With a growing focus on safer lab practices and sustainability, researchers are rethinking the chemicals they use daily. Traditional protein purification methods often rely on imidazole and nickel-based systems, which come with toxicity risks and environmental concerns.

Cell therapy methods are slow, costly, and inefficient for #rarediseases. The Proteios AptaCapture Platform is here to fix that. By eliminating the need for antibodies & nanobeads, we’re making cell therapy faster, more scalable, and accessible for researchers & clinicians.

For #RareDiseaseDay we’re at the PNRI & Seattle Children's Rare Disease Symposium today, showcasing how Proteios Technology is transforming cell therapy manufacturing for rare diseases. Should be a great event for the Seattle rare disease community! #RareDiseaseDay #Seattle #PNRI

Today is #RareDiseaseDay a time to recognize the 300M+ people worldwide living with rare diseases. Many conditions, like AEC syndrome & rare B-cell cancers, lack effective treatments. Advancing research & innovative therapies is crucial.
#RareDiseaseAwareness #RDD2025 #medsky

Nickel resins are widely used in protein purification, yet they persist in the environment, bioaccumulate in ecosystems, and pose toxicity risks to researchers and aquatic life. Ethanol stabilization adds flammability concerns and increases hazardous waste disposal requirements. #nomorenickel

Nickel resins are common in protein purification, but at what cost?
⚠ Toxicity – Heavy metal exposure harms health & ecosystems.
🔥 Fire Risk – Ethanol-stabilized resins need strict safety measures.
🗑 High Costs – Hazardous waste disposal adds complexity.
Safer alternatives exist ⬇️ #NickelResin 1/n

Here’s what we found:
✔ KRAS, TEV protease, and PFK were purified with 85-95% purity.
✔ Yields reached up to 2mg in a single run.
✔ The workflow avoided toxic reagents and took less than 15 minutes.

The gel tells the story—clear, strong bands for some of the toughest-to-purify proteins!
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KRAS, TEV protease, and T. thermophilus PFK are crucial for advancing research in cancer, molecular biology, and thermophilic bacteria. Low expression levels, solubility issues, and complex workflows make them difficult to purify, so we tested the RapidPro™ Spin Kit to overcome these issues 1/n

✅ Achieved >90% protein purity <30 minutes—directly from crude lysates
✅Gravity columns eliminate the need for pumps or special equipment
✅ Effective for difficult-to-purify proteins, including GFPmut2, mCherry, and MBP, with purities between 80–90%
✅ Hazard-free—no imidazole needed (no toxic waste)

Traditional protein purification is often slow, costly, and complex. At Proteios Technology, we tested the RapidPro™ Gravity Kit to see if it could simplify workflows while maintaining precision. The results? Game-changing.
Learn More: www.proteios.com/proteios-blo...

Traditional protein purification is often slow, costly, and complex. At Proteios Technology, we tested the RapidPro™ Gravity Kit to see if it could simplify workflows while maintaining precision. The results? Game-changing.
Learn More: www.proteios.com/proteios-blo...

New year, new me-thods! 🧪✨ Time to leave inefficient purifications in 2024 where they belong. Here’s to higher yields, cleaner proteins, and fewer lab tantrums in 2025. 💧🔬

Traditional methods for protein purification often require multiple chromatography steps, costly reagents, and specialized equipment. We’ve streamlined this with the RapidPro Gravity™ Column, which leverages the Car9 tag to simplify and enhance protein purification through a gravity flow system.

What’s the most challenging part of your research process? A) Protein purification B) Data analysis C) Grant writing D) Other (tell us below!)

Hey BlueSky! 👋Proteios Technology here! We’re leveraging advances in protein engineering and gene synthesis to offer a brand-new recombinant protein purification method that’s rapid, simple, and safe. 🧪✨
Here is a brief introduction to our recent work! ⬇️ 1/5