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Ophthopedia
@ophthalmology.bsky.social
Latest updates on publications and news from #ophthalmology and #visionscience. Curated by @rohanbir.bsky.social.

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Ophthopedia Update: Misdiagnosis in Referrals for Advanced Retinopathy of Prematurity: Among 74 infants referred for stage 4–5 ROP, 24% were misdiagnosed and later identified as having different retinal conditions, including FEVR, Coats disease, incontinentia… #Ophthalmology #Retina #Ophthotwitter
Misdiagnosis in Referrals for Advanced Retinopathy of Prematurity
Among 74 infants referred for stage 4–5 ROP, 24% were misdiagnosed and later identified as having different retinal conditions, including FEVR, Coats disease, incontinentia pigmenti, dyskeratosis congenita, CAPN5- and DOCK6-related retinopathies, or ocular toxoplasmosis. Imaging and genetic testing were decisive in preventing misdiagnosis.
dlvr.it
February 20, 2026 at 1:19 PM
Ophthopedia Update: Intravitreal Methotrexate After Retinal Detachment Repair: A Canadian Retrospective Cohort Study of Feasibility and Safety: Publication date: Available online 19 February 2026

Source: AJO International

Author(s): Robert T. Moore, Abdullah… #Ophthalmology #AJOInternational
Intravitreal Methotrexate After Retinal Detachment Repair: A Canadian Retrospective Cohort Study of Feasibility and Safety
Publication date: Available online 19 February 2026 Source: AJO International Author(s): Robert T. Moore, Abdullah Al-Ani, Corrina Azarcon, Shellina Kherani, Rajinder Nirwan, Geoff Williams, Amin Kherani
dlvr.it
February 20, 2026 at 11:35 AM
Ophthopedia Update: UNSOLVED RETINAL QUESTIONS: Publication date: Available online 19 February 2026

Source: Progress in Retinal and Eye Research

Author(s): John E. Dowling, Frank S. Werblin, Samuel M. Wu
UNSOLVED RETINAL QUESTIONS
Publication date: Available online 19 February 2026 Source: Progress in Retinal and Eye Research Author(s): John E. Dowling, Frank S. Werblin, Samuel M. Wu
dlvr.it
February 20, 2026 at 11:22 AM
Ophthopedia Update: Proanthocyanidins Inhibit the Inflammation Response of Dry Eye by Regulating IRAK4/JAK1/STAT1 Signaling Pathway: Publication date: Available online 20 February 2026

Source: Experimental Eye Research

Author(s): Ying Lian, Wenjing Jiang, Zhen Fan, Jiachao Shen
Proanthocyanidins Inhibit the Inflammation Response of Dry Eye by Regulating IRAK4/JAK1/STAT1 Signaling Pathway
Publication date: Available online 20 February 2026 Source: Experimental Eye Research Author(s): Ying Lian, Wenjing Jiang, Zhen Fan, Jiachao Shen
dlvr.it
February 20, 2026 at 10:50 AM
Ophthopedia Update: miR-138-5p overexpression inhibits limbal epithelial cell proliferation and induces cell cycle arrest, in vitro: Publication date: Available online 19 February 2026

