Edis
@reelikklemind.bsky.social
An extremist. An aesthetic voyager. We create our own reality through our personality, and learning is at the heart of intelligence.
Reposted by Edis
New Kimi!!!
This one also supports images (finally) and has this curious thing called agent swarm
This one also supports images (finally) and has this curious thing called agent swarm
January 27, 2026 at 12:37 PM
New Kimi!!!
This one also supports images (finally) and has this curious thing called agent swarm
This one also supports images (finally) and has this curious thing called agent swarm
Reposted by Edis
A tough paper to unpack for non-scientists, but worth it.
We have these amazing new cancer drugs called "checkpoint inhibitors" that block the ability some tumors have to "turn off" immune cells.
The result: a potent cancer-killing immune response.
But they only work in 20-30% of cancer patients.
We have these amazing new cancer drugs called "checkpoint inhibitors" that block the ability some tumors have to "turn off" immune cells.
The result: a potent cancer-killing immune response.
But they only work in 20-30% of cancer patients.
Nature research paper: Microbiota-induced T cell plasticity enables immune-mediated tumour control
go.nature.com/4qMqEwJ
go.nature.com/4qMqEwJ
Microbiota-induced T cell plasticity enables immune-mediated tumour control - Nature
Molecular mimicry between a gut commensal and a tumour antigen forms part of an important mechanistic framework that can boost the efficacy of immune checkpoint blockade therapy and restrain tumour growth.
go.nature.com
January 21, 2026 at 3:42 PM
A tough paper to unpack for non-scientists, but worth it.
We have these amazing new cancer drugs called "checkpoint inhibitors" that block the ability some tumors have to "turn off" immune cells.
The result: a potent cancer-killing immune response.
But they only work in 20-30% of cancer patients.
We have these amazing new cancer drugs called "checkpoint inhibitors" that block the ability some tumors have to "turn off" immune cells.
The result: a potent cancer-killing immune response.
But they only work in 20-30% of cancer patients.
Professor Freeman Dyson on the PhD system:
“The PhD system is an abomination...it has ruined many lives” 2016
“The PhD system is an abomination...it has ruined many lives” 2016
November 24, 2025 at 12:30 PM
Professor Freeman Dyson on the PhD system:
“The PhD system is an abomination...it has ruined many lives” 2016
“The PhD system is an abomination...it has ruined many lives” 2016
The Mindset Mistake I Made Writing My Last Book Review open.substack.com/pub/tmfnk/p/...
The Mindset Mistake I Made Writing My Last Book Review
I just finished a book review that taught me more than the book itself.
open.substack.com
November 5, 2025 at 11:19 AM
The Mindset Mistake I Made Writing My Last Book Review open.substack.com/pub/tmfnk/p/...
Harness your mind to forge a better world.
November 4, 2025 at 9:50 AM
Harness your mind to forge a better world.
People easily sympathize with your failures. They don’t bruise egos.
But your successes? They rattle those who build self-worth on superiority.
But your successes? They rattle those who build self-worth on superiority.
November 4, 2025 at 9:28 AM
People easily sympathize with your failures. They don’t bruise egos.
But your successes? They rattle those who build self-worth on superiority.
But your successes? They rattle those who build self-worth on superiority.
many companies miss out on growth by prioritizing fixed skillsets over learning mindsets.
November 4, 2025 at 8:45 AM
many companies miss out on growth by prioritizing fixed skillsets over learning mindsets.
A single quote holds massive power: "When you enter a mindset, you enter a new world." -Carol S. Dweck.
Your mindset is your operating system. Upgrade it, and your reality changes. Simple as.
Your mindset is your operating system. Upgrade it, and your reality changes. Simple as.
November 3, 2025 at 8:23 AM
A single quote holds massive power: "When you enter a mindset, you enter a new world." -Carol S. Dweck.
Your mindset is your operating system. Upgrade it, and your reality changes. Simple as.
Your mindset is your operating system. Upgrade it, and your reality changes. Simple as.
Many people appear impressive on the surface, but their internal stability is questionable.
