Paul W. Hook
@pwhook.bsky.social
Assistant Editor, The American Journal of Human Genetics @ajhgnews.bsky.social (Posts and views are my own)
Reposted by Paul W. Hook
🎉Spotlight on this year's Outstanding Trainee Publication Award winner Maria Palafox
👉Prioritizing disease-associated missense variants with chemoproteomic-detected amino acids
📄 tinyurl.com/yndpnk2w
📹 tinyurl.com/2b3enw28
👉Prioritizing disease-associated missense variants with chemoproteomic-detected amino acids
📄 tinyurl.com/yndpnk2w
📹 tinyurl.com/2b3enw28
October 23, 2025 at 3:46 PM
🎉Spotlight on this year's Outstanding Trainee Publication Award winner Maria Palafox
👉Prioritizing disease-associated missense variants with chemoproteomic-detected amino acids
📄 tinyurl.com/yndpnk2w
📹 tinyurl.com/2b3enw28
👉Prioritizing disease-associated missense variants with chemoproteomic-detected amino acids
📄 tinyurl.com/yndpnk2w
📹 tinyurl.com/2b3enw28
Reposted by Paul W. Hook
🎉Spotlight on this year's Outstanding Trainee Publication Award winner Yu Fu
👉Role of X chromosome and dosage-compensation mechanisms in complex trait genetics
📄 tinyurl.com/53v4ucpa
📹 tinyurl.com/57ddavd9
👉Role of X chromosome and dosage-compensation mechanisms in complex trait genetics
📄 tinyurl.com/53v4ucpa
📹 tinyurl.com/57ddavd9
October 23, 2025 at 3:48 PM
🎉Spotlight on this year's Outstanding Trainee Publication Award winner Yu Fu
👉Role of X chromosome and dosage-compensation mechanisms in complex trait genetics
📄 tinyurl.com/53v4ucpa
📹 tinyurl.com/57ddavd9
👉Role of X chromosome and dosage-compensation mechanisms in complex trait genetics
📄 tinyurl.com/53v4ucpa
📹 tinyurl.com/57ddavd9
Reposted by Paul W. Hook
Reposted by Paul W. Hook
Today's the final chance to meet the editors of our journals— @ajhgnews.bsky.social & @hggadvances.bsky.social!
🗣️Ask questions, get insights, and build connections that could shape your next publication.
Don’t miss this opportunity before the conference wraps: bit.ly/4nniQQ6 #ASHG25 #ASHG
🗣️Ask questions, get insights, and build connections that could shape your next publication.
Don’t miss this opportunity before the conference wraps: bit.ly/4nniQQ6 #ASHG25 #ASHG
October 17, 2025 at 7:14 PM
Today's the final chance to meet the editors of our journals— @ajhgnews.bsky.social & @hggadvances.bsky.social!
🗣️Ask questions, get insights, and build connections that could shape your next publication.
Don’t miss this opportunity before the conference wraps: bit.ly/4nniQQ6 #ASHG25 #ASHG
🗣️Ask questions, get insights, and build connections that could shape your next publication.
Don’t miss this opportunity before the conference wraps: bit.ly/4nniQQ6 #ASHG25 #ASHG
Reposted by Paul W. Hook
Now: Julian Lucas: Accurate representation of globally diverse human haplotypes in the second release of the human pangenome reference #ASHG25 🧪🧬🖥️
October 17, 2025 at 9:24 PM
Now: Julian Lucas: Accurate representation of globally diverse human haplotypes in the second release of the human pangenome reference #ASHG25 🧪🧬🖥️
Reposted by Paul W. Hook
Day three of #ASHG25 is complete! ✔️
For today’s highlights we:
💡Soaked up insights from today’s scientific sessions
🏅Celebrated the excellence of our outstanding awardees
🔗Connected & collaborated with fellow attendees
See you tomorrow for day four!
For today’s highlights we:
💡Soaked up insights from today’s scientific sessions
🏅Celebrated the excellence of our outstanding awardees
🔗Connected & collaborated with fellow attendees
See you tomorrow for day four!
October 17, 2025 at 12:32 AM
Day three of #ASHG25 is complete! ✔️
For today’s highlights we:
💡Soaked up insights from today’s scientific sessions
🏅Celebrated the excellence of our outstanding awardees
🔗Connected & collaborated with fellow attendees
See you tomorrow for day four!
For today’s highlights we:
💡Soaked up insights from today’s scientific sessions
🏅Celebrated the excellence of our outstanding awardees
🔗Connected & collaborated with fellow attendees
See you tomorrow for day four!
