org/doi/10.1126/...
A collaboration with @innovativegenomics.bsky.social
Congrats to the Banfield lab, @roeleah.bsky.social , @nxhamlish.bsky.social , and Alanna!
#NSFfunded
www.science.org/doi/10.1126/...
A collaboration with @innovativegenomics.bsky.social
Congrats to the Banfield lab, @roeleah.bsky.social , @nxhamlish.bsky.social , and Alanna!
#NSFfunded
An archaeal genetic code with all TAG codons as pyrrolysine
Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...
www.science.org
November 20, 2025 at 8:19 PM
✨ New paper in Science: An archaeal genetic code with all TAG codons as pyrrolysine.
www.science.org/doi/10.1126/...
A collaboration with @innovativegenomics.bsky.social
Congrats to the Banfield lab, @roeleah.bsky.social , @nxhamlish.bsky.social , and Alanna!
#NSFfunded
www.science.org/doi/10.1126/...
A collaboration with @innovativegenomics.bsky.social
Congrats to the Banfield lab, @roeleah.bsky.social , @nxhamlish.bsky.social , and Alanna!
#NSFfunded
Reposted by Leah Roe
✨New in Nat Chem Biol: Site-selective protein editing by backbone extension acyl rearrangements
bit.ly/4oKQ251
Congrats @roeleah.bsky.social, Izzi, Carly, Taylor, Bhavana, @nxhamlish.bsky.social, Arjun, Diondra, Zhongqi, @achemsynbio.bsky.social, Matt, Scott, Alanna, and collaborators!
#NSFfunded
bit.ly/4oKQ251
Congrats @roeleah.bsky.social, Izzi, Carly, Taylor, Bhavana, @nxhamlish.bsky.social, Arjun, Diondra, Zhongqi, @achemsynbio.bsky.social, Matt, Scott, Alanna, and collaborators!
#NSFfunded
Site-selective protein editing by backbone extension acyl rearrangements - Nature Chemical Biology
A post-translational backbone extension acyl rearrangement (BEAR) reaction has now been developed that converts a ribosomal protein product into a new product containing a β-peptide, γ-peptide or δ-pe...
www.nature.com
August 21, 2025 at 7:15 PM
✨New in Nat Chem Biol: Site-selective protein editing by backbone extension acyl rearrangements
bit.ly/4oKQ251
Congrats @roeleah.bsky.social, Izzi, Carly, Taylor, Bhavana, @nxhamlish.bsky.social, Arjun, Diondra, Zhongqi, @achemsynbio.bsky.social, Matt, Scott, Alanna, and collaborators!
#NSFfunded
bit.ly/4oKQ251
Congrats @roeleah.bsky.social, Izzi, Carly, Taylor, Bhavana, @nxhamlish.bsky.social, Arjun, Diondra, Zhongqi, @achemsynbio.bsky.social, Matt, Scott, Alanna, and collaborators!
#NSFfunded
Reposted by Leah Roe
A post-translational backbone extension acyl rearrangement (BEAR) reaction has now been developed that converts a ribosomal protein product into a new product containing a β-, γ-, or δ-peptide backbone
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Site-selective protein editing by backbone extension acyl rearrangements - Nature Chemical Biology
A post-translational backbone extension acyl rearrangement (BEAR) reaction has now been developed that converts a ribosomal protein product into a new product containing a β-peptide, γ-peptide or δ-pe...
www.nature.com
August 21, 2025 at 4:34 PM
A post-translational backbone extension acyl rearrangement (BEAR) reaction has now been developed that converts a ribosomal protein product into a new product containing a β-, γ-, or δ-peptide backbone
www.nature.com/articles/s41...
www.nature.com/articles/s41...
I created a protein backbone editing method and named it after my alma mater (x2)! Out now in Nature ChemBio, we show the first examples of a β2-, γ-, and δ-amino acid encoded into full length proteins expressed in cells. www.nature.com/articles/s41...
Site-selective protein editing by backbone extension acyl rearrangements - Nature Chemical Biology
A post-translational backbone extension acyl rearrangement (BEAR) reaction has now been developed that converts a ribosomal protein product into a new product containing a β-peptide, γ-peptide or δ-pe...
www.nature.com
August 21, 2025 at 4:22 PM
I created a protein backbone editing method and named it after my alma mater (x2)! Out now in Nature ChemBio, we show the first examples of a β2-, γ-, and δ-amino acid encoded into full length proteins expressed in cells. www.nature.com/articles/s41...
Reposted by Leah Roe
✨ New from C-GEM:
High yield, low magnesium flexizyme reactions in a water-ice eutectic phase 💧🧊
Congrats to Josh, Jose, Mace, Evan, Angelin, Isaac, Alanna, Aaron, and Kate! #NSFfunded #synbio
www.biorxiv.org/content/10.1...
High yield, low magnesium flexizyme reactions in a water-ice eutectic phase 💧🧊
Congrats to Josh, Jose, Mace, Evan, Angelin, Isaac, Alanna, Aaron, and Kate! #NSFfunded #synbio
www.biorxiv.org/content/10.1...
High yield, low magnesium flexizyme reactions in a water-ice eutectic phase
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
December 4, 2023 at 9:10 PM
✨ New from C-GEM:
High yield, low magnesium flexizyme reactions in a water-ice eutectic phase 💧🧊
Congrats to Josh, Jose, Mace, Evan, Angelin, Isaac, Alanna, Aaron, and Kate! #NSFfunded #synbio
www.biorxiv.org/content/10.1...
High yield, low magnesium flexizyme reactions in a water-ice eutectic phase 💧🧊
Congrats to Josh, Jose, Mace, Evan, Angelin, Isaac, Alanna, Aaron, and Kate! #NSFfunded #synbio
www.biorxiv.org/content/10.1...