Augusto Cesar S Santos Jr
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acssjr.bsky.social
Augusto Cesar S Santos Jr
@acssjr.bsky.social
500 followers 190 following 23 posts
Postdoctoral researcher and nephrologist, driven by science (from the bottom of my kidneys!)
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acssjr.bsky.social
Access the WKD Social Media toolkit and find lots of materials to boost your WKD 2026 campaign.

www.worldkidneyday.org/knowledge-ba...

#KidneyHealthMatters #OurKidneyOurPlanet
#CheckYourCreatinine
#Prevention #Protect #Planet #PublicHealth
@theisn.org
November 2, 2025 at 8:20 PM
acssjr.bsky.social
Check at @transplantation.bsky.social

The bioinformatic tool HLA-EP-RESOLVER accurately predicts antibody reactivity to rare HLA alleles using eplet analysis.

tinyurl.com/2m9nm6ek

#Transplantation #High #Resolution #HLA
October 11, 2025 at 11:15 AM
Reposted by Augusto Cesar S Santos Jr
transplantation.bsky.social
The bioinformatic tool HLA-EP-RESOLVER accurately predicts antibody reactivity to rare HLA alleles using eplet analysis. Validated in sensitized patients, it helps identify acceptable/unacceptable antigens in the era of high-resolution donor typing. #HLA tinyurl.com/2m9nm6ek
October 8, 2025 at 10:27 AM
acssjr.bsky.social
World Kidney Day 2026 starts now!
Participate!

Caring for people, protecting the planet!
#KidneyHealthMatters
#CheckYourCreatinine
theisn.org ISNkidneycare @theisn.org · Sep 15
📣 We’re thrilled for the launch of the World Kidney Day 2026 campaign! We’re loving the new campaign image!

Discover the 2026 theme here 👉 www.worldkidneyday.o...
#WorldKidneyDay #OurKidneysOurPlanet #KidneyHealthForAll
September 16, 2025 at 11:03 AM
acssjr.bsky.social
Just 1 month to go until the 2026 #WKD campaign officially kicks off!

Stay tuned for updates. Get ready to join us in this movement for kidney health!

Follow the @worldkidneyday site and social media pages!
www.worldkidneyday.org

@theisn.org IFKF #KidneyHealthMatters
Homepage - World Kidney Day 2025
World Kidney DayRaising awareness of theimportance of our kidneysWho we areWKD 2025 Scientific EditorialAre Your Kidneys Ok?Detect early to protect kidney healthRead the 2025 Scientific EditorialKidne...
www.worldkidneyday.org
August 15, 2025 at 8:39 PM
acssjr.bsky.social
I’m thrilled to see the Graphical Abstract Video Presentations now featured on the KIR website!

www.kireports.org/video-do

I’m deeply grateful to everyone who contributed to making this #vision a reality!
@theisn.org @kidneyint.bsky.social @kireports.bsky.social

#ThisIsISN #KidneyHealthMatters
August 2, 2025 at 1:50 AM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
#ECNeph @brammahin.@myadla. @Dilushiwijay
@dra_miliflore @acssjr

Similar presentation in Post Tx Pt

But ..why is it so rare ?
Why dont we see it often despite high use ?

Thoughts ?
July 31, 2025 at 12:57 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
Proposed mechanism of hyperinflammation due to MMF
#ECNeph @brammahin @myadla @Dilushiwijay @dra_miliflores
@acssjr.bsky.social
July 31, 2025 at 12:53 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores

⚠️ Few warnings exist already
July 31, 2025 at 12:54 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
When you suspect MMF-hyperinflammation
dont forget to exclude these
#ECNeph @brammahin @myadla @Dilushiwijay
@dra_miliflores
@acssjr.bsky.social
July 31, 2025 at 12:54 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores

pubmed.ncbi.nlm.nih....
pubmed.ncbi.nlm.nih....

☄️ More than few reported cases exist

July 31, 2025 at 12:55 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
Differentiating fever from flare in lupus
#ECNeph @brammahin @myadla @Dilushiwijay
@dra_miliflores @acssjr

NLR
CRP/ESR ratio <2/2-15/>15 : <2 s/o infection
July 31, 2025 at 12:51 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
💥 Could this be MAS in SLE? We are seeing it more often,

🗝️ - Clues in clinical practice
Fever
Pancytopenia
Organomegaly
⬇️ ESR with disease activity

#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores

July 31, 2025 at 12:52 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
ℹ️Turns out patient has hypogammaglobulinemia
❓MMF related/disease related
Ig A - 134 mg/dl ( 70-400)
⬇️Ig G - 669 mg/dL (700-1600)
⬇️⬇️Ig M - 38 mg/dL (40-230)

😏Does it explain all?

#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores
July 31, 2025 at 12:48 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
#ECNeph @brammahin @myadla @Dilushiwijay
@acssjr @dra_miliflores
#ECNeph

Do you agree ?

Post your final diagnosis ....

Is it to do with IST ?
July 31, 2025 at 12:47 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
🦠 When do you think fever is of infection in origin?

⁉️ Can we rule out all infections all the times? Say some hidden TB or a very timid virus. We need more markers.

#ECNeph @brammahin @Dilushiwijay @myadla @acssjr
@dra_miliflores

July 31, 2025 at 12:45 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
#ECNeph @brammahin @myadla @Dilushiwijay
@acssjr @dra_miliflores
#ECNeph
yet another admission ..in a weeks time
premature discharge vs recurrence of infection /appearance of flare

High inflammatory markers favour infection
or is it non infectious inflammation
July 31, 2025 at 12:44 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
#ECNeph @brammahin @myadla @Dilushiwijay
@acssjr @dra_miliflores
#ECNeph

see the time line of admissions for febrile episodes
Class switch
High inflammatory markers
Infection clues negative
3 episodes in 2-3 months

Where should this lead to ?
July 31, 2025 at 12:45 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
🔂 3 admissions with acute febrile illnesses within
2-month span
🩺 No focal signs/symptoms
☢️ Routine imaging -negative -No organ-specific
illness
#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores

July 31, 2025 at 12:42 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
#ECNeph @brammahin @myadla @Dilushiwijay
@acssjr @dra_miliflores
#ECNeph
Rx with antibiotics
Restarted on IST after fever subsidence

What next ?
Evaluation being negative for all infections : Bacteria /virus ..
How to go further ?
July 31, 2025 at 12:43 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
⚓️ What features would suggest SLE activity for you?

⚖️ Do you weigh on global assessment?

#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores

July 31, 2025 at 12:43 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
#ECNeph @brammahin @myadla @ISNkidneycare
@Dilushiwijay @acssjr @dra_miliflores

ESR:CRP <2
S/O infection than flare
Lupus. 2018 Jun;27(7):1123-1129
July 31, 2025 at 12:41 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
#ECNeph @brammahin @myadla @ISNkidneycare @Dilushiwijay @acssjr @dra_miliflores

Does the evaluation suggest flare ?
All atypical infections ruled out
Malignancy ??????
What else ?
PET-CT ?
July 31, 2025 at 12:39 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
🗣️Fever in SLE - An enigma wrapped in mystery.

Interested in hearing your phrases of fever and also how do you define it in routine practice?

🧈 Just basics
#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores
July 31, 2025 at 12:40 PM
Reposted by Augusto Cesar S Santos Jr
kidneying.bsky.social
How to differentiate between flare /Infection in SLE
#ECNeph @brammahin @myadla @Dilushiwijay
@dra_miliflores @acssjr.bsky.social
July 31, 2025 at 12:40 PM