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Ophthopedia
@ophthalmology.bsky.social
Latest updates on publications and news from #ophthalmology and #visionscience. Curated by @rohanbir.bsky.social.

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Ophthopedia Update: Immune Checkpoint Inhibitors for the Treatment of Periorbital Non-Melanoma Skin Cancers: .
Immune Checkpoint Inhibitors for the Treatment of Periorbital Non-Melanoma Skin Cancers
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dlvr.it
February 19, 2026 at 10:37 AM
Ophthopedia Update: Large Language Models Use in Dry Eye Disease: Correspondence: .
Large Language Models Use in Dry Eye Disease: Correspondence
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dlvr.it
February 19, 2026 at 10:37 AM
Ophthopedia Update: Outer Retinal Erosion and Outer Retinal Pinching at the Origin of Subretinal Fluidin Central Serous Chorioretinopathy: Central serous chorioretinopathy (CSCR) is an idiopathic macular disorder characterized by a serous neurosensory retinal… #Ophthalmology #Ophthotwitter #Scicomm
Outer Retinal Erosion and Outer Retinal Pinching at the Origin of Subretinal Fluidin Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSCR) is an idiopathic macular disorder characterized by a serous neurosensory retinal detachment where fluid originates from the choroid and reaches the subretinal space through a barrier defect of the retinal pigment epithelium (RPE). Its pathogenesis is not yet well defined and recognizes multiple risk factors that ultimately delineate a condition of choroidal overperfusion and choroidal veins dilation.1,2,3 While the literature of last years has increasingly turned its attention to the posterior ocular compartments, the choroid and the sclera.
dlvr.it
February 19, 2026 at 10:19 AM
Ophthopedia Update: IL-17–Related SNPs in Orbital Autoimmunity: Issues of Heterogeneity, Power, and Multiple Testing: Publication date: Available online 19 February 2026

Source: Experimental Eye Research

Author(s): Aditya K. Panda
IL-17–Related SNPs in Orbital Autoimmunity: Issues of Heterogeneity, Power, and Multiple Testing
Publication date: Available online 19 February 2026 Source: Experimental Eye Research Author(s): Aditya K. Panda
dlvr.it
February 19, 2026 at 10:15 AM
Ophthopedia Update: SREBP1-Driven SCD1 Protects Retinal Pigment Epithelium from Oxidative Damage by Activating the NRF2/GPX4 Axis: Publication date: Available online 18 February 2026

Source: Experimental Eye Research

Author(s): Xingyu Yang, Weichen Xu, Hang Xie, Xiaoyu Guo, Feiyan Zhu, Yiqiao…
SREBP1-Driven SCD1 Protects Retinal Pigment Epithelium from Oxidative Damage by Activating the NRF2/GPX4 Axis
Publication date: Available online 18 February 2026 Source: Experimental Eye Research Author(s): Xingyu Yang, Weichen Xu, Hang Xie, Xiaoyu Guo, Feiyan Zhu, Yiqiao Xing, Changzheng Chen
dlvr.it
February 19, 2026 at 10:15 AM
Ophthopedia Update: Assessment of the Effectiveness, Tolerability, and Safety of the Preservative-Free Fixed Combination of Timolol, Dorzolamide, and Brimonidine Compared to Separate Therapies in Patients with Glaucoma, a Randomized Controlled Trial #Ophthomology #Eye #Ophthotwitter
Assessment of the effectiveness, tolerability, and safety of the prese | OPTH
Noninferiority of preservative-free timolol, dorzolamide, and brimonidine combination for treating patients with uncontrolled primary open-angle glaucoma
dlvr.it
February 19, 2026 at 9:48 AM
Ophthopedia Update: To Evaluate the Agreement and Repeatability of the Eyerobo VS Portable Autorefractor Cycloplegic Refraction in Children and Adolescents #Ophthomology #Eye #Ophthotwitter
To evaluate the agreement and repeatability of the 2WIN-S portable aut | OPTH
To evaluate the repeatability & agreement of the Eyerobo VS with the ARK-1 & subjective refraction cycloplegic refraction in children & adolescents.
