Nídia S. Trovão, PhD
@nidiatrovao.bsky.social
Lead of GEEP at NIH/FIC | Phylodynamics | Bayesian inference | Viral evolution | Disease ecology | Views are my own
Thrilled to share our new paper where we sequenced 20 new #dengue virus genomes from #SaudiArabia, revealing the country as a major hub for DENV introductions from Asia & Africa and subsequent spread. 🦟🔬
Read it here: www.sciencedirect.com/science/arti...
Read it here: www.sciencedirect.com/science/arti...
Redirecting
doi.org
September 4, 2025 at 10:09 PM
Thrilled to share our new paper where we sequenced 20 new #dengue virus genomes from #SaudiArabia, revealing the country as a major hub for DENV introductions from Asia & Africa and subsequent spread. 🦟🔬
Read it here: www.sciencedirect.com/science/arti...
Read it here: www.sciencedirect.com/science/arti...
Excited to share our new paper on the evolution and spatio-temporal patterns of #hMPV in #CotedIvoire, revealing multiple introductions and widespread transmission. Understanding hMPV is crucial for #publichealth and vaccine development. Read more here: pubmed.ncbi.nlm.nih.gov/40898134/
Repeated introductions and widespread transmission of human metapneumovirus in Côte d'Ivoire - PubMed
In Cote d'Ivoire, the incidence rate of acute respiratory infections (ARIs) rose from 165 cases per 1000 children in 2014 to more than 200 cases per 1000 children in 2015. The genetic diversity, trans...
pubmed.ncbi.nlm.nih.gov
September 4, 2025 at 6:00 PM
Excited to share our new paper on the evolution and spatio-temporal patterns of #hMPV in #CotedIvoire, revealing multiple introductions and widespread transmission. Understanding hMPV is crucial for #publichealth and vaccine development. Read more here: pubmed.ncbi.nlm.nih.gov/40898134/
Reposted by Nídia S. Trovão, PhD
After 8 months of peer review, our manuscript was published today @nature.com showing that bovine H5N1 viruses bind poorly to human-type sialic acid receptors. We now know that the virus is only 1 HA substitution away from efficiently binding human receptors.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Bovine H5N1 binds poorly to human-type sialic acid receptors - Nature
Nature - Bovine H5N1 binds poorly to human-type sialic acid receptors
www.nature.com
April 16, 2025 at 6:40 PM
After 8 months of peer review, our manuscript was published today @nature.com showing that bovine H5N1 viruses bind poorly to human-type sialic acid receptors. We now know that the virus is only 1 HA substitution away from efficiently binding human receptors.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nídia S. Trovão, PhD
#USDA confirmed 5 new #H5N1 #birdflu infected dairy herds in Idaho, bringing the state's total to 52 and the cumulative national total to 1,005 herds in 17 states. www.aphis.usda.gov/livestock-po...
April 9, 2025 at 12:31 PM
#USDA confirmed 5 new #H5N1 #birdflu infected dairy herds in Idaho, bringing the state's total to 52 and the cumulative national total to 1,005 herds in 17 states. www.aphis.usda.gov/livestock-po...
Reposted by Nídia S. Trovão, PhD
seeing all these cruise ship outbreak posts. Interesting to see this phase 3 clinical trial as well! www.nihr.ac.uk/news/uks-fir... . Now norovirus infection is nasty but for normally healthy persons a few days nuisance. Infections can however be severe in persons with impaired immunity
www.nihr.ac.uk
April 4, 2025 at 6:08 PM
seeing all these cruise ship outbreak posts. Interesting to see this phase 3 clinical trial as well! www.nihr.ac.uk/news/uks-fir... . Now norovirus infection is nasty but for normally healthy persons a few days nuisance. Infections can however be severe in persons with impaired immunity
Reposted by Nídia S. Trovão, PhD
Cant wait to give this a spin: FluMut, an open-source, cross-platform tool designed to identify molecular markers for host adaptation, increased virulence, and antiviral resistance in H5N1 viruses
👉 academic.oup.com/ve/article/1...
👉 academic.oup.com/ve/article/1...
March 16, 2025 at 11:15 PM
Cant wait to give this a spin: FluMut, an open-source, cross-platform tool designed to identify molecular markers for host adaptation, increased virulence, and antiviral resistance in H5N1 viruses
👉 academic.oup.com/ve/article/1...
👉 academic.oup.com/ve/article/1...
Reposted by Nídia S. Trovão, PhD
Cheese produced from raw milk: pH-dependent survival of HPAI, with infectious virus persisting throughout the cheese making process and for up to 60 days of aging in the pH 6.6 and 5.8 cheese groups. At pH 5.0, no virus survival.
