Mireille Farjo
@mfarjo.bsky.social
PhD candidate at UIUC, studying viral evolution (she/her)
Reposted by Mireille Farjo
Check out @lizthayer.bsky.social's new preprint exploring factors that influence cell-to-cell heterogeneity in interferon (IFN) induction potential!
Single-cell heterogeneity in interferon induction potential is heritable and governed by variation in cell state https://www.biorxiv.org/content/10.64898/2025.12.09.693293v1
December 12, 2025 at 10:12 PM
Check out @lizthayer.bsky.social's new preprint exploring factors that influence cell-to-cell heterogeneity in interferon (IFN) induction potential!
Reposted by Mireille Farjo
Finally, it's up on bioRxiv! It's been a rewarding journey shaping this story. My deepest gratitude to @vignuzzilab.bsky.social and @christopherbrooke.bsky.social for their incredible support, and to the @mcbillinois.bsky.social & @astar-idlabs.bsky.social for enabling this research
First big piece of research from our SG lab: Fadi's work with Chris Brooke's lab. Flu serially passaged 80X selects a defective genome with improved competition, but is nonviable as a full virus!
Notable improvement & safety for DVGs as antiviral RNA therapies!
www.biorxiv.org/content/10.1...
Notable improvement & safety for DVGs as antiviral RNA therapies!
www.biorxiv.org/content/10.1...
Longitudinal analysis of influenza A virus deletion-containing viral genomes reveals key determinants of co-evolutionary dynamics and interference
The substantial genetic diversity generated during influenza A virus replication facilitates both evasion of pre-existing host immunity and cross-species emergence. A major contributor to this diversi...
www.biorxiv.org
November 4, 2025 at 11:02 AM
Finally, it's up on bioRxiv! It's been a rewarding journey shaping this story. My deepest gratitude to @vignuzzilab.bsky.social and @christopherbrooke.bsky.social for their incredible support, and to the @mcbillinois.bsky.social & @astar-idlabs.bsky.social for enabling this research
Reposted by Mireille Farjo
No better reason to join Bluesky then to say the first chapter of my PhD is out as a preprint! New surgeonfish phylogeny, ecomorphological relationships, evolutionary shape correlations-with NEW method to accurately account for phylogenetic covariation among shapes!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Phylogenetic relationships and the evolution of fin and body shape in the surgeonfishes
Patterns of evolutionary change in the fin and body shapes of fishes are strongly related to dietary ecology and locomotor mechanisms, and associations between shapes affects ecomorphological relation...
www.biorxiv.org
October 11, 2025 at 12:44 PM
No better reason to join Bluesky then to say the first chapter of my PhD is out as a preprint! New surgeonfish phylogeny, ecomorphological relationships, evolutionary shape correlations-with NEW method to accurately account for phylogenetic covariation among shapes!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Mireille Farjo
More than 1800 detainees are missing after the closure of Alligator Alcatraz. Their families and lawyers can’t find them and they’ve vanished from the ICE database. Feels like this should be a much bigger story www.miamiherald.com/news/local/i...
Hundreds of Alligator Alcatraz detainees drop off the grid after leaving site
As of the end of August, the whereabouts of two-thirds of more than 1,800 men detained at Alligator Alcatraz during the month of July could not be determined by the Miami Herald.
www.miamiherald.com
September 23, 2025 at 5:39 PM
More than 1800 detainees are missing after the closure of Alligator Alcatraz. Their families and lawyers can’t find them and they’ve vanished from the ICE database. Feels like this should be a much bigger story www.miamiherald.com/news/local/i...
Reposted by Mireille Farjo
TreeSort is out at MBE! Fresh off the press so DOI below is not yet working, but you can find the article here: academic.oup.com/mbe/article/...
💡If you want to apply it to your data - please see the tutorial here github.com/flu-crew/Tre...
💡If you want to apply it to your data - please see the tutorial here github.com/flu-crew/Tre...
August 11, 2025 at 1:34 PM
TreeSort is out at MBE! Fresh off the press so DOI below is not yet working, but you can find the article here: academic.oup.com/mbe/article/...
💡If you want to apply it to your data - please see the tutorial here github.com/flu-crew/Tre...
💡If you want to apply it to your data - please see the tutorial here github.com/flu-crew/Tre...
Reposted by Mireille Farjo
Check out @mfarjo.bsky.social's new preprint where she uses a simulation-based approach to explore the evolutionary consequences of genetic mixing through co-infection for segmented viruses:
www.biorxiv.org/content/10.1...
hope you like it!
www.biorxiv.org/content/10.1...
hope you like it!
