Nihar Desai MD, DM
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nihardesai7.bsky.social
Nihar Desai MD, DM
@nihardesai7.bsky.social
Bone marrow transplant physician at the Princess Margaret Cancer Center, Toronto • Love wildlife, classic rock, and common sense medicine • Follow to learn hematology ❤

@nihardesai89 on that Elon app 🤷🏼
Reposted by Nihar Desai MD, DM
A bit of a #HumbleBrag
The Hans Messner AlloBMT program @hansbmt.bsky.social just infused the 200th allograft of this fiscal year. A new record for us and for Canada! #bmtsm
@tomam04.bsky.social @nihardesai7.bsky.social @uhnresearch.bsky.social
March 25, 2025 at 1:02 AM
Central venous catheter and thrombosis!
March 16, 2025 at 7:05 PM
Reviewer 2 walking away after destroying the manuscript 😭😭
March 5, 2025 at 4:02 AM
This 35 yr old man is always tired 😭

You find 👇🏽 on clinical examination. He also has bradycardia 🫀

Ddx?
Management?

📸 @nejm.org
February 19, 2025 at 2:13 AM
Out now in Blood Advances 🙌🏽

Our work from Princess Margaret Cancer Centre evaluating the role of PTCy in matched sibling donor allogeneic transplantation!

Also read this excellent commentary by my good friend @nicogagelmann.bsky.social 👇🏽

ashpublications.org/bloodadvance...
February 12, 2025 at 4:41 AM
I am pleased to present 3 posters and chair a session at the EBMT annual meeting in Florence 🙌🏽

@hansbmt.bsky.social
February 7, 2025 at 9:14 PM
What doesn’t evolve, goes extinct!!

If you don’t adapt new data, you’ll never improve patient care. No study is perfect, and none ever will be. What matters is critical appraisal of available literature and adapting it to improve patient care 🙏🏽
February 5, 2025 at 2:41 AM
Can a D-dimer be used to diagnose DVT/PE?

NOOOOOOOOOOOOOOOOOOOO!

What else ⤴️D-dimer?
•Any infection
•Any inflammation
•Old age
•Cancer

Remember, D-dimer is a very sensitive test but NOT a very specific test 🙌🏽
February 5, 2025 at 2:39 AM
Anemia in CKD 👇🏽

We all know that CKD = ⤵️EPO

What's the mechanism?

The interstitial cells transdifferentiate into MYOFIBROBLASTS instead of EPO producing cells

⤵️ EPO producing cells = ⤵️EPO = Anemia 👇🏽
February 2, 2025 at 3:18 PM
Fever + cytopenias + organomegaly ➡️ think HLH!

If you don't suspect HLH, you'll miss HLH 🙌🏽

Nice figure by Nguyen et al 👇🏽

doi.org/10.1038/s122...
January 31, 2025 at 1:23 PM
The magic of stem cell transplantation for aplastic anemia 💪🏽

Before ➡️ After
January 14, 2025 at 4:33 AM
📢 Happy to speak about the impact of ABO status on engraftment and survival after allogeneic transplant in the PTCy era at the Cochin Hematology Group annual meeting 🙌🏽
January 13, 2025 at 5:04 AM
Ivermectin is a great drug for parasitic infections but it does NOT cure cancer.

Sincerely,
An oncologist
January 13, 2025 at 5:02 AM
Reposted by Nihar Desai MD, DM
In a single-group, single-center study, clearance of driver mutations 30 days after bone marrow transplantation predicted long-term disease-free survival in patients with myelofibrosis. Read the full study results: nej.md/4fQNdKn

#MedSky
Clearance of Driver Mutations after Transplantation for Myelofibrosis | NEJM
Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation cl...
nej.md
January 10, 2025 at 2:12 PM
Reposted by Nihar Desai MD, DM
I do feel like we forget that a mere 100 years ago 20% of children in America just fucking died.
January 11, 2025 at 4:15 AM
Now that the USA sucks, have you considered moving to USB?
January 10, 2025 at 3:49 AM
Remember, the mentor - mentee relationship is a two way street. Mentees must learn to deliver what they've promised 🙌🏽
January 10, 2025 at 3:47 AM
A mentor need not be your Prof. It could be anyone! A person you meet online, a friend, a senior colleague. It's also possible to have multiple mentors 🙏🏽
January 10, 2025 at 3:47 AM
I ❤️ road trips!
January 5, 2025 at 3:31 AM
Walking in to 2025 with my ❤️
January 2, 2025 at 4:27 AM
I think vaccines had something to do with this 🤷🏼
December 17, 2024 at 3:57 AM
One cannot manage a patient with febrile neutropenia without having a sound knowledge of medicine!

You need to know medicine before you step into a hematology unit! Period.

#MedSky / #SkyMed
December 17, 2024 at 3:51 AM