Paul Sufka MD
@psufka.bsky.social
Great post on Threads about using AI to negotiate a $195k hospital bill down to $33k www.threads.com/@nthmonkey/p...
Matt Rosenberg (@nthmonkey) on Threads
My brother in law died in June. Heart attack. Four hours in the hospital and gone. And then the bills came. He’d let his insurance lapse two months prior. Bills were a few thousand here for the cardio...
www.threads.com
November 3, 2025 at 1:08 AM
Great post on Threads about using AI to negotiate a $195k hospital bill down to $33k www.threads.com/@nthmonkey/p...
Great explanation of AI transformers www.youtube.com/watch?v=JZLZ...
Transformers Explained: The Discovery That Changed AI Forever
YouTube video by Y Combinator
www.youtube.com
October 26, 2025 at 11:47 PM
Great explanation of AI transformers www.youtube.com/watch?v=JZLZ...
Reposted by Paul Sufka MD
2025 ACR Lupus Guideline - Overview presented by Dr. Lisa Sammaritano.
Key take aways:
• HCQ should be standard therapy
• Use GC with precision
• Introduce immunosuppressive therapies early
• Use shared decision-making when considering treatment decisions
#ACR25
Key take aways:
• HCQ should be standard therapy
• Use GC with precision
• Introduce immunosuppressive therapies early
• Use shared decision-making when considering treatment decisions
#ACR25
October 26, 2025 at 2:22 PM
2025 ACR Lupus Guideline - Overview presented by Dr. Lisa Sammaritano.
Key take aways:
• HCQ should be standard therapy
• Use GC with precision
• Introduce immunosuppressive therapies early
• Use shared decision-making when considering treatment decisions
#ACR25
Key take aways:
• HCQ should be standard therapy
• Use GC with precision
• Introduce immunosuppressive therapies early
• Use shared decision-making when considering treatment decisions
#ACR25
Reposted by Paul Sufka MD
A high ANA titer (≥1:640) in individuals without an autoimmune disease was found to be strongly associated with liver-related disorders, including nonalcoholic and alcoholic liver disease
Arthritis Care & Research
doi.org/10.1002/acr....
#Medsky
Arthritis Care & Research
doi.org/10.1002/acr....
#Medsky
October 17, 2025 at 12:43 PM
A high ANA titer (≥1:640) in individuals without an autoimmune disease was found to be strongly associated with liver-related disorders, including nonalcoholic and alcoholic liver disease
Arthritis Care & Research
doi.org/10.1002/acr....
#Medsky
Arthritis Care & Research
doi.org/10.1002/acr....
#Medsky
AI discovers new cancer mechanism. Hopefully the first of many.
October 15, 2025 at 10:03 PM
AI discovers new cancer mechanism. Hopefully the first of many.
Reposted by Paul Sufka MD
Management of SAPHO syndrome remains challenging. A systematic review found patients with SAPHO syndrome receiving JAK inhibitors had significant improvement in clinical symptoms and reduction in markers of inflammation. Time to response varied
ACR Open Rheumatology
doi.org/10.1002/acr2...
#Medsky
ACR Open Rheumatology
doi.org/10.1002/acr2...
#Medsky
JAK Inhibitors for Treatment of SAPHO Syndrome: A Systematic Review of 72 Cases
Objective Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome usually involves bones, joints, and skin. Due to a lack of known pathogenesis and clinical trials, there is no stan...
doi.org
October 14, 2025 at 8:31 PM
Management of SAPHO syndrome remains challenging. A systematic review found patients with SAPHO syndrome receiving JAK inhibitors had significant improvement in clinical symptoms and reduction in markers of inflammation. Time to response varied
ACR Open Rheumatology
doi.org/10.1002/acr2...
#Medsky
ACR Open Rheumatology
doi.org/10.1002/acr2...
#Medsky
Reposted by Paul Sufka MD
Reclaiming care of patients in the age of A.I.
"A.I. will not replace care, rather, it could help us rediscover it."
