MJ
@msjalali.bsky.social
Associate Prof @HarvardMed, MGH; Senior Lecturer @MITSloan. Systems scientist, developing simulation models for population-based health problems
Pinned
MJ
@msjalali.bsky.social
· Aug 21
What happens when research funding gets cut (not just a little, but a lot)? Try our simulator to find out.
Our model BRIDGE quantifies the impact of NIH budget cuts in the US, built on 47 datasets (1995-2024) and projecting effects over 25 years.
mj-lab.mgh.harvard.edu/nih-budget-s...
Our model BRIDGE quantifies the impact of NIH budget cuts in the US, built on 47 datasets (1995-2024) and projecting effects over 25 years.
mj-lab.mgh.harvard.edu/nih-budget-s...
New perspective: Hospitals face cyber threats shaped by human decisions under pressure, but collecting behavioral data is often limited. Synthetic behavioral data + simulation may offer a way to explore these patterns, though it needs careful evaluation: journals.plos.org/digitalhealt... @plos.org
journals.plos.org
November 9, 2025 at 4:07 PM
New perspective: Hospitals face cyber threats shaped by human decisions under pressure, but collecting behavioral data is often limited. Synthetic behavioral data + simulation may offer a way to explore these patterns, though it needs careful evaluation: journals.plos.org/digitalhealt... @plos.org
Delighted to welcome Dr. Songul Cinaroglu, Associate Professor of Health Care Management at Hacettepe University in Turkey, to our lab this year as a Fulbright Visiting Scholar.
September 15, 2025 at 7:46 PM
Delighted to welcome Dr. Songul Cinaroglu, Associate Professor of Health Care Management at Hacettepe University in Turkey, to our lab this year as a Fulbright Visiting Scholar.
The sad irony: funders want to include community members with no grant-writing background, but their applications are so demanding that even seasoned applicants struggle
August 23, 2025 at 5:14 PM
The sad irony: funders want to include community members with no grant-writing background, but their applications are so demanding that even seasoned applicants struggle
What happens when research funding gets cut (not just a little, but a lot)? Try our simulator to find out.
Our model BRIDGE quantifies the impact of NIH budget cuts in the US, built on 47 datasets (1995-2024) and projecting effects over 25 years.
mj-lab.mgh.harvard.edu/nih-budget-s...
Our model BRIDGE quantifies the impact of NIH budget cuts in the US, built on 47 datasets (1995-2024) and projecting effects over 25 years.
mj-lab.mgh.harvard.edu/nih-budget-s...
August 21, 2025 at 11:42 AM
What happens when research funding gets cut (not just a little, but a lot)? Try our simulator to find out.
Our model BRIDGE quantifies the impact of NIH budget cuts in the US, built on 47 datasets (1995-2024) and projecting effects over 25 years.
mj-lab.mgh.harvard.edu/nih-budget-s...
Our model BRIDGE quantifies the impact of NIH budget cuts in the US, built on 47 datasets (1995-2024) and projecting effects over 25 years.
mj-lab.mgh.harvard.edu/nih-budget-s...
Reposted by MJ
Four kinds of harmful long-term consequences from #Trump cuts to #nih:
https://jamanetwork.com/journals/jama-health-forum/fullarticle/2836433
"First, a reduction in fundamental research, which contributes to discoveries, could slow future innovations. Second, the erosion of human capital due to […]
https://jamanetwork.com/journals/jama-health-forum/fullarticle/2836433
"First, a reduction in fundamental research, which contributes to discoveries, could slow future innovations. Second, the erosion of human capital due to […]
Original post on fediscience.org
fediscience.org
July 29, 2025 at 1:35 PM
Four kinds of harmful long-term consequences from #Trump cuts to #nih:
https://jamanetwork.com/journals/jama-health-forum/fullarticle/2836433
"First, a reduction in fundamental research, which contributes to discoveries, could slow future innovations. Second, the erosion of human capital due to […]
https://jamanetwork.com/journals/jama-health-forum/fullarticle/2836433
"First, a reduction in fundamental research, which contributes to discoveries, could slow future innovations. Second, the erosion of human capital due to […]
Reposted by MJ
“…health care expenditures could increase as greater reliance on private sector research and development increases the costs of medical innovations. Finally, decreased investment in public health and translational research may lead to missed opportunities for disease prevention”
Potential Trade-Offs of Proposed Cuts to the US National Institutes of Health
This qualitative systems modeling analysis examines potential long-term impacts of National Institutes of Health funding constraints in biomedical innovation and health care costs.
