Nicolae Sapoval
@nsapoval.bsky.social
Lost in between mathematics, computer science and biology. Hoping to find myself one day.
https://nsapoval.github.io/
https://nsapoval.github.io/
Check out our new preprint on improving gene regulatory network inference by incorporating a prior from plain-text gene descriptions. It's a simple idea, but we show that it proves to be quite powerful and adaptable. [1/4]
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
GRNITE: Gene Regulatory Network Inference with Text Embeddings
Gene regulatory networks (GRNs) capture complex regulatory relationships that govern gene expression in cells. Inference of GRNs from single-cell RNA-seq (scRNA-seq) data has been an active topic of r...
www.biorxiv.org
November 28, 2025 at 9:49 PM
Check out our new preprint on improving gene regulatory network inference by incorporating a prior from plain-text gene descriptions. It's a simple idea, but we show that it proves to be quite powerful and adaptable. [1/4]
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Nicolae Sapoval
Nicolae Sapoval @nsapoval.bsky.social presented "Theoretical and empirical performance of pseudo-likelihood- based Bayesian inference of species trees under the multispecies coalescent"
A fantastic theory talk, offering intuitive insights!
Paper: doi.org/10.1101/2025.01.28.635282
A fantastic theory talk, offering intuitive insights!
Paper: doi.org/10.1101/2025.01.28.635282
November 6, 2025 at 8:28 PM
Nicolae Sapoval @nsapoval.bsky.social presented "Theoretical and empirical performance of pseudo-likelihood- based Bayesian inference of species trees under the multispecies coalescent"
A fantastic theory talk, offering intuitive insights!
Paper: doi.org/10.1101/2025.01.28.635282
A fantastic theory talk, offering intuitive insights!
Paper: doi.org/10.1101/2025.01.28.635282
Our preprint on using pseudo-likelihood for Bayesian inference of species trees from gene tree data under the multispecies coalescent is now online: doi.org/10.1101/2025...
[1/n]
[1/n]
Theoretical and Empirical Performance of Pseudo-likelihood-based Bayesian Inference of Species Trees under the Multispecies Coalescent
Likelihood-based inference under the multispecies coalescent provides accurate estimates of species trees. However, maximum likelihood and Bayesian inference are both computationally very demanding. P...
doi.org
February 2, 2025 at 12:11 AM
Our preprint on using pseudo-likelihood for Bayesian inference of species trees from gene tree data under the multispecies coalescent is now online: doi.org/10.1101/2025...
[1/n]
[1/n]
It’s that time of the year when I get some writing done. Here are some notes on how I work with academic literature: plume-lifeboat-00b.notion.site/How-I-find-o...
How I find, organize, and read papers | Notion
Introduction
plume-lifeboat-00b.notion.site
January 1, 2025 at 6:48 PM
It’s that time of the year when I get some writing done. Here are some notes on how I work with academic literature: plume-lifeboat-00b.notion.site/How-I-find-o...
I just completed "Ceres Search" - Day 4 - Advent of Code 2024 #AdventOfCode adventofcode.com/2024/day/4 (A little bit behind the schedule this year, but gotta keep it going)
Day 4 - Advent of Code 2024
adventofcode.com
December 5, 2024 at 7:19 PM
I just completed "Ceres Search" - Day 4 - Advent of Code 2024 #AdventOfCode adventofcode.com/2024/day/4 (A little bit behind the schedule this year, but gotta keep it going)
Reposted by Nicolae Sapoval
I was waiting for a great topic for my first Bluesky post, and I cannot thing of a better one: I’m thrilled to be hosting @aphillippy.bsky.social at Rice University today and looking forward to his talk at 4pm! events.rice.edu/event/345896...
Distinguished Lecture: Dr. Adam Phillippy
A Ken Kennedy Institute Distinguished Lecture by Dr. Adam Phillippy, Senior Investigator at National Human Genome Research Institute, National Inst...
events.rice.edu
November 14, 2023 at 3:59 PM
I was waiting for a great topic for my first Bluesky post, and I cannot thing of a better one: I’m thrilled to be hosting @aphillippy.bsky.social at Rice University today and looking forward to his talk at 4pm! events.rice.edu/event/345896...