This week's @thelancet.com editorial
www.thelancet.com/journals/lan...
"A.I. will not replace care, rather, it could help us rediscover it."
This week's @thelancet.com editorial
www.thelancet.com/journals/lan...
October 10, 2025 at 12:08 AM
Reclaiming care of patients in the age of A.I.
"A.I. will not replace care, rather, it could help us rediscover it."
This week's @thelancet.com editorial
www.thelancet.com/journals/lan...
"A.I. will not replace care, rather, it could help us rediscover it."
This week's @thelancet.com editorial
www.thelancet.com/journals/lan...
So much opportunty for medical app development with OpenAI's new Apps SDK. developers.openai.com/apps-sdk
Apps SDK
Learn how to use Apps SDK by OpenAI. Our framework to build apps for ChatGPT.
developers.openai.com
October 7, 2025 at 10:44 PM
So much opportunty for medical app development with OpenAI's new Apps SDK. developers.openai.com/apps-sdk
"general methods that leverage computation are ultimately the most effective, and by a large margin" —The Bitter Lesson, Rich Sutton www.incompleteideas.net/IncIdeas/Bit...
The Bitter Lesson
www.incompleteideas.net
October 6, 2025 at 3:30 PM
"general methods that leverage computation are ultimately the most effective, and by a large margin" —The Bitter Lesson, Rich Sutton www.incompleteideas.net/IncIdeas/Bit...
I can’t suggest using an AI scribe enough.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Ambient AI Scribes to Reduce Administrative Burden and Professional Burnout
This quality improvement study examines whether ambient artificial intelligence (AI) scribes are associated with reductions in clinician administrative burden and burnout.
jamanetwork.com
October 5, 2025 at 1:22 PM
I can’t suggest using an AI scribe enough.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Reposted by Paul Sufka MD
A.I. generated clinic notes from ambient out-patient visits helps clinicians in many ways, across 6 health systems jamanetwork.com/journals/jam...
October 2, 2025 at 5:54 PM
A.I. generated clinic notes from ambient out-patient visits helps clinicians in many ways, across 6 health systems jamanetwork.com/journals/jam...
Reposted by Paul Sufka MD
My latest Substack: As OpenEvidence sprinted past UpToDate to become medicine's best AI-enabled point-of-care tool, I've been waiting for UTD's response. Now it's here, raising fascinating questions about which knowledge base should be our source of truth.
robertwachter.substack.com/p/medicines-...
robertwachter.substack.com/p/medicines-...
Medicine’s AI Knowledge War Heats Up
The Battlegrounds May Surprise You
robertwachter.substack.com
October 1, 2025 at 5:53 PM
My latest Substack: As OpenEvidence sprinted past UpToDate to become medicine's best AI-enabled point-of-care tool, I've been waiting for UTD's response. Now it's here, raising fascinating questions about which knowledge base should be our source of truth.
robertwachter.substack.com/p/medicines-...
robertwachter.substack.com/p/medicines-...
Reposted by Paul Sufka MD
Highlighting some of the many current pitfalls of A.I. in health care
@newyorker.com
@dhruvkhullar.bsky.social
www.newyorker.com/magazine/202...
@newyorker.com
@dhruvkhullar.bsky.social
www.newyorker.com/magazine/202...
If A.I. Can Diagnose Patients, What Are Doctors For?
Large language models are transforming medicine—but the technology comes with side effects.
www.newyorker.com
September 22, 2025 at 2:34 PM
Highlighting some of the many current pitfalls of A.I. in health care
@newyorker.com
@dhruvkhullar.bsky.social
www.newyorker.com/magazine/202...
@newyorker.com
@dhruvkhullar.bsky.social
www.newyorker.com/magazine/202...
Dr. Amanda Ombrello talking about autoinflammatory diseases
September 19, 2025 at 7:36 PM
Dr. Amanda Ombrello talking about autoinflammatory diseases
Always great to hear Dr. Marcela Ferrada speak about relapsing polychondtitis.
