Romain Lacombe
@rlacombe.bsky.social
AI/ML⚡️& ChemE 🧪 @ Stanford.
Past: founder Plume Labs (acquired by AccuWeather).
Don’t be fooled by the tweets that I’ve got
I’m still I’m still @rlacombe on X (and here).
-> https://romainlacombe.com
Past: founder Plume Labs (acquired by AccuWeather).
Don’t be fooled by the tweets that I’ve got
I’m still I’m still @rlacombe on X (and here).
-> https://romainlacombe.com
Excited to speak at the
@stanforddata.bsky.social Sustainability Data Science conference today!
I’ll be presenting ClimateX, our work on LLM confidence calibration in the climate science domain.
📄 Paper: arxiv.org/abs/2311.17107
💻 Code: github.com/rlacombe/Cli...
@stanforddata.bsky.social Sustainability Data Science conference today!
I’ll be presenting ClimateX, our work on LLM confidence calibration in the climate science domain.
📄 Paper: arxiv.org/abs/2311.17107
💻 Code: github.com/rlacombe/Cli...
April 10, 2025 at 4:27 PM
Excited to speak at the
@stanforddata.bsky.social Sustainability Data Science conference today!
I’ll be presenting ClimateX, our work on LLM confidence calibration in the climate science domain.
📄 Paper: arxiv.org/abs/2311.17107
💻 Code: github.com/rlacombe/Cli...
@stanforddata.bsky.social Sustainability Data Science conference today!
I’ll be presenting ClimateX, our work on LLM confidence calibration in the climate science domain.
📄 Paper: arxiv.org/abs/2311.17107
💻 Code: github.com/rlacombe/Cli...
Poster time! Fantastic workshop on experimental design in AI for Science today.
Paper: arxiv.org/abs/2503.17368
Workshop: edai4science.github.io
Paper: arxiv.org/abs/2503.17368
Workshop: edai4science.github.io
April 4, 2025 at 5:31 AM
Poster time! Fantastic workshop on experimental design in AI for Science today.
Paper: arxiv.org/abs/2503.17368
Workshop: edai4science.github.io
Paper: arxiv.org/abs/2503.17368
Workshop: edai4science.github.io
Nobel laureate talk time!
With David Baker at the Stanford experimental design in AI for Science today.
With David Baker at the Stanford experimental design in AI for Science today.
April 3, 2025 at 8:31 PM
Nobel laureate talk time!
With David Baker at the Stanford experimental design in AI for Science today.
With David Baker at the Stanford experimental design in AI for Science today.
🔔🔔 New bioML paper alert! 🔔🔔
We evaluate evolutionary protein structure prediction models using the geometric structure of non-canonical crosslinks from a rare class of post-translationally modified peptides.
A thread. 🧵
We evaluate evolutionary protein structure prediction models using the geometric structure of non-canonical crosslinks from a rare class of post-translationally modified peptides.
A thread. 🧵
March 27, 2025 at 8:18 PM
🔔🔔 New bioML paper alert! 🔔🔔
We evaluate evolutionary protein structure prediction models using the geometric structure of non-canonical crosslinks from a rare class of post-translationally modified peptides.
A thread. 🧵
We evaluate evolutionary protein structure prediction models using the geometric structure of non-canonical crosslinks from a rare class of post-translationally modified peptides.
A thread. 🧵
"But you're so much more handsome than that!"
– my beloved wife, when shown a Ghiblified selfie of ourselves.
Right answer!! I'm swooning! 🥰🥰🥰
– my beloved wife, when shown a Ghiblified selfie of ourselves.
Right answer!! I'm swooning! 🥰🥰🥰
March 27, 2025 at 6:39 PM
"But you're so much more handsome than that!"
– my beloved wife, when shown a Ghiblified selfie of ourselves.
Right answer!! I'm swooning! 🥰🥰🥰
– my beloved wife, when shown a Ghiblified selfie of ourselves.
Right answer!! I'm swooning! 🥰🥰🥰
This is much deeper than it sounds at first. Absolute nugget of wisdom.
Follow your own path. It may take longer to get to where you are going, but you will be sure that it really is *you* who gets there, and not someone you don't recognize.
March 25, 2025 at 5:51 PM
This is much deeper than it sounds at first. Absolute nugget of wisdom.
This is an excellent talk by @francesarnold.bsky.social at ACS this week. Worth a read!
cen.acs.org/people/award...
cen.acs.org/people/award...
Priestley Medal address 2025: A random (mostly) uphill walk
A version of this essay will be presented at the American Chemical Society Spring 2025 meeting by 2025 Priestley Medal winner Frances H. Arnold, Linus Pauling Professor of Chemical Engineering, Bioeng...
cen.acs.org
March 23, 2025 at 7:26 PM
This is an excellent talk by @francesarnold.bsky.social at ACS this week. Worth a read!
cen.acs.org/people/award...
cen.acs.org/people/award...
LLMs are Farenheit 451 for digitized human knowledge.
There’s something comforting knowing that the ghost of every written word will live on, for as long as we can preserve open weights, and the GPUs to bring them to life.
