Nikki Lytle
@nikkilytle.bsky.social
Assistant Professor at the Medical College of Wisconsin. Tumor-microenvironment interactions and cell plasticity. Sources of joy: science, dogs, nature, comedy, sports
Reposted by Nikki Lytle
🥳🚨🚨🚨Happy Monday! First publication from the lab is out! My PhD student Md Al Azim reviewed the complexity of ECM, its receptors and their role in cancer progression and therapeutic interventions! We thank Ryan Petrie for his valuable input,our reviewers and Matrix Biology for publishing our work!
April 14, 2025 at 11:32 AM
🥳🚨🚨🚨Happy Monday! First publication from the lab is out! My PhD student Md Al Azim reviewed the complexity of ECM, its receptors and their role in cancer progression and therapeutic interventions! We thank Ryan Petrie for his valuable input,our reviewers and Matrix Biology for publishing our work!
Reposted by Nikki Lytle
@standupforscience.bsky.social Madison. Take home message = call your representatives!!
March 7, 2025 at 10:23 PM
@standupforscience.bsky.social Madison. Take home message = call your representatives!!
Reposted by Nikki Lytle
I'm thrilled to share our latest research, published in Nature Communications. This work highlights how pancreatic cancer cells hijack cell polarity proteins to regulate macropinocytosis and tumor metabolism, shedding light on potential therapeutic vulnerabilities.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Cell polarity proteins promote macropinocytosis in response to metabolic stress - Nature Communications
Cancer cells rely on macropinocytosis to survive in a nutrient-deprived environment. Here, Lambies et al. identified various members of the cell polarity protein network as essential regulators of mac...
www.nature.com
December 4, 2024 at 12:52 AM
I'm thrilled to share our latest research, published in Nature Communications. This work highlights how pancreatic cancer cells hijack cell polarity proteins to regulate macropinocytosis and tumor metabolism, shedding light on potential therapeutic vulnerabilities.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nikki Lytle
Single-cell RNA-sequencing of human spleens reveals an IDO-1+ Tolerogenic Dendritic Cell subset in pancreatic cancer patients that is absent in normal individuals. #PDAC www.sciencedirect.com/science/arti...
Single-cell RNA-sequencing of human spleens reveals an IDO-1+ Tolerogenic Dendritic Cell subset in pancreatic cancer patients that is absent in normal individuals.
Local and systemic immunosuppression are prominent features of pancreatic cancer, rendering anti-tumor effector cells inactive and immunotherapeutic a…
www.sciencedirect.com
November 15, 2024 at 9:17 PM
Single-cell RNA-sequencing of human spleens reveals an IDO-1+ Tolerogenic Dendritic Cell subset in pancreatic cancer patients that is absent in normal individuals. #PDAC www.sciencedirect.com/science/arti...
Reposted by Nikki Lytle
I’m thrilled to share the Pancreatic Cancer Starter Pack! If you want to join DM go.bsky.app/2FHVVL6
November 15, 2024 at 12:15 PM
I’m thrilled to share the Pancreatic Cancer Starter Pack! If you want to join DM go.bsky.app/2FHVVL6