Source: Experimental Eye Research

Author(s): Shweta Suiwal, Tanja Stachon, Virendra Kumar, Fabian N. Fries,…
miR-138-5p overexpression inhibits limbal epithelial cell proliferation and induces cell cycle arrest, in vitro
Publication date: Available online 19 February 2026 Source: Experimental Eye Research Author(s): Shweta Suiwal, Tanja Stachon, Virendra Kumar, Fabian N. Fries, Shao-Lun Hsu, Shanhe Liu, Shuailin Li, Swarnali Kundu, Berthold Seitz, Maryam Amini, Nóra Szentmáry
dlvr.it
February 20, 2026 at 10:50 AM
Ophthopedia Update: Lacrimal History – Part 103: Doyens of Dacryology Series – Alexander Mackay Geddes (1794–1824) and His 1816 Dissertation on Lacrimal Fistula: .
Lacrimal History – Part 103: Doyens of Dacryology Series – Alexander Mackay Geddes (1794–1824) and His 1816 Dissertation on Lacrimal Fistula
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dlvr.it
February 20, 2026 at 10:46 AM
Ophthopedia Update: Comparison of Seasonal Variation in Myopia Progression: Defocus Incorporated Multiple Segment Spectacle Lenses in Combination with 0.01% Atropine vs Orthokeratology #Ophthomology #Eye #Ophthotwitter
Comparison of seasonal variation in myopia progression: defocus incorp | OPTH
Seasonal variations in axial length in myopic children with defocus incorporated multiple segments spectacle lenses combined with DIMSA and OK lenses
dlvr.it
February 20, 2026 at 9:02 AM
Ophthopedia Update: Reversal of Pharmacologic Mydriasis in Pediatric Subjects with Ryzumvi (0.75% Phentolamine Ophthalmic Solution): A Post-Hoc Pooled Analysis from Three Randomized, Placebo-Controlled Phase 3 Trials #Ophthomology #Eye #Ophthotwitter
Reversal of Pharmacologically-Induced Mydriasis in Healthy Pediatric S | OPTH
In this report, we provide a post-hoc pooled of all 68 pediatric subjects aged 3 to 17 years enrolled in the three Phase 3 MIRA trials.
dlvr.it
February 20, 2026 at 8:58 AM
Ophthopedia Update: Zenlens Chroma HOA reduces higher-order aberrations: Higher-order aberrations were corrected by around 75% in eyes with keratoconus fitted with Zenlens Chroma HOA, according to data presented at the Global Specialty Lens Symposium.
“Patients with keratoconus absolutely gain the…
Zenlens Chroma HOA reduces higher-order aberrations
Higher-order aberrations were corrected by around 75% in eyes with keratoconus fitted with Zenlens Chroma HOA, according to data presented at the Global Specialty Lens Symposium. “Patients with keratoconus absolutely gain the most [from higher-order aberration-correcting lenses], and that has everything to do with the back surface of their cornea,” Jason Jedlicka, OD, FAAO, FSLS, clinical professor and chief of cornea and contact lens service at Indiana University School of Optometry, told Healio. “It’s the posterior cornea that creates the [higher-order aberrations]
dlvr.it
February 19, 2026 at 8:22 PM
Ophthopedia Update: Infographic: effect of initial management with aflibercept vs laser photocoagulation vs observation on vision loss among patients with diabetic macular edema involving the centre of the macula and good visual acuity (DRCR Protocol V Study):… #Ophthalmology #Eye #Ophthotwitter
Infographic: effect of initial management with aflibercept vs laser photocoagulation vs observation on vision loss among patients with diabetic macular edema involving the centre of the macula and good visual acuity (DRCR Protocol V Study)
Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04323-5Infographic: effect of initial management with aflibercept vs laser photocoagulation vs observation on vision loss among patients with diabetic macular edema involving the centre of the macula and good visual acuity (DRCR Protocol V Study)
dlvr.it
February 19, 2026 at 7:33 PM
Ophthopedia Update: Infographic: study design of the QUASAR randomised trial of aflibercept 8 mg in retinal vein occlusion: Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04246-1Infographic: study design of the QUASAR randomised trial of… #Ophthalmology #Eye #Ophthotwitter
Infographic: study design of the QUASAR randomised trial of aflibercept 8 mg in retinal vein occlusion
Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04246-1Infographic: study design of the QUASAR randomised trial of aflibercept 8 mg in retinal vein occlusion
