Paolo E Porporato
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porpolab.bsky.social
Paolo E Porporato
@porpolab.bsky.social
I am Associate Professor in Experimental Biology at the University of Turin. My laboratory is interested in #cancer #metabolism and #cachexia.
https://www.dbmss.unito.it/do/home.pl/View?doc=/Gruppi_ricerca/Cancer_Metabolism_And_Cachexia.html
Let's Start this 2025 (and this new Social) with a Post :)

Our review on inter-organ crosstalk driving Cancer Cachexia is now available @cp-trendsendomet.bsky.social

Systemic metabolic crosstalk as a driver of cancer cachexia by Wyart et al.

#Research #CancerCachexia #Metabolism #Muscle
authors.elsevier.com
January 7, 2025 at 11:15 AM
Reposted by Paolo E Porporato
#WeekendRead! #MetabolismPower! @fendtlab.bsky.social &co show @ Nature that pulmonary aspartate favors lung metastases via CREB & DOHH dependent hypusination of the alternative translation factor eIF5A, driving TGFb & collagen deposition! www.nature.com/articles/s41...
Aspartate signalling drives lung metastasis via alternative translation - Nature
Aspartate in the tumour environment activates the N-methyl-d-aspartate receptor in cancer cells to induce cellular programmes that increase the aggressiveness of metastasis.
www.nature.com
January 5, 2025 at 3:43 PM