Maria Nattestad 🧬💻
banner
omgenomics.com
Maria Nattestad 🧬💻
@omgenomics.com
Co-founder OMGenomics Labs. Creator of Circa https://circa.omgenomics.com, Ribbon, YouTube.com/omgenomics. Worked on DeepVariant+DeepConsensus at Google.
Reposted by Maria Nattestad 🧬💻
Just published an interactive article about a magical algorithm known as the Burrows-Wheeler Transform, which powers sequence alignment tools like bowtie and bwa: sandbox.bio/concepts/bwt

It's also notoriously unintuitive so I'm hoping this article helps you build that intuition.
October 9, 2025 at 5:05 PM
Reposted by Maria Nattestad 🧬💻
There's now a race to apply AI to every imaginable field of biology. The problem is: unless you understand the biology really well, it's easy to think you've solved the problem when you haven't even come close.

youtu.be/o097zC7CM5I
AI in biology: distinguishing hype from reality
YouTube video by OMGenomics
youtu.be
August 13, 2025 at 4:00 PM
Reposted by Maria Nattestad 🧬💻
We always tell people to create a portfolio to showcase their work, so today we're releasing a template to get you started: github.com/omgenomics/p...

It's made for scientists & engineers who want a living resume that showcases projects, work timeline, and blog posts that demonstrate your expertise
April 15, 2025 at 5:03 PM
We just released a new video on how to get more out of those “let’s chat” conversations when job hunting, based partly on my past experiences being on the receiving end of requests for advice and job referrals:

youtu.be/bpQaIvqqkKw
You might be networking wrong
YouTube video by OMGenomics
youtu.be
February 12, 2025 at 11:13 PM
🧬🖥️ We are hosting free bioinformatics office hours on Feb 19th at 10am-noon PST. Bring your bioinformatics career or technical questions, and @robert.bio and I will try to answer them.
Sign up here: tally.so/r/mOb6dM
Please share especially with students and early career scientists!
February 10, 2025 at 8:15 PM
Reposted by Maria Nattestad 🧬💻
Friends are looking for jobs. Collaborators are dropping off papers. Funds are being pulled away. But let’s just pretend everything is normal.
February 7, 2025 at 4:27 AM
Reposted by Maria Nattestad 🧬💻
🎁 New RNA-Seq tutorial! Learn to run differential expression analysis with DESeq2, and create your own bioinformatics projects using public data and the Expression Atlas 🧬 🖥️

youtu.be/NGbZmlGLG5w
RNA-seq tutorial with DESeq2: Differential gene expression project
YouTube video by OMGenomics
youtu.be
December 17, 2024 at 11:17 PM
I'm working on a little feature for Circa. It's been over a month since I really coded with all the other startup things like marketing and "strategic thinking" taking up my brain space, so it's really nice just to sit down and code a little algorithm and some SVG paths for overlap-avoiding text.
December 10, 2024 at 10:42 PM
Reposted by Maria Nattestad 🧬💻
I made a little swiss army knife tool for quickly inspecting FASTA/FASTQ sequences, including GC content, codon analysis, reverse complement, and file format conversions: 🖥️ 🧬

42basepairs.com/tools/sequen...
Sequence Analysis - 42basepairs
Bioinformatics sequence analysis on FASTA and FASTQ files, including reverse complement, GC content calculations, codon usage analysis, and converting your files to FASTA, FASTQ, or SAM format
42basepairs.com
November 27, 2024 at 7:35 PM
🧬 🖥️ This was a fun one to make: We reviewed 10 CVs sent in by our audience, and here are the 7 common mistakes we kept seeing: youtu.be/qXPJpnrfX_4
We reviewed 10 of our subscribers' CVs!
YouTube video by OMGenomics
youtu.be
November 22, 2024 at 6:28 PM
Reposted by Maria Nattestad 🧬💻
We just released 8 new data wrangling tutorials for biologists! sandbox.bio/community/da... 💻 🧬
Data and Text Processing
Command-line tutorials on data and text processing, by Francisco M. Couto.
sandbox.bio
November 15, 2024 at 5:28 PM
Check out this 1-minute mini-tutorial for Circa 2.0
youtu.be/e_zjPY2vpaM
How to make this circos plot in 1 minute
YouTube video by OMGenomics
youtu.be
November 14, 2024 at 4:27 PM
Reposted by Maria Nattestad 🧬💻
If you think bioinformatics is hard today, you should have seen it in 1985 😬 🧬 🖥️
November 11, 2024 at 5:28 PM
Investigating structural variants? I just released a tutorial video showing how I do this quickly and intuitively using my tools Ribbon and SplitThreader:
youtu.be/TP-H9epbsTM
#bioinformatics
How to investigate structural variants
YouTube video by OMGenomics
youtu.be
November 7, 2024 at 5:11 PM
Here are 3 ways I made money on the side with bioinformatics during my PhD:
www.youtube.com/watch?v=Q64t...
3 ways I made money on the side with bioinformatics
YouTube video by OMGenomics
www.youtube.com
October 25, 2024 at 5:27 PM
Reposted by Maria Nattestad 🧬💻
The backstory behind the FASTA bioinformatics format

🧬🖥️

youtu.be/7LA0IKsVloU?... via @YouTube
youtu.be
October 18, 2024 at 2:40 PM
Reposted by Maria Nattestad 🧬💻
Wait, why aren’t folks using their own domains. Am I missing something?
September 18, 2023 at 6:20 AM