Reposted by Paul W. Hook
To learn more about the science behind this topic, check out these articles from @ajhgnews.bsky.social:
📄 bit.ly/4pXXRVV
📄 bit.ly/4n47Whr
#ASHG
📄 bit.ly/4pXXRVV
📄 bit.ly/4n47Whr
#ASHG
Genome-wide association study of esophageal squamous cell cancer identifies shared and distinct risk variants in African and Chinese populations
Esophageal squamous cell cancer is common in sub-Saharan Africa, but little is known
about the contribution of genetic factors to the development of this cancer. We conducted
a genome-wide search for ...
bit.ly
October 17, 2025 at 1:24 PM
To learn more about the science behind this topic, check out these articles from @ajhgnews.bsky.social:
📄 bit.ly/4pXXRVV
📄 bit.ly/4n47Whr
#ASHG
📄 bit.ly/4pXXRVV
📄 bit.ly/4n47Whr
#ASHG
Reposted by Paul W. Hook
💥#ASHG25 Featured Symposia are here—and they're ending on a high! "Genomes from the Global South" is exploring how ancient and isolated populations with rich histories and cultures are unlocking new genomic discoveries: https://t.co/MaF5CPUtAo #ASHG https://t.co/Jse5NAWelv
October 17, 2025 at 1:24 PM
💥#ASHG25 Featured Symposia are here—and they're ending on a high! "Genomes from the Global South" is exploring how ancient and isolated populations with rich histories and cultures are unlocking new genomic discoveries: https://t.co/MaF5CPUtAo #ASHG https://t.co/Jse5NAWelv
Reposted by Paul W. Hook
You’ve seen the stories. You’ve felt the FOMO. But there’s still time to see #ASHG25 LIVE!
With GenomeCast, you can stream select sessions & join Q&As — all from wherever you are.
🎟️Register now before it’s all over: https://meetings.ashg.org/event/ASHG25/attend/ASHG-2025-GenomeCast
With GenomeCast, you can stream select sessions & join Q&As — all from wherever you are.
🎟️Register now before it’s all over: https://meetings.ashg.org/event/ASHG25/attend/ASHG-2025-GenomeCast
October 17, 2025 at 12:53 PM
You’ve seen the stories. You’ve felt the FOMO. But there’s still time to see #ASHG25 LIVE!
With GenomeCast, you can stream select sessions & join Q&As — all from wherever you are.
🎟️Register now before it’s all over: https://meetings.ashg.org/event/ASHG25/attend/ASHG-2025-GenomeCast
With GenomeCast, you can stream select sessions & join Q&As — all from wherever you are.
🎟️Register now before it’s all over: https://meetings.ashg.org/event/ASHG25/attend/ASHG-2025-GenomeCast
Reposted by Paul W. Hook
Now: Carlos Fernado Buen Abad Najar: Identification of unannotated mRNA isoforms driving gene regulation and disease from large-scale RNA-seq data #ASHG25 🧪🧬🖥️
October 16, 2025 at 9:18 PM
Now: Carlos Fernado Buen Abad Najar: Identification of unannotated mRNA isoforms driving gene regulation and disease from large-scale RNA-seq data #ASHG25 🧪🧬🖥️
Reposted by Paul W. Hook
Now: Erica Vaccari: Reimbursement of germline genetic testing for cancer is impacted by socioeconomic characteristics and insurer type #ASHG25 🧪🧬🖥️
October 16, 2025 at 9:37 PM
Now: Erica Vaccari: Reimbursement of germline genetic testing for cancer is impacted by socioeconomic characteristics and insurer type #ASHG25 🧪🧬🖥️
Reposted by Paul W. Hook
Now: Fan Zhang: Pervasive interaction between HLA, KIR, and TCR for autoimmune diseases in >1 million individuals across diverse populations #ASHG25 🧪🧬🖥️
October 16, 2025 at 9:55 PM
Now: Fan Zhang: Pervasive interaction between HLA, KIR, and TCR for autoimmune diseases in >1 million individuals across diverse populations #ASHG25 🧪🧬🖥️
Reposted by Paul W. Hook
Antonio Adamo, PhD, discusses how supernumerary X chromosomes shape brain organoid architecture and function in a dose-dependent fashion during the #ASHG25 Featured Plenary Abstract Session II
October 16, 2025 at 10:03 PM
Antonio Adamo, PhD, discusses how supernumerary X chromosomes shape brain organoid architecture and function in a dose-dependent fashion during the #ASHG25 Featured Plenary Abstract Session II
Reposted by Paul W. Hook
Meet the assistant editors behind @ajhgnews.bsky.social; @pwhook.bsky.social & @alysonbbarnes.bsky.social!
Find them at booth #854 & get real advice from the people who work behind the scenes to spotlight groundbreaking science. No appointment needed—just bring your questions and curiosity! #ASHG25
Find them at booth #854 & get real advice from the people who work behind the scenes to spotlight groundbreaking science. No appointment needed—just bring your questions and curiosity! #ASHG25
October 16, 2025 at 7:14 PM
Meet the assistant editors behind @ajhgnews.bsky.social; @pwhook.bsky.social & @alysonbbarnes.bsky.social!
