Jan Mašek
@maseklab.bsky.social
PI at CUNI Prague🇨🇿, former Karolinska Institutet🇸🇪 postdoc, Czexpat🌍. Notch & Wnt in development and disease 🔬🧫🐁. *All views my own; 🇪🇺🇺🇦 https://maseklab.org
15th PhD Conference in Dev Cell biology just started and it looks like another year packed with great science, opening with brilliant @ruibenedito.bsky.social keynote!
October 22, 2025 at 8:01 AM
15th PhD Conference in Dev Cell biology just started and it looks like another year packed with great science, opening with brilliant @ruibenedito.bsky.social keynote!
Reposted by Jan Mašek
👩🔬👨💻 Postdoc recruitment! 👨🔬👩💻
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Postdoctoral studies in next generation single cell lineage tracing of skin (scholarship)
Do you want to contribute to top quality medical research? A postdoctoral scholarship is available in the lab of Emma R Andersson at the Department of Cell and Molecular Biology, Karolinska Institutet
ki.varbi.com
September 27, 2025 at 7:41 AM
👩🔬👨💻 Postdoc recruitment! 👨🔬👩💻
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Reposted by Jan Mašek
hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!
September 15, 2025 at 5:26 PM
hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!
Reposted by Jan Mašek
🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...
Scientific bedlam at the world’s weirdest and wildest research conference
Woodstock Bio2 + Night Science aimed to encourage collaborations through creativity. The walk-on music for presentations was fun, too.
www.nature.com
July 31, 2025 at 4:22 AM
🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...
Reposted by Jan Mašek
Read all Elements in The Philosophy of Biology series for FREE during the ISHPSSB conference 20 - 25 July. You can find all of these Elements free to download and read here: cup.org/4kEgivL
Philosophy of Biology
Welcome to Cambridge Core
cup.org
July 20, 2025 at 5:16 PM
Read all Elements in The Philosophy of Biology series for FREE during the ISHPSSB conference 20 - 25 July. You can find all of these Elements free to download and read here: cup.org/4kEgivL
Reposted by Jan Mašek
We should have the equivalent for PIs looking for students and/or postdocs
go.bsky.app/8zZNEGV
Great resource to connect early career folks with more senior scientists looking to hire postdocs! 🧪
Great resource to connect early career folks with more senior scientists looking to hire postdocs! 🧪
July 17, 2025 at 12:40 PM
We should have the equivalent for PIs looking for students and/or postdocs
Reposted by Jan Mašek
Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment.
tinyurl.com/mr3he6bx
tinyurl.com/mr3he6bx
FDA-NIH Workshop: Reducing Animal Testing
The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.
tinyurl.com
July 11, 2025 at 5:22 PM
Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment.
tinyurl.com/mr3he6bx
tinyurl.com/mr3he6bx
Reposted by Jan Mašek
Reposted by Jan Mašek
Read this piece. It gives a great impression of #TCTeAC WoodstockBio2 & Night Science from one of the #Instigators. This is the next best thing to being there... I like the expression #BohemianFixers. Many thanks to them! Děkujeme.
thenode.biologists.com/from-posters...
thenode.biologists.com/from-posters...
From Posters to Parades: Inside Woodstock.Bio² & Night Science Conference - the Node
A fever dream of science and spirit wrapped in the forests of Bohemia. Here’s an escalating list — starting with the standard (though nothing was standard
thenode.biologists.com
June 26, 2025 at 12:13 PM
Read this piece. It gives a great impression of #TCTeAC WoodstockBio2 & Night Science from one of the #Instigators. This is the next best thing to being there... I like the expression #BohemianFixers. Many thanks to them! Děkujeme.
thenode.biologists.com/from-posters...
thenode.biologists.com/from-posters...
Reposted by Jan Mašek
The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil
June 26, 2025 at 8:15 AM
The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil
Reposted by Jan Mašek
I am heartbroken about the loss of many labs at the Weizmann Institute yesterday in the missile attack. Dear scientists there: please know that you are not alone. Like many many others, I support you and am standing by to help you in any way I can.
June 16, 2025 at 12:19 PM
I am heartbroken about the loss of many labs at the Weizmann Institute yesterday in the missile attack. Dear scientists there: please know that you are not alone. Like many many others, I support you and am standing by to help you in any way I can.
