Mukund Sharma
@muksha.bsky.social
postdoc @westermarcklab.bsky.social @turkubioscience.bsky.social exploring #Epigenetic targets for #Cancer therapy
Reposted by Mukund Sharma
You should join, this will be the best meeting of the year :)
Registration is open for our Imaging Cell Dynamics meeting.
Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti, the meeting will focus on the interface between cell biology and imaging.
For more info: www.biologists.com/meetings/jcs...
Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti, the meeting will focus on the interface between cell biology and imaging.
For more info: www.biologists.com/meetings/jcs...
September 15, 2025 at 2:05 PM
You should join, this will be the best meeting of the year :)
Reposted by Mukund Sharma
Thrilled to share our new study from @joycelab.bsky.social on glioblastoma, the most aggressive brain tumor. Targeting ADAR1 slows tumor growth & mobilizes the immune system — a step forward for future treatments. www.sciencedirect.com/science/arti... 🔗 1/3
Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival
Glioblastomas are the most frequent and aggressive primary brain tumors. Current treatments invariably fail, a consequence of the pronounced heterogen…
www.sciencedirect.com
September 4, 2025 at 8:06 AM
Thrilled to share our new study from @joycelab.bsky.social on glioblastoma, the most aggressive brain tumor. Targeting ADAR1 slows tumor growth & mobilizes the immune system — a step forward for future treatments. www.sciencedirect.com/science/arti... 🔗 1/3
Reposted by Mukund Sharma
Elias Tillandz Prize awarded at the BioCity Symposium to scientific publications on breast cancer recurrence and cancer gene overactivation www.utu.fi/en/news/pres...
Elias Tillandz Prize awarded at the BioCity Symposium to scientific publications on breast cancer recurrence and cancer gene overactivation
The Elias Tillandz prize for the best scientific publication of 2024 was presented for two groundbreaking cancer studies.
www.utu.fi
August 28, 2025 at 7:20 AM
Elias Tillandz Prize awarded at the BioCity Symposium to scientific publications on breast cancer recurrence and cancer gene overactivation www.utu.fi/en/news/pres...
Reposted by Mukund Sharma
We are on the cover! Or what is in the cover is way more important than we, it's evidence that simple IHC assay could be used for recognising #HNSCC patients based on their outcome after surgery-only therapy.
The actual cover and the article can be found here:
www.embopress.org/doi/full/10....
The actual cover and the article can be found here:
www.embopress.org/doi/full/10....
August 11, 2025 at 10:50 AM
We are on the cover! Or what is in the cover is way more important than we, it's evidence that simple IHC assay could be used for recognising #HNSCC patients based on their outcome after surgery-only therapy.
The actual cover and the article can be found here:
www.embopress.org/doi/full/10....
The actual cover and the article can be found here:
www.embopress.org/doi/full/10....
Reposted by Mukund Sharma
Particularly proud of this collaboration with Sami Ventela and all Finnish #HNSCC clinics revealing LIMA1-alpha as translatable biomarker for selection of HNSCC patients for surgery-only therapies.
www.utu.fi/en/news/pres...
www.embopress.org/doi/full/10....
www.utu.fi/en/news/pres...
www.embopress.org/doi/full/10....
New diagnostic breakthrough predicts which head and neck cancer patients can be cured with surgery alone
Researchers developed a diagnostic test based on the LIMA1-alpha protein to distinguish patients with head and neck squamous cell carcinoma who can be cured with surgery alone, without the need for
www.utu.fi
July 23, 2025 at 7:42 AM
Particularly proud of this collaboration with Sami Ventela and all Finnish #HNSCC clinics revealing LIMA1-alpha as translatable biomarker for selection of HNSCC patients for surgery-only therapies.
www.utu.fi/en/news/pres...
www.embopress.org/doi/full/10....
www.utu.fi/en/news/pres...
www.embopress.org/doi/full/10....
Reposted by Mukund Sharma
Generate beautiful PDF of your manuscripts easily using Markdown. #RxivMaker is here. We hope it will supercharge your #preprints Mojo.
🧑🔬📰🚀 #RxivMaker is here! A framework automating the creation of publication-ready scientific #preprints from simple Markdown. Goodbye manual formatting, and hello gorgeous manuscripts! A great adventure with @guijacquemet.bsky.social's lab
📜: zenodo.org/records/1575...
👨💻: github.com/HenriquesLab...
📜: zenodo.org/records/1575...
👨💻: github.com/HenriquesLab...
