@mleighton.bsky.social
Reposted
Johann du Buisson, Jannik Ehrich, mleighton.bsky.social, davidasivak.bsky.social, and John Bechhoefer introduce a one-coordinate test that infers heat flow to flag “demonic” operation. In kinesin simulations tuned to experiments, the motor grows more demon-like as active fluctuations rise.
September 27, 2025 at 3:00 PM
Johann du Buisson, Jannik Ehrich, mleighton.bsky.social, davidasivak.bsky.social, and John Bechhoefer introduce a one-coordinate test that infers heat flow to flag “demonic” operation. In kinesin simulations tuned to experiments, the motor grows more demon-like as active fluctuations rise.
Reposted
Our recent work (elifesciences.org/articles/104...) combines theory and experiments (by Alex Papagiannakis and Christine Jacobs-Wagner) to understand how chromosome segregation is coupled to growth in E coli. We demonstrate that the nonequilibrium dynamics of polysomes may play a key role.
July 7, 2025 at 2:03 PM
Our recent work (elifesciences.org/articles/104...) combines theory and experiments (by Alex Papagiannakis and Christine Jacobs-Wagner) to understand how chromosome segregation is coupled to growth in E coli. We demonstrate that the nonequilibrium dynamics of polysomes may play a key role.
New preprint out today: “Information Thermodynamics of Cellular Ion Pumps”. Led by talented undergraduate student Julián Jiménez-Paz, and working with @davidasivak.bsky.social, we explore the thermodynamics of cellular ion pumps like the sodium-potassium pump.
arxiv.org/abs/2506.11248
arxiv.org/abs/2506.11248
June 17, 2025 at 4:18 PM
New preprint out today: “Information Thermodynamics of Cellular Ion Pumps”. Led by talented undergraduate student Julián Jiménez-Paz, and working with @davidasivak.bsky.social, we explore the thermodynamics of cellular ion pumps like the sodium-potassium pump.
arxiv.org/abs/2506.11248
arxiv.org/abs/2506.11248
Reposted
Canada Excellence Research Chairs offer $4-8M over eight years to build a world-class research focus.
June 9, 2025 at 4:32 PM
Canada Excellence Research Chairs offer $4-8M over eight years to build a world-class research focus.
Interested in coarse-graining, irreversibility, or neural activity in the hippocampus?
If so, check out our new preprint exploring how maximizing the irreversibility preserved from microscopic dynamics leads to interpretable coarse-grained descriptions of biological systems!
If so, check out our new preprint exploring how maximizing the irreversibility preserved from microscopic dynamics leads to interpretable coarse-grained descriptions of biological systems!
Biology consumes energy at the microscale to power functions across all scales: From proteins and cells to entire populations of animals.
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
June 5, 2025 at 6:23 PM
Interested in coarse-graining, irreversibility, or neural activity in the hippocampus?
If so, check out our new preprint exploring how maximizing the irreversibility preserved from microscopic dynamics leads to interpretable coarse-grained descriptions of biological systems!
If so, check out our new preprint exploring how maximizing the irreversibility preserved from microscopic dynamics leads to interpretable coarse-grained descriptions of biological systems!
Reposted
Postdoc opportunity!
Join us in heavenly Vancouver (Canada) to develop fundamental nonequilibrium stat mech, thermo, and info theory applied to biomolecular machines and in close collaboration with experiment.
Details: www.sfu.ca/physics/siva...
Join us in heavenly Vancouver (Canada) to develop fundamental nonequilibrium stat mech, thermo, and info theory applied to biomolecular machines and in close collaboration with experiment.
Details: www.sfu.ca/physics/siva...
Postdoc Ad
www.sfu.ca
June 2, 2025 at 3:11 PM
Postdoc opportunity!
Join us in heavenly Vancouver (Canada) to develop fundamental nonequilibrium stat mech, thermo, and info theory applied to biomolecular machines and in close collaboration with experiment.
Details: www.sfu.ca/physics/siva...
Join us in heavenly Vancouver (Canada) to develop fundamental nonequilibrium stat mech, thermo, and info theory applied to biomolecular machines and in close collaboration with experiment.
Details: www.sfu.ca/physics/siva...
Now out in @annualreviews.bsky.social of Physical Chemistry: @davidasivak.bsky.social and I review recent work studying flows of free energy into, out of, and within molecular machines. These nanoscale protein machines convert energy within cells of all living organisms with remarkable efficiencies.
May 7, 2025 at 1:17 PM
Now out in @annualreviews.bsky.social of Physical Chemistry: @davidasivak.bsky.social and I review recent work studying flows of free energy into, out of, and within molecular machines. These nanoscale protein machines convert energy within cells of all living organisms with remarkable efficiencies.