PAIN Reports
@painreports.bsky.social
PAIN Reports is an official publication of the International Association for the Study of Pain (IASP). An open access multidisciplinary journal, PAIN Reports promotes a readily accessible forum that advances research on pain.
Tantawy et al. find that lacosamide alleviates oxaliplatin-induced peripheral neuropathy by effectively reducing neuroinflammatory biomarkers and improving 12-item neurotoxicity questionnaire scores, similar to duloxetine. Learn more in #PainReports bit.ly/4qXIMnd
February 6, 2026 at 1:00 PM
Tantawy et al. find that lacosamide alleviates oxaliplatin-induced peripheral neuropathy by effectively reducing neuroinflammatory biomarkers and improving 12-item neurotoxicity questionnaire scores, similar to duloxetine. Learn more in #PainReports bit.ly/4qXIMnd
Hattori et al. find that pain and disability in patients with subacromial pain syndrome are associated with pain sensitization rather than with rotator cuff-related factors. Learn more in #PainReports bit.ly/4qK653J
February 5, 2026 at 1:00 PM
Hattori et al. find that pain and disability in patients with subacromial pain syndrome are associated with pain sensitization rather than with rotator cuff-related factors. Learn more in #PainReports bit.ly/4qK653J
Ishikawa et al. find that offset analgesia reflects stochastic integration processes of prediction and observation with noise filtering for robust pain perception, offering a revision of pain perception theories. Learn more in #PainReports bit.ly/4aktJhw
February 4, 2026 at 1:00 PM
Ishikawa et al. find that offset analgesia reflects stochastic integration processes of prediction and observation with noise filtering for robust pain perception, offering a revision of pain perception theories. Learn more in #PainReports bit.ly/4aktJhw
Clarke et al. find that high-frequency stimulation increased neural activity in pain-related brain regions and altered functional connectivity between key areas of pain modulation, as measured using fMRI. Learn more in #PainReports bit.ly/45FHyEx
February 3, 2026 at 1:00 PM
Clarke et al. find that high-frequency stimulation increased neural activity in pain-related brain regions and altered functional connectivity between key areas of pain modulation, as measured using fMRI. Learn more in #PainReports bit.ly/45FHyEx
Winther et al. find that the effects of acute pain and acute itch are similar on the bilateral corticospinal tract excitability, with corticospinal excitability decreasing in the targeted hand muscle. Learn more in #PainReports bit.ly/4qNLA6n
February 2, 2026 at 1:00 PM
Winther et al. find that the effects of acute pain and acute itch are similar on the bilateral corticospinal tract excitability, with corticospinal excitability decreasing in the targeted hand muscle. Learn more in #PainReports bit.ly/4qNLA6n
Lu et al. find that trait mindfulness plays a moderating role in the relationship between EEG responses to pain stimulation and pain perception. Learn more in #PainReports bit.ly/49zUb6z
January 30, 2026 at 1:00 PM
Lu et al. find that trait mindfulness plays a moderating role in the relationship between EEG responses to pain stimulation and pain perception. Learn more in #PainReports bit.ly/49zUb6z
The OptiMeth-CRPS methodological framework presents strategies for optimizing the quality of clinical trials of interventions for complex regional pain syndrome as a rare pain condition. Learn more in Smart et al. #PainReports bit.ly/4sYC02a
January 28, 2026 at 1:00 PM
The OptiMeth-CRPS methodological framework presents strategies for optimizing the quality of clinical trials of interventions for complex regional pain syndrome as a rare pain condition. Learn more in Smart et al. #PainReports bit.ly/4sYC02a
Camara et al. find that chronic pain is independently associated with mortality irrespective of other covariates among Japanese rural women aged ≤74 years in the Shika town longitudinal cohort study, Japan. Learn more in #PainReports bit.ly/3NywCT5
January 26, 2026 at 1:00 PM
Camara et al. find that chronic pain is independently associated with mortality irrespective of other covariates among Japanese rural women aged ≤74 years in the Shika town longitudinal cohort study, Japan. Learn more in #PainReports bit.ly/3NywCT5
