Steve Middleton
@middletonsj.bsky.social
Post Doc • Bennett Lab • Pain and Sensory Biology • Research Fellow, @WolfsonCollege • University of Oxford • 🏳️🌈
We've found a new gene linked to chronic pain in humans! The gene SLC45A4 encodes (the long-awaited) neuronal polyamine transporter, which is important for pain signalling in nerves. We hope this discovery might lead to new chronic pain treatments in the future!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
SLC45A4 is a pain gene encoding a neuronal polyamine transporter - Nature
The SLC45A4 gene encodes a neuronal polyamine transporter and is linked to pain response in humans and mice.
www.nature.com
August 21, 2025 at 12:16 PM
We've found a new gene linked to chronic pain in humans! The gene SLC45A4 encodes (the long-awaited) neuronal polyamine transporter, which is important for pain signalling in nerves. We hope this discovery might lead to new chronic pain treatments in the future!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Steve Middleton
Our paper on SLC45A4 is out now in @nature.com! The orphan SLC45A4 transporter is a polyamine transporter involved in chronic pain signalling!
SLC45A4 is a pain gene encoding a neuronal polyamine transporter - Nature
The SLC45A4 gene encodes a neuronal polyamine transporter and is linked to pain response in humans and mice.
www.nature.com
August 21, 2025 at 11:05 AM
Our paper on SLC45A4 is out now in @nature.com! The orphan SLC45A4 transporter is a polyamine transporter involved in chronic pain signalling!
Reposted by Steve Middleton
📣 NEW: Breakthrough discovery of a genetic link to pain co-led by NDCN's Prof David Bennett and Prof Simon Newstead @oxfordbiochemistry.bsky.social
The results of the research, published in @nature.com, could lead to a promising new target for the treatment of #chronicpain.
The results of the research, published in @nature.com, could lead to a promising new target for the treatment of #chronicpain.
August 21, 2025 at 11:11 AM
📣 NEW: Breakthrough discovery of a genetic link to pain co-led by NDCN's Prof David Bennett and Prof Simon Newstead @oxfordbiochemistry.bsky.social
The results of the research, published in @nature.com, could lead to a promising new target for the treatment of #chronicpain.
The results of the research, published in @nature.com, could lead to a promising new target for the treatment of #chronicpain.