Roy Matkovic
@matkovic.bsky.social
CNRS researcher- Group Leader Virus/Chromatin Interface, HUSH complex and other cool stuff @Institut Cochin
Reposted by Roy Matkovic
Pleased to announce launching Institut Cochin Foundation, on Sept. 18 at 6 p.m., upon registration, either in the Rosalind Franklin room, 22 rue Méchain, Paris or via video conference: presentation of @institutcochin.bsky.social, meet researchers and call for donations-thanks for your support!
September 6, 2025 at 6:46 AM
Pleased to announce launching Institut Cochin Foundation, on Sept. 18 at 6 p.m., upon registration, either in the Rosalind Franklin room, 22 rue Méchain, Paris or via video conference: presentation of @institutcochin.bsky.social, meet researchers and call for donations-thanks for your support!
Reposted by Roy Matkovic
Zeus had his Hydra ⚔️, now Toxoplasma has its own.
Meet Hydra: not a monster, but a brand-new protein domain.
It multimerizes like crazy & rewrites the chromatin landscape 🧬 in Toxoplasma.
Our team and colleagues from @embl.org #Grenoble just dropped the preprint 👉
www.biorxiv.org/content/10.1...
Meet Hydra: not a monster, but a brand-new protein domain.
It multimerizes like crazy & rewrites the chromatin landscape 🧬 in Toxoplasma.
Our team and colleagues from @embl.org #Grenoble just dropped the preprint 👉
www.biorxiv.org/content/10.1...
September 6, 2025 at 9:03 AM
Zeus had his Hydra ⚔️, now Toxoplasma has its own.
Meet Hydra: not a monster, but a brand-new protein domain.
It multimerizes like crazy & rewrites the chromatin landscape 🧬 in Toxoplasma.
Our team and colleagues from @embl.org #Grenoble just dropped the preprint 👉
www.biorxiv.org/content/10.1...
Meet Hydra: not a monster, but a brand-new protein domain.
It multimerizes like crazy & rewrites the chromatin landscape 🧬 in Toxoplasma.
Our team and colleagues from @embl.org #Grenoble just dropped the preprint 👉
www.biorxiv.org/content/10.1...
Reposted by Roy Matkovic
New paper from our lab! We found that LINE-1 transposons contribute to early human brain development.
Funded by @asapresearch.parkinsonsroadmap.org
www.cell.com/cell-genomic...
Funded by @asapresearch.parkinsonsroadmap.org
www.cell.com/cell-genomic...
LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development
Adami et al. demonstrate that evolutionarily young L1s are expressed in human pluripotent
stem cells and are dynamically regulated throughout neural differentiation. The study
examines the role of L1s...
www.cell.com
August 23, 2025 at 9:47 AM
New paper from our lab! We found that LINE-1 transposons contribute to early human brain development.
Funded by @asapresearch.parkinsonsroadmap.org
www.cell.com/cell-genomic...
Funded by @asapresearch.parkinsonsroadmap.org
www.cell.com/cell-genomic...
Reposted by Roy Matkovic
Still 1 month to submit your abstract! Don’t miss the chance to participate in our next #POHaD symposium. Join us onsite/virtually on Oct 16th, 2025 at @institutcochin.bsky.social (Paris 🇫🇷). Registration is free but mandatory 🗓️
@juliecocquet.bsky.social #epigenetics #dohad #offspringhealth
@juliecocquet.bsky.social #epigenetics #dohad #offspringhealth
August 7, 2025 at 8:58 AM
Still 1 month to submit your abstract! Don’t miss the chance to participate in our next #POHaD symposium. Join us onsite/virtually on Oct 16th, 2025 at @institutcochin.bsky.social (Paris 🇫🇷). Registration is free but mandatory 🗓️
@juliecocquet.bsky.social #epigenetics #dohad #offspringhealth
@juliecocquet.bsky.social #epigenetics #dohad #offspringhealth
Thrilled to receive an @agencerecherche.bsky.social JCJC grant to explore chromatin-driven antiviral defenses and to revisit some of the underlying principles behind the HUSH complex. Exciting times ahead @institutcochin.bsky.social
July 3, 2025 at 6:59 PM
Thrilled to receive an @agencerecherche.bsky.social JCJC grant to explore chromatin-driven antiviral defenses and to revisit some of the underlying principles behind the HUSH complex. Exciting times ahead @institutcochin.bsky.social
Reposted by Roy Matkovic
Postdoc positions open in my lab (Francis Crick Institute) to study
1. initiation of DNA replication.
2. chromatin replication/epigenetic inheritance.
Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.
Deadline 3 August 2025.
crick.wd3.myworkdayjobs.com/External/job...
1. initiation of DNA replication.
2. chromatin replication/epigenetic inheritance.
Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.
Deadline 3 August 2025.
crick.wd3.myworkdayjobs.com/External/job...
June 20, 2025 at 9:38 AM
Postdoc positions open in my lab (Francis Crick Institute) to study
1. initiation of DNA replication.
2. chromatin replication/epigenetic inheritance.
Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.
