Patrick Heizer
@patrickheizer.bsky.social
Biomedical engineer at AstraZeneca, permaculture farmer in Maryland, amateur Camus scholar, Chesapeake Bay watershed supremacy, husband, and father.
TheCounterpoint.substack.com
TheCounterpoint.substack.com
How the periodic table explains the current economy.
My latest, "AI Bubble or Island Of Stability?"
open.substack.com/pub/thecount...
My latest, "AI Bubble or Island Of Stability?"
open.substack.com/pub/thecount...
AI Bubble or Island Of Stability?
How the periodic table explains the current economy.
open.substack.com
October 22, 2025 at 11:07 AM
How the periodic table explains the current economy.
My latest, "AI Bubble or Island Of Stability?"
open.substack.com/pub/thecount...
My latest, "AI Bubble or Island Of Stability?"
open.substack.com/pub/thecount...
North America has the highest quality grasslands and savannas in the entire world.
We could and should be entirely independent from globalized meat production.
Any meat import is a policy error.
We could and should be entirely independent from globalized meat production.
Any meat import is a policy error.
October 20, 2025 at 12:27 PM
North America has the highest quality grasslands and savannas in the entire world.
We could and should be entirely independent from globalized meat production.
Any meat import is a policy error.
We could and should be entirely independent from globalized meat production.
Any meat import is a policy error.
Protesting is all well and good, but if you really want to hurt the current (or any) administration, then stop spending money.
You vote every day with your dollars.
You vote every day with your dollars.
October 18, 2025 at 7:58 PM
Protesting is all well and good, but if you really want to hurt the current (or any) administration, then stop spending money.
You vote every day with your dollars.
You vote every day with your dollars.
Hey Dads, go plant some fruit trees with your children.
You won't regret it.
You won't regret it.
October 18, 2025 at 7:54 PM
Hey Dads, go plant some fruit trees with your children.
You won't regret it.
You won't regret it.
In the 41 House elections since 1944, Republicans have won >50.0% of the total vote four times.
Democrats have done it 24 times, and four times since 2006.
Democrats have done it 24 times, and four times since 2006.
October 17, 2025 at 4:36 PM
In the 41 House elections since 1944, Republicans have won >50.0% of the total vote four times.
Democrats have done it 24 times, and four times since 2006.
Democrats have done it 24 times, and four times since 2006.
The future contains more paths forward than you're imagining.
October 17, 2025 at 11:39 AM
The future contains more paths forward than you're imagining.
"Unlike human cGAS, which inhibits DNA repair by homologous recombination in the nucleus, the naked mole rat enzyme has four amino acid changes that allow it to enhance DNA repair, thus delaying aging and enhancing life span."
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging
Efficient DNA repair might make possible the longevity of naked mole-rats. However, whether they have distinctive mechanisms to optimize functions of DNA repair suppressors is unclear. We find that na...
www.science.org
October 9, 2025 at 8:56 PM
"Unlike human cGAS, which inhibits DNA repair by homologous recombination in the nucleus, the naked mole rat enzyme has four amino acid changes that allow it to enhance DNA repair, thus delaying aging and enhancing life span."
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
One aspect of the crisis of modernity is the decay of our capacities for both punishment and forgiveness.
My latest: thecounterpoint.substack.com/p/we-need-pu...
My latest: thecounterpoint.substack.com/p/we-need-pu...
We Need Punishment; We Need Forgiveness
A diagnosis of modern society
thecounterpoint.substack.com
October 9, 2025 at 10:49 AM
One aspect of the crisis of modernity is the decay of our capacities for both punishment and forgiveness.
My latest: thecounterpoint.substack.com/p/we-need-pu...
My latest: thecounterpoint.substack.com/p/we-need-pu...
Infinite Jest deserves every bit of acclaim it receives, but I wish more people also read The Pale King.
While unfinished, it contains as much genius, heart, and wisdom as Infinite Jest.
While unfinished, it contains as much genius, heart, and wisdom as Infinite Jest.
September 28, 2025 at 4:36 PM
Infinite Jest deserves every bit of acclaim it receives, but I wish more people also read The Pale King.
While unfinished, it contains as much genius, heart, and wisdom as Infinite Jest.
While unfinished, it contains as much genius, heart, and wisdom as Infinite Jest.
My farm's very first pawpaw!!
I'm in a quiet and humble state of shock. I knew that this tree had flowered, but it was the only one, so I'd said, "oh, maybe next year!"
But I was mowing the orchard for the last time this year, and I noticed this single fruit in the mulch.
I'm in a quiet and humble state of shock. I knew that this tree had flowered, but it was the only one, so I'd said, "oh, maybe next year!"
But I was mowing the orchard for the last time this year, and I noticed this single fruit in the mulch.