Allmendinger et al. find that chronic CRPS exhibits intact conditioned pain modulation, suggesting the importance of impaired pain facilitatory rather than pain inhibitory processes. Learn more in #PainReports bit.ly/4rg93x1
January 23, 2026 at 1:00 PM
Allmendinger et al. find that chronic CRPS exhibits intact conditioned pain modulation, suggesting the importance of impaired pain facilitatory rather than pain inhibitory processes. Learn more in #PainReports bit.ly/4rg93x1
During a 12-month observation, Higgins et al. found that chronic pain was associated with greater unscheduled health care utilization. Risk factors included analgesic tapering and transitioning from opioid to nonopioid analgesics #PainReports bit.ly/4pHVzbU
January 21, 2026 at 1:00 PM
During a 12-month observation, Higgins et al. found that chronic pain was associated with greater unscheduled health care utilization. Risk factors included analgesic tapering and transitioning from opioid to nonopioid analgesics #PainReports bit.ly/4pHVzbU
Hoq et al. examine translational rodent models of repeated neonatal pain and sucrose exposure, highlighting neurodevelopmental effects and their relevance to clinical care in preterm infants. Learn more in #PainReports bit.ly/4qmHcea
January 19, 2026 at 1:00 PM
Hoq et al. examine translational rodent models of repeated neonatal pain and sucrose exposure, highlighting neurodevelopmental effects and their relevance to clinical care in preterm infants. Learn more in #PainReports bit.ly/4qmHcea
Liu et al. find that bone marrow mesenchymal stem cell-derived exosomes alleviate chronic visceral pain and anxiety in rats with irritable bowel syndrome by activating Nrf-2/HO-1 and reducing oxidative stress. Learn more in #PainReports bit.ly/3Lqsh3q
January 16, 2026 at 1:00 PM
Liu et al. find that bone marrow mesenchymal stem cell-derived exosomes alleviate chronic visceral pain and anxiety in rats with irritable bowel syndrome by activating Nrf-2/HO-1 and reducing oxidative stress. Learn more in #PainReports bit.ly/3Lqsh3q
Yamanaka et al. find that chronic intrathecal JNK inhibition alleviated neuropathic pain and reduced pGAP-43 immunoreactivity in axon terminals, also preventing injury-induced hypertrophy of L1-CAM–labeled varicosities in the dorsal horn #PainReports bit.ly/4q6PFlG
January 14, 2026 at 1:00 PM
Yamanaka et al. find that chronic intrathecal JNK inhibition alleviated neuropathic pain and reduced pGAP-43 immunoreactivity in axon terminals, also preventing injury-induced hypertrophy of L1-CAM–labeled varicosities in the dorsal horn #PainReports bit.ly/4q6PFlG
Pedersen et al. find that IBA1- and GFAP-positive cells in dogs with syringomyelia and neuropathic pain may show transcriptomic changes reflecting altered reactivity, upregulated inflammatory processes, and downregulated immune functions #PainReports bit.ly/4qPBCkB
January 12, 2026 at 1:00 PM
Pedersen et al. find that IBA1- and GFAP-positive cells in dogs with syringomyelia and neuropathic pain may show transcriptomic changes reflecting altered reactivity, upregulated inflammatory processes, and downregulated immune functions #PainReports bit.ly/4qPBCkB
Dol et al. identify 15 unique digital health solutions, primarily videos, from 33 publications related to digital health solutions for caregivers of children experiencing acute pain. Learn more in #PainReports bit.ly/4pkwaWy
December 12, 2025 at 1:00 PM
Dol et al. identify 15 unique digital health solutions, primarily videos, from 33 publications related to digital health solutions for caregivers of children experiencing acute pain. Learn more in #PainReports bit.ly/4pkwaWy
Hamwi et al. use machine learning to classify EEG responses in preterm infants, distinguishing between pain and non-pain-related stimuli, offering a step toward improving real-time NICU pain monitoring. Learn more in #PainReports bit.ly/4rCoPTw
December 10, 2025 at 1:00 PM
Hamwi et al. use machine learning to classify EEG responses in preterm infants, distinguishing between pain and non-pain-related stimuli, offering a step toward improving real-time NICU pain monitoring. Learn more in #PainReports bit.ly/4rCoPTw
Menlah et al. identify the unique challenges faced by nurses and describe strategies in managing pediatric pain in a middle-income country. Learn more in #PainReports bit.ly/3Yaroi8
December 8, 2025 at 1:00 PM
