Marios Chatzigeorgiou
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mchatzigeorgiou.bsky.social
Marios Chatzigeorgiou
@mchatzigeorgiou.bsky.social
160 followers 350 following 5 posts
Neurobiologist, Group Leader @msarscentre.bsky.social
https://www.chatzigeorgioulab.com/
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mchatzigeorgiou.bsky.social
Marios Chatzigeorgiou @mchatzigeorgiou.bsky.social · Apr 22
Super excited for our new preprint on the role of tissue mechanics on the neurophysiology and behavior of Ciona. A tour de force by @midlangandreas.bsky.social and other lab members combining tension sensors, calcium imaging, optogenetic tools and of course behavior. More to come soon.
Reposted by Marios Chatzigeorgiou
oceanetourniere.bsky.social
Je suis ravie d’avoir participé à la chaîne YouTube Scienticfiz, créée par Gilles Gourio et ses élèves de collège ! Une belle initiative qui met à l’honneur de nombreuses femmes ayant suivi des études scientifiques et inspire les futures générations! 👩‍🔬✨
November 12, 2025 at 5:08 PM
Reposted by Marios Chatzigeorgiou
lionlchristiaen.bsky.social
Could not be more happy/proud/relieved to finally see this longstanding study published. Bluetorial to follow. @msarscentre.bsky.social
Cell cycle-driven transcriptome maturation confers multilineage competence to cardiopharyngeal progenitors | The EMBO Journal www.embopress.org/doi/full/10....
Cell cycle-driven transcriptome maturation confers multilineage competence to cardiopharyngeal progenitors | The EMBO Journal
imageimageDuring development, multipotent cardiopharyngeal progenitors express both cardiac and pharyngeal muscle transcriptional programs. This study in the tunicate Ciona shows that cell cycle-regul...
www.embopress.org
November 4, 2025 at 6:05 AM
Reposted by Marios Chatzigeorgiou
currentbiology.bsky.social
Mind over matter, matter over mind?

Check out our fine mini-special (mini by our standards) special issue on how #brain and #body interact.

🧠🕺

www.cell.com/current-biol...
October 28, 2025 at 6:52 AM
Reposted by Marios Chatzigeorgiou
socdevbio.bsky.social
Ascidians (Ciona intestinalis)🪸Our distant chordate cousins! 🌊 Simple sea squirts that reveal how vertebrate body plans evolved 🧬 A key model for notochord formation, neural induction, and cell lineage mapping 📸 Video by MBL Embryology 2019 #ModelMonday #DevBio #EvoDevo
October 28, 2025 at 12:46 AM
Reposted by Marios Chatzigeorgiou
pawelburkhardt.bsky.social
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience

Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E

@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 6:48 PM
Reposted by Marios Chatzigeorgiou
mariasachkova.bsky.social
🪸 🪸 🪸 Postdoc position in my group at Bristol to study the role of venom in surviving environmental stress in corals! 🪸 Interested in venom biochemistry and coral ecology?Please apply by November 24!
@bristolbiosci.bsky.social
www.bristol.ac.uk/jobs/find/de...
October 27, 2025 at 12:43 PM
Reposted by Marios Chatzigeorgiou
lionlchristiaen.bsky.social
See you all in #BeautifulRoscoff next Spring 🙌🏻
bardinlab.bsky.social Bardin Lab @bardinlab.bsky.social · 24d
I am very excited to announce the opening of the submission site for the upcoming Conférences Jacques Monod on Developmental Biology, May 18-22, 2026 cjm.sb-roscoff.fr/en/conferenc...
@lionlchristiaen.bsky.social and I have an exciting program of speakers and slots for selected short talks, etc.
October 23, 2025 at 1:45 PM
Reposted by Marios Chatzigeorgiou
venky-vnm.bsky.social
📣 Fully-funded PhD opportunity in my Lab @bristolbiosci.bsky.social @bristoluni.bsky.social
🔬We will explore how coral larvae sense their environment and guide settlement.
Check out the details! 👇
www.findaphd.com/phds/project...