jamanetwork.com
July 29, 2025 at 12:04 AM
“…health care expenditures could increase as greater reliance on private sector research and development increases the costs of medical innovations. Finally, decreased investment in public health and translational research may lead to missed opportunities for disease prevention”
Reposted by MJ
"Cutting NIH funding weakens foundational research, limiting the scientific groundwork and workforce needed for future biomedical research and reducing the pipeline of discoveries that fuel private sector innovation." jamanetwork.com/journals/jam...
Potential Trade-Offs of Proposed Cuts to the US National Institutes of Health
This qualitative systems modeling analysis examines potential long-term impacts of National Institutes of Health funding constraints in biomedical innovation and health care costs.
jamanetwork.com
July 28, 2025 at 3:35 PM
"Cutting NIH funding weakens foundational research, limiting the scientific groundwork and workforce needed for future biomedical research and reducing the pipeline of discoveries that fuel private sector innovation." jamanetwork.com/journals/jam...
Reposted by MJ
"Public investment in biomedical research is not merely a budgetary decision; it is an investment in human health, longevity, and quality of life." jamanetwork.com/journals/jam...
Potential Trade-Offs of Proposed Cuts to the US National Institutes of Health
This qualitative systems modeling analysis examines potential long-term impacts of National Institutes of Health funding constraints in biomedical innovation and health care costs.
jamanetwork.com
July 28, 2025 at 3:35 PM
"Public investment in biomedical research is not merely a budgetary decision; it is an investment in human health, longevity, and quality of life." jamanetwork.com/journals/jam...
Reposted by MJ
Over the long haul, cuts to Nat'l Institutes of Health budget could cost more than is actually saved. As a key sponsor of foundational research & scientific workforce training, the NIH plays a vital role in biomedical innovation jamanetwork.com/journals/jam...
Potential Trade-Offs of Proposed Cuts to the US National Institutes of Health
This qualitative systems modeling analysis examines potential long-term impacts of National Institutes of Health funding constraints in biomedical innovation and health care costs.
jamanetwork.com
July 28, 2025 at 5:21 PM
Over the long haul, cuts to Nat'l Institutes of Health budget could cost more than is actually saved. As a key sponsor of foundational research & scientific workforce training, the NIH plays a vital role in biomedical innovation jamanetwork.com/journals/jam...
Reposted by MJ
"Results of this qualitative analysis using systems modeling suggest that NIH budget reductions may have far-reaching implications for scientific progress, the biomedical innovation environment, and health care costs." jamanetwork.com/journals/jam... #research #funding #science @jama.com
Potential Trade-Offs of Proposed Cuts to the US National Institutes of Health
This qualitative systems modeling analysis examines potential long-term impacts of National Institutes of Health funding constraints in biomedical innovation and health care costs.
jamanetwork.com
July 28, 2025 at 2:09 PM
"Results of this qualitative analysis using systems modeling suggest that NIH budget reductions may have far-reaching implications for scientific progress, the biomedical innovation environment, and health care costs." jamanetwork.com/journals/jam... #research #funding #science @jama.com
Reposted by MJ
Potential Trade-Offs of Proposed Cuts to the US National Institutes of Health jamanetwork.com/journals/jam... (open access) @jama.com
Potential Trade-Offs of Proposed Cuts to the US National Institutes of Health
This qualitative systems modeling analysis examines potential long-term impacts of National Institutes of Health funding constraints in biomedical innovation and health care costs.
