pinaronal
@pinaronal.bsky.social
scientist/assistant prof. in bilkent university mbg, interested in transcriptional regulation and transcription factors. #drosophila #IDRs #evo-devo
Reposted by pinaronal
Latest work out today in @currentbiology.bsky.social
We find the fly development gene bicoid is much older than previously thought (~20 million yrs older!) 🪰🧬
To pinpoint its origins we tackled the Diptera phylogeny, providing some resolution (many open questions remain).
🔗 tinyurl.com/2vyuevpy
We find the fly development gene bicoid is much older than previously thought (~20 million yrs older!) 🪰🧬
To pinpoint its origins we tackled the Diptera phylogeny, providing some resolution (many open questions remain).
🔗 tinyurl.com/2vyuevpy
Revised evolutionary relationships within Brachycera and the early origin of bicoid in flies
Mulhair et al. uncover a functional bicoid in non-cyclorrhaphan flies, pushing the
gene's origin back by ∼20 million years. Reassessing the Diptera phylogeny using the
largest dataset to date permits ...
www.cell.com
October 17, 2025 at 3:14 PM
Latest work out today in @currentbiology.bsky.social
We find the fly development gene bicoid is much older than previously thought (~20 million yrs older!) 🪰🧬
To pinpoint its origins we tackled the Diptera phylogeny, providing some resolution (many open questions remain).
🔗 tinyurl.com/2vyuevpy
We find the fly development gene bicoid is much older than previously thought (~20 million yrs older!) 🪰🧬
To pinpoint its origins we tackled the Diptera phylogeny, providing some resolution (many open questions remain).
🔗 tinyurl.com/2vyuevpy
Reposted by pinaronal
We are recruiting PhD students!
Two days left to apply for the LSI studentships - deadline Nov 26
www.exeter.ac.uk/research/ins...
and a few more for the SWBio studentships - deadline Dec 3
www.swbio.ac.uk/programme/pr...
Please repost or forward to prospective students that might be interested!
Two days left to apply for the LSI studentships - deadline Nov 26
www.exeter.ac.uk/research/ins...
and a few more for the SWBio studentships - deadline Dec 3
www.swbio.ac.uk/programme/pr...
Please repost or forward to prospective students that might be interested!
LSI PhD programme | Living Systems Institute | University of Exeter
www.exeter.ac.uk
November 24, 2025 at 3:19 PM
We are recruiting PhD students!
Two days left to apply for the LSI studentships - deadline Nov 26
www.exeter.ac.uk/research/ins...
and a few more for the SWBio studentships - deadline Dec 3
www.swbio.ac.uk/programme/pr...
Please repost or forward to prospective students that might be interested!
Two days left to apply for the LSI studentships - deadline Nov 26
www.exeter.ac.uk/research/ins...
and a few more for the SWBio studentships - deadline Dec 3
www.swbio.ac.uk/programme/pr...
Please repost or forward to prospective students that might be interested!
Reposted by pinaronal
One month left for early-career researchers to apply for a funded place at our Workshop 'Novelty, Co-option and Divergence During Gene Network Evolution' organised by James Hombría & Antónia Monteiro Deadline 5 Dec.
biologists.com/workshops/ju...
@isabelalmudi.bsky.social @jlopezrios.bsky.social
biologists.com/workshops/ju...
@isabelalmudi.bsky.social @jlopezrios.bsky.social
Novelty, Co-option and Divergence During Gene Network Evolution
Novelty, Co-option and Divergence During Gene Network Evolution Recent studies on the evolution of novel traits provide a window of opportunity to understand how existing gene-regulatory networks (GRN...
biologists.com
November 5, 2025 at 7:31 AM
One month left for early-career researchers to apply for a funded place at our Workshop 'Novelty, Co-option and Divergence During Gene Network Evolution' organised by James Hombría & Antónia Monteiro Deadline 5 Dec.
biologists.com/workshops/ju...
@isabelalmudi.bsky.social @jlopezrios.bsky.social
biologists.com/workshops/ju...
@isabelalmudi.bsky.social @jlopezrios.bsky.social
Reposted by pinaronal
In the most recent episode of the Epigenetics Podcast, we talked with @arnausebe.bsky.social from the @crg.eu in Barcelona about his work on chromatin evolution. #podcast #chromatin #epigenetics
Listen here: www.activemotif.com/podcasts-arn...
Listen here: www.activemotif.com/podcasts-arn...
September 8, 2025 at 7:01 AM
In the most recent episode of the Epigenetics Podcast, we talked with @arnausebe.bsky.social from the @crg.eu in Barcelona about his work on chromatin evolution. #podcast #chromatin #epigenetics
Listen here: www.activemotif.com/podcasts-arn...
Listen here: www.activemotif.com/podcasts-arn...
Reposted by pinaronal
I would not restrict to 'fly research', which may sound little important to the uninformed reader. FlyBase is the most elaborate, detailed and precise model organism data base we have and of use to many far beyond the Drosophila community - whilst being a role model setting helpful standards.
FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research.
By @claudia-lopez.bsky.social
www.thetransmitter.org/community/ha...
By @claudia-lopez.bsky.social
www.thetransmitter.org/community/ha...
Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.
www.thetransmitter.org
August 14, 2025 at 12:02 PM
I would not restrict to 'fly research', which may sound little important to the uninformed reader. FlyBase is the most elaborate, detailed and precise model organism data base we have and of use to many far beyond the Drosophila community - whilst being a role model setting helpful standards.
