Groussin & Poyet Labs
@mmmicrobiomelab.bsky.social
The Groussin & Poyet Labs at Kiel University, Germany
Host-microbiome systems in health & disease
https://mmmicrobiomelab.org/
https://microbiomeconservancy.org/
Host-microbiome systems in health & disease
https://mmmicrobiomelab.org/
https://microbiomeconservancy.org/
Reposted by Groussin & Poyet Labs
How does industrialization and lifestyle impact our interactions with gut microbiomes? And what is the consequence of these perturbations on our physiology?
Discover findings from our new study addressing these questions:
www.biorxiv.org/content/10.1...
#microbiome #globalhealth #GMbC
Discover findings from our new study addressing these questions:
www.biorxiv.org/content/10.1...
#microbiome #globalhealth #GMbC
www.biorxiv.org
November 12, 2025 at 3:45 PM
How does industrialization and lifestyle impact our interactions with gut microbiomes? And what is the consequence of these perturbations on our physiology?
Discover findings from our new study addressing these questions:
www.biorxiv.org/content/10.1...
#microbiome #globalhealth #GMbC
Discover findings from our new study addressing these questions:
www.biorxiv.org/content/10.1...
#microbiome #globalhealth #GMbC
Reposted by Groussin & Poyet Labs
Do gut bacteria evolve differently in industrialized vs. non-industrialized humans?
Our new study reveals that industrialization drives parallel genomic adaptations across gut bacterial species worldwide:
www.biorxiv.org/content/10.1...
#microbiome #globalhealth #GMbC #genome #evolution
Our new study reveals that industrialization drives parallel genomic adaptations across gut bacterial species worldwide:
www.biorxiv.org/content/10.1...
#microbiome #globalhealth #GMbC #genome #evolution
Convergent genomic responses of human gut bacteria to variations in industrialization
To what extent gut bacteria respond to the distinct ecological pressures imposed by human lifestyle remains unclear. Here, we investigate how genomic adaptation in gut bacteria differ between industri...
www.biorxiv.org
November 12, 2025 at 3:49 PM
Do gut bacteria evolve differently in industrialized vs. non-industrialized humans?
Our new study reveals that industrialization drives parallel genomic adaptations across gut bacterial species worldwide:
www.biorxiv.org/content/10.1...
#microbiome #globalhealth #GMbC #genome #evolution
Our new study reveals that industrialization drives parallel genomic adaptations across gut bacterial species worldwide:
www.biorxiv.org/content/10.1...
#microbiome #globalhealth #GMbC #genome #evolution
Alexandra Deutsch, Zaira Zafroon, Hina Ayub, Emmanuel Quaye, Ana Schaan, Andre Geisler, and Johanna Saalfrank from @mmmicrobiomelab.bsky.social are in Milan for the @femsmicro.org conference 🇮🇹 🎉
Meet them all at #FEMS2025!
Meet them all at #FEMS2025!
July 14, 2025 at 7:31 AM
Alexandra Deutsch, Zaira Zafroon, Hina Ayub, Emmanuel Quaye, Ana Schaan, Andre Geisler, and Johanna Saalfrank from @mmmicrobiomelab.bsky.social are in Milan for the @femsmicro.org conference 🇮🇹 🎉
Meet them all at #FEMS2025!
Meet them all at #FEMS2025!
🎓 Huge congratulations to Dr. Aya Madhy for successfully defending her PhD! A major milestone achieved, we couldn’t be prouder! 🥹🎉
Check out some of her work: www.sciencedirect.com/science/arti...
academic.oup.com/ecco-jcc/art...
www.biorxiv.org/content/10.1...
@uni-kiel.de
#PhDDefense #PhD
Check out some of her work: www.sciencedirect.com/science/arti...
academic.oup.com/ecco-jcc/art...
www.biorxiv.org/content/10.1...
@uni-kiel.de
#PhDDefense #PhD
July 11, 2025 at 11:16 AM
🎓 Huge congratulations to Dr. Aya Madhy for successfully defending her PhD! A major milestone achieved, we couldn’t be prouder! 🥹🎉
Check out some of her work: www.sciencedirect.com/science/arti...
academic.oup.com/ecco-jcc/art...
www.biorxiv.org/content/10.1...
@uni-kiel.de
#PhDDefense #PhD
Check out some of her work: www.sciencedirect.com/science/arti...
academic.oup.com/ecco-jcc/art...
www.biorxiv.org/content/10.1...
@uni-kiel.de
#PhDDefense #PhD
Reposted by Groussin & Poyet Labs
🎉 Congratulations to Djenet Bousbaine, winner of the 2025 NOSTER & Science Microbiome Prize for her work to illuminate how the immune system responds to the beneficial skin microbiome.