September 27, 2025 at 3:48 PM
My farm's very first pawpaw!!
I'm in a quiet and humble state of shock. I knew that this tree had flowered, but it was the only one, so I'd said, "oh, maybe next year!"
But I was mowing the orchard for the last time this year, and I noticed this single fruit in the mulch.
I'm in a quiet and humble state of shock. I knew that this tree had flowered, but it was the only one, so I'd said, "oh, maybe next year!"
But I was mowing the orchard for the last time this year, and I noticed this single fruit in the mulch.
Permethrin-treated baby wraps reduce the incidence of malaria by ~50%.
Extraordinary results from a "low-tech" intervention. www.nejm.org/doi/full/10....
Extraordinary results from a "low-tech" intervention. www.nejm.org/doi/full/10....
Permethrin-Treated Baby Wraps for the Prevention of Malaria | NEJM
Malaria remains a major cause of childhood death in sub-Saharan Africa. We leveraged
the traditional practice of mothers carrying children on their backs in cloth wraps
to assess whether treating t...
www.nejm.org
September 25, 2025 at 12:13 PM
Permethrin-treated baby wraps reduce the incidence of malaria by ~50%.
Extraordinary results from a "low-tech" intervention. www.nejm.org/doi/full/10....
Extraordinary results from a "low-tech" intervention. www.nejm.org/doi/full/10....
Please do NOT take either aspirin or ibuprofen (Advil, Motrin, etc.) instead of acetaminophen (Tylenol) during pregnancy without consulting your OBGYN first.
Both inhibit prostaglandin synthesis, an extremely important class of lipid compounds, which could put you or your baby at risk.
Both inhibit prostaglandin synthesis, an extremely important class of lipid compounds, which could put you or your baby at risk.
September 23, 2025 at 2:30 PM
Please do NOT take either aspirin or ibuprofen (Advil, Motrin, etc.) instead of acetaminophen (Tylenol) during pregnancy without consulting your OBGYN first.
Both inhibit prostaglandin synthesis, an extremely important class of lipid compounds, which could put you or your baby at risk.
Both inhibit prostaglandin synthesis, an extremely important class of lipid compounds, which could put you or your baby at risk.
Frederick, MD has one of the nicest downtowns in the US. It's a walkable core overflowing w/ local small businesses, historic buildings, & mature tree canopy.
But it didn't just happen. It took decades of active leadership & community involvement.
This book tells that story.
But it didn't just happen. It took decades of active leadership & community involvement.
This book tells that story.
September 23, 2025 at 2:10 PM
Frederick, MD has one of the nicest downtowns in the US. It's a walkable core overflowing w/ local small businesses, historic buildings, & mature tree canopy.
But it didn't just happen. It took decades of active leadership & community involvement.
This book tells that story.
But it didn't just happen. It took decades of active leadership & community involvement.
This book tells that story.
First, Tylenol is a brand name, not a pharmaceutical. Actimenophen is the more correct word.
Second, women don't take an actimenophen for no reason; they take it because of fever, pain, etc. Without very well-controlled trials, it's impossible to sort out intertwined variables.
Second, women don't take an actimenophen for no reason; they take it because of fever, pain, etc. Without very well-controlled trials, it's impossible to sort out intertwined variables.
REPOSTED: President Donald Trump plans to announce Monday that using Tylenol during pregnancy could contribute to autism risk. Trump will also highlight leucovorin, a cancer and anemia drug, as a potential therapy for people with autism.
www.politico.com/news/2025/09...
www.politico.com/news/2025/09...
Trump administration to link Tylenol use to risk of autism
The president is expected to say that acetaminophen, the most commonly used pain reliever during pregnancy, should only be used for high fevers.
www.politico.com
September 22, 2025 at 8:01 PM
First, Tylenol is a brand name, not a pharmaceutical. Actimenophen is the more correct word.
Second, women don't take an actimenophen for no reason; they take it because of fever, pain, etc. Without very well-controlled trials, it's impossible to sort out intertwined variables.
Second, women don't take an actimenophen for no reason; they take it because of fever, pain, etc. Without very well-controlled trials, it's impossible to sort out intertwined variables.
Erika Kirk forgiving her husband's murderer is extremely graceful and impressive. It reminded me of Pope John Paul II meeting with his shooter.
But words are only the beginning; true forgiveness requires action.
Actions are more powerful than words.
But words are only the beginning; true forgiveness requires action.
Actions are more powerful than words.
September 22, 2025 at 10:06 AM
Erika Kirk forgiving her husband's murderer is extremely graceful and impressive. It reminded me of Pope John Paul II meeting with his shooter.
But words are only the beginning; true forgiveness requires action.