Reposted by pinaronal
✅Yerinden edilmiş Filistinli anne Samah Matar ve 24 Temmuz 2025'te açlık krizi nedeniyle sığındıkları bir okulda beyin felci hastası ve yetersiz beslenen oğlu Yusuf.
✅27 Mayıs'tan bu yana Gazze'de yiyecek almaya çalışan binden fazla Filistinli İsrail Ordusu tarafından öldürüldü
✅27 Mayıs'tan bu yana Gazze'de yiyecek almaya çalışan binden fazla Filistinli İsrail Ordusu tarafından öldürüldü
July 26, 2025 at 7:49 AM
✅Yerinden edilmiş Filistinli anne Samah Matar ve 24 Temmuz 2025'te açlık krizi nedeniyle sığındıkları bir okulda beyin felci hastası ve yetersiz beslenen oğlu Yusuf.
✅27 Mayıs'tan bu yana Gazze'de yiyecek almaya çalışan binden fazla Filistinli İsrail Ordusu tarafından öldürüldü
✅27 Mayıs'tan bu yana Gazze'de yiyecek almaya çalışan binden fazla Filistinli İsrail Ordusu tarafından öldürüldü
Reposted by pinaronal
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good!
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
AlphaFold - A practical guide
AlphaFold - A practical guide
www.ebi.ac.uk
July 21, 2025 at 3:33 PM
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good!
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
Reposted by pinaronal
🎉 Thrilled to share our new paper in @narjournal.bsky.social!
We uncover how the Hox TF Ultrabithorax controls alternative splicing to shape muscle patterning and homeotic identity 🧬 @igmm-montpel.bsky.social
🔗 doi.org/10.1093/nar/...
We uncover how the Hox TF Ultrabithorax controls alternative splicing to shape muscle patterning and homeotic identity 🧬 @igmm-montpel.bsky.social
🔗 doi.org/10.1093/nar/...
Synergistic DNA and RNA binding of the Hox transcription factor Ultrabithorax coordinates splicing and shapes in vivo homeotic functions
Abstract. The dual interaction of many transcription factors (TFs) with both DNA and RNA is an underexplored issue that could fundamentally reshape our und
doi.org
July 4, 2025 at 5:40 PM
🎉 Thrilled to share our new paper in @narjournal.bsky.social!
We uncover how the Hox TF Ultrabithorax controls alternative splicing to shape muscle patterning and homeotic identity 🧬 @igmm-montpel.bsky.social
🔗 doi.org/10.1093/nar/...
We uncover how the Hox TF Ultrabithorax controls alternative splicing to shape muscle patterning and homeotic identity 🧬 @igmm-montpel.bsky.social
🔗 doi.org/10.1093/nar/...
Reposted by pinaronal
#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 4:15 PM
#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
Reposted by pinaronal
#Zebrafish people, this is our time to shine. Let's help keep an important resource up so we can keep talking shit about flies for many many years
The #Drosophila community can donate to the European side to save FlyBase @flybase.bsky.social at the following link:
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...
June 3, 2025 at 6:30 PM
#Zebrafish people, this is our time to shine. Let's help keep an important resource up so we can keep talking shit about flies for many many years
Reposted by pinaronal
Did you know that FlyBase maintains a page highlighting papers that report useful new techniques, resources, or reagents? Check out our Papers with Technical Advances page (updated monthly): wiki.flybase.org/wiki/FlyBase...
FlyBase:Papers with technical advances - FlyBase Wiki
wiki.flybase.org
November 28, 2023 at 7:00 PM
Did you know that FlyBase maintains a page highlighting papers that report useful new techniques, resources, or reagents? Check out our Papers with Technical Advances page (updated monthly): wiki.flybase.org/wiki/FlyBase...
Reposted by pinaronal
This was fun to write! Always amazed by the complexities of transcriptional regulation. @pinaronal.bsky.social
We did a thing with Rhea Datta @rheadatta.bsky.social, Dilan Akdoğan @dilanakdogan.bsky.social and Beste Tezcan. It got much better than we imagined with the help of the anonymous referees. febs.onlinelibrary.wiley.com/doi/10.1111/...
FEBS Press
Disordered effector domains (EDs) of transcription factors (TFs) play versatile roles in transcriptional regulation. These include mediating protein–protein interactions with protein complexes like, ...
febs.onlinelibrary.wiley.com
February 2, 2025 at 4:01 PM
This was fun to write! Always amazed by the complexities of transcriptional regulation. @pinaronal.bsky.social
We did a thing with Rhea Datta @rheadatta.bsky.social, Dilan Akdoğan @dilanakdogan.bsky.social and Beste Tezcan. It got much better than we imagined with the help of the anonymous referees. febs.onlinelibrary.wiley.com/doi/10.1111/...
FEBS Press
Disordered effector domains (EDs) of transcription factors (TFs) play versatile roles in transcriptional regulation. These include mediating protein–protein interactions with protein complexes like, ...
febs.onlinelibrary.wiley.com
February 2, 2025 at 3:42 PM
We did a thing with Rhea Datta @rheadatta.bsky.social, Dilan Akdoğan @dilanakdogan.bsky.social and Beste Tezcan. It got much better than we imagined with the help of the anonymous referees. febs.onlinelibrary.wiley.com/doi/10.1111/...