A new review on suppressor-tRNA therapies, @ignatovalab.bsky.social and Suki Albers
A new review on suppressor-tRNA therapies, we wrote with Suki Albers 👇🏻
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Suppressor tRNAs as personalized therapy for nonsense mutation-associated pathologies
Nonsense mutations – associated with many devastating genetic disorders that currently lack effective treatments – prematurely terminate protein synth…
www.sciencedirect.com
August 28, 2025 at 9:17 PM
A new review on suppressor-tRNA therapies, @ignatovalab.bsky.social and Suki Albers
Reposted by Or Shahar
An overlooked aspect of becoming a scientist is realizing that you have a particular brand; a unique approach, an attraction to a certain kind of problem and a set of connections that you like to make. Uri calls it finding your internal tuning fork.
podcasts.apple.com/us/podcast/n...
podcasts.apple.com/us/podcast/n...
17 | Uri Alon and our internal tuning fork
Podcast Episode · Night Science · 05/31/2022 · 40m
podcasts.apple.com
August 17, 2025 at 12:34 AM
An overlooked aspect of becoming a scientist is realizing that you have a particular brand; a unique approach, an attraction to a certain kind of problem and a set of connections that you like to make. Uri calls it finding your internal tuning fork.
podcasts.apple.com/us/podcast/n...
podcasts.apple.com/us/podcast/n...
PhD mentor encouraging a student to participate in the conference’s social event
bsky.app/profile/snar...
bsky.app/profile/snar...
July 22, 2025 at 4:40 AM
PhD mentor encouraging a student to participate in the conference’s social event
bsky.app/profile/snar...
bsky.app/profile/snar...
Reposted by Or Shahar
Delighted to share our newest publication - beautiful collaboration with Ya-Ming Hou’s lab. If you wonder whether bacterial mRNAs contain m6A (yes they do) and whether it matters (does not seem to) look here 👇🏻
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
m6A modification is incorporated into bacterial mRNA without specific functional benefit
Abstract. N6-Methyladenosine (m6A), the most abundant modification in eukaryotic messenger RNAs (mRNAs), has also been found at a low level in bacterial mR
academic.oup.com
May 22, 2025 at 8:50 PM
Delighted to share our newest publication - beautiful collaboration with Ya-Ming Hou’s lab. If you wonder whether bacterial mRNAs contain m6A (yes they do) and whether it matters (does not seem to) look here 👇🏻
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Reposted by Or Shahar
So cool, a novel archaeon with a super small genome and no metabolic genes!
"An unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses."
www.biorxiv.org/content/10.1...
"An unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses."
www.biorxiv.org/content/10.1...
A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome
Defining the minimal genetic requirements for cellular life remains a fundamental question in biology. Genomic exploration continually reveals novel microbial lineages, often exhibiting extreme genome...
www.biorxiv.org
June 27, 2025 at 4:29 AM
So cool, a novel archaeon with a super small genome and no metabolic genes!
"An unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses."
www.biorxiv.org/content/10.1...
"An unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses."
www.biorxiv.org/content/10.1...
Reposted by Or Shahar
Today is June 25. On this date in 1903 Marie Curie defended her doctoral thesis on radioactive substances at Université de la Sorbonne in Paris, becoming 1st woman in France to receive a doctoral degree. Image shows the thesis cover.
June 25, 2025 at 6:02 AM
Today is June 25. On this date in 1903 Marie Curie defended her doctoral thesis on radioactive substances at Université de la Sorbonne in Paris, becoming 1st woman in France to receive a doctoral degree. Image shows the thesis cover.
Reposted by Or Shahar
🔥🔥🔥Check out our latest paper on the kidney, wonderful collaboration with Fabian Braun & Christine Kurschat @cecad.bsky.social. Read now: JCI Insight - Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage insight.jci.org/articles/vie...
June 24, 2025 at 2:09 PM
🔥🔥🔥Check out our latest paper on the kidney, wonderful collaboration with Fabian Braun & Christine Kurschat @cecad.bsky.social. Read now: JCI Insight - Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage insight.jci.org/articles/vie...
Reposted by Or Shahar
On chromatin and SNPs of aging @dannybar.bsky.social and colleagues
Our preprint "Reversible and Causal Epigenetic Information Loss in Liver Aging and Disease" is out! We've previously shown that looking at methylation sites that are very different in one tissue from all others allows us to observe epigenetic information is loss upon aging 1/3
June 15, 2025 at 10:31 AM
On chromatin and SNPs of aging @dannybar.bsky.social and colleagues
#TCTEAC get to the venue! 8:45
a train is leaving with the words the train is leaving now on the bottom
ALT: a train is leaving with the words the train is leaving now on the bottom
media.tenor.com
June 12, 2025 at 5:07 AM
#TCTEAC get to the venue! 8:45