November 1, 2025 at 9:19 PM
Many people appear impressive on the surface, but their internal stability is questionable.
Not everyone has reliable internet. I turned my blog into a PWA; read more about it here: www.tmfnk.com/use/tutorial...
Convert Webpage to Progressive Web App (PWA)
Complete guide to transforming your Hugo website into a Progressive Web App with offline functionality, installability, and native app-like experience.
www.tmfnk.com
October 31, 2025 at 12:25 PM
Not everyone has reliable internet. I turned my blog into a PWA; read more about it here: www.tmfnk.com/use/tutorial...
It's unfortunate that standard education omits the valuable skill of financial literacy. 😢
October 30, 2025 at 5:00 PM
It's unfortunate that standard education omits the valuable skill of financial literacy. 😢
Everybody says “I’m a generalist,” which is their way of copping out on being a specialist. But really what you want to be is a polymath, which is a generalist who can pick up every specialty, at least to the 80/20 level, so they can make smart trade-offs. -Naval
October 27, 2025 at 10:05 AM
Everybody says “I’m a generalist,” which is their way of copping out on being a specialist. But really what you want to be is a polymath, which is a generalist who can pick up every specialty, at least to the 80/20 level, so they can make smart trade-offs. -Naval
A taste of freedom can make you unemployable. -Naval Ravikant
October 27, 2025 at 8:35 AM
A taste of freedom can make you unemployable. -Naval Ravikant
Peak scaled.
The long ascent behind me,
I rest on the ridge,
poised for the coming sun.
The long ascent behind me,
I rest on the ridge,
poised for the coming sun.
October 26, 2025 at 8:51 PM
Peak scaled.
The long ascent behind me,
I rest on the ridge,
poised for the coming sun.
The long ascent behind me,
I rest on the ridge,
poised for the coming sun.
I finally made a llms.txt file for my blog (tmfnk.com). It’s in the about section.
TMFNK: The Mind for Navigating Knowledge
TMFNK: Your guide to navigating knowledge. Discover expert insights on books, articles, tools, projects, tutorials, music, podcasts, games, travel, art, movies, and videos. Content that stands the tes...
tmfnk.com
October 15, 2025 at 1:02 PM
I finally made a llms.txt file for my blog (tmfnk.com). It’s in the about section.
"Wall Street is the only place that people ride to in a Rolls-Royce to get advice from those who take the subway." -Warren Buffett
October 9, 2025 at 5:10 PM
"Wall Street is the only place that people ride to in a Rolls-Royce to get advice from those who take the subway." -Warren Buffett
Good content is the best marketing tool.
September 27, 2025 at 10:12 AM
Good content is the best marketing tool.
Perseverance is pursuing a vision through obstacles. Stubbornness is refusing to admit you're already off track.
September 24, 2025 at 5:58 PM
Perseverance is pursuing a vision through obstacles. Stubbornness is refusing to admit you're already off track.
Note to self: Focus on the highest leverage points.
September 23, 2025 at 7:23 AM
Note to self: Focus on the highest leverage points.
Job descriptions are just as "fluffed" as the CVs they attract. 🤔
September 21, 2025 at 6:25 AM
Job descriptions are just as "fluffed" as the CVs they attract. 🤔
Show me an incumbent BIGCO failing to adapt to change, I’ll show you top execs paid huge cash compensation for quarterly and annual goals. -Marc Andreessen
September 21, 2025 at 5:28 AM
Show me an incumbent BIGCO failing to adapt to change, I’ll show you top execs paid huge cash compensation for quarterly and annual goals. -Marc Andreessen
Price and value are not the same thing. One is what you pay, the other is what you get.
#price #value #investing #finance #money
#price #value #investing #finance #money
September 13, 2025 at 3:12 PM
Price and value are not the same thing. One is what you pay, the other is what you get.
#price #value #investing #finance #money
#price #value #investing #finance #money
Opportunity is not evenly distributed.
September 11, 2025 at 7:49 PM
Opportunity is not evenly distributed.
Time is relative, but our lifetime is not.
September 11, 2025 at 9:35 AM
Time is relative, but our lifetime is not.