Noa Matosevich
nmatosevich.bsky.social
Noa Matosevich
@nmatosevich.bsky.social
Neuroscientist, doing my PhD @labnir.bsky.social || Interested in sleep, the LC and norepinephrine.
My PhD paper is finally out! 🎉 We show how specific LC pathways shape sound-evoked awakening, revealing LC heterogeneity in action.
So grateful to all the amazing people who made this possible 🙌
🚨 New paper alert! 🚨(1/6)

Excited to share our work, out now in Science Advances

We show that a rapid norepinephrine surge along a brainstem pathway (LC→PRN) is a key driver of sound-evoked awakenings
www.science.org/doi/10.1126/...
An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening
The locus coeruleus has a specialized pathway to the brainstem that controls sound-evoked awakening from sleep.
www.science.org
September 10, 2025 at 6:36 PM
Reposted by Noa Matosevich
AAV1 hSyn-PdCO-mScarlet-WPRE is finally available from @addgene.bsky.social 🧪🧠

All resources here:
docs.google.com/spreadsheets...
PdCO resources
docs.google.com
February 12, 2025 at 9:22 AM
Excited to share our new preprint out on biorxiv! We found a specific LC pathway that influences sensory evoked awakenings from NREM sleep. @labnir.bsky.social #bluespot 🔵
www.biorxiv.org/content/10.1...
An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening
The locus coeruleus norepinephrine (LC-NE) system regulates arousal and awakening; however, it remains unclear whether the LC does this in a global or circuit specific manner. We hypothesized that sen...
www.biorxiv.org
February 3, 2025 at 8:24 PM