Deadline 3 August 2025.
crick.wd3.myworkdayjobs.com/External/job...
1. initiation of DNA replication.
2. chromatin replication/epigenetic inheritance.
Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.
Deadline 3 August 2025.
crick.wd3.myworkdayjobs.com/External/job...
I had the privilege of defending my HDR today at @institutcochin.bsky.social, before an outstanding jury of experts @nchazal.bsky.social, @lucievirevolte.bsky.social,Rosemary Kiernan, Stephane Emiliani, Marc Lavigne. I am deeply grateful for their stimulating questions, and generous feedback.
June 25, 2025 at 2:31 PM
I had the privilege of defending my HDR today at @institutcochin.bsky.social, before an outstanding jury of experts @nchazal.bsky.social, @lucievirevolte.bsky.social,Rosemary Kiernan, Stephane Emiliani, Marc Lavigne. I am deeply grateful for their stimulating questions, and generous feedback.
Reposted by Roy Matkovic
Maîtriser la fin de la transcription : identification d'un mécanisme clé pour préserver l'intégrité du génome par @fabiennebejjani.bsky.social ! 🧬
🤝 @cnrs-idf-villejuif.bsky.social @inserm.fr @upcite.bsky.social @institutcochin.bsky.social
buff.ly/5hyNH7E
🤝 @cnrs-idf-villejuif.bsky.social @inserm.fr @upcite.bsky.social @institutcochin.bsky.social
buff.ly/5hyNH7E
Maîtriser la fin de la transcription : un mécanisme clé pour préserver l'intégrité du génome
La transcription des gènes est un processus qui permet de copier l’information génétique contenue dans l’ADN sous forme d’ARN.
www.insb.cnrs.fr
June 20, 2025 at 3:02 PM
Maîtriser la fin de la transcription : identification d'un mécanisme clé pour préserver l'intégrité du génome par @fabiennebejjani.bsky.social ! 🧬
🤝 @cnrs-idf-villejuif.bsky.social @inserm.fr @upcite.bsky.social @institutcochin.bsky.social
buff.ly/5hyNH7E
🤝 @cnrs-idf-villejuif.bsky.social @inserm.fr @upcite.bsky.social @institutcochin.bsky.social
buff.ly/5hyNH7E
Reposted by Roy Matkovic
📣 We are recruiting new group leaders in Innovative Biology!
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
May 28, 2025 at 12:12 PM
📣 We are recruiting new group leaders in Innovative Biology!
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information ⬇️
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
Reposted by Roy Matkovic
Discovery of a new key mechanism to preserve the integrity of the #genome!
Fabienne Bejjani et al. reveal that the SPT6 protein plays a central role in properly stopping transcription and avoiding the accumulation of abnormal transcripts.
CNRS/ Inserm/ UPC
institutcochin.fr/en/mastering...
Fabienne Bejjani et al. reveal that the SPT6 protein plays a central role in properly stopping transcription and avoiding the accumulation of abnormal transcripts.
CNRS/ Inserm/ UPC
institutcochin.fr/en/mastering...
Mastering transcription termination: a new key mechanism to preserve the integrity of the genome
Transcription termination by RNA polymerase II is essential to preserve genome integrity in eukaryotes. In their paper published in Nucleic Acids Research, the authors reveal that the SPT6 protein, in...
institutcochin.fr
May 21, 2025 at 10:55 AM
Discovery of a new key mechanism to preserve the integrity of the #genome!
Fabienne Bejjani et al. reveal that the SPT6 protein plays a central role in properly stopping transcription and avoiding the accumulation of abnormal transcripts.
CNRS/ Inserm/ UPC
institutcochin.fr/en/mastering...
Fabienne Bejjani et al. reveal that the SPT6 protein plays a central role in properly stopping transcription and avoiding the accumulation of abnormal transcripts.
CNRS/ Inserm/ UPC
institutcochin.fr/en/mastering...
Reposted by Roy Matkovic
#NSV2025 Two weeks left to register! The abstract submission/registration system on the website will CLOSE Friday, April 11, 2025. Visit www.negativestrandvirus.org/home
March 28, 2025 at 8:51 PM
#NSV2025 Two weeks left to register! The abstract submission/registration system on the website will CLOSE Friday, April 11, 2025. Visit www.negativestrandvirus.org/home
Reposted by Roy Matkovic
ARGONAUTES 2025
The grassroot meeting of Argonaute afficionados is looking for afficionados! Full coverage of Argonautes from prokaryotes to #RNAi, #piRNA and #microRNA Join us in Prague at @imgprague.bsky.social during 27-30/8, 2025. Registration, program and more info here:
argonautes.img.cas.cz
The grassroot meeting of Argonaute afficionados is looking for afficionados! Full coverage of Argonautes from prokaryotes to #RNAi, #piRNA and #microRNA Join us in Prague at @imgprague.bsky.social during 27-30/8, 2025. Registration, program and more info here:
argonautes.img.cas.cz
March 12, 2025 at 6:56 AM
ARGONAUTES 2025
The grassroot meeting of Argonaute afficionados is looking for afficionados! Full coverage of Argonautes from prokaryotes to #RNAi, #piRNA and #microRNA Join us in Prague at @imgprague.bsky.social during 27-30/8, 2025. Registration, program and more info here:
argonautes.img.cas.cz
The grassroot meeting of Argonaute afficionados is looking for afficionados! Full coverage of Argonautes from prokaryotes to #RNAi, #piRNA and #microRNA Join us in Prague at @imgprague.bsky.social during 27-30/8, 2025. Registration, program and more info here:
argonautes.img.cas.cz
Reposted by Roy Matkovic
Don't forget to register and submit your abstract for #NSV2025 in Montpellier! The abstract submission/registration system on the website will CLOSE Friday, April 11, 2025.
