Raunak Shrestha
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raunakms.bsky.social
Raunak Shrestha
@raunakms.bsky.social
Assistant Professor (incoming) CPDR/USUHS • PhD in Bioinformatics • Data Scientist • Cancer Genomics | MD, USA 🧬💻🔬 🇳🇵 🇨🇦 🇺🇸
WOW! visualizing #nucleosome via cryo-EM
Paper: Direct visualization and tracing of DNA fold in Drosophila embryo doi.org/10.1101/2022...
April 17, 2025 at 9:21 PM
The Genomic Revolution would not have happened without #NIH Funding to support ... #FundScience
April 2, 2025 at 1:45 AM
Reposted by Raunak Shrestha
ANNOUNCEMENT: RFA for 2025 @PCFnews team science Challenge Award Applications, to support investigations of metastatic, lethal #ProstateCancer in 6 specified topic areas.

DEADLINE: May 5, 2025

Apply at: pcf.smartsimple.com

View the RFA: res.cloudinary.com/pcf/images/v...
March 20, 2025 at 4:53 PM
Reposted by Raunak Shrestha
1/ New preprint! 🍳

@elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins!

doi.org/10.1101/2025...
March 18, 2025 at 2:48 PM
Reposted by Raunak Shrestha
Nature research paper: MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC

https://go.nature.com/41IPJwX
MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC - Nature
In a model of pancreatic ductal adenocarcinoma, extrachromosomal DNAs are shown to be a source of high-level focal amplification driving MYC heterogeneity and phenotypic adaptation.
go.nature.com
March 12, 2025 at 7:34 PM