Actions are more powerful than words.
But words are only the beginning; true forgiveness requires action.
Actions are more powerful than words.
The most underrated multi-generational personal finance hack:
Have your kids participate in 4H. Use the proceeds to fund a Roth IRA.
Even without a single additional dollar afterward, a fully funded Roth from ages 8 to 18 will be ~$2M at retirement.
Have your kids participate in 4H. Use the proceeds to fund a Roth IRA.
Even without a single additional dollar afterward, a fully funded Roth from ages 8 to 18 will be ~$2M at retirement.
September 21, 2025 at 12:24 PM
The most underrated multi-generational personal finance hack:
Have your kids participate in 4H. Use the proceeds to fund a Roth IRA.
Even without a single additional dollar afterward, a fully funded Roth from ages 8 to 18 will be ~$2M at retirement.
Have your kids participate in 4H. Use the proceeds to fund a Roth IRA.
Even without a single additional dollar afterward, a fully funded Roth from ages 8 to 18 will be ~$2M at retirement.
The latest scientific paper I co-authored has been published.
Our team investigated the effect of TGF-B on the ARKADIA-SKI axis for the stability of Treg cells, an anti-inflammatory T cell, which have shown promise as a cell therapy.
share.google/k6xMSDuRSntk...
Our team investigated the effect of TGF-B on the ARKADIA-SKI axis for the stability of Treg cells, an anti-inflammatory T cell, which have shown promise as a cell therapy.
share.google/k6xMSDuRSntk...
Frontiers | Differential regulation of Treg stability in human naïve and effector Treg subsets by TGFβ-signaling via ARKADIA-SKI axis
IntroductionThe human FOXP3+ regulatory T (Treg) cells, a subset of CD4+ T cells with immunosuppressive function, are essential for the maintenance of immune...
share.google
September 19, 2025 at 12:41 PM
The latest scientific paper I co-authored has been published.
Our team investigated the effect of TGF-B on the ARKADIA-SKI axis for the stability of Treg cells, an anti-inflammatory T cell, which have shown promise as a cell therapy.
share.google/k6xMSDuRSntk...
Our team investigated the effect of TGF-B on the ARKADIA-SKI axis for the stability of Treg cells, an anti-inflammatory T cell, which have shown promise as a cell therapy.
share.google/k6xMSDuRSntk...
My first official task as a member of the Frederick County Soil Conservation District: spending the day at the county fair teaching kids about the importance of soil!
September 18, 2025 at 1:14 PM
My first official task as a member of the Frederick County Soil Conservation District: spending the day at the county fair teaching kids about the importance of soil!
A yellow jacket sting reduced my ganglion cyst by ~80%.
After a single sting in my hand, I had a "large local reaction" for ~48 hours: massive swelling w/o pulmonary, neuro, or GI symptoms.
Now that the swelling has resided, my ganglion cyst is basically gone.
After a single sting in my hand, I had a "large local reaction" for ~48 hours: massive swelling w/o pulmonary, neuro, or GI symptoms.
Now that the swelling has resided, my ganglion cyst is basically gone.
September 18, 2025 at 10:43 AM
A yellow jacket sting reduced my ganglion cyst by ~80%.
After a single sting in my hand, I had a "large local reaction" for ~48 hours: massive swelling w/o pulmonary, neuro, or GI symptoms.
Now that the swelling has resided, my ganglion cyst is basically gone.
After a single sting in my hand, I had a "large local reaction" for ~48 hours: massive swelling w/o pulmonary, neuro, or GI symptoms.
Now that the swelling has resided, my ganglion cyst is basically gone.
With paternity time over, I'm back in the saddle developing next-generation cell and gene therapies.
September 16, 2025 at 12:07 PM
With paternity time over, I'm back in the saddle developing next-generation cell and gene therapies.
I am finding out the hard way that yellow jacket stings are more severe than honeybee stings.
September 14, 2025 at 7:00 PM
I am finding out the hard way that yellow jacket stings are more severe than honeybee stings.
Chestnuts and coonhound at dawn.
September 14, 2025 at 11:20 AM
Chestnuts and coonhound at dawn.
Quite the melancholy came over me when I realized that it's been over ten years since this tweet.
September 11, 2025 at 12:21 PM
Quite the melancholy came over me when I realized that it's been over ten years since this tweet.
You should be reading Albert Camus.
September 11, 2025 at 10:04 AM
You should be reading Albert Camus.
"People are now planting bombs in the tramways of Algiers. My mother might be on one of those trams. If that is justice, then I prefer my mother." - Albert Camus
September 10, 2025 at 8:01 PM
"People are now planting bombs in the tramways of Algiers. My mother might be on one of those trams. If that is justice, then I prefer my mother." - Albert Camus