Learn more: scim.ag/4lVwpFx
Learn more: scim.ag/4lVwpFx
July 4, 2025 at 2:07 PM
🎉 Congratulations to Djenet Bousbaine, winner of the 2025 NOSTER & Science Microbiome Prize for her work to illuminate how the immune system responds to the beneficial skin microbiome.
Learn more: scim.ag/4lVwpFx
Learn more: scim.ag/4lVwpFx
Reposted by Groussin & Poyet Labs
The #CRC1182 was represented again at the 2025 #KielerWoche together with KLS and PMI Cluster of Excellence. Here are a few images from the #KielerUniLive @uni-kiel.de event featuring our Digital Meta Poster, Sponge Pop-Up Cards and more:
www.metaorganism-research.com/news/crc-118...
www.metaorganism-research.com/news/crc-118...
June 26, 2025 at 10:53 AM
The #CRC1182 was represented again at the 2025 #KielerWoche together with KLS and PMI Cluster of Excellence. Here are a few images from the #KielerUniLive @uni-kiel.de event featuring our Digital Meta Poster, Sponge Pop-Up Cards and more:
www.metaorganism-research.com/news/crc-118...
www.metaorganism-research.com/news/crc-118...
Reposted by Groussin & Poyet Labs
New publication from the Global Microbiome Conservancy @mmmicrobiomelab.bsky.social!
Leveraging our dataset from Peninsular Malaysia, we report a clear stratification of microbial community structure, diversity and composition, along the rural–urban gradient.
www.nature.com/articles/s41...
Leveraging our dataset from Peninsular Malaysia, we report a clear stratification of microbial community structure, diversity and composition, along the rural–urban gradient.
www.nature.com/articles/s41...
Gut microbiota profiles of peninsular Malaysian populations are associated with urbanization and lifestyle - Scientific Reports
Scientific Reports - Gut microbiota profiles of peninsular Malaysian populations are associated with urbanization and lifestyle
www.nature.com
July 8, 2025 at 10:16 AM
New publication from the Global Microbiome Conservancy @mmmicrobiomelab.bsky.social!
Leveraging our dataset from Peninsular Malaysia, we report a clear stratification of microbial community structure, diversity and composition, along the rural–urban gradient.
www.nature.com/articles/s41...
Leveraging our dataset from Peninsular Malaysia, we report a clear stratification of microbial community structure, diversity and composition, along the rural–urban gradient.
www.nature.com/articles/s41...
Reposted by Groussin & Poyet Labs
This paper has been a long time coming: We looked at the genomes of historical bacterial samples over a century to look for trends of antibiotic resistance genes, finding multiple instances of them in infections before the age of antibiotics, but an increase in both frequency and mobility after
Genomic resistance in historical clinical isolates increased in frequency and mobility after the age of antibiotics https://www.biorxiv.org/content/10.1101/2025.01.16.633422v1
January 17, 2025 at 8:53 PM
This paper has been a long time coming: We looked at the genomes of historical bacterial samples over a century to look for trends of antibiotic resistance genes, finding multiple instances of them in infections before the age of antibiotics, but an increase in both frequency and mobility after
Reposted by Groussin & Poyet Labs
Check out this amazing preprint from my @isbscience.org colleague @annabiosys.bsky.social's lab!
Gupta et al. captured the entire infection cycle of an uncharacterized phage through single-cell RNA-seq of a B. fragilis population (capturing cells at different points in the infection cycle). 🤩
Gupta et al. captured the entire infection cycle of an uncharacterized phage through single-cell RNA-seq of a B. fragilis population (capturing cells at different points in the infection cycle). 🤩
How can single-cell transcriptomics profile phage infection in individual microbial cells? Check out our preprint with Anika Gupta, Norma Morella, Dmitry Sutormin & other authors, in collaboration with Georg Seelig (UW) and Neel Dey (Fred Hutch). www.biorxiv.org/content/10.1...
Combinatorial phenotypic landscape enables bacterial resistance to phage infection
Success of phage therapies is limited by bacterial defenses against phages. While a large variety of anti-phage defense mechanisms has been characterized, how expression of these systems is distribute...
www.biorxiv.org
January 17, 2025 at 11:11 PM
Check out this amazing preprint from my @isbscience.org colleague @annabiosys.bsky.social's lab!