Find them at booth #854 & get real advice from the people who work behind the scenes to spotlight groundbreaking science. No appointment needed—just bring your questions and curiosity! #ASHG25
Find them at booth #854 & get real advice from the people who work behind the scenes to spotlight groundbreaking science. No appointment needed—just bring your questions and curiosity! #ASHG25
Reposted by Paul W. Hook
We're starting day three of #ASHG25 strong w/ the morning block of platform sessions! Not sure what to see? Check out this session, 'Human Diversity and Evolution,' highlighting recent progress in the study of ancient DNA and varied human populations: https://t.co/2JPtSIcbcZ https://t.co/RS2i8xLXHl
October 16, 2025 at 12:49 PM
We're starting day three of #ASHG25 strong w/ the morning block of platform sessions! Not sure what to see? Check out this session, 'Human Diversity and Evolution,' highlighting recent progress in the study of ancient DNA and varied human populations: https://t.co/2JPtSIcbcZ https://t.co/RS2i8xLXHl
Reposted by Paul W. Hook
🎖️Congratulations to the ASHG 2025 Lifetime Achievement Awardee Harry (Hal) Dietz, MD, and Mentorship Awardee Carole Ober, PhD! Learn more about the award and their work here: www.ashg.org/membership/a... #ASHG25
October 15, 2025 at 8:49 PM
🎖️Congratulations to the ASHG 2025 Lifetime Achievement Awardee Harry (Hal) Dietz, MD, and Mentorship Awardee Carole Ober, PhD! Learn more about the award and their work here: www.ashg.org/membership/a... #ASHG25
Interested in using finemapping software that can handle the admixed populations Loic Yengo is emphasizing in his Presidential Symposium talk? Check out CARMA-X in @ajhgnews.bsky.social: doi.org/10.1016/j.ajhg…#ASHG2525
https://doi.org/10.1016/j.ajhg…
October 15, 2025 at 9:56 PM
Interested in using finemapping software that can handle the admixed populations Loic Yengo is emphasizing in his Presidential Symposium talk? Check out CARMA-X in @ajhgnews.bsky.social: doi.org/10.1016/j.ajhg…#ASHG2525
Reposted by Paul W. Hook
Day One of #ASHG25 is complete! ✔️
🎙️ASHG President
@sarahtishkoff.bsky.social, kicked off the meeting with a powerful Presidential Address
🌟Connections formed in our networking & pre-meeting events
💡The first plenary abstract session delivered big insights
See you tomorrow for day 2!
🎙️ASHG President
@sarahtishkoff.bsky.social, kicked off the meeting with a powerful Presidential Address
🌟Connections formed in our networking & pre-meeting events
💡The first plenary abstract session delivered big insights
See you tomorrow for day 2!
October 14, 2025 at 11:56 PM
Day One of #ASHG25 is complete! ✔️
🎙️ASHG President
@sarahtishkoff.bsky.social, kicked off the meeting with a powerful Presidential Address
🌟Connections formed in our networking & pre-meeting events
💡The first plenary abstract session delivered big insights
See you tomorrow for day 2!
🎙️ASHG President
@sarahtishkoff.bsky.social, kicked off the meeting with a powerful Presidential Address
🌟Connections formed in our networking & pre-meeting events
💡The first plenary abstract session delivered big insights
See you tomorrow for day 2!
Reposted by Paul W. Hook
“We must keep going with this ability to sample genomes, not just in the convenient places we started out with.” - former Director of the National Institutes of Health, Francis Collins, MD, PhD, during his recognition speech at #ASHG25
October 14, 2025 at 9:11 PM
“We must keep going with this ability to sample genomes, not just in the convenient places we started out with.” - former Director of the National Institutes of Health, Francis Collins, MD, PhD, during his recognition speech at #ASHG25
Reposted by Paul W. Hook
@ajhgnews.bsky.social latest study uncovers regulatory splicing elements & implicates RNA-binding proteins hnRNPF & hnRNPAB in VHL exon 2 regulation. The authors highlight limitations of current prediction tools & provide insights into VHL-related molecular pathogenesis: www.cell.com/ajhg/abstrac...
October 3, 2025 at 1:15 PM
@ajhgnews.bsky.social latest study uncovers regulatory splicing elements & implicates RNA-binding proteins hnRNPF & hnRNPAB in VHL exon 2 regulation. The authors highlight limitations of current prediction tools & provide insights into VHL-related molecular pathogenesis: www.cell.com/ajhg/abstrac...
Reposted by Paul W. Hook
Our October issue is online! Check out the latest human #genetics & #genomics research!
www.cell.com/ajhg/current
www.cell.com/ajhg/current
October 2, 2025 at 4:28 PM
Our October issue is online! Check out the latest human #genetics & #genomics research!
www.cell.com/ajhg/current
www.cell.com/ajhg/current