👉 www.biorxiv.org/content/10.1...
👉 www.biorxiv.org/content/10.1...
March 16, 2025 at 11:32 PM
Cheese produced from raw milk: pH-dependent survival of HPAI, with infectious virus persisting throughout the cheese making process and for up to 60 days of aging in the pH 6.6 and 5.8 cheese groups. At pH 5.0, no virus survival.
👉 www.biorxiv.org/content/10.1...
👉 www.biorxiv.org/content/10.1...
Reposted by Nídia S. Trovão, PhD
How a fat in our diet (omega-6 linoleic acid)—a dietary long-chain polyunsaturated fatty acid) has the potential to promote tumor growth www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
@science.org
www.science.org/doi/10.1126/...
@science.org
March 13, 2025 at 7:54 PM
How a fat in our diet (omega-6 linoleic acid)—a dietary long-chain polyunsaturated fatty acid) has the potential to promote tumor growth www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
@science.org
www.science.org/doi/10.1126/...
@science.org
Reposted by Nídia S. Trovão, PhD
new genotype H5N1 introduced around December 2024, > a month before first measures were taken, despite testing of milk samples. Authors call for more vigorous testing for timely and maximally effective control measures for bovine H5N1 outbreaks virological.org/t/timing-and...
Timing and molecular characterisation of the transmission to cattle of H5N1 influenza A virus genotype D1.1, clade 2.3.4.4b
Jonathan E. Pekar, Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, UK Thomas P. Peacock, The Pirbright Institute, Woking, UK, GU24 0NF; Department of Infectious Disease, Imper...
virological.org
February 23, 2025 at 5:35 PM
new genotype H5N1 introduced around December 2024, > a month before first measures were taken, despite testing of milk samples. Authors call for more vigorous testing for timely and maximally effective control measures for bovine H5N1 outbreaks virological.org/t/timing-and...
Reposted by Nídia S. Trovão, PhD
Bird flu spreads to marine mammals in UK : www.theguardian.com/environment/...
Four seals die on Norfolk coast after contracting bird flu
Experts raise fears for England’s largest colony at Blakeney Point as they conduct tests to identify source of infection
www.theguardian.com
February 19, 2025 at 7:24 PM
Bird flu spreads to marine mammals in UK : www.theguardian.com/environment/...
Reposted by Nídia S. Trovão, PhD
#RSV vaccine prompts robust immune response in older recipients over 2 seasons
The vaccine had a similar favorable safety profile as placebo.
www.cidrap.umn.edu/r...
The vaccine had a similar favorable safety profile as placebo.
www.cidrap.umn.edu/r...
February 17, 2025 at 9:41 PM
#RSV vaccine prompts robust immune response in older recipients over 2 seasons
The vaccine had a similar favorable safety profile as placebo.
www.cidrap.umn.edu/r...
The vaccine had a similar favorable safety profile as placebo.
www.cidrap.umn.edu/r...
Reposted by Nídia S. Trovão, PhD
In toxic cultures, people get promoted for results even if they destroy relationships. Abuse is a price to pay for high performance.
In healthy cultures, no level of individual excellence justifies undermining people. You’re not a high performer if you don't elevate others.
In healthy cultures, no level of individual excellence justifies undermining people. You’re not a high performer if you don't elevate others.
January 22, 2025 at 10:20 PM
In toxic cultures, people get promoted for results even if they destroy relationships. Abuse is a price to pay for high performance.
In healthy cultures, no level of individual excellence justifies undermining people. You’re not a high performer if you don't elevate others.
In healthy cultures, no level of individual excellence justifies undermining people. You’re not a high performer if you don't elevate others.
Reposted by Nídia S. Trovão, PhD
A sick snow goose in West Philly has tested positive for H5N1. This is a very urban/populated area not too far from our lab. It is important for everyone to stay away from sick birds to avoid H5N1 exposures.
www.nbcphiladelphia.com/news/health/...
www.nbcphiladelphia.com/news/health/...
Sick goose is 1st case of bird flu in Philadelphia amid national outbreak
A sick snow goose found in West Philadelphia earlier this month has tested positive for the avian influenza A(H5), making it the first bird in the city to test positive for the highly-pathogenic bird ...
www.nbcphiladelphia.com
January 22, 2025 at 9:10 PM
A sick snow goose in West Philly has tested positive for H5N1. This is a very urban/populated area not too far from our lab. It is important for everyone to stay away from sick birds to avoid H5N1 exposures.
www.nbcphiladelphia.com/news/health/...
www.nbcphiladelphia.com/news/health/...
