PURPOSE: the Pain Research Network
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painresearchers.bsky.social
PURPOSE: the Pain Research Network
@painresearchers.bsky.social
NIH-funded program uniting #pain #researchers across the continuum of #painresearch, from all disciplines and all career levels. http://PainResearchers.com
Reposted by PURPOSE: the Pain Research Network
Huerta et al. find that standard analgesics reliably reduce spontaneous neuropathic pain in preclinical models, mirroring clinical efficacy and highlighting the value of assessing non-evoked pain. Learn more in #PAIN bit.ly/4hHOvJU
November 25, 2025 at 9:00 PM
How is AI beginning to reshape pain research? Ep. 9 of the Pain Cohort Series features Anson Kairys, PhD, on how machine learning, deep learning, and large language models are informing pain assessment, treatment-response prediction, and research workflows.
Watch: painresearchers.com/media_center...
November 24, 2025 at 11:26 PM
Reposted by PURPOSE: the Pain Research Network
Big new paper from us published yesterday: The synaptic ectokinase VLK triggers the EphB2–NMDAR interaction to drive injury-induced pain
www.science.org/doi/10.1126/...
Led by @hajisciencebaji.bsky.social in my lab and a wonderful collaboration with Matthew Dalva's lab at Tulane
The synaptic ectokinase VLK triggers the EphB2–NMDAR interaction to drive injury-induced pain
Phosphorylation of hundreds of protein extracellular domains is mediated by two kinase families but the functional role of these kinases is underexplored. We find that the presynaptic release of the t...
www.science.org
November 21, 2025 at 6:13 PM
When is pain relief in a trial clinically meaningful? Join Christopher J. Miller and John T. Farrar as they explain how MCIDs help define real improvement in acute pain.

📅 Dec 3, 2025
🕚 11 AM PT / 2 PM ET
💻 Online

Register: painresearchers.com/events/151186
Minimum Clinically Important Differences in Acute Pain
PURPOSE Web Series: Navigating Careers in Research Wednesday, December 3, 20252:00 PM- 3:00 PM ET / 11:00 AM- 12:00 PM PT Topic:  Minimum Clinically Important Differences in Acute Pain Featuring: ...
painresearchers.com
November 20, 2025 at 11:12 PM