Max Ruwolt
@mruwolt.bsky.social
Staff Scientist in Mass spectrometry platform @fmp-berlin.de. Interested in cross-linking mass spectrometry and interactomics.
Big congrats to my colleagues upstairs! Great work now published in @natchem.nature.com. Always happy to run #proteomics experiments with you. 🤝
🔥After years of hard work, it's finally out in @natchem.nature.com🔥 The Hackenberger group @fmp-berlin.de developed #🎯DarT-labeling, a #photocatalyticproximitylabeling method using deazaflavin - a ✅ biocompatible ✅ easily synthesized ✅ chemically benign #photocatalyst
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Energy-transfer photoproximity labelling in live cells using an organic cofactor - Nature Chemistry
Current photoproximity labelling methods often require metal-based catalysts to map protein interactomes but, owing to their toxicity, they have limited intracellular applicability. A deazaflavin cofa...
www.nature.com
September 17, 2025 at 1:40 PM
Big congrats to my colleagues upstairs! Great work now published in @natchem.nature.com. Always happy to run #proteomics experiments with you. 🤝
Reposted by Max Ruwolt
AIRPred: A Deep Learning Model Predictor for Peptide Intensity Ratios in Cross-Linking Mass Spectrometry Improves Cross-Link Spectrum Matching pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
August 27, 2025 at 6:00 PM
AIRPred: A Deep Learning Model Predictor for Peptide Intensity Ratios in Cross-Linking Mass Spectrometry Improves Cross-Link Spectrum Matching pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
Brace yourselves! Arif from the Fiedler lab discovered+characterized in collaboration with us & other groups within the @fmp-berlin.de a novel PTM: autocatalytic oligophosphorylation (up to 6 Phosphates 😲). Still mysterious in origin, function & regulation.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation - Nature Chemistry
Our understanding of how post-translational modification—protein phosphorylation—impacts the complexity of eukaryotic signalling pathways is continuously expanding. Now, protein oligophosphorylation h...
www.nature.com
August 20, 2025 at 9:58 PM
Brace yourselves! Arif from the Fiedler lab discovered+characterized in collaboration with us & other groups within the @fmp-berlin.de a novel PTM: autocatalytic oligophosphorylation (up to 6 Phosphates 😲). Still mysterious in origin, function & regulation.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A fun little side project from our FMP MS platform just got published! Previously, we struggled with messy Excel sheets to monitor machine performance and allocate machine time to users. Now, Q2C combines those management tasks into one user-friendly, GUI-based software. 💻
Q2C: A software for managing mass spectrometry facilities www.sciencedirect.co...
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#proteomics #prot-paper
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#proteomics #prot-paper
August 5, 2025 at 4:34 PM
A fun little side project from our FMP MS platform just got published! Previously, we struggled with messy Excel sheets to monitor machine performance and allocate machine time to users. Now, Q2C combines those management tasks into one user-friendly, GUI-based software. 💻
Reposted by Max Ruwolt
Check out Structural Host–Virus Interactome Profiling (SHVIP) in intact cells infected with Herpes Simplex Virus type 1 (HSV-1)! Now published!
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec
Structural host-virus interactome profiling of intact infected cells - Nature Communications
Virus-host protein-protein interactions are fundamental to viral pathogenesis, yet few are structurally resolved. Here, the authors combine cross-linking mass spectrometry, bio-orthogonal labeling and...
www.nature.com
July 22, 2025 at 8:15 AM
Check out Structural Host–Virus Interactome Profiling (SHVIP) in intact cells infected with Herpes Simplex Virus type 1 (HSV-1)! Now published!
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec