Qiwei Yu
@qiweiyu.bsky.social
PhD candidate & Harold W. Dodds Fellow @Princeton | statistical mechanics & theoretical biophysics | previously @IBMResearch @Peking University @Rice University
https://qiweiyuu.github.io/
https://qiweiyuu.github.io/
Pinned
Qiwei Yu
@qiweiyu.bsky.social
· Jun 5
Biology consumes energy at the microscale to power functions across all scales: From proteins and cells to entire populations of animals.
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
Living systems operate nonequilibrium processes across many scales in space and time. Is there a model-free way to bridge the descriptions at different levels of coarse-graining? Here we find that preserving the evidence of time-reversal symmetry breaking works remarkably well!
As the march meeting abstract deadline approaches, please check out our session! Please RT/forward
For the 2026 APS March Meeting, please consider submitting your abstract to our new focus session on Cellular Sensing and Signaling (04.01.29), which aims to bridge theory and experiments to understand how cells sense and respond to environmental signals.
October 11, 2025 at 10:27 PM
As the march meeting abstract deadline approaches, please check out our session! Please RT/forward
For the 2026 APS March Meeting, please consider submitting your abstract to our new focus session on Cellular Sensing and Signaling (04.01.29), which aims to bridge theory and experiments to understand how cells sense and respond to environmental signals.
September 23, 2025 at 3:20 PM
For the 2026 APS March Meeting, please consider submitting your abstract to our new focus session on Cellular Sensing and Signaling (04.01.29), which aims to bridge theory and experiments to understand how cells sense and respond to environmental signals.
Reposted by Qiwei Yu
📸 Image of the month: August!
This month we are excited to feature “𝐏𝐚𝐭𝐭𝐞𝐫𝐧 𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐥𝐢𝐩𝐢𝐝 𝐝𝐨𝐦𝐚𝐢𝐧𝐬 𝐢𝐧 𝐛𝐢𝐥𝐚𝐲𝐞𝐫 𝐦𝐞𝐦𝐛𝐫𝐚𝐧𝐞𝐬” by Yu et al.
Learn more about their exciting research here: qiweiyuu.github.io
🔗 (paper): doi.org/10.1039/D5SM...
(1/4)
This month we are excited to feature “𝐏𝐚𝐭𝐭𝐞𝐫𝐧 𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐥𝐢𝐩𝐢𝐝 𝐝𝐨𝐦𝐚𝐢𝐧𝐬 𝐢𝐧 𝐛𝐢𝐥𝐚𝐲𝐞𝐫 𝐦𝐞𝐦𝐛𝐫𝐚𝐧𝐞𝐬” by Yu et al.
Learn more about their exciting research here: qiweiyuu.github.io
🔗 (paper): doi.org/10.1039/D5SM...
(1/4)
August 4, 2025 at 2:06 PM
📸 Image of the month: August!
This month we are excited to feature “𝐏𝐚𝐭𝐭𝐞𝐫𝐧 𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐥𝐢𝐩𝐢𝐝 𝐝𝐨𝐦𝐚𝐢𝐧𝐬 𝐢𝐧 𝐛𝐢𝐥𝐚𝐲𝐞𝐫 𝐦𝐞𝐦𝐛𝐫𝐚𝐧𝐞𝐬” by Yu et al.
Learn more about their exciting research here: qiweiyuu.github.io
🔗 (paper): doi.org/10.1039/D5SM...
(1/4)
This month we are excited to feature “𝐏𝐚𝐭𝐭𝐞𝐫𝐧 𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐥𝐢𝐩𝐢𝐝 𝐝𝐨𝐦𝐚𝐢𝐧𝐬 𝐢𝐧 𝐛𝐢𝐥𝐚𝐲𝐞𝐫 𝐦𝐞𝐦𝐛𝐫𝐚𝐧𝐞𝐬” by Yu et al.
Learn more about their exciting research here: qiweiyuu.github.io
🔗 (paper): doi.org/10.1039/D5SM...
(1/4)
Now out in Physical Review Letters: work led by Andrew Pyo showing that the accumulation of beneficial mutations can be greatly accelerated by a mutation rate that decreases with increasing relative fitness.
journals.aps.org/prl/abstract...
journals.aps.org/prl/abstract...
Evolutionary Benefits of Fitness-Dependent Mutation Rates
Motivated by recent observations that mutation rates can be correlated with individual fitness, we analyze an evolutionary hill-climbing model with fitness-dependent mutation rates. Our results show t...
journals.aps.org
July 27, 2025 at 11:21 PM
Now out in Physical Review Letters: work led by Andrew Pyo showing that the accumulation of beneficial mutations can be greatly accelerated by a mutation rate that decreases with increasing relative fitness.
journals.aps.org/prl/abstract...
journals.aps.org/prl/abstract...