Menlah et al. identify the unique challenges faced by nurses and describe strategies in managing pediatric pain in a middle-income country. Learn more in #PainReports bit.ly/3Yaroi8
Buchshtav et al. find that children undergoing air enema reduction of ileocolic intussusception without sedation or analgesia experience considerable pain-related distress. Learn more in #PainReports bit.ly/3LT3Wn1
December 5, 2025 at 1:00 PM
Buchshtav et al. find that children undergoing air enema reduction of ileocolic intussusception without sedation or analgesia experience considerable pain-related distress. Learn more in #PainReports bit.ly/3LT3Wn1
Schlisio et al. find that the relationship between transgender identity and neuroplasticity suggests a potential influence on the occurrence of phantom limb pain after gender-affirming surgery. Learn more in #PainReports bit.ly/4809jt8
December 3, 2025 at 1:00 PM
Schlisio et al. find that the relationship between transgender identity and neuroplasticity suggests a potential influence on the occurrence of phantom limb pain after gender-affirming surgery. Learn more in #PainReports bit.ly/4809jt8
Although the subjective nature of chronic pain symptoms challenges the medico-legal community, Assis et al. argue that physicians must provide unbiased reliable information and remain within the bounds of their competence. Learn more in #PainReports bit.ly/4rlopkl
December 1, 2025 at 4:00 PM
Although the subjective nature of chronic pain symptoms challenges the medico-legal community, Assis et al. argue that physicians must provide unbiased reliable information and remain within the bounds of their competence. Learn more in #PainReports bit.ly/4rlopkl
Appraising performance characteristics of the pain Numerical Rating Scale using marginal distribution analysis, Hogans et al. identify efficient pain metrics that represent clinical data more precisely than prior methods. Learn more in #PainReports bit.ly/4r98sxx
November 28, 2025 at 1:00 PM
Appraising performance characteristics of the pain Numerical Rating Scale using marginal distribution analysis, Hogans et al. identify efficient pain metrics that represent clinical data more precisely than prior methods. Learn more in #PainReports bit.ly/4r98sxx
Mendes Fernandes et al. report a negative gradient in rehabilitation performance with increasing WHO analgesic ladder; odds of achieving clinically important improvements weaker for low-dose chronic opioid users. Learn more in #PainReports bit.ly/4pdRrAw
November 26, 2025 at 1:00 PM
Mendes Fernandes et al. report a negative gradient in rehabilitation performance with increasing WHO analgesic ladder; odds of achieving clinically important improvements weaker for low-dose chronic opioid users. Learn more in #PainReports bit.ly/4pdRrAw
Janela et al. find that fear-avoidance beliefs and depression consistently predicted pain outcomes in digital rehabilitation for chronic musculoskeletal pain, emphasizing the importance of tailored, multimodal approaches to optimize recovery #PainReports bit.ly/3K4ziq7
November 24, 2025 at 1:00 PM
Janela et al. find that fear-avoidance beliefs and depression consistently predicted pain outcomes in digital rehabilitation for chronic musculoskeletal pain, emphasizing the importance of tailored, multimodal approaches to optimize recovery #PainReports bit.ly/3K4ziq7
O’Brien et al. find that an inflammatory peripheral blood immune environment, including platelet-neutrophil aggregation, matrix metalloproteinase 9 expression, and Th17 activation distinguishes migraine prodrome and attack #PainReports bit.ly/3WDJCbk
November 14, 2025 at 1:00 PM
O’Brien et al. find that an inflammatory peripheral blood immune environment, including platelet-neutrophil aggregation, matrix metalloproteinase 9 expression, and Th17 activation distinguishes migraine prodrome and attack #PainReports bit.ly/3WDJCbk
Umeda et al. find that the heightened pain sensitivity among Asian-American adults is not explained by their lower physical activity levels, but racial discrimination may contribute to it. Learn more in #PainReports bit.ly/43XS0pZ
November 12, 2025 at 1:00 PM
Umeda et al. find that the heightened pain sensitivity among Asian-American adults is not explained by their lower physical activity levels, but racial discrimination may contribute to it. Learn more in #PainReports bit.ly/43XS0pZ