June 27, 2025 at 2:08 PM
Generate beautiful PDF of your manuscripts easily using Markdown. #RxivMaker is here. We hope it will supercharge your #preprints Mojo.
Reposted by Mukund Sharma
Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!
June 23, 2025 at 2:29 PM
Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!
Reposted by Mukund Sharma
Fantastic EACR @helloeacr.bsky.social annual congress in Lisbon. Great talks Great atmosphere Great to meet all old and new friends
June 18, 2025 at 3:40 PM
Fantastic EACR @helloeacr.bsky.social annual congress in Lisbon. Great talks Great atmosphere Great to meet all old and new friends
Reposted by Mukund Sharma
A blood test can detect breast cancer drug resistance, and a combination treatment improves outcomes in colorectal cancer. Learn about these and other stories from Cancer Today magazine's Week in Cancer News. www.cancertodaymag.org/cancer-talk/...
June 6: The Week in Cancer News | Cancer Today
A blood test can detect breast cancer drug resistance, and a combination treatment improves outcomes in colorectal cancer.
www.cancertodaymag.org
June 6, 2025 at 8:03 PM
A blood test can detect breast cancer drug resistance, and a combination treatment improves outcomes in colorectal cancer. Learn about these and other stories from Cancer Today magazine's Week in Cancer News. www.cancertodaymag.org/cancer-talk/...
Reposted by Mukund Sharma
AstraZeneca unveils drug to treat mutating breast cancer before it starts to grow—Professor @helink.bsky.social chief executive of the Institute of Cancer Research, said the results… www.ft.com/content/9c3b... @hannahkuchler.bsky.social @financialtimes.com
AstraZeneca unveils drug to treat mutating breast cancer before it starts to grow
Pharma group estimates Camizestrant could be worth up to $5bn of sales in its peak year
www.ft.com
June 3, 2025 at 12:06 AM
AstraZeneca unveils drug to treat mutating breast cancer before it starts to grow—Professor @helink.bsky.social chief executive of the Institute of Cancer Research, said the results… www.ft.com/content/9c3b... @hannahkuchler.bsky.social @financialtimes.com
Reposted by Mukund Sharma
Absolutely catapulting quadrable WEKK (Westermarck, Elenius, Kurppa, Kauko) retreat @Villa Wolax. Fantastic science, discussions, sauna, food, wine, colleagues @turkubioscience.bsky.social @medicity.bsky.social
June 2, 2025 at 6:22 PM
Absolutely catapulting quadrable WEKK (Westermarck, Elenius, Kurppa, Kauko) retreat @Villa Wolax. Fantastic science, discussions, sauna, food, wine, colleagues @turkubioscience.bsky.social @medicity.bsky.social
Reposted by Mukund Sharma
Delighted that my lab could contribute to this beautiful story by Jukka Westermarck's lab www.biorxiv.org/content/10.1...
LSD1 serine 166 is a phosphorylation switch for chromatin landscaping, gene activation, and tissue remodeling
LSD1 is a histone 3 (H3) demethylase that can either repress or activate gene expression. We discover here that the so far enigmatic balance between these two activities in non-hormonal cancer cells i...
www.biorxiv.org
May 19, 2025 at 6:04 PM
Delighted that my lab could contribute to this beautiful story by Jukka Westermarck's lab www.biorxiv.org/content/10.1...
Reposted by Mukund Sharma
New preprint from us.
The study led by Mukund Sharma demonstrates how #PP2A mediated dephosphorylation of serine 166 of LSD1 functions as a phosphorylation switch between gene repression and activation by LSD1 and how this shapes tumor microenvironment.
www.biorxiv.org/content/10.1...
The study led by Mukund Sharma demonstrates how #PP2A mediated dephosphorylation of serine 166 of LSD1 functions as a phosphorylation switch between gene repression and activation by LSD1 and how this shapes tumor microenvironment.
www.biorxiv.org/content/10.1...
May 18, 2025 at 2:57 PM
New preprint from us.
The study led by Mukund Sharma demonstrates how #PP2A mediated dephosphorylation of serine 166 of LSD1 functions as a phosphorylation switch between gene repression and activation by LSD1 and how this shapes tumor microenvironment.
www.biorxiv.org/content/10.1...
The study led by Mukund Sharma demonstrates how #PP2A mediated dephosphorylation of serine 166 of LSD1 functions as a phosphorylation switch between gene repression and activation by LSD1 and how this shapes tumor microenvironment.
www.biorxiv.org/content/10.1...