Reposted by Qiwei Yu
Nature research paper: Mapping and engineering RNA-driven architecture of the multiphase nucleolus
https://go.nature.com/44Tib11
https://go.nature.com/44Tib11
Mapping and engineering RNA-driven architecture of the multiphase nucleolus - Nature
Spatially segregated rRNA processing dictates nucleolar morphology and drives outward progression of pre-ribosomal RNA through nucleolar phases.
go.nature.com
July 8, 2025 at 8:41 PM
Nature research paper: Mapping and engineering RNA-driven architecture of the multiphase nucleolus
https://go.nature.com/44Tib11
https://go.nature.com/44Tib11
Reposted by Qiwei Yu
Combining sequencing and imaging, @brangwynnelab.bsky.social maps the spatiotemporal dynamics of rRNA processing, demonstrating how rRNA serves as both a scaffold and a substrate for the nucleolus—a multiphase, liquid-like structure. 🧪 🧬
Mapping and engineering RNA-driven architecture of the multiphase nucleolus - Nature
Spatially segregated rRNA processing dictates nucleolar morphology and drives outward progression of pre-ribosomal RNA through nucleolar phases.
www.nature.com
July 14, 2025 at 2:06 PM
Combining sequencing and imaging, @brangwynnelab.bsky.social maps the spatiotemporal dynamics of rRNA processing, demonstrating how rRNA serves as both a scaffold and a substrate for the nucleolus—a multiphase, liquid-like structure. 🧪 🧬
Reposted by Qiwei Yu
Apply now to be a CPBF Fellow in 2026! puwebp.princeton.edu/AcadHire/app...
puwebp.princeton.edu
July 23, 2025 at 2:05 PM
Apply now to be a CPBF Fellow in 2026! puwebp.princeton.edu/AcadHire/app...
Our recent work (elifesciences.org/articles/104...) combines theory and experiments (by Alex Papagiannakis and Christine Jacobs-Wagner) to understand how chromosome segregation is coupled to growth in E coli. We demonstrate that the nonequilibrium dynamics of polysomes may play a key role.
July 7, 2025 at 2:03 PM
Our recent work (elifesciences.org/articles/104...) combines theory and experiments (by Alex Papagiannakis and Christine Jacobs-Wagner) to understand how chromosome segregation is coupled to growth in E coli. We demonstrate that the nonequilibrium dynamics of polysomes may play a key role.
Living systems operate nonequilibrium processes across many scales in space and time. Is there a model-free way to bridge the descriptions at different levels of coarse-graining? Here we find that preserving the evidence of time-reversal symmetry breaking works remarkably well!
Biology consumes energy at the microscale to power functions across all scales: From proteins and cells to entire populations of animals.
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
June 5, 2025 at 7:26 PM
Living systems operate nonequilibrium processes across many scales in space and time. Is there a model-free way to bridge the descriptions at different levels of coarse-graining? Here we find that preserving the evidence of time-reversal symmetry breaking works remarkably well!
Reposted by Qiwei Yu
Biology consumes energy at the microscale to power functions across all scales: From proteins and cells to entire populations of animals.
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
June 5, 2025 at 6:17 PM
Biology consumes energy at the microscale to power functions across all scales: From proteins and cells to entire populations of animals.
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
Led by @qiweiyu.bsky.social and @mleighton.bsky.social, we study how coarse-graining can help to bridge this gap 👇🧵
arxiv.org/abs/2506.01909
Reposted by Qiwei Yu
Postdoc opportunity!
Join us in heavenly Vancouver (Canada) to develop fundamental nonequilibrium stat mech, thermo, and info theory applied to biomolecular machines and in close collaboration with experiment.
Details: www.sfu.ca/physics/siva...
Join us in heavenly Vancouver (Canada) to develop fundamental nonequilibrium stat mech, thermo, and info theory applied to biomolecular machines and in close collaboration with experiment.
Details: www.sfu.ca/physics/siva...
Postdoc Ad
www.sfu.ca
June 2, 2025 at 3:11 PM
Postdoc opportunity!
Join us in heavenly Vancouver (Canada) to develop fundamental nonequilibrium stat mech, thermo, and info theory applied to biomolecular machines and in close collaboration with experiment.
Details: www.sfu.ca/physics/siva...
Join us in heavenly Vancouver (Canada) to develop fundamental nonequilibrium stat mech, thermo, and info theory applied to biomolecular machines and in close collaboration with experiment.
Details: www.sfu.ca/physics/siva...
Our work on lipid domain pattern formation is now published in Soft Matter as part of the themed collection "Pioneering Investigators": pubs.rsc.org/en/content/a...
Grateful for my advisor Andrej Košmrlj for his mentorship, and for our collaborators for teaching us a lot about membranes!
Grateful for my advisor Andrej Košmrlj for his mentorship, and for our collaborators for teaching us a lot about membranes!
May 9, 2025 at 12:32 AM
Our work on lipid domain pattern formation is now published in Soft Matter as part of the themed collection "Pioneering Investigators": pubs.rsc.org/en/content/a...
Grateful for my advisor Andrej Košmrlj for his mentorship, and for our collaborators for teaching us a lot about membranes!
Grateful for my advisor Andrej Košmrlj for his mentorship, and for our collaborators for teaching us a lot about membranes!
Excited to be at @apsphysics.bsky.social March meeting this week. Check out the following talks from my collaborators and me!
March 17, 2025 at 1:26 AM
Excited to be at @apsphysics.bsky.social March meeting this week. Check out the following talks from my collaborators and me!