Visit www.negativestrandvirus.org/home
Visit www.negativestrandvirus.org/home
March 5, 2025 at 7:05 PM
Don't forget to register and submit your abstract for #NSV2025 in Montpellier! The abstract submission/registration system on the website will CLOSE Friday, April 11, 2025.
Visit www.negativestrandvirus.org/home
Visit www.negativestrandvirus.org/home
Reposted by Roy Matkovic
Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice https://www.biorxiv.org/content/10.1101/2025.02.26.640358v1
March 2, 2025 at 5:32 PM
Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice https://www.biorxiv.org/content/10.1101/2025.02.26.640358v1
Congratulations!
Woke up to an accepted manuscript today! 🥳 Grateful for everyone who supported this work. Excited to share our findings soon!!
February 20, 2025 at 4:12 PM
Congratulations!
Reposted by Roy Matkovic
Negative-Strand RNA Virus meeting #NSV2025 registration is now open!
Visit www.negativestrandvirus.org/home
Visit www.negativestrandvirus.org/home
February 17, 2025 at 10:21 AM
Negative-Strand RNA Virus meeting #NSV2025 registration is now open!
Visit www.negativestrandvirus.org/home
Visit www.negativestrandvirus.org/home
Reposted by Roy Matkovic
#BonneAnnée 🌟 Le #CNRS vous présente ses meilleurs vœux pour l'année 2025 !
#HappyNewYear 🌟 The French National Centre for Scientific Research (@cnrs.bsky.social) wishes you the very best for 2025!
#HappyNewYear 🌟 The French National Centre for Scientific Research (@cnrs.bsky.social) wishes you the very best for 2025!
January 1, 2025 at 2:23 PM
#BonneAnnée 🌟 Le #CNRS vous présente ses meilleurs vœux pour l'année 2025 !
#HappyNewYear 🌟 The French National Centre for Scientific Research (@cnrs.bsky.social) wishes you the very best for 2025!
#HappyNewYear 🌟 The French National Centre for Scientific Research (@cnrs.bsky.social) wishes you the very best for 2025!
Reposted by Roy Matkovic
Join us! Collaborative project between 3 labs at
Institut Pasteur on tick-borne flaviviruses
research.pasteur.fr/en/job/post-...
Institut Pasteur on tick-borne flaviviruses
research.pasteur.fr/en/job/post-...
November 18, 2024 at 8:52 PM
Join us! Collaborative project between 3 labs at
Institut Pasteur on tick-borne flaviviruses
research.pasteur.fr/en/job/post-...
Institut Pasteur on tick-borne flaviviruses
research.pasteur.fr/en/job/post-...
Reposted by Roy Matkovic
PhD opportunity in our lab at Edinburgh University! Analysing CRISPR screens for proviral and antiviral factors focusing on coronaviruses and influenza A virus. Using a mix of wet lab and computational approaches (full training provided).
#ViroSky #ImmunoSky
usher.ed.ac.uk/precision-me...
#ViroSky #ImmunoSky
usher.ed.ac.uk/precision-me...
Meta-analysis of genome wide functional screens to identify broad-spectrum antiviral and immuno-therapeutic targets
Precision Medicine Project - Meta-analysis of genome wide functional screens to identify broad-spectrum antiviral and immuno-therapeutic targets
usher.ed.ac.uk
November 15, 2024 at 3:31 AM
PhD opportunity in our lab at Edinburgh University! Analysing CRISPR screens for proviral and antiviral factors focusing on coronaviruses and influenza A virus. Using a mix of wet lab and computational approaches (full training provided).
#ViroSky #ImmunoSky
usher.ed.ac.uk/precision-me...
#ViroSky #ImmunoSky
usher.ed.ac.uk/precision-me...
Reposted by Roy Matkovic
Hey Skeeters, A big new batch of our
@fnucleosome.bsky.social
seminar videos have gone public in the past couple weeks! Here's a thread:
@fnucleosome.bsky.social
seminar videos have gone public in the past couple weeks! Here's a thread:
November 13, 2024 at 11:55 PM
Hey Skeeters, A big new batch of our
@fnucleosome.bsky.social
seminar videos have gone public in the past couple weeks! Here's a thread:
@fnucleosome.bsky.social
seminar videos have gone public in the past couple weeks! Here's a thread: