Miriam Klein-Flügge 🧠
banner
mkflugge.bsky.social
Miriam Klein-Flügge 🧠
@mkflugge.bsky.social
Cognitive Neuroscientist | Associate Prof at Uni Oxford @oxexppsy | Mum
PI of Motivation, Decision & Neurostimulation Lab
Decision making | Ultrasound | Mental health
(she/her)

Group: modeslab.org
Personal: https://users.ox.ac.uk/~xpsy0747
Pinned
We are super excited about the first human transcranial ultrasound study from our lab which is now on BiorXiv, showing the amygdala‘s role in processing ambiguous emotions and showing TUS changed resting-state connectivity and metabolite concentrations (GABA) in the amygdala - a huge team effort! 🥳🙏🏼
Very happy to share my first preprint from @oxexppsy.bsky.social @oxneuro.bsky.social ! We (me + co-first authors @lilweb.bsky.social @mirunarascu.bsky.social + PI @mkflugge.bsky.social + many others) used transcranial focused ultrasound stimulation (TUS/tFUS/LIFU) of the human amygdala ... (1/15)
Had a brilliant day at the Mechanistic Basis of Foraging conference in Birmingham so far - presenting @johalgermissen.bsky.social’s work and listening to many great speakers 🥳🧠🐠
Nearly ready to go! Mechanistic Basis of Foraging 2025!
November 4, 2025 at 4:05 PM
Super important post for people in transcranial ultrasound neurostim - please read👇🏼
A brain injury was reported in a trial using ultrasound, framed as low-intensity TUS. Kim Butts Pauly and I reviewed the case and disagreed with how it's presented. Key acoustic data are missing.
Case: doi.org/10.1016/j.br...
Letters: www.elsa-fouragnan.com/blog | web.stanford.edu/~kimbutts/Le...
Brain Injury During Focused Ultrasound Neuromodulation for Substance Use Disorder
www.sciencedirect.com
November 3, 2025 at 6:24 PM
Reposted by Miriam Klein-Flügge 🧠
NEW: The Life and Mind Building is now open 🎉

Home to @biology.ox.ac.uk, @oxexppsy.bsky.social and @ineosoxford.bsky.social, the building will bring together 1,400+ researchers and students to tackle global challenges – from mental health to climate change.

[1/7]
October 15, 2025 at 9:40 AM
Very proud of @sankalpgarud.bsky.social for this heroic effort studying human affiliation decisions which is now out in @pnas.org 🥳 Check out the thread below for quick summary of what we found 👇
How do we decide to reach out and make friends?

My PhD work on this question is out today in @pnas.org 🎉

Study done in collaboration with the incredible
@mirunarascu.bsky.social, @sorcha-hamilton.bsky.social, Ingrid Yu, and my two amazing supervisors, Matthew Rushworth and @mkflugge.bsky.social👇
October 14, 2025 at 6:55 PM
Reposted by Miriam Klein-Flügge 🧠
🚨We believe this is a major step forward in how we study hippocampus function in healthy humans.

Using novel behavioral tasks, fMRI, RL & RNN modeling, and transcranial ultrasound stimulation (TUS), we demonstrate the causal role of hippocampus in relational structure learning.
August 28, 2025 at 2:00 PM
We are super excited about the first human transcranial ultrasound study from our lab which is now on BiorXiv, showing the amygdala‘s role in processing ambiguous emotions and showing TUS changed resting-state connectivity and metabolite concentrations (GABA) in the amygdala - a huge team effort! 🥳🙏🏼
Very happy to share my first preprint from @oxexppsy.bsky.social @oxneuro.bsky.social ! We (me + co-first authors @lilweb.bsky.social @mirunarascu.bsky.social + PI @mkflugge.bsky.social + many others) used transcranial focused ultrasound stimulation (TUS/tFUS/LIFU) of the human amygdala ... (1/15)
August 20, 2025 at 6:45 AM
Reposted by Miriam Klein-Flügge 🧠
📢 Job announcement: Two (!) 3-year postdoc jobs in our lab at UCL 📢

🧠💫🔊 We are looking for postdocs interested in the abstract mechanisms underlying social cognition. Modelling, fMRI and non-invasive ultrasound, a new deep-brain stimulation method.

