Alzheimer’s disease features amyloid-beta (Abeta) plaques, ApoE-driven amyloid buildup, and Caveolin1-modulated APP processing. IBA1 marks activated microglia clustering near plaques, fueling immune and inflammatory responses that accelerate neurodegeneration.
#FluorescenceFriday
#Neuroscience

Indirect immunostaining of astrocytes surrounding a blood vessel in the mouse brain with GFAP 🟠. Nuclei have been visualized by DAPI staining 🔵.
#bloodbrainbarrier
#FluorescenceFriday

Indirect immunostaining of a mouse brain section with Aquaporin4 🔴 and Occludin 🟢. Nuclei have been visualized by DAPI staining 🔵.

#bloodbrainbarrier
#FluorescenceFriday

Immunostaining of a mouse brain (hippocampus) section with GluT1 🟣 and ALDH1L1 🟢. Nuclei have been visualized by DAPI staining 🔵.

#bloodbrainbarrier
#FluorescenceFriday

Immunostaining of a Alzheimer's disease mouse brain with Aquaporin 4 🔴, P2Y12 🟢, APP 🟡 and Abeta 🟣.

#FluorescenceFriday
#neuroscience

Immunostaining of a rat brain cortex with IBA1 🔴. Nuclei have been visualized by DAPI staining 🔵.
#FluorescenceFriday

Immunostaining of a mouse brain cortex with von Willebrand factor ⚪ and Caveolin1 🔵. Nuclei have been visualized by DAPI staining 🟣.

#bloodbrainbarrier #FluorescenceFriday

Immunostaining of a mouse brain with ATP13A5 (red) and GFAP (cyan). Nuclei have been visualized by DAPI staining (blue).

#bloodbrainbarrier
#FluorescenceFriday
#Pericytes

Indirect immunostaining of rat hippocampus neurons with
β-Actin (red), Giantin (green) and α-Tubulin (blue). Nuclei have been visualized by DAPI staining (cyan).​

#FluorescenceFriday
#neuroscience
#CellBiology

Immunostaining of a mouse brain blood vessel with Caveolin1 🔴 and Aquaporin4 🟢. Nuclei have been visualized by DAPI staining 🔵.

#bloodbrainbarrier
#FluorescenceFriday

Mouse retina staining with
Kir4.1 ⚪
Prox1🔴
Calbindin D28k🟢
Nuclei 🔵

#bloodretinalbarrier
#FluorescenceFriday

A new #FluorescenceFriday picture.
Indirect immunostaining of a rat hippocampus neuron with Somatostatin-28 🔴 and MAP2🟢. Nuclei have been visualized by DAPI 🔵.​

There are lots of us missing, but so many joining so quickly

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(microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)

Immunostaining of a mouse brain blood vessel with Aquaporin4 🔴 and Occludin 🟢. Nuclei have been visualized by DAPI staining 🔵.
#FluorescenceFriday #bloodbrainbarrier

Immunostaining of a mouse brain blood vessel with Collagen type 4 (cyan) and GFAP (orange) Nuclei have been visualized by DAPI staining (blue).
#FluorescenceFriday
#bloodbrainbarrier

L-type amino transporter1 🔴
Aquaporin4 🟢
DAPI🔵