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myadla.bsky.social
@myadla.bsky.social
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kidneying.bsky.social
#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores

pubmed.ncbi.nlm.nih....
pubmed.ncbi.nlm.nih....

☄️ More than few reported cases exist

July 31, 2025 at 12:55 PM
Reposted
kidneying.bsky.social
ℹ️Turns out patient has hypogammaglobulinemia
❓MMF related/disease related
Ig A - 134 mg/dl ( 70-400)
⬇️Ig G - 669 mg/dL (700-1600)
⬇️⬇️Ig M - 38 mg/dL (40-230)

😏Does it explain all?

#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores
July 31, 2025 at 12:48 PM
Reposted
kidneying.bsky.social
#ECNeph
@brammahin @myadla @Dilushiwijay @acssjr @dra_miliflores
@Dilushiwijay @ISNkidneycare

Admitted with febrile illness
Flare vs infection

Any other DD ?
Thoughts plz !
Mild rise in creatinine
Kidney Bx : Now Class III LN
July 31, 2025 at 12:26 PM
Reposted
kidneying.bsky.social
#ECNeph @brammahin @myadla @ISNkidneycare
@Dilushiwijay @acssjr @dra_miliflores

Class switching in LN
Bomback AS. Nonproliferative Forms of Lupus Nephritis: An Overview. Rheum Dis Clin North Am. 2018 Nov;44(4):561-569
July 31, 2025 at 12:27 PM
Reposted
acssjr.bsky.social
Let start the discussion!
23 YO women with Lupus and recurrent admissions
#ECNeph
@kidneying.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social @dramiliflores.bsky.social
July 31, 2025 at 12:14 PM
myadla.bsky.social
Hi #ECNeph
Dr Manjusha From India
Eager to learn
July 31, 2025 at 12:15 PM
Reposted
kidneying.bsky.social
#ECNeph
@brammahin @myadla @Dilushiwijay @acssjr @dra_miliflores
@Dilushiwijay @ISNkidneycare

Is the diagnosis obvious ?
Should we check labs?
ANA+VE/low C3/hemat /Musculo skeletal involvement /Kidney
Biopsy done in v/o proteinuria : Class 1
Can it be podocytopathy
July 31, 2025 at 12:14 PM
myadla.bsky.social
Thank you for a good case prsentation
@karnephro.bsky.social #ECNeph @dilushiwijay.bsky.social @theisn.org
June 30, 2025 at 5:00 PM
myadla.bsky.social
Recent publication from CKJ
@karnephro.bsky.social #ECNeph @dilushiwijay.bsky.social @theisn.org
June 30, 2025 at 4:59 PM
Reposted
karnephro.bsky.social
⚡️PLA2R antibody seropositivity doesn’t mean that we do not investigate for underlying malignancies.
Here is a Case Report showing PLA2rAb MN having Carcinoma Oesophagus
#ECNeph
@theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social
June 30, 2025 at 4:57 PM
Reposted
karnephro.bsky.social
KDIGO recommends Population and Age-appropriate Screening for malignancies irrespective of antigen status
#ECNeph
@theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social
June 30, 2025 at 4:55 PM
Reposted
theisn.org
Yes, some tests came after biopsy #ECNEPh
June 30, 2025 at 4:39 PM
myadla.bsky.social
@karnephro.bsky.social #ECNeph @dilushiwijay.bsky.social @theisn.org
June 30, 2025 at 4:55 PM
myadla.bsky.social
Check the distribution of solid malignancies in NS
@karnephro.bsky.social #ECNeph @dilushiwijay.bsky.social @theisn.org
June 30, 2025 at 4:54 PM
myadla.bsky.social
Differentiating between PMN and SMN @karnephro.bsky.social #ECNeph @dilushiwijay.bsky.social @theisn.org
June 30, 2025 at 4:49 PM
Reposted
theisn.org
Final Diagnosis
#ECNeph
@dramiliflores.bsky.social @karnephro.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
June 30, 2025 at 4:44 PM
Reposted
karnephro.bsky.social
👉 🫣 Can IF differentiate from Primary and Secondary MN?
IgG 4 is the dominant class in primary MN
👉 IgG1,IgG2, IgG3 are dominant Immunoglobulins in Secondary MN

#ECNeph
@theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social
June 30, 2025 at 4:47 PM
myadla.bsky.social
Paraneoplastic glomerulopathies
@karnephro.bsky.social #ECNeph @dilushiwijay.bsky.social @theisn.org
June 30, 2025 at 4:45 PM
myadla.bsky.social
Some more info about PNS !
@karnephro.bsky.social #ECNeph @dilushiwijay.bsky.social @theisn.org
June 30, 2025 at 4:43 PM
myadla.bsky.social
@karnephro.bsky.social #ECNeph @dilushiwijay.bsky.social @theisn.org
Paraneoplastic glomerulopathy can occur before /sfter or simultaneously with the diagnosis of MN
Need for evaluation of cases of MN for underlying malignancy is suggested
June 30, 2025 at 4:41 PM
Reposted
theisn.org
Primary vs Secondary Membranous Nephropathy #ECNeph
http://springer.com/...
@dramiliflores.bsky.social @karnephro.bsky.social
June 30, 2025 at 4:25 PM
Reposted
theisn.org
🔬 The characteristic histopathologic features of MN, light microscopy, IF, EM, are falling into place.
So… where are we in this case? Granular IgG, GBM thickening, no crescents...
What do you think?
#ECNeph @dramiliflores.bsky.social @karnephro.bsky.social

www.ajkd.org/action/...
June 30, 2025 at 4:27 PM
Reposted
theisn.org
A positive anti-PLA2R antibody test is “virtually” diagnostic of a lesion of MN (but may not always be able to reliably distinguish primary and secondary forms) #ECNeph #MedSky #NephSky @kdjhaveri.bsky.social @dramiliflores.bsky.social @karnephro.bsky.social

June 30, 2025 at 4:29 PM
Reposted
karnephro.bsky.social
Different types of tumor secrete different types of antigen.
Here is the proposed mechanism of malignancy associated MN. #ECneph
@dramiliflores.bsky.social @myadla.bsky.social @theisn.org

www.frontiersin.org/journals/med...
June 30, 2025 at 4:34 PM