Reposted by Nídia S. Trovão, PhD
📢Job alert
We have two postdoctoral positions available, starting in Spring 2025. These positions are part of research funded by an ERC Advanced Grant, focused on exploring evolutionary immunology (Evo-Immuno). #Postdoc #InnateImmunity
Do not hesitate to contact us. ibmc.cnrs.fr/en/laboratoi...
We have two postdoctoral positions available, starting in Spring 2025. These positions are part of research funded by an ERC Advanced Grant, focused on exploring evolutionary immunology (Evo-Immuno). #Postdoc #InnateImmunity
Do not hesitate to contact us. ibmc.cnrs.fr/en/laboratoi...
January 17, 2025 at 8:34 AM
📢Job alert
We have two postdoctoral positions available, starting in Spring 2025. These positions are part of research funded by an ERC Advanced Grant, focused on exploring evolutionary immunology (Evo-Immuno). #Postdoc #InnateImmunity
Do not hesitate to contact us. ibmc.cnrs.fr/en/laboratoi...
We have two postdoctoral positions available, starting in Spring 2025. These positions are part of research funded by an ERC Advanced Grant, focused on exploring evolutionary immunology (Evo-Immuno). #Postdoc #InnateImmunity
Do not hesitate to contact us. ibmc.cnrs.fr/en/laboratoi...
Reposted by Nídia S. Trovão, PhD
Bolivia has confirmed a death from a case of Chapare virus identified in December 2024. Thankfully all contacts have tested negative so far. Chapare virus is an arena virus transmitted by rodents. It was discovered in 2003.
www.telegraph.co.uk/global-healt...
www.telegraph.co.uk/global-healt...
Bolivia confirms death from Ebola-like virus so rare only 15 cases have ever been reported
It is still unclear how the farmer contracted Chapare Hemorrhagic Fever, but it is primarily caught through contact with infected rodents
www.telegraph.co.uk
January 22, 2025 at 9:19 PM
Bolivia has confirmed a death from a case of Chapare virus identified in December 2024. Thankfully all contacts have tested negative so far. Chapare virus is an arena virus transmitted by rodents. It was discovered in 2003.
www.telegraph.co.uk/global-healt...
www.telegraph.co.uk/global-healt...
Reposted by Nídia S. Trovão, PhD
Out the first of January:
Integrating dynamical modeling and phylogeographic inference to characterize global influenza circulation
academic.oup.com/pnasnexus/ar...
Integrating dynamical modeling and phylogeographic inference to characterize global influenza circulation
academic.oup.com/pnasnexus/ar...
Integrating dynamical modeling and phylogeographic inference to characterize global influenza circulation
Abstract. Global seasonal influenza circulation involves a complex interplay between local (seasonality, demography, host immunity) and global factors (int
academic.oup.com
January 7, 2025 at 9:44 AM
Out the first of January:
Integrating dynamical modeling and phylogeographic inference to characterize global influenza circulation
academic.oup.com/pnasnexus/ar...
Integrating dynamical modeling and phylogeographic inference to characterize global influenza circulation
academic.oup.com/pnasnexus/ar...
Reposted by Nídia S. Trovão, PhD
Health officials in Louisiana say a person there has died after catching bird flu. This marks the first reported death in the U.S. from the virus during the current outbreak.
First bird flu death reported in the U.S., according to the CDC
Health officials in Louisiana say a person there has died after catching bird flu. This marks the first reported death in the U.S. from the virus during the current outbreak.
www.npr.org
January 7, 2025 at 12:46 AM
Health officials in Louisiana say a person there has died after catching bird flu. This marks the first reported death in the U.S. from the virus during the current outbreak.
Reposted by Nídia S. Trovão, PhD
I really need a better hobby, but I've enabled a new H5N1 dashboard view to let you see how known outbreaks/detections may interact with USDA Ag Census (2022) livestock inventories for:
• 🐔 Poultry
• 🐷 Pigs/Hogs
• 🐄 Dairy Cattle
• 🐮 Beef Cattle
Select the new "USDA" tab:
bit.ly/H5N1_Dashboard
• 🐔 Poultry
• 🐷 Pigs/Hogs
• 🐄 Dairy Cattle
• 🐮 Beef Cattle
Select the new "USDA" tab:
bit.ly/H5N1_Dashboard
January 1, 2025 at 5:27 PM
I really need a better hobby, but I've enabled a new H5N1 dashboard view to let you see how known outbreaks/detections may interact with USDA Ag Census (2022) livestock inventories for:
• 🐔 Poultry
• 🐷 Pigs/Hogs
• 🐄 Dairy Cattle
• 🐮 Beef Cattle
Select the new "USDA" tab:
bit.ly/H5N1_Dashboard
• 🐔 Poultry
• 🐷 Pigs/Hogs
• 🐄 Dairy Cattle
• 🐮 Beef Cattle
Select the new "USDA" tab:
bit.ly/H5N1_Dashboard
Reposted by Nídia S. Trovão, PhD
⚠️ BREAKING:
USDA has confirmed a polar bear infected with H5N1 bird flu in North Slope, Alaska.