There’s something comforting knowing that the ghost of every written word will live on, for as long as we can preserve open weights, and the GPUs to bring them to life.
February 22, 2025 at 7:39 AM
LLMs are Farenheit 451 for digitized human knowledge.
There’s something comforting knowing that the ghost of every written word will live on, for as long as we can preserve open weights, and the GPUs to bring them to life.
There’s something comforting knowing that the ghost of every written word will live on, for as long as we can preserve open weights, and the GPUs to bring them to life.
Chemical engineering rules everything around us. ⚗️
AI 🤖, bio 🧬, chips 💻, energy 🔋, fertilizers 🚜, materials ⛏️, space 🛰️ ...
All the technologies shaping the world sit downstream from chemistry fundamentals. 👩🔬
Hold on to your periodic table and let's go! 🚀
AI 🤖, bio 🧬, chips 💻, energy 🔋, fertilizers 🚜, materials ⛏️, space 🛰️ ...
All the technologies shaping the world sit downstream from chemistry fundamentals. 👩🔬
Hold on to your periodic table and let's go! 🚀
Chemical engineering is the most fascinating field because mass transfers govern everything around us:
🦠 our cells are networks of enzymes
🩸 our body is a system of systems
🔋 our economy a flow of mass/energy
🌎 our planet a giant C, N, O cycle
🪐 thermo and kinetics rule the universe
What else?
🦠 our cells are networks of enzymes
🩸 our body is a system of systems
🔋 our economy a flow of mass/energy
🌎 our planet a giant C, N, O cycle
🪐 thermo and kinetics rule the universe
What else?
January 4, 2025 at 3:06 AM
Chemical engineering rules everything around us. ⚗️
AI 🤖, bio 🧬, chips 💻, energy 🔋, fertilizers 🚜, materials ⛏️, space 🛰️ ...
All the technologies shaping the world sit downstream from chemistry fundamentals. 👩🔬
Hold on to your periodic table and let's go! 🚀
AI 🤖, bio 🧬, chips 💻, energy 🔋, fertilizers 🚜, materials ⛏️, space 🛰️ ...
All the technologies shaping the world sit downstream from chemistry fundamentals. 👩🔬
Hold on to your periodic table and let's go! 🚀
Few things are more heart wrenching than a walk by a wild, pristine, remote beach at the confines of civilization…
…only to find billions of tiny speckles of microplastics all over the sand, which we *know* will end up in our bodies by way of the food chain.
Very sad.
…only to find billions of tiny speckles of microplastics all over the sand, which we *know* will end up in our bodies by way of the food chain.
Very sad.
December 23, 2024 at 1:59 AM
Few things are more heart wrenching than a walk by a wild, pristine, remote beach at the confines of civilization…
…only to find billions of tiny speckles of microplastics all over the sand, which we *know* will end up in our bodies by way of the food chain.
Very sad.
…only to find billions of tiny speckles of microplastics all over the sand, which we *know* will end up in our bodies by way of the food chain.
Very sad.
1 failure per 1000 GPU•days is the going hardware MTF rate for large training runs these days.
#NeurIPS2024
#NeurIPS2024
December 12, 2024 at 12:50 AM
1 failure per 1000 GPU•days is the going hardware MTF rate for large training runs these days.
#NeurIPS2024
#NeurIPS2024
Craziest talk of the day so far: you can recognize which room someone stands in with embeddings of firing rate maps of their place cells neurons!
#NeurIPS2024
#NeurIPS2024
December 11, 2024 at 6:53 PM
Craziest talk of the day so far: you can recognize which room someone stands in with embeddings of firing rate maps of their place cells neurons!
#NeurIPS2024
#NeurIPS2024
Deep learning is chemical engineering for information: layers are process units, diffusion is transport, entropy is the loss function…
Don’t believe me? Then why is the NeurIPS opening talk literally starting with the Haber Bosch process!?
Don’t believe me? Then why is the NeurIPS opening talk literally starting with the Haber Bosch process!?
December 11, 2024 at 6:46 PM
Deep learning is chemical engineering for information: layers are process units, diffusion is transport, entropy is the loss function…
Don’t believe me? Then why is the NeurIPS opening talk literally starting with the Haber Bosch process!?
Don’t believe me? Then why is the NeurIPS opening talk literally starting with the Haber Bosch process!?
Made it to #NeurIPS2024!
Here until Sunday, ping me for coffee, a walk and talk, or some Tim Hortons maple glazed donuts! 🇨🇦
Here until Sunday, ping me for coffee, a walk and talk, or some Tim Hortons maple glazed donuts! 🇨🇦
December 11, 2024 at 3:43 AM
Made it to #NeurIPS2024!