dlvr.it
February 19, 2026 at 8:00 AM
Ophthopedia Update: Response to ‘Comment on: ‘Neovascular glaucoma incidence and visual outcomes in treated proliferative diabetic retinopathy with anterior segment neovascularisation”: Eye, Published online: 18 February 2026;… #Ophthalmology #Eye #Ophthotwitter
Response to ‘Comment on: ‘Neovascular glaucoma incidence and visual outcomes in treated proliferative diabetic retinopathy with anterior segment neovascularisation”
Eye, Published online: 18 February 2026; doi:10.1038/s41433-026-04351-1Response to ‘Comment on: ‘Neovascular glaucoma incidence and visual outcomes in treated proliferative diabetic retinopathy with anterior segment neovascularisation”
dlvr.it
February 19, 2026 at 1:50 AM
Ophthopedia Update: Comment on: ‘Incidence and prevalence of mucous membrane pemphigoid with ocular involvement: a retrospective analysis using the TriNetX database’: Eye, Published online: 18 February 2026; doi:10.1038/s41433-026-04355-xComment on: ‘Incidence… #Ophthalmology #Eye #Ophthotwitter
Comment on: ‘Incidence and prevalence of mucous membrane pemphigoid with ocular involvement: a retrospective analysis using the TriNetX database’
Eye, Published online: 18 February 2026; doi:10.1038/s41433-026-04355-xComment on: ‘Incidence and prevalence of mucous membrane pemphigoid with ocular involvement: a retrospective analysis using the TriNetX database’
dlvr.it
February 19, 2026 at 1:50 AM
Ophthopedia Update: Preeclampsia and risk of ophthalmic complications: a large United States cohort study: Eye, Published online: 18 February 2026; doi:10.1038/s41433-026-04292-9Preeclampsia and risk of ophthalmic complications: a large United States cohort study #Ophthalmology #Eye #Ophthotwitter
Preeclampsia and risk of ophthalmic complications: a large United States cohort study
Eye, Published online: 18 February 2026; doi:10.1038/s41433-026-04292-9Preeclampsia and risk of ophthalmic complications: a large United States cohort study
dlvr.it
February 19, 2026 at 1:50 AM
Ophthopedia Update: Smoking and idiopathic intracranial hypertension: a meta-analysis: Eye, Published online: 18 February 2026; doi:10.1038/s41433-026-04282-xSmoking and idiopathic intracranial hypertension: a meta-analysis #Ophthalmology #Eye #Ophthotwitter
Smoking and idiopathic intracranial hypertension: a meta-analysis
Eye, Published online: 18 February 2026; doi:10.1038/s41433-026-04282-xSmoking and idiopathic intracranial hypertension: a meta-analysis
dlvr.it
February 19, 2026 at 1:50 AM
Ophthopedia Update: Axpaxli meets primary endpoint vs. aflibercept in wet AMD: In a phase 3 trial, Axpaxli, a tyrosine kinase inhibitor, achieved its superiority primary endpoint vs. aflibercept for the treatment of wet age-related macular degeneration, according to a… #ophthalmology #eye #eyenews
Axpaxli meets primary endpoint vs. aflibercept in wet AMD
In a phase 3 trial, Axpaxli, a tyrosine kinase inhibitor, achieved its superiority primary endpoint vs. aflibercept for the treatment of wet age-related macular degeneration, according to a press release from Ocular Therapeutix. “Despite advances in [neovascular age-related macular degeneration] treatment, there remains unpredictability around patient response to treatment, resulting in unsustainable burden and lack of adherence,” Pravin U. Dugel, MD, executive chairman, president and CEO of Ocular Therapeutix, told Healio. “In addition, fluid fluctuations and increased fibrosis lead to poor
dlvr.it
February 18, 2026 at 7:45 PM