Gupta et al. captured the entire infection cycle of an uncharacterized phage through single-cell RNA-seq of a B. fragilis population (capturing cells at different points in the infection cycle). 🤩
Gupta et al. captured the entire infection cycle of an uncharacterized phage through single-cell RNA-seq of a B. fragilis population (capturing cells at different points in the infection cycle). 🤩
Doing #Science is only half the work – you also need to share it with the world !🌍
Congratulations to our talented young scientists for great presentations of their research and winning well-deserved prizes at the First Research Festival of the Medical Faculty at
@uni-kiel.de !🧪
Congratulations to our talented young scientists for great presentations of their research and winning well-deserved prizes at the First Research Festival of the Medical Faculty at
@uni-kiel.de !🧪
December 16, 2024 at 12:41 PM
Doing #Science is only half the work – you also need to share it with the world !🌍
Congratulations to our talented young scientists for great presentations of their research and winning well-deserved prizes at the First Research Festival of the Medical Faculty at
@uni-kiel.de !🧪
Congratulations to our talented young scientists for great presentations of their research and winning well-deserved prizes at the First Research Festival of the Medical Faculty at
@uni-kiel.de !🧪
Reposted by Groussin & Poyet Labs
#BehindTheScience in our lab:
Chemostat bioreactors enable us to explore how targeted interventions influence gut microbiome communities of diverse compositions — insights that could shape the future of gut-related therapies 🧪💩
#MicrobiomeResearch #GutHealth
Chemostat bioreactors enable us to explore how targeted interventions influence gut microbiome communities of diverse compositions — insights that could shape the future of gut-related therapies 🧪💩
#MicrobiomeResearch #GutHealth
December 9, 2024 at 8:14 AM
#BehindTheScience in our lab:
Chemostat bioreactors enable us to explore how targeted interventions influence gut microbiome communities of diverse compositions — insights that could shape the future of gut-related therapies 🧪💩
#MicrobiomeResearch #GutHealth
Chemostat bioreactors enable us to explore how targeted interventions influence gut microbiome communities of diverse compositions — insights that could shape the future of gut-related therapies 🧪💩
#MicrobiomeResearch #GutHealth
Reposted by Groussin & Poyet Labs
If you missed my recent #MVIF talk on our precision nutrition work, you can catch it here youtu.be/L1VutD02lu8?...
Thanks to the organizers for providing these virtual events for free to the microbiome community! 🎉
@microbiomevif.bsky.social
Thanks to the organizers for providing these virtual events for free to the microbiome community! 🎉
@microbiomevif.bsky.social
Sean Gibbons - My Digital Gut: a tool set for microbiome-mediated precision nutrition | S04 MVIF34
YouTube video by Microbiome Virtual International Forum
youtu.be
December 9, 2024 at 5:36 PM
If you missed my recent #MVIF talk on our precision nutrition work, you can catch it here youtu.be/L1VutD02lu8?...
Thanks to the organizers for providing these virtual events for free to the microbiome community! 🎉
@microbiomevif.bsky.social
Thanks to the organizers for providing these virtual events for free to the microbiome community! 🎉
@microbiomevif.bsky.social
#BehindTheScience in our lab:
Chemostat bioreactors enable us to explore how targeted interventions influence gut microbiome communities of diverse compositions — insights that could shape the future of gut-related therapies 🧪💩
#MicrobiomeResearch #GutHealth
Chemostat bioreactors enable us to explore how targeted interventions influence gut microbiome communities of diverse compositions — insights that could shape the future of gut-related therapies 🧪💩
#MicrobiomeResearch #GutHealth
December 9, 2024 at 8:14 AM
#BehindTheScience in our lab:
Chemostat bioreactors enable us to explore how targeted interventions influence gut microbiome communities of diverse compositions — insights that could shape the future of gut-related therapies 🧪💩
#MicrobiomeResearch #GutHealth
Chemostat bioreactors enable us to explore how targeted interventions influence gut microbiome communities of diverse compositions — insights that could shape the future of gut-related therapies 🧪💩
#MicrobiomeResearch #GutHealth
Join our team at @UKSH_KI_HL and @kieluni!
We're hiring a Scientist/Postdoc to join our #Bioinformatics Platform and support cutting-edge biomedical & omics research!
Apply by Dec 24, 2024. Start Feb 1, 2025.
Please share!
jobs.uksh.de/job/Kiel-Sci...
We're hiring a Scientist/Postdoc to join our #Bioinformatics Platform and support cutting-edge biomedical & omics research!
Apply by Dec 24, 2024. Start Feb 1, 2025.
Please share!
jobs.uksh.de/job/Kiel-Sci...
December 9, 2024 at 8:13 AM
Join our team at @UKSH_KI_HL and @kieluni!