USDA has confirmed a polar bear infected with H5N1 bird flu in North Slope, Alaska.
December 13, 2024 at 5:14 PM
⚠️ BREAKING:
USDA has confirmed a polar bear infected with H5N1 bird flu in North Slope, Alaska.
USDA has confirmed a polar bear infected with H5N1 bird flu in North Slope, Alaska.
Reposted by Nídia S. Trovão, PhD
⚠️ BREAKING:
USDA has confirmed a domestic cat infected with H5N1 bird flu in Tulare county, California.
USDA has confirmed a domestic cat infected with H5N1 bird flu in Tulare county, California.
December 13, 2024 at 5:14 PM
⚠️ BREAKING:
USDA has confirmed a domestic cat infected with H5N1 bird flu in Tulare county, California.
USDA has confirmed a domestic cat infected with H5N1 bird flu in Tulare county, California.
Reposted by Nídia S. Trovão, PhD
Investigators trying to determine how a child in California might have contracted H5N1 bird flu are continuing to learn more details about the case.
Case of possible bird flu in California remains murky, and may stay that way
Investigators trying to determine how a child in California might have contracted bird flu are continuing to learn more details about the case.
buff.ly
December 12, 2024 at 3:20 PM
Investigators trying to determine how a child in California might have contracted H5N1 bird flu are continuing to learn more details about the case.
Reposted by Nídia S. Trovão, PhD
Thorough review of avian influenza in human patients: transmission, clinical presentation & complications, diagnosis, treatment, investigational therapies, infection control vaccination.
👉https://doi.org/10.1002/phar.4621
👉https://doi.org/10.1002/phar.4621
December 2, 2024 at 3:46 AM
Thorough review of avian influenza in human patients: transmission, clinical presentation & complications, diagnosis, treatment, investigational therapies, infection control vaccination.
👉https://doi.org/10.1002/phar.4621
👉https://doi.org/10.1002/phar.4621
Reposted by Nídia S. Trovão, PhD
There is still time to register for the seminar by Dr. Trovao @nidiatrovao.bsky.social from NIH/FIC, happening at tomorrow 1 pm EST (in-person and over zoom, open to everyone). Register here: events.columbia.edu/cal/event/ev...
November 25, 2024 at 3:59 PM
There is still time to register for the seminar by Dr. Trovao @nidiatrovao.bsky.social from NIH/FIC, happening at tomorrow 1 pm EST (in-person and over zoom, open to everyone). Register here: events.columbia.edu/cal/event/ev...
Reposted by Nídia S. Trovão, PhD
Welcome to ColumbiaMSPH Dean's Seminar Series on Infectious Disease Modeling featuring @nidiatrovao.bsky.social on Nov 26 (hybrid and open to the public). Register to join over Zoom! For registration: events.columbia.edu/cal/event/ev...
Future events: publichealth.columbia.edu/about-us/eve...
Future events: publichealth.columbia.edu/about-us/eve...
November 19, 2024 at 2:45 PM
Welcome to ColumbiaMSPH Dean's Seminar Series on Infectious Disease Modeling featuring @nidiatrovao.bsky.social on Nov 26 (hybrid and open to the public). Register to join over Zoom! For registration: events.columbia.edu/cal/event/ev...
Future events: publichealth.columbia.edu/about-us/eve...
Future events: publichealth.columbia.edu/about-us/eve...
Reposted by Nídia S. Trovão, PhD
Even if the risk of a pandemic appears low for now, the results are another warning that the U.S. needs to do more to bring H5N1 in cattle under control, says Albert Osterhaus: “Even a low risk of a looming catastrophe should be tackled at the source.”
www.science.org/content/arti...
www.science.org/content/arti...
Many human infections with ‘cow flu’ are going undetected
Scientists find evidence of past H5N1 infection in 7% of workers exposed at dairy farms—but no signs of human-to-human transmission
www.science.org
November 8, 2024 at 2:49 AM
Even if the risk of a pandemic appears low for now, the results are another warning that the U.S. needs to do more to bring H5N1 in cattle under control, says Albert Osterhaus: “Even a low risk of a looming catastrophe should be tackled at the source.”
www.science.org/content/arti...
www.science.org/content/arti...