Ophthopedia Update: Axpaxli meets primary endpoint vs. aflibercept in wet AMD: In a phase 3 trial, Axpaxli, a tyrosine kinase inhibitor, achieved its superiority primary endpoint vs. aflibercept for the treatment of wet age-related macular degeneration, according to a press release from Ocular…
Axpaxli meets primary endpoint vs. aflibercept in wet AMD
In a phase 3 trial, Axpaxli, a tyrosine kinase inhibitor, achieved its superiority primary endpoint vs. aflibercept for the treatment of wet age-related macular degeneration, according to a press release from Ocular Therapeutix. “Despite advances in [neovascular age-related macular degeneration] treatment, there remains unpredictability around patient response to treatment, resulting in unsustainable burden and lack of adherence,” Pravin U. Dugel, MD, executive chairman, president and CEO of Ocular Therapeutix, told Healio. “In addition, fluid fluctuations and increased fibrosis lead to poor
dlvr.it
February 18, 2026 at 7:45 PM
Ophthopedia Update: Financial hardship has significant impact on cancer-related pain: Patients who have financial hardships have a significantly higher likelihood of experiencing moderate or severe cancer-related pain than those who do not.
A retrospective analysis… #ophthalmology #eye #eyenews
Financial hardship has significant impact on cancer-related pain
Patients who have financial hardships have a significantly higher likelihood of experiencing moderate or severe cancer-related pain than those who do not. A retrospective analysis also showed patients with financial hardship have higher rates of opioid use, despite their fiscal condition. “Financial hardship is clinically impactful,” Courtney P. Williams, DrPH, assistant professor in the division of General Internal Medicine and Population Science at The University of Alabama at Birmingham (UAB) Heersink School of Medicine and associate scientist at O’Neal Comprehensive Cancer Center, told
dlvr.it
February 18, 2026 at 7:23 PM
Ophthopedia Update: Weekly Journal Update — February 18, 2026: Emergency department imaging protocol for triaging visual symptoms, prefilled syringes and endophthalmitis rates, GLP-1 RAs and sight-threatening diabetic retinopathy, lactic acid as a uveal melanoma marker, drugs… #Ophthalmology #News
Weekly Journal Update — February 18, 2026
Emergency department imaging protocol for triaging visual symptoms, prefilled syringes and endophthalmitis rates, GLP-1 RAs and sight-threatening diabetic retinopathy, lactic acid as a uveal melanoma marker, drugs associated with cataracts in children.
dlvr.it
February 18, 2026 at 7:20 PM
Ophthopedia Update: A series of ruptured dermoid cysts in pediatric patients: Ruptured dermoid cysts can often have atypical presentations and be challenging to manage. We report 3 cases of pediatric patients with ruptured dermoid cysts. Case 1 was a 16-year-old… #Ophthalmology #Eye #Ophthotwitter
A series of ruptured dermoid cysts in pediatric patients
Ruptured dermoid cysts can often have atypical presentations and be challenging to manage. We report 3 cases of pediatric patients with ruptured dermoid cysts. Case 1 was a 16-year-old boy with an enlarging left superotemporal orbital mass who presented with 2 days of acute inflammation. Computed tomography revealed a well-circumscribed lesion that was excised. Histopathology confirmed a ruptured dermoid cyst. Case 2 was a 4-year-old girl with a right superotemporal orbital mass that enlarged following trauma.