dlvr.it
February 19, 2026 at 7:33 PM
Ophthopedia Update: Peripheral vascular scorching with posterior pole ember glow—hyperacute outer retinal dysfunction: Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04312-8Peripheral vascular scorching with posterior pole ember glow—hyperacute… #Ophthalmology #Eye #Ophthotwitter
Peripheral vascular scorching with posterior pole ember glow—hyperacute outer retinal dysfunction
Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04312-8Peripheral vascular scorching with posterior pole ember glow—hyperacute outer retinal dysfunction
dlvr.it
February 19, 2026 at 7:33 PM
Ophthopedia Update: Vitreous seeding in metastatic cutaneous melanoma: Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04315-5Vitreous seeding in metastatic cutaneous melanoma #Ophthalmology #Eye #Ophthotwitter
Vitreous seeding in metastatic cutaneous melanoma
Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04315-5Vitreous seeding in metastatic cutaneous melanoma
dlvr.it
February 19, 2026 at 7:33 PM
Ophthopedia Update: Focal scleral nodule presenting as a depigmented lesion: Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04299-2Focal scleral nodule presenting as a depigmented lesion #Ophthalmology #Eye #Ophthotwitter
Focal scleral nodule presenting as a depigmented lesion
Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04299-2Focal scleral nodule presenting as a depigmented lesion
dlvr.it
February 19, 2026 at 7:33 PM
Ophthopedia Update: Dropless cataract surgery: comparing sub-Tenon’s and topical steroids for postoperative inflammation prophylaxis: Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04309-3Dropless cataract surgery: comparing sub-Tenon’s and… #Ophthalmology #Eye #Ophthotwitter
Dropless cataract surgery: comparing sub-Tenon’s and topical steroids for postoperative inflammation prophylaxis
Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04309-3Dropless cataract surgery: comparing sub-Tenon’s and topical steroids for postoperative inflammation prophylaxis
dlvr.it
February 19, 2026 at 7:33 PM
Ophthopedia Update: Differentiation of macular atrophy secondary to neovascular age-related macular degeneration vs. de novo geographic atrophy: a multimodal analysis: Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04331-5Differentiation of… #Ophthalmology #Eye #Ophthotwitter
Differentiation of macular atrophy secondary to neovascular age-related macular degeneration vs. de novo geographic atrophy: a multimodal analysis
Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04331-5Differentiation of macular atrophy secondary to neovascular age-related macular degeneration vs. de novo geographic atrophy: a multimodal analysis
dlvr.it
February 19, 2026 at 7:33 PM
Ophthopedia Update: Correlation between blood glucose levels and endophthalmitis risk after intravitreal injections of anti-vascular endothelial growth factor: Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04303-9Correlation between blood… #Ophthalmology #Eye #Ophthotwitter
Correlation between blood glucose levels and endophthalmitis risk after intravitreal injections of anti-vascular endothelial growth factor
Eye, Published online: 19 February 2026; doi:10.1038/s41433-026-04303-9Correlation between blood glucose levels and endophthalmitis risk after intravitreal injections of anti-vascular endothelial growth factor
dlvr.it
February 19, 2026 at 7:33 PM
Ophthopedia Update: VIDEO: Real-world data on aflibercept 8 mg expected in 2026: WAIKOLOA, Hawaii — In this expert perspective from Retina 2026, Murtaza K. Adam, MD, of Colorado Retina Associates, discusses real-world data coming in 2026.
He said he is excited about… #ophthalmology #eye #eyenews
VIDEO: Real-world data on aflibercept 8 mg expected in 2026
WAIKOLOA, Hawaii — In this expert perspective from Retina 2026, Murtaza K. Adam, MD, of Colorado Retina Associates, discusses real-world data coming in 2026. He said he is excited about data on Eylea HD (aflibercept 8 mg, Regeneron). Adam said there is already “robust” real-world data on Vabysmo (faricimab-svoa, Genentech) in neovascular age-related macular degeneration and diabetic macular edema, and “we are looking forward to seeing how the second-generation molecules altogether fare and compare to one another.”