September 19, 2025 at 6:08 PM
Always great to hear Dr. Marcela Ferrada speak about relapsing polychondtitis.
Slides and notes for my talk this afternoon: The Current State of AI in Rheumatology — Virginia Society of Rheumatology 2025 Annual Meeting paulsufka.com/ai/
September 19, 2025 at 3:45 PM
Slides and notes for my talk this afternoon: The Current State of AI in Rheumatology — Virginia Society of Rheumatology 2025 Annual Meeting paulsufka.com/ai/
"LLMs have "dead reasoning zones" — areas in their weights where logic doesn't work. Humans have dead knowledge zones (things we don't know), but not dead reasoning zones. Asking questions outside the training distribution is almost like an adversarial attack on the model."
How I got the highest score on ARC-AGI again swapping Python for English
Using Multi-Agent Collaboration with Evolutionary Test-Time Compute
jeremyberman.substack.com
September 17, 2025 at 5:47 PM
"LLMs have "dead reasoning zones" — areas in their weights where logic doesn't work. Humans have dead knowledge zones (things we don't know), but not dead reasoning zones. Asking questions outside the training distribution is almost like an adversarial attack on the model."
Reposted by Paul Sufka MD
Retrospective review of patients with rheumatoid arthritis and BMI≥27 prescribed GLP-1RA (semaglutide or tirzepatide) showed improved disease activity & cardiovascular risk factors vs controls. Nearly one-third of GLP-1RA group discontinued during study period
ACROR
doi.org/10.1002/acr2...
#Medsky
ACROR
doi.org/10.1002/acr2...
#Medsky
Effect of Glucagon‐Like Peptide 1 Receptor Agonists on Patients With Rheumatoid Arthritis
Objective Glucagon-like peptide 1 receptor agonists (GLP-1RAs) are approved for weight loss, diabetes, and cardiovascular risk reduction. Despite widespread use, GLP-1RAs have not been well studied ...
doi.org
September 12, 2025 at 12:33 PM
Retrospective review of patients with rheumatoid arthritis and BMI≥27 prescribed GLP-1RA (semaglutide or tirzepatide) showed improved disease activity & cardiovascular risk factors vs controls. Nearly one-third of GLP-1RA group discontinued during study period
ACROR
doi.org/10.1002/acr2...
#Medsky
ACROR
doi.org/10.1002/acr2...
#Medsky
I started a Github repo for my AI Scribe Template github.com/psufka/AI-Sc...
Feel free to use/modify/share.
Feel free to use/modify/share.
GitHub - psufka/AI-Scribe-Template: Template for rheumatology clinic visits
Template for rheumatology clinic visits. Contribute to psufka/AI-Scribe-Template development by creating an account on GitHub.
github.com
September 10, 2025 at 5:01 PM
I started a Github repo for my AI Scribe Template github.com/psufka/AI-Sc...
Feel free to use/modify/share.
Feel free to use/modify/share.
Nobel Prize winner and Google DeepMind CEO Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games... youtu.be/-HzgcbRXUK8
Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games | Lex Fridman Podcast #475
YouTube video by Lex Fridman
youtu.be
September 9, 2025 at 12:50 AM
Nobel Prize winner and Google DeepMind CEO Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games... youtu.be/-HzgcbRXUK8
The Illusion of Thinking (Apple et al.)
Emergent statistical effect ≠ Thinking
ml-site.cdn-apple.com/papers/the-i...
Emergent statistical effect ≠ Thinking
ml-site.cdn-apple.com/papers/the-i...
September 8, 2025 at 7:47 PM
The Illusion of Thinking (Apple et al.)
Emergent statistical effect ≠ Thinking
ml-site.cdn-apple.com/papers/the-i...
Emergent statistical effect ≠ Thinking
ml-site.cdn-apple.com/papers/the-i...
Understanding why hallucinations happen gives ways to avoid them. I expect this will happen quickly (like everything else in AI).
September 8, 2025 at 1:07 AM
Understanding why hallucinations happen gives ways to avoid them. I expect this will happen quickly (like everything else in AI).