We're hiring a Scientist/Postdoc to join our #Bioinformatics Platform and support cutting-edge biomedical & omics research!
Apply by Dec 24, 2024. Start Feb 1, 2025.
Please share!
jobs.uksh.de/job/Kiel-Sci...
We're hiring a Scientist/Postdoc to join our #Bioinformatics Platform and support cutting-edge biomedical & omics research!
Apply by Dec 24, 2024. Start Feb 1, 2025.
Please share!
jobs.uksh.de/job/Kiel-Sci...
Reposted by Groussin & Poyet Labs
Excited to share Aya Mahdy's review about TCR-Seq (PhD candidate co-supervised by A. Franke), published in the Journal of Autoimmunity! 🎉
A must-read for #immunology enthusiasts! 🔬📖
www.sciencedirect.com/science/arti...
#TCRSeq #Autoimmunity #ScienceTwitter #PhDLife #Genomics #Bioinformatics
A must-read for #immunology enthusiasts! 🔬📖
www.sciencedirect.com/science/arti...
#TCRSeq #Autoimmunity #ScienceTwitter #PhDLife #Genomics #Bioinformatics
December 2, 2024 at 6:52 AM
Excited to share Aya Mahdy's review about TCR-Seq (PhD candidate co-supervised by A. Franke), published in the Journal of Autoimmunity! 🎉
A must-read for #immunology enthusiasts! 🔬📖
www.sciencedirect.com/science/arti...
#TCRSeq #Autoimmunity #ScienceTwitter #PhDLife #Genomics #Bioinformatics
A must-read for #immunology enthusiasts! 🔬📖
www.sciencedirect.com/science/arti...
#TCRSeq #Autoimmunity #ScienceTwitter #PhDLife #Genomics #Bioinformatics
Reposted by Groussin & Poyet Labs
Our Dr. h.c. Margaret McFall-Ngai talking about a revolution...
December 5, 2024 at 5:16 PM
Our Dr. h.c. Margaret McFall-Ngai talking about a revolution...
Reposted by Groussin & Poyet Labs
If you missed this year's ISB Virtual Microbiome Series, which focused on the gut-brain axis, you can catch the lectures and symposium talks here: gibbons.isbscience.org/news/2024/10...
@isbscience.org
@isbscience.org
A Gut Feeling: Microbes and Their Impacts on Our Minds
This year, ISB hosted a two-day virtual microbiome course and one-day symposium dedicated to exploring the gut-brain axis.
gibbons.isbscience.org
December 6, 2024 at 6:09 PM
If you missed this year's ISB Virtual Microbiome Series, which focused on the gut-brain axis, you can catch the lectures and symposium talks here: gibbons.isbscience.org/news/2024/10...
@isbscience.org
@isbscience.org
Reposted by Groussin & Poyet Labs
1/3 🌍 We're hiring! The Medical Systems Biology Lab at Kiel University is looking for a passionate #PostDoc in #Metabolic #Microbiome #Modeling. Join us at one of Europe’s microbiome research hubs and push the boundaries of microbiome science! @kieluni @UKSH_KI_HL
🔗 jobs.uksh.de/job/Kiel-Pos...
🔗 jobs.uksh.de/job/Kiel-Pos...
November 15, 2024 at 9:24 AM
1/3 🌍 We're hiring! The Medical Systems Biology Lab at Kiel University is looking for a passionate #PostDoc in #Metabolic #Microbiome #Modeling. Join us at one of Europe’s microbiome research hubs and push the boundaries of microbiome science! @kieluni @UKSH_KI_HL
🔗 jobs.uksh.de/job/Kiel-Pos...
🔗 jobs.uksh.de/job/Kiel-Pos...
Excited to share Aya Mahdy's review about TCR-Seq (PhD candidate co-supervised by A. Franke), published in the Journal of Autoimmunity! 🎉
A must-read for #immunology enthusiasts! 🔬📖
www.sciencedirect.com/science/arti...
#TCRSeq #Autoimmunity #ScienceTwitter #PhDLife #Genomics #Bioinformatics
A must-read for #immunology enthusiasts! 🔬📖
www.sciencedirect.com/science/arti...
#TCRSeq #Autoimmunity #ScienceTwitter #PhDLife #Genomics #Bioinformatics
December 2, 2024 at 6:52 AM
Excited to share Aya Mahdy's review about TCR-Seq (PhD candidate co-supervised by A. Franke), published in the Journal of Autoimmunity! 🎉
A must-read for #immunology enthusiasts! 🔬📖
www.sciencedirect.com/science/arti...