dlvr.it
February 18, 2026 at 7:18 PM
Ophthopedia Update: Aqueous humour outflow improvement after excimer laser trabeculostomy: The purpose of the study was to investigate changes in aqueous humour outflow (AHO) after the Elios glaucoma procedure (excimer laser trabeculostomy, ELT) using sequential… #Ophthalmology #Ophthotwitter #BJO
Aqueous humour outflow improvement after excimer laser trabeculostomy
The purpose of the study was to investigate changes in aqueous humour outflow (AHO) after the Elios glaucoma procedure (excimer laser trabeculostomy, ELT) using sequential AHO angiography. AHO angiography using two different tracers was performed in six eyes of five patients undergoing cataract surgery combined with ELT. AHO was compared in regions of interest in the nasal quadrant. AHO improved significantly after ELT (p=0.03) overall, and each patient showed individual, qualitative AHO improvement. Interestingly, AHO improvement extended beyond the site of ELT application. Further studies are needed to investigate the correlation of AHO improvement and clinical efficacy.
dlvr.it
February 18, 2026 at 5:44 PM
Ophthopedia Update: Subjective and objective refraction using autorefraction and two wavefront-based aberrometers in EDOF and simultaneous vision intraocular lenses: Accurate assessment of refractive error remains a cornerstone in ophthalmic practice. The… #Ophthalmology #Ophthotwitter #Scicomm
Subjective and objective refraction using autorefraction and two wavefront-based aberrometers in EDOF and simultaneous vision intraocular lenses
Accurate assessment of refractive error remains a cornerstone in ophthalmic practice. The current gold standard is subjective refraction (SR), as it is considered to provide the most precise refractive status. Autorefractors have been routinely used in clinics to facilitate efficient daily ophthalmic workflow, offering a relatively rapid assessment of objective refraction (OR). In recent years, multifunctional diagnostic devices have gained considerable popularity. These systems combine OR with additional modalities such as aberrometry, tomo- and/or topography.
dlvr.it
February 18, 2026 at 5:08 PM
Ophthopedia Update: Mismatch Repair Deficiency in Benign and Atypical Ocular Sebaceous Neoplasms: Implications for Muir–Torre Screening and Classification: Muir–Torre syndrome (MTS), a variant of Lynch syndrome characterized by visceral malignancies and… #Ophthalmology #Ophthotwitter #Scicomm
Mismatch Repair Deficiency in Benign and Atypical Ocular Sebaceous Neoplasms: Implications for Muir–Torre Screening and Classification
Muir–Torre syndrome (MTS), a variant of Lynch syndrome characterized by visceral malignancies and cutaneous sebaceous neoplasms, is defined by germline pathogenic variants in mismatch repair (MMR) genes. These Lynch-associated cancers include colorectal, endometrial, ovarian, and small bowel cancers, as well as tumors of the urinary tract and biliary tract.1 The most common sebaceous neoplasm in the periocular region is conventional poorly differentiated sebaceous carcinoma, a high-grade basaloid carcinoma usually without any mature sebocytic differentiation and frequently showing TP53 mutation and/or RB1 loss, which is generally not related to MMR deficiency or MTS.
dlvr.it
February 18, 2026 at 5:08 PM
Ophthopedia Update: Patterns of Ellipsoid Zone Loss May Predict Progression in MacTel: A longitudinal OCT imaging study identified three distinct patterns of ellipsoid zone loss in macular telangiectasia type 2 (MacTel) corresponding with different rates of disease progression. #Ophthalmology #News
Patterns of Ellipsoid Zone Loss May Predict Progression in MacTel
A longitudinal OCT imaging study identified three distinct patterns of ellipsoid zone loss in macular telangiectasia type 2 (MacTel) corresponding with different rates of disease progression.
dlvr.it
February 18, 2026 at 5:05 PM
Ophthopedia Update: Ophthalmologists: Encourage use of protective eye wear in sports: Sports-related injuries are extremely common in every eye doctor’s practice.