jamanetwork.com
July 28, 2025 at 12:43 PM
Potential Trade-Offs of Proposed Cuts to the US National Institutes of Health jamanetwork.com/journals/jam... (open access) @jama.com
Reposted by MJ
Special Communication: Proposed NIH budget cuts may result in reduced scientific progress, diminished biomedical workforce development, increased health care costs, and slowed innovation.
ja.ma/3UuQmad
ja.ma/3UuQmad
July 25, 2025 at 3:20 PM
Special Communication: Proposed NIH budget cuts may result in reduced scientific progress, diminished biomedical workforce development, increased health care costs, and slowed innovation.
ja.ma/3UuQmad
ja.ma/3UuQmad
Fewer discoveries. Fewer scientists. Higher health costs.
New in JAMA Health Forum: Proposed NIH cuts aren’t just a budget move; they could reshape how science happens in the US.
We mapped the ripple effects:
jamanetwork.com/journals/jam...
@jamahealthforum.bsky.social
New in JAMA Health Forum: Proposed NIH cuts aren’t just a budget move; they could reshape how science happens in the US.
We mapped the ripple effects:
jamanetwork.com/journals/jam...
@jamahealthforum.bsky.social
Potential Trade-Offs of Proposed Cuts to the US National Institutes of Health
This qualitative systems modeling analysis examines potential long-term impacts of National Institutes of Health funding constraints in biomedical innovation and health care costs.
jamanetwork.com
July 25, 2025 at 4:13 PM
Fewer discoveries. Fewer scientists. Higher health costs.
New in JAMA Health Forum: Proposed NIH cuts aren’t just a budget move; they could reshape how science happens in the US.
We mapped the ripple effects:
jamanetwork.com/journals/jam...
@jamahealthforum.bsky.social
New in JAMA Health Forum: Proposed NIH cuts aren’t just a budget move; they could reshape how science happens in the US.
We mapped the ripple effects:
jamanetwork.com/journals/jam...
@jamahealthforum.bsky.social
New paper: Overdose death spikes aren’t all the same; local patterns matter. In MA, some are driven by cocaine, others by stimulants or fentanyl. What’s behind a spike shifts by county, underscoring the need for local response strategies
bmjpublichealth.bmj.com/content/3/2/...
bmjpublichealth.bmj.com/content/3/2/...
Drug involvement variations in overdose death spikes: county-level analysis in Massachusetts
Background Communities often experience relatively quiet periods disrupted by sudden surges of drug overdoses, suggesting that the risk of death can change substantially in a short period. Multiple su...
bmjpublichealth.bmj.com
July 15, 2025 at 11:56 AM
New paper: Overdose death spikes aren’t all the same; local patterns matter. In MA, some are driven by cocaine, others by stimulants or fentanyl. What’s behind a spike shifts by county, underscoring the need for local response strategies
bmjpublichealth.bmj.com/content/3/2/...
bmjpublichealth.bmj.com/content/3/2/...
I'll be teaching system dynamics for two days in Bahir Dar, Ethiopia, May 31-June 1, thanks to the Amhara Public Health Institute for organizing and to @who.int for their partnership. Looking forward to working with researchers and government colleagues and building new partnerships in the region!
May 24, 2025 at 1:09 PM
I'll be teaching system dynamics for two days in Bahir Dar, Ethiopia, May 31-June 1, thanks to the Amhara Public Health Institute for organizing and to @who.int for their partnership. Looking forward to working with researchers and government colleagues and building new partnerships in the region!
Reposted by MJ
A new #LetterToScience argues that the U.S. budget cuts to WHO and USAID investments "will have both immediate and long-term consequences." scim.ag/4kcWEqw
May 21, 2025 at 1:40 PM
A new #LetterToScience argues that the U.S. budget cuts to WHO and USAID investments "will have both immediate and long-term consequences." scim.ag/4kcWEqw
In my letter in Science, I argue that pulling back U.S. support for WHO and USAID creates ripple effects far beyond the immediate cuts. Weakening them doesn’t just strain other countries, it circles back to affect Americans.
www.science.org/doi/pdf/10.1...
www.science.org/doi/pdf/10.1...
