Defended my PhD last week! It’s been an incredible journey filled with challenges and exciting science. I'm deeply grateful to everyone who was part of it -especially @metorrespadilla.bsky.social for taking me on this ride. #PhDone 🎓

#LeibnizPreis für exzellente Forschung in der #Epigenetik: Welche Mechanismen liegen der Zellplastizität und Reprogrammierung von Zellen zugrunde? An der Antwort, die zukünftig bei der Heilung von Organen helfen könnte, arbeitet Maria-Elena Torres-Padilla @metorrespadilla.bsky.social. Gratulation!

We’re proud to announce #OvoLabs, co-founded by Melina
@schuhlab.bsky.social, Agata Zielinska, and Oleksandr Yagensky. Building on decades of meiosis research, Ovo Labs aims to pioneer novel therapies to overcome the challenges of age-related infertility.

Now online! The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathways

How DNA Self-Organizes in the Early Embryo 🧬

The new insights challenge the classical model of genome organization & could lead to new disease treatments.

👉 t1p.de/25q7l

@metorrespadilla.bsky.social @palmrinmoy.bsky.social @epihmgu.bsky.social @lmumuenchen.bsky.social

Here is-🥳🥳😇 tremendous effort by @palmrinmoy.bsky.social brilliantly supported by @tamas-schauer.bsky.social &super help by federico,iliya,tsune,adam,@mamartirenom.bsky.social

Very happy to see this come to fruition- Look forward to feedback from colleagues !

More 👉 www.cell.com/cell/fulltex...

How does the genome find its place in the 3D space of the nucleus after fertilization?

Out now @cellcellpress.bsky.social:
cell.com/cell/fulltext/…

👇 A thread 👇

In this study, Hermant et al. describe the evolution of the retrotransposon MERVL and its cis-regulatory transcription factor binding motifs, highlighting the phyloregulatory adaptation at play during early embryogenesis.

Learn more here:
➡️ tinyurl.com/gd352270

🚨New paper alert!

RIF1 as a key in vivo regulator of replication timing consolidation during early mammalian development.

Another great collaborative effort from my time in the @metorrespadilla.bsky.social lab. Excited to see this one out!!

we've put a Review together 👇

Just came out at www.nature.com/articles/s41...

hoping it is useful for those in the field but also for those not in the field who would like an overview on chromatin/epigenetics/replication/nuclear organisation in early embryos

Enjoy :) - feedback welcome

#LeibnizPrize 2025: Celebrating Excellence!🎉

👏Yesterday, Prof. Maria-Elena Torres-Padilla officially received the Gottfried Wilhelm Leibniz Prize from the German Research Foundation (DFG)!
👉 t1p.de/s6uma

🎥Watch her portrait:
t1p.de/a30vo

@metorrespadilla.bsky.social @dfg.de
#LeibnizPreis

If you are interested in antigenic variation, you may have wondered how parasites ‘select’ which antigen to express next.

Our manuscript, just published in Nature, provides some answers!

www.nature.com/articles/s41...

@lmumuenchen.bsky.social
@erc.europa.eu a.eu
@nature.com

🚨New Paper Alert!

Check the news about the sucessful research led by our Director at IES here: 👉 t1p.de/d87p5.

Original paper at @genesdev.bsky.social: genesdev.cshlp.org/content/earl...

Congrats to Clara Hermant, Michel Mourra-Diaz, @marliesoomen.bsky.social, Mrinmoy Pal & rest of authors!

SRF: A New Regulator of Retrotransposons and Early Embryonic Genes🧬

A team led by Prof. Maria-Elena Torres-Padilla, #HelmholtzMunich, has uncovered a key player in early embryonic development: SRF.

👉 t1p.de/d87p5

@metorrespadilla.bsky.social @epihmgu.bsky.social
#EmbryonicDevelopment #Epigenetics

Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex...
A short thread to highlight some of our findings 🧵

✨ Excited to share my latest preprint on how H3K4 methylation promotes transcriptional memory from gametes to embryos across a transcriptionally silent window — crucial for proper zygotic genome activation and development. 🐸🧬✨

📄 Check it out here:
doi.org/10.1101/2025...

👇 Highlights below

🚨New paper alert, at Cell Press! 🚀

Excited to share groundbreaking research from Helmholtz Munich led by @metorrespadilla.bsky.social; @marliesoomen.bsky.social & @diego-rt.bsky.social.

They've uncovered ancient viral DNA's role in early embryonic development!

👉 Original paper: shorturl.at/D7eCz