#Coral #SensoryEcology #PhD #MarineScience
October 21, 2025 at 6:57 PM
Reposted by Marios Chatzigeorgiou
emclaereboudt.bsky.social
Tiny sea cucumbers, big mysteries! 🪱
Out sampling for my MSCA project SensHolo at the @msarscentre.bsky.social, at the University of Bergen, 🇳🇴— exploring how these mini echinoderms sense their world.
Plus a few bonus echinoderms! 🌊✨
October 20, 2025 at 10:32 AM
Reposted by Marios Chatzigeorgiou
oceanetourniere.bsky.social
Still can’t quite believe it 💫 I’ve received the L’Oréal-UNESCO For Women in Science “Jeunes Talents” France 2025 award!
I’m so deeply honored — this recognition means so much to me, both as a scientist and as a woman who loves research. 💙🔬 1/3
October 9, 2025 at 1:08 PM
Reposted by Marios Chatzigeorgiou
micromotility.bsky.social
Very sad to hear that Sir John Gurdon, former Master of Magdalene College, has passed away at the age of 92. www.cam.ac.uk/research/new...

Here is a powerful reminder that you should never give up on your dreams.
October 7, 2025 at 3:34 PM
Reposted by Marios Chatzigeorgiou
msarscentre.bsky.social
Huge congratulations to postdoc Guillaume Poncelet @guillaumeponcelet.bsky.social who was awarded a UiB Early Idea innovation grant 🤩🎉 Inspired by his work in the @lionlchristiaen.bsky.social lab, he will be developing a new product derived from naturally occurring compounds 🔬 Read more below ⤵️
Michael Sars Centre researcher awarded UiB Idé innovation grant
Guillaume Poncelet, postdoctoral researcher in the Christiaen group, will receive funding from the UiB Idé innovation program to develop a novel product inspired by marine life.
tinyurl.com
September 17, 2025 at 1:19 PM
Reposted by Marios Chatzigeorgiou
skatsanevakis.bsky.social
Our Editorial concludes a Research Topic with 26 insightful articles on how #ecosystems respond to human pressures & #ClimateChange: www.frontiersin.org/journals/mar...

Explore the full collection: www.frontiersin.org/research-top...

#MarineScience #Conservation #Biodiversity #MarineEcology
🧪🌍🌐🌊
Frontiers | Understanding the Response of Ecosystems to Increasing Human Pressures and Climate Change – Management Options
The human footprint on the world's oceans has grown significantly in recent years, exerting immense pressure on marine ecosystems and leading to a decline in...
www.frontiersin.org
September 17, 2025 at 6:52 AM
Reposted by Marios Chatzigeorgiou
rnadoctor.bsky.social
This was a collaborative project with Alberto Stolfi at GeorgiaTech and @lionlchristiaen.bsky.social at @nyu.edu, @msarscentre.bsky.social, and @unibergen.bsky.social .