These injuries are more common in younger patients between the ages of 10 and 19 years, in male patients,… #ophthalmology #eye #eyenews
Ophthalmologists: Encourage use of protective eye wear in sports
Sports-related injuries are extremely common in every eye doctor’s practice. These injuries are more common in younger patients between the ages of 10 and 19 years, in male patients, during competition vs. practice and especially when protective eye wear is not used. For example, 97% of injuries in basketball, baseball/softball and fishing occur in individuals not wearing protective eye wear. The common causes include trauma from balls, hands/fingers, heads, knees, elbows, rackets/sticks and fishing lures/rods. Common injuries, in elevating severity, include periocular contusion,
dlvr.it
February 18, 2026 at 4:37 PM
Ophthopedia Update: Ophthalmologists: Encourage use of protective eye wear in sports: Sports-related injuries are extremely common in every eye doctor’s practice.
These injuries are more common in younger patients between the ages of 10 and 19 years, in male patients, during competition vs.…
Ophthalmologists: Encourage use of protective eye wear in sports
Sports-related injuries are extremely common in every eye doctor’s practice. These injuries are more common in younger patients between the ages of 10 and 19 years, in male patients, during competition vs. practice and especially when protective eye wear is not used. For example, 97% of injuries in basketball, baseball/softball and fishing occur in individuals not wearing protective eye wear. The common causes include trauma from balls, hands/fingers, heads, knees, elbows, rackets/sticks and fishing lures/rods. Common injuries, in elevating severity, include periocular contusion,
dlvr.it
February 18, 2026 at 4:37 PM
Ophthopedia Update: Alcon launches Total30 monthly multifocal toric lens in US: Editor’s note: This is a developing news story. Please check back soon for updates.
Total30 multifocal for astigmatism, a monthly toric lens for patients with presbyopia, is now available in the U.S., according to a…
Alcon launches Total30 monthly multifocal toric lens in US
Editor’s note: This is a developing news story. Please check back soon for updates. Total30 multifocal for astigmatism, a monthly toric lens for patients with presbyopia, is now available in the U.S., according to a press release from Alcon. The lens features Alcon’s water gradient technology, enabling its surface to be “nearly 100%” water, as well as ultraviolet blocking and blue-violet light filtration, according to the release. It also uses Alcon’s Celligent technology to work against bacteria and lipid deposits. The lens leverages the company’s Precision
dlvr.it
February 18, 2026 at 2:53 PM
Ophthopedia Update: Alcon launches Total30 monthly multifocal toric lens in US: Editor’s note: This is a developing news story. Please check back soon for updates.
Total30 multifocal for astigmatism, a monthly toric lens for patients with presbyopia, is now available… #ophthalmology #eye #eyenews
Alcon launches Total30 monthly multifocal toric lens in US
Editor’s note: This is a developing news story. Please check back soon for updates. Total30 multifocal for astigmatism, a monthly toric lens for patients with presbyopia, is now available in the U.S., according to a press release from Alcon. The lens features Alcon’s water gradient technology, enabling its surface to be “nearly 100%” water, as well as ultraviolet blocking and blue-violet light filtration, according to the release. It also uses Alcon’s Celligent technology to work against bacteria and lipid deposits. The lens leverages the company’s Precision
dlvr.it
February 18, 2026 at 2:53 PM
Ophthopedia Update: Senate committee holds hearing on physician burnout: Expert witnesses discussed the impact of federal regulations and administrative burden on physician burnout in a recent hearing held by the U.S. Senate Special Committee on Aging.
“Today, we will… #ophthalmology #eye #eyenews
Senate committee holds hearing on physician burnout
Expert witnesses discussed the impact of federal regulations and administrative burden on physician burnout in a recent hearing held by the U.S. Senate Special Committee on Aging. “Today, we will look at how Washington’s regulations and red tape play into this crisis, and what we can do to fix it so our doctors can spend more time caring for patients and less time navigating bureaucracy,” committee chairman Sen. Rick Scott (R-Fla.), said in his opening statement. “We’ll hear from witnesses who interact with physicians at all levels.” Key points of discussion included difficulties managing
dlvr.it
February 18, 2026 at 2:44 PM