Here until Sunday, ping me for coffee, a walk and talk, or some Tim Hortons maple glazed donuts! 🇨🇦
Here until Sunday, ping me for coffee, a walk and talk, or some Tim Hortons maple glazed donuts! 🇨🇦
I used to add little incandescent light bulbs in my notes, for highlights.💡
But it’s time to decarbonize. 🔋
So now I add little LEDs! ⚡️
But it’s time to decarbonize. 🔋
So now I add little LEDs! ⚡️
December 8, 2024 at 11:44 PM
I used to add little incandescent light bulbs in my notes, for highlights.💡
But it’s time to decarbonize. 🔋
So now I add little LEDs! ⚡️
But it’s time to decarbonize. 🔋
So now I add little LEDs! ⚡️
We can just fix things.
December 3, 2024 at 5:49 AM
We can just fix things.
Reposted by Romain Lacombe
An analogy of the differences between bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomics
#multiomics2024 10/
#multiomics2024 10/
December 1, 2024 at 2:20 AM
An analogy of the differences between bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomics
#multiomics2024 10/
#multiomics2024 10/
Air pollution makes you dumb.
iopscience.iop.org/article/10.1...
iopscience.iop.org/article/10.1...
December 2, 2024 at 6:09 AM
Air pollution makes you dumb.
iopscience.iop.org/article/10.1...
iopscience.iop.org/article/10.1...
Engineering is the ultimate LEGO set.
Piece some unit processes together, add sensors and a PCB to control them, break a few molecular bonds and train a neural net to run the whole thing, and don’t forget your economics so you can keep going.
Is anything more fun than this!? 😀
Piece some unit processes together, add sensors and a PCB to control them, break a few molecular bonds and train a neural net to run the whole thing, and don’t forget your economics so you can keep going.
Is anything more fun than this!? 😀
December 1, 2024 at 10:19 PM
Engineering is the ultimate LEGO set.
Piece some unit processes together, add sensors and a PCB to control them, break a few molecular bonds and train a neural net to run the whole thing, and don’t forget your economics so you can keep going.
Is anything more fun than this!? 😀
Piece some unit processes together, add sensors and a PCB to control them, break a few molecular bonds and train a neural net to run the whole thing, and don’t forget your economics so you can keep going.
Is anything more fun than this!? 😀
Kim Stanley Robinson's "Ministry for the Future" is looking more prescient every day.
www.nytimes.com/2024/11/28/c...
www.nytimes.com/2024/11/28/c...
The U.S. Is Building an Early Warning System to Detect Geoengineering (Gift Article)
Balloon launches from around the world are part of a new kind of global alarm system: One that can detect if another country tries to dim the sun.
www.nytimes.com
December 1, 2024 at 8:03 AM
Kim Stanley Robinson's "Ministry for the Future" is looking more prescient every day.
www.nytimes.com/2024/11/28/c...
www.nytimes.com/2024/11/28/c...
Causality is correlation with a story.
Change my mind.
Change my mind.
November 30, 2024 at 8:37 PM
Causality is correlation with a story.
Change my mind.
Change my mind.
Reposted by Romain Lacombe
This feels likes it pulled right of the Ministry for the Future by Kim Stanley Robinson
#climatechange #greenhousegas
#climatechange #greenhousegas
The U.S. Is Building an Early Warning System to Detect Geoengineering
Balloon launches from around the world are part of a new kind of global alarm system: One that can detect if another country tries to dim the sun.
www.nytimes.com
November 29, 2024 at 5:16 AM
This feels likes it pulled right of the Ministry for the Future by Kim Stanley Robinson
#climatechange #greenhousegas
#climatechange #greenhousegas
Yesterday's heavy fog lifted through the night, and it's a beautiful sunny morning in California. 🌴🇺🇸
Happy Thanksgiving everyone! 🦃🍠🥧🙏❤️
Happy Thanksgiving everyone! 🦃🍠🥧🙏❤️
November 28, 2024 at 6:40 PM
Yesterday's heavy fog lifted through the night, and it's a beautiful sunny morning in California. 🌴🇺🇸
Happy Thanksgiving everyone! 🦃🍠🥧🙏❤️
Happy Thanksgiving everyone! 🦃🍠🥧🙏❤️
Reposted by Romain Lacombe
Happy Chompsgiving!
November 28, 2024 at 6:39 PM
Happy Chompsgiving!
"- Please generate a beautiful picture of a strange attractor.
- Here's the visual representation of a strange attractor, blending intricate and dynamic patterns with a cosmic aesthetic. Let me know if you'd like any adjustments!"
What do y'all think about ChatGPT's chaos theory art skills?
- Here's the visual representation of a strange attractor, blending intricate and dynamic patterns with a cosmic aesthetic. Let me know if you'd like any adjustments!"
What do y'all think about ChatGPT's chaos theory art skills?
November 27, 2024 at 8:08 PM
"- Please generate a beautiful picture of a strange attractor.
- Here's the visual representation of a strange attractor, blending intricate and dynamic patterns with a cosmic aesthetic. Let me know if you'd like any adjustments!"
What do y'all think about ChatGPT's chaos theory art skills?
- Here's the visual representation of a strange attractor, blending intricate and dynamic patterns with a cosmic aesthetic. Let me know if you'd like any adjustments!"
What do y'all think about ChatGPT's chaos theory art skills?