dlvr.it
February 19, 2026 at 6:25 PM
Ophthopedia Update: JAMA Ophthalmology: Mission Statement: To be the indispensable source of ophthalmic knowledge by promptly publishing innovative, clinically relevant research through consistent and authoritative peer review and, thereby, to be the first choice of… #Ophthalmology #Eyecare #JAMA
JAMA Ophthalmology
Mission Statement: To be the indispensable source of ophthalmic knowledge by promptly publishing innovative, clinically relevant research through consistent and authoritative peer review and, thereby, to be the first choice of authors for their important manuscripts.
dlvr.it
February 19, 2026 at 5:49 PM
Ophthopedia Update: Unmasking a Masquerade of Ocular Dysgenesis: A 66-year-old man had nebulomacular corneal opacities, iris atrophy, and corectopia along with coarse facial skin, resorbed digits, anesthetic patches, and healed trophic skin ulcers. What would you do… #Ophthalmology #Eyecare #JAMA
Unmasking a Masquerade of Ocular Dysgenesis
A 66-year-old man had nebulomacular corneal opacities, iris atrophy, and corectopia along with coarse facial skin, resorbed digits, anesthetic patches, and healed trophic skin ulcers. What would you do next?
dlvr.it
February 19, 2026 at 5:49 PM
Ophthopedia Update: Pediatric Orbital MALT Lymphoma Masquerading as a Pyogenic Granuloma: This case report discusses a diagnosis of B-cell lymphoma mucosa-associated lymphoid tissue (MALT) in the conjunctiva of a young boy who presented with a painless, enlarging… #Ophthalmology #Eyecare #JAMA
Pediatric Orbital MALT Lymphoma Masquerading as a Pyogenic Granuloma
This case report discusses a diagnosis of B-cell lymphoma mucosa-associated lymphoid tissue (MALT) in the conjunctiva of a young boy who presented with a painless, enlarging conjunctival mass.
dlvr.it
February 19, 2026 at 5:49 PM
Ophthopedia Update: Ophthalmology Residency Match Rates by Applicant Demographics: This cohort study assesses patterns in medical school students who matched with ophthalmology residency programs from 2021 to 2023, according to candidates’ sex, race, and ethnicity. #Ophthalmology #Eyecare #JAMA
Ophthalmology Residency Match Rates by Applicant Demographics
This cohort study assesses patterns in medical school students who matched with ophthalmology residency programs from 2021 to 2023, according to candidates’ sex, race, and ethnicity.
dlvr.it
February 19, 2026 at 5:49 PM
Ophthopedia Update: Influence of Intraocular Pressure on Clinical Decision-Making in Glaucoma Management: This cohort study using data from the Sight Outcomes Research Collaborative (SOURCE) data repository assesses how intraocular pressure levels influence the… #Ophthalmology #Eyecare #JAMA
Influence of Intraocular Pressure on Clinical Decision-Making in Glaucoma Management
This cohort study using data from the Sight Outcomes Research Collaborative (SOURCE) data repository assesses how intraocular pressure levels influence the decision to initiate or escalate glaucoma therapy in clinical practice.
dlvr.it
February 19, 2026 at 5:49 PM
Ophthopedia Update: Proteomic Profile in Retinopathy of Prematurity: This secondary analysis of the Mega Donna Mega (MDM) randomized clinical trial investigated if early longitudinal changes in proteomic profiles in extremely preterm infants are associated with the… #Ophthalmology #Eyecare #JAMA
Proteomic Profile in Retinopathy of Prematurity
This secondary analysis of the Mega Donna Mega (MDM) randomized clinical trial investigated if early longitudinal changes in proteomic profiles in extremely preterm infants are associated with the development of severe retinopathy of prematurity.
dlvr.it
February 19, 2026 at 5:49 PM
Ophthopedia Update: Iris-Derived Central Corneal Neovascularization in Peters Anomaly: This case report describes a case of Peters anomaly with central corneal neovascularization diagnosed in a female toddler who presented with acute intracorneal hemorrhage in the… #Ophthalmology #Eyecare #JAMA
Iris-Derived Central Corneal Neovascularization in Peters Anomaly
This case report describes a case of Peters anomaly with central corneal neovascularization diagnosed in a female toddler who presented with acute intracorneal hemorrhage in the right eye.
dlvr.it
February 19, 2026 at 5:46 PM