The fitness consequences of coinfection and reassortment for segmented viruses depend upon viral genetic structure
Cellular coinfection between multiple virions is a common feature of viral infections. The collective virus-virus interactions enabled by these coinfections can influence the fitness of viral populati...
www.biorxiv.org
July 29, 2025 at 8:46 PM
Check out @mfarjo.bsky.social's new preprint where she uses a simulation-based approach to explore the evolutionary consequences of genetic mixing through co-infection for segmented viruses:
www.biorxiv.org/content/10.1...
hope you like it!
www.biorxiv.org/content/10.1...
hope you like it!
Reposted by Mireille Farjo
“Department of Homeland Security officers, who are posted outside the woman's Tucson Medical Center hospital room, are refusing to let the new mother speak to a lawyer, as she's requested” tucson.com/news/local/b...
Border agents posted at Tucson maternity ward to quickly deport migrant mom
The Guatemalan woman arrested in the Arizona desert will be given the choice taking her newborn — a US citizen born Wednesday at Tucson Medical Center — with her when
tucson.com
May 2, 2025 at 9:27 PM
“Department of Homeland Security officers, who are posted outside the woman's Tucson Medical Center hospital room, are refusing to let the new mother speak to a lawyer, as she's requested” tucson.com/news/local/b...
Reposted by Mireille Farjo
I feel like we need to keep saying this because it’s so insane: This is a legal U.S. resident who has been detained for over a month now for his political opinions.
The Department of Homeland Security denied Mahmoud Khalil permission to attend the birth of his first child, who was delivered at a New York hospital on Monday, according to emails reviewed by The New York Times.
Mahmoud Khalil’s Son Arrives After ICE Refuses to Let Him Attend Birth
Mr. Khalil, a permanent resident detained in Louisiana, had requested a monitored furlough for the birth. His request was denied in less than an hour.
www.nytimes.com
April 22, 2025 at 1:28 AM
I feel like we need to keep saying this because it’s so insane: This is a legal U.S. resident who has been detained for over a month now for his political opinions.
Reposted by Mireille Farjo
Why can't these viruses be friends?
In a new study from her PhD @cvrinfo.bsky.social, #AnnaSims shows that #SARS-CoV-2 infections segregate into distinct microdomains as they spread. But why? (1/N)
journals.asm.org/doi/10.1128/...
In a new study from her PhD @cvrinfo.bsky.social, #AnnaSims shows that #SARS-CoV-2 infections segregate into distinct microdomains as they spread. But why? (1/N)
journals.asm.org/doi/10.1128/...
March 21, 2025 at 1:47 PM
Why can't these viruses be friends?
In a new study from her PhD @cvrinfo.bsky.social, #AnnaSims shows that #SARS-CoV-2 infections segregate into distinct microdomains as they spread. But why? (1/N)
journals.asm.org/doi/10.1128/...
In a new study from her PhD @cvrinfo.bsky.social, #AnnaSims shows that #SARS-CoV-2 infections segregate into distinct microdomains as they spread. But why? (1/N)
journals.asm.org/doi/10.1128/...
Reposted by Mireille Farjo
@joelrc.bsky.social 's paper on differences between the seasonal H1N1 and H3N2 lineages in their relative capacity to antagonize IFN induction and signaling at the single cell level is out now in PLOS Pathogens:
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Seasonal influenza a virus lineages exhibit divergent abilities to antagonize interferon induction and signaling
Author summary Successful replication and transmission of influenza A viruses (IAVs) requires effective subversion of the innate immune response. We developed a new single cell method to examine the i...
journals.plos.org
December 12, 2024 at 6:58 PM
@joelrc.bsky.social 's paper on differences between the seasonal H1N1 and H3N2 lineages in their relative capacity to antagonize IFN induction and signaling at the single cell level is out now in PLOS Pathogens:
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Reposted by Mireille Farjo
Excited to *finally* have @mfarjo.bsky.social 's fantastic paper on SARS-CoV-2 within-host evolutionary dynamics during acute infection published at JVI: journals.asm.org/doi/10.1128/...
journals.asm.org
January 5, 2024 at 12:29 AM
Excited to *finally* have @mfarjo.bsky.social 's fantastic paper on SARS-CoV-2 within-host evolutionary dynamics during acute infection published at JVI: journals.asm.org/doi/10.1128/...