#TCRSeq #Autoimmunity #ScienceTwitter #PhDLife #Genomics #Bioinformatics
A must-read for #immunology enthusiasts! 🔬📖
www.sciencedirect.com/science/arti...
#TCRSeq #Autoimmunity #ScienceTwitter #PhDLife #Genomics #Bioinformatics
Reposted by Groussin & Poyet Labs
Gut microbiota strain richness is species specific and affects engraftment www.nature.com/articles/s41...
Gut microbiota strain richness is species specific and affects engraftment - Nature
Strain richness of gut microbiota ecosystems is a key characteristic underpinning engraftment in faecal microbiota transplantation, and could improve the design of defined live biotherapeuti...
www.nature.com
December 1, 2024 at 4:22 PM
Gut microbiota strain richness is species specific and affects engraftment www.nature.com/articles/s41...
Reposted by Groussin & Poyet Labs
Quite a comprehensive piece of work:
"Gut physiology and environment explain variations in human gut microbiome composition and metabolism."
www.nature.com/articles/s41...
Definitely worth checking out if you work on animal microbiomes, especially in the gut
"Gut physiology and environment explain variations in human gut microbiome composition and metabolism."
www.nature.com/articles/s41...
Definitely worth checking out if you work on animal microbiomes, especially in the gut
Gut physiology and environment explain variations in human gut microbiome composition and metabolism - Nature Microbiology
An observational longitudinal clinical trial, incorporating a SmartPill and metabolomics, reveals the role of host factors in shaping the gut microbiome in healthy human adults.
www.nature.com
November 30, 2024 at 7:28 PM
Quite a comprehensive piece of work:
"Gut physiology and environment explain variations in human gut microbiome composition and metabolism."
www.nature.com/articles/s41...
Definitely worth checking out if you work on animal microbiomes, especially in the gut
"Gut physiology and environment explain variations in human gut microbiome composition and metabolism."
www.nature.com/articles/s41...
Definitely worth checking out if you work on animal microbiomes, especially in the gut
Reposted by Groussin & Poyet Labs
How to write an excellent Review article @natrevbioeng.bsky.social #scisky #Science #REVIEW
Open Access
www.nature.com/articles/s44...
Open Access
www.nature.com/articles/s44...
November 23, 2024 at 6:09 PM
How to write an excellent Review article @natrevbioeng.bsky.social #scisky #Science #REVIEW
Open Access
www.nature.com/articles/s44...
Open Access
www.nature.com/articles/s44...
Reposted by Groussin & Poyet Labs
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
November 25, 2024 at 12:38 PM
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
🎉 Congrats Dr. Ana Schaan for winning the Kiel Life Science (KLS) Early Career Postdoc Award!
This prize will support in vitro & in vivo validation assays for her KiTE/MSCA project on investigating cholesterol metabolism by the gut #microbiome!
🏆👏
#kieluni #CAUKiel #MicroSky #Science
This prize will support in vitro & in vivo validation assays for her KiTE/MSCA project on investigating cholesterol metabolism by the gut #microbiome!
🏆👏
#kieluni #CAUKiel #MicroSky #Science
November 26, 2024 at 3:27 PM
🎉 Congrats Dr. Ana Schaan for winning the Kiel Life Science (KLS) Early Career Postdoc Award!
This prize will support in vitro & in vivo validation assays for her KiTE/MSCA project on investigating cholesterol metabolism by the gut #microbiome!
🏆👏
#kieluni #CAUKiel #MicroSky #Science
This prize will support in vitro & in vivo validation assays for her KiTE/MSCA project on investigating cholesterol metabolism by the gut #microbiome!
🏆👏
#kieluni #CAUKiel #MicroSky #Science
Reposted by Groussin & Poyet Labs
Returning after a first month of parental leave, I am thrilled to see many reasearchers moving to this place. A good timepoint to re-introduce myself:
I am a PostDoc at @mmmicrobiomelab.bsky.social interested in how the human microbiome is shaped by lifestyle, disease, genetics and evolution.
I am a PostDoc at @mmmicrobiomelab.bsky.social interested in how the human microbiome is shaped by lifestyle, disease, genetics and evolution.
November 22, 2024 at 8:55 AM
Returning after a first month of parental leave, I am thrilled to see many reasearchers moving to this place. A good timepoint to re-introduce myself:
I am a PostDoc at @mmmicrobiomelab.bsky.social interested in how the human microbiome is shaped by lifestyle, disease, genetics and evolution.
I am a PostDoc at @mmmicrobiomelab.bsky.social interested in how the human microbiome is shaped by lifestyle, disease, genetics and evolution.