Raquel Rouco, PhD
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raquelrouco.bsky.social
Raquel Rouco, PhD
@raquelrouco.bsky.social
Curiosity-driven researcher 👩🏼‍🔬 Actively seeking to expand my skills. Former member of @guandrey.bsky.social Lab at UNIGE. I love 🧬 #science, #friends, #family & ✈️ #travelling.
Pinned
Did you ever wonder how gene expression, once activated, it's maintained for a precise period of time before being decommissioned? Happy to present the final version of our manuscript on the discovery of regulatory trajectories, just published in Nat. Comms: www.nature.com/articles/s41...
1/14
Reposted by Raquel Rouco, PhD
🧬 We’re #Hiring a #Bioinformatician/ Computational Biologist!
#Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟
📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain)
🕒 Full-time, 3-year position (start March 2026)
📅 Apply by Feb 15, 2026
👉 drive.google.com/file/d/1M8rp...
Job offer 2026.pdf
drive.google.com
January 12, 2026 at 3:57 PM
Reposted by Raquel Rouco, PhD
We are looking for motivated students to apply for the FPU and Junta de Andalucía scholarships to pursue a PhD in 3D genomics and gene regulation in development and disease. If you're interested, please email me: jsantos2@us.es
January 12, 2026 at 1:49 PM
Did you ever wonder how gene expression, once activated, it's maintained for a precise period of time before being decommissioned? Happy to present the final version of our manuscript on the discovery of regulatory trajectories, just published in Nat. Comms: www.nature.com/articles/s41...
1/14
January 12, 2026 at 12:23 PM
Reposted by Raquel Rouco, PhD
We recently reported that promoter competition can contribute to the robust insulation of gene regulatory domains (www.nature.com/articles/s41...).
We now offer a 4-years PhD contract to investigate whether the dirsuption of this regulatory mechanism can lead to congenital defects. More details 👇
November 6, 2025 at 6:37 PM
Reposted by Raquel Rouco, PhD
Our work bridging enhancer-promoter proximity to phenotypic outcomes in vivo is out! Shout out to @olimpiabompadre.bsky.social, to Marie Kmita's lab, and to all the co-authors. www.nature.com/articles/s41...
Liebenberg syndrome severity arises from variations in Pitx1 locus topology and proportion of ectopically transcribing cells - Nature Communications
Here the authors show that reducing enhancer-promoter distance at the Pitx1 locus increases proportion of Pitx1 forelimb expressing cells, worsening skeletal defects in Liebenberg syndrome. They also ...
www.nature.com
July 9, 2025 at 11:58 AM
Reposted by Raquel Rouco, PhD
The final chapter of my Pitx1 adventure is out! 1 simple question:”How do SVs that shorten enhancer-promoter distance affect limb development?” We find the impact on transcription, cell populations, epigenetics, and chromatin structure. A labour of joy with @guandrey.bsky.social & all co-authors.
July 9, 2025 at 12:55 PM