WHO and USAID budget cuts hurt the US
www.science.org
May 9, 2025 at 12:49 AM
In my letter in Science, I argue that pulling back U.S. support for WHO and USAID creates ripple effects far beyond the immediate cuts. Weakening them doesn’t just strain other countries, it circles back to affect Americans.
www.science.org/doi/pdf/10.1...
www.science.org/doi/pdf/10.1...
Public health took a hard hit recently, and more might be on the way. Major shake-ups at the FDA, CDC, NIH, and other agencies, along with funding cuts and job losses, have put serious pressure on research institutions. This isn’t just disruption; it’s a big system shock.
April 10, 2025 at 2:02 PM
Public health took a hard hit recently, and more might be on the way. Major shake-ups at the FDA, CDC, NIH, and other agencies, along with funding cuts and job losses, have put serious pressure on research institutions. This isn’t just disruption; it’s a big system shock.
Over the years, I’ve worked on models to understand complex problems. The topics change (and the acronyms get longer!) but some patterns just won’t quit. Here are two things I’ve learned:
April 10, 2025 at 11:43 AM
Over the years, I’ve worked on models to understand complex problems. The topics change (and the acronyms get longer!) but some patterns just won’t quit. Here are two things I’ve learned:
Reposted by MJ
The association between buprenorphine doses above 16 milligrams and treatment retention in a multi-payer national sample in the United States, 2014 to 2021. Full study by Erin Stringfellow and colleagues @harvardmed.bsky.social buff.ly/oAGtrcp
March 4, 2025 at 11:21 AM
The association between buprenorphine doses above 16 milligrams and treatment retention in a multi-payer national sample in the United States, 2014 to 2021. Full study by Erin Stringfellow and colleagues @harvardmed.bsky.social buff.ly/oAGtrcp
Off to Ireland for our annual European Commission grant meeting. Looking forward to catching up with colleagues and friends in Dublin and Maynooth this week!
March 30, 2025 at 6:10 PM
Off to Ireland for our annual European Commission grant meeting. Looking forward to catching up with colleagues and friends in Dublin and Maynooth this week!
Causal graphs are widely used but different sources—experts or AI—produce variations for the same problem. How to compare them? Our new study discusses metrics for evaluating semantic & structural similarities, testing them on 2K AI-generated graphs
https://papers.ssrn.com/sol3/papers.cfm?ab...
https://papers.ssrn.com/sol3/papers.cfm?ab...
March 30, 2025 at 6:10 PM
Causal graphs are widely used but different sources—experts or AI—produce variations for the same problem. How to compare them? Our new study discusses metrics for evaluating semantic & structural similarities, testing them on 2K AI-generated graphs
https://papers.ssrn.com/sol3/papers.cfm?ab...
https://papers.ssrn.com/sol3/papers.cfm?ab...
📢 Slashing NIH Funding: Trump’s Gamble on Science & Health
Our draft on how NIH cuts could disrupt research, industry, healthcare—impacting jobs, innovation, economy!
Using a systems approach, we uncover overlooked tradeoffs.
Share thoughts as we revise: https://mj-lab.mgh.harvard.edu/wp-cont...
Our draft on how NIH cuts could disrupt research, industry, healthcare—impacting jobs, innovation, economy!
Using a systems approach, we uncover overlooked tradeoffs.
Share thoughts as we revise: https://mj-lab.mgh.harvard.edu/wp-cont...
March 30, 2025 at 6:10 PM
📢 Slashing NIH Funding: Trump’s Gamble on Science & Health
Our draft on how NIH cuts could disrupt research, industry, healthcare—impacting jobs, innovation, economy!
Using a systems approach, we uncover overlooked tradeoffs.
Share thoughts as we revise: https://mj-lab.mgh.harvard.edu/wp-cont...
Our draft on how NIH cuts could disrupt research, industry, healthcare—impacting jobs, innovation, economy!
Using a systems approach, we uncover overlooked tradeoffs.
Share thoughts as we revise: https://mj-lab.mgh.harvard.edu/wp-cont...