Please RT

www.ucl.ac.uk/work-at-ucl/...
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
August 7, 2025 at 2:25 PM
Reposted by Miriam Klein-Flügge 🧠
I am delighted to announce registration and abstract submission is open for "The Mechanistic Basis of Foraging 2025" to be held at the Edgbaston Park Hotel, University of Birmingham, UK on 3-5th November 2025. uobevents.eventsair.com/the-mechanis...
Homepage - The Mechanistic Basis of Foraging
uobevents.eventsair.com
July 4, 2025 at 8:50 AM
I had an absolutely amazing and inspiring time during my first visit to Nijmegen @dondersinst.bsky.social this week! Thanks so much @lennartverhagen.bsky.social for the invite and for all the many great discussions about transcranial ultrasound 🥳🥳🥳
June 14, 2025 at 10:11 AM
Reposted by Miriam Klein-Flügge 🧠
As well as a new name, OxCIN also has a brand new Director: Karla Miller! @fmrib-karla.bsky.social We are grateful for 10 years of superb leadership by Heidi Johansen-Berg @heidijoberg.bsky.social and excited to see the new ideas Karla will bring. More about Karla: oxcin.ox.ac.uk/people/karla...
April 28, 2025 at 5:40 PM
Reposted by Miriam Klein-Flügge 🧠
We're excited to announce that WIN is now the Oxford University Centre for Integrative Neuroimaging: OxCIN! Our mission: developing and deploying neuroimaging and related technology to solve big challenges in basic neuroscience and brain health. oxcin.ox.ac.uk/about/vision
April 28, 2025 at 4:23 PM
Reposted by Miriam Klein-Flügge 🧠
I don’t dare to tell you how many years this took, but the project that I started as a MSc intern and kept working on throughout my PhD is now finally published: www.nature.com/articles/s44... [1/9]
How mood-related physiological states bias economic decisions - Communications Psychology
Brief inductions of happiness versus sadness bias unrelated economic choices towards more rewarded but more costly options. This choice bias is predicted by a mood proxy reconstructed from physiologic...
www.nature.com
April 8, 2025 at 9:56 AM
Reposted by Miriam Klein-Flügge 🧠
New paper from our lab now in @nature.com . We show that our brains use basis functions or "building blocks" to navigate social interactions. Rather than tracking every individual separately, social information is compressed into patterns that can be flexibly combined. www.nature.com/articles/s41...
Basis functions for complex social decisions in dorsomedial frontal cortex - Nature
A study combining group decision-making tasks with fMRI shows that the brain’s dorsomedial prefrontal cortex uses basis functions, similar to those in the visual, motor and spatial domains, to re...
www.nature.com
March 13, 2025 at 8:43 AM
Had a really fun time today at our local primary school with 9-10 year-olds as part of Brain Awareness Week. I was pretty impressed with their models showing how learning strengthens synapses 🥳☺️
March 13, 2025 at 2:56 PM
Reposted by Miriam Klein-Flügge 🧠
I'm thrilled to share our study, on the longitudinal impact of diet quality and waist-to-hip ratio (WHR) on 🧠 brain health in ageing, which has now been published in JAMA Network Open! - supervised by @sanasuri.bsky.social @oxxpat.bsky.social & @mkflugge.bsky.social jamanetwork.com/journals/jam...
March 12, 2025 at 4:31 PM
Given more and more people are transitioning over to Bluesky these days, I thought it might be worth re-sharing this transcranial focused ultrasound starter pack for those who haven't seen it yet: go.bsky.app/EjjWSUy

I would love to add you if you work in this field! Please let me know 😀
January 28, 2025 at 11:36 PM
New paper out in @pnas.org today with lovely colleagues including Hailey Trier, Nima Khalighinejad, @caro-harbison.bsky.social, @marklaubach.bsky.social, Jacquie Scholl & Matthew Rushworth (most not on BlueSky yet!) 

www.pnas.org/doi/epub/10....
A distributed subcortical circuit linked to instrumental information-seeking about threat
www.pnas.org
January 16, 2025 at 7:26 PM
Congratulations to @sankalpgarud.bsky.social on our lab for passing your PhD viva today!!! Huge well-done to you 🥳🥳🥳
November 26, 2024 at 10:08 PM
Super excited that lots of ultrasound neuromodulation people are slowly appearing here. I found several key people today. Welcome to those who joined recently 👋
November 19, 2024 at 10:37 PM
Reposted by Miriam Klein-Flügge 🧠
I'm extremely happy to share our study on hypothalamus functional connectivity & stress now out in ‪@NatureC‪omms - with Miriam Klein-Flügge, Sana Suri Klaus Ebmeier and Matthew Rushworth 
‪@OxfordWIN ‪@OxPsychiatry‪ @OxExpPsy @UniofOxford ‪@MPI_CBS
www.nature.com/articles/s41...
March 19, 2024 at 8:54 AM
I'm still missing lots of transcranial ultrasound neuromod folks on BlueSky, so trying to create a starter pack that I hope we can add many people to in the next weeks... please spread the word and let me know who I have missed out!

go.bsky.app/EjjWSUy
November 17, 2024 at 6:08 PM
Reposted by Miriam Klein-Flügge 🧠
Looking for inspirational women in neuroscience to follow? We made a starter pack of Stories of WiN interviewees and our team members! 💜 #WomenInNeuro #StoriesOfWiN

go.bsky.app/PCteLM8
November 13, 2024 at 3:07 AM
I have been a bit slow to make it here, but it seems about time to (finally!) join my fellow neuroscientists here - my first post on BlueSky 🥳
November 17, 2024 at 2:55 PM