Alberto also created a song for this paper, in the style of 80s hard rock. Check it out 🔈
September 16, 2025 at 7:13 PM
Reposted by Marios Chatzigeorgiou
lionlchristiaen.bsky.social
Another tour-de-force paper led by Bluesky-free Alberto Stolfi, who pushed it through the finish line in his lab at Georgia Tech 🙌🏻🙏🏻 From transcription to alternative RNA splicing, AchR aggregation and neuromuscular junction formation #Ciona neurodevelopment at its best 🤩 @msarscentre.bsky.social
plosbiology.org PLOS Biology @plosbiology.org · Sep 15
Neuron-specific splicing of Agrin by Nova is essential for AChR clustering at the NMJ. @rnadoctor.bsky.social @lionlchristiaen.bsky.social &co show that this pathway is conserved in tunicates & that the transcription factor Ebf is a key activator of Nova expression @plosbiology.org 🧪 plos.io/3VhTwig
Top left: Two-color double ISH of Nova (green) and Islet (magenta) showing co-expression in the bilaterally symmetric Motor Neuron 2 (MN2) pair of cells (arrows). Note that Nova mRNA distribution appears more nuclear than Islet in these cells at this stage. Top right: Summary model diagram of a conserved Nova-Agrin-Lrp4 pathway for AChR clustering in Ciona. Upper panel: Summary of conserved pathway, and previously unidentified Ebf-Nova regulatory connection identified in Ciona. Lower panel: Model of proposed mechanism for Ciona Nova-dependent alternative Agrin splicing via binding of KH1 and KH2 domains to two YCAY-rich NISEs identified in the intron 3′ to the Z exons (though not known in what exact orientation or configuration). Inhibitory effect of KH3 domain is relieved by the N- and C-termini. Diagram not drawn to scale. Bottom: Neural-specific CRISPR-mediated disruption of Agrin using sgRNAs results in loss of Acetylcholine receptor A1::GFP clusters (AChRA1::GFP, green) in tail muscles, driven by the Tbx6-r.b promoter. Motor neuron axons labeled by VAChT > Unc-76::mCherry in magenta.
September 15, 2025 at 11:52 AM
Reposted by Marios Chatzigeorgiou
skatsanevakis.bsky.social
New preprint! 🎶🌊 We built a low-cost (€50) passive acoustic toolkit for underwater recordings—robust, DIY, and ideal for #CitizenScience & education. Testing shows strong potential for large-scale #soundscape #monitoring.
www.preprints.org/manuscript/2...
#MarineEcology #hydroacoustics 🧪🌍🌐
September 16, 2025 at 6:56 PM
Reposted by Marios Chatzigeorgiou
evodevogenomeub.bsky.social
Congrats Esteve 👏🏻👏🏻 for your excellent defense of your TFG studying how marine noise contamination affects #Oikopleura, #deuteronoise project cosupervised by @evadevo.bsky.social @esteeve.bsky.social @geneticsub.bsky.social @irbio-ub.bsky.social @ub.edu
September 9, 2025 at 2:30 PM
Reposted by Marios Chatzigeorgiou
thibautbrunet.bsky.social
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
Flagellar gliding in choanoflagellates
Freire-Delgado and Brunet discover a new mode of cell motility in choanoflagellates, the closest relatives of animals. Under mild confinement, choanoflagellate move over surfaces without cell deformat...
www.cell.com
September 9, 2025 at 6:12 PM
Reposted by Marios Chatzigeorgiou
msarscentre.bsky.social
"A reminder of why I fell in love with biology in the first place" 🔬✨ This summer, PhD candidate Max Jordi Makem Pekouankouang from the @lionlchristiaen.bsky.social lab participated in the Embryology course at @mblscience.bsky.social. He shares how this experience enriched his approach to science ⤵️
A transformative embryology summer course
This summer, PhD candidate Max Jordi Makem Pekouankouang from the Christiaen group at the Michael Sars Centre attended the prestigious Embryology summer course at the Marine Biological Laboratory in W...
shorturl.at
September 4, 2025 at 1:53 PM
Reposted by Marios Chatzigeorgiou
andrewclin.bsky.social
Excited to share our latest work - expressing the bacterial sodium channel in fly Kenyon cells surprisingly *decreases* their excitability, thanks partly to decreased endogenous sodium channels. This prevents learning and decreases odor-evoked calcium influx doi.org/10.1113/JP28...
Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells
Abstract figure legend: We tested the effects of expressing the bacterial voltage-gated sodium channel NaChBac in the Kenyon cells of the Drosophila memory centre, the mushroom body. NaChBac expressi...
doi.org
September 1, 2025 at 4:50 PM
Reposted by Marios Chatzigeorgiou
ulrichtechnau.bsky.social
Finally, the excellent postdoc work of Emmanuel Haillot is out, where he dissected the integration of Wnt, MAPK and Notch signaling in defining mesoderm and endoderm identities in the diploblast Nematostella. Strikingly similar to sea urchins. www.nature.com/articles/s41...
August 29, 2025 at 9:04 PM
Reposted by Marios Chatzigeorgiou
micromotility.bsky.social
Complex behaviour is not limited to animals! Here we map the entire spectrum of waveforms dynamics on a quadriflagellate single cell with 4x 70um (!) #cilia, to a low dimensional behavioural manifold with surprising structure! #protistsonsky

All revealed in our new preprint doi.org/10.1101/2025...
August 23, 2025 at 9:20 AM
Reposted by Marios Chatzigeorgiou
msarscentre.bsky.social
Congratulations @appygenetics.bsky.social on a new preprint 🤩 🧪 Read the whole paper below ⤵️
appygenetics.bsky.social Chourrout lab @appygenetics.bsky.social · Aug 18
Check the last preprint from @simonhenriet.bsky.social & colleagues‬. By studying appendicularians, they revealed the events that permitted non-canonical splicing in these organisms:

. Duplication & divergence of U2AF splicing factors
. Gain & loss of chemical modifications on the spliceosomal RNA
Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and re-patterning of snRNA m6A modification
In eukaryotes, splicing is a critical step of gene expression that produces transcripts competent for protein synthesis by removing introns from pre-mRNA. The spliceosome defines target splice sites b...
www.biorxiv.org
August 21, 2025 at 8:57 AM
Reposted by Marios Chatzigeorgiou
emclaereboudt.bsky.social
🌊🧪 Big day at #chemecol2025!
I presented my talk:
“Chemical cues & larval behaviour in the tunicate Ciona intestinalis 🪸✨

I had the pleasure of chairing the Aquatic Chemical Ecology session — featuring amazing talks on annelids, cnidarians, oysters, and red algae. 🌿🦪🪼🪱
August 20, 2025 at 6:45 AM