Reposted by Jan Mašek
This might be useful for the #TCTeAC participants 🇨🇿, 🙏 @svobodalab.bsky.social @odedrechavi.bsky.social @itaiyanai.bsky.social go.bsky.app/DPH6r8o
June 13, 2025 at 1:24 PM
This might be useful for the #TCTeAC participants 🇨🇿, 🙏 @svobodalab.bsky.social @odedrechavi.bsky.social @itaiyanai.bsky.social go.bsky.app/DPH6r8o
Super nice talk by @jesseveenvliet.bsky.social on how the environment restricts the possible courses of embryonic development 🤓 #TCTeAC
June 11, 2025 at 10:18 AM
Super nice talk by @jesseveenvliet.bsky.social on how the environment restricts the possible courses of embryonic development 🤓 #TCTeAC
@honzadobes87.bsky.social nailing his talk at WoB2 conference #TCTeAC
June 11, 2025 at 8:10 AM
@honzadobes87.bsky.social nailing his talk at WoB2 conference #TCTeAC
Reposted by Jan Mašek
📣Check out our recent review (written with Martina Huranova lab) on converging mechanisms controlling #cilia #dynamics during #cell #cycle, #cell #signaling, and cross-talk of ciliary modules.
rdcu.be/epVDc
rdcu.be/epVDc
Cilia at the crossroad: convergence of regulatory mechanisms to govern cilia dynamics during cell signaling and the cell cycle
rdcu.be
June 10, 2025 at 6:35 AM
📣Check out our recent review (written with Martina Huranova lab) on converging mechanisms controlling #cilia #dynamics during #cell #cycle, #cell #signaling, and cross-talk of ciliary modules.
rdcu.be/epVDc
rdcu.be/epVDc
Reposted by Jan Mašek
English-speaking colleagues welcome!
Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎
If you’re planning to join us, let us please know via the link above 🙏
Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎
If you’re planning to join us, let us please know via the link above 🙏
May 18, 2025 at 10:35 AM
English-speaking colleagues welcome!
Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎
If you’re planning to join us, let us please know via the link above 🙏
Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎
If you’re planning to join us, let us please know via the link above 🙏
Reposted by Jan Mašek
Let's talk about a party—where drugs don't hit the dance floor but finely tune #EpithelialMechanics by hitting actomyosin cortex! 🧬💊
Here's our guide to doing drugs 🧵
Here's our guide to doing drugs 🧵
May 18, 2025 at 2:19 AM
Let's talk about a party—where drugs don't hit the dance floor but finely tune #EpithelialMechanics by hitting actomyosin cortex! 🧬💊
Here's our guide to doing drugs 🧵
Here's our guide to doing drugs 🧵
Reposted by Jan Mašek
We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
May 1, 2025 at 7:32 AM
We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
Reposted by Jan Mašek
We had previously shown that TBX3 and #WNT cooperate in limb #DevBio
We now have a shocking finding, just published in @pnas.org
TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC)
www.pnas.org/doi/epub/10....
We now have a shocking finding, just published in @pnas.org
TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC)
www.pnas.org/doi/epub/10....
The developmental factor TBX3 engages with the Wnt/β-catenin transcriptional complex in colorectal cancer to regulate metastasis genes
www.pnas.org
May 12, 2025 at 7:33 AM
We had previously shown that TBX3 and #WNT cooperate in limb #DevBio
We now have a shocking finding, just published in @pnas.org
TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC)
www.pnas.org/doi/epub/10....
We now have a shocking finding, just published in @pnas.org
TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC)
www.pnas.org/doi/epub/10....
Reposted by Jan Mašek
🌟 #PI_Forum Brno #5: Academic Leadership: The Big Picture is ahead!
How does one lead a team vs. an institution?
Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond.
🗓️ 13 May 2025
📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...
How does one lead a team vs. an institution?
Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond.
🗓️ 13 May 2025
📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...
April 30, 2025 at 8:34 AM
🌟 #PI_Forum Brno #5: Academic Leadership: The Big Picture is ahead!
How does one lead a team vs. an institution?
Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond.
🗓️ 13 May 2025
📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...
How does one lead a team vs. an institution?
Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond.
🗓️ 13 May 2025
📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...
Reposted by Jan Mašek
Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social.
I'm so excited about this!
www.biorxiv.org/content/10.1...
I'm so excited about this!
www.biorxiv.org/content/10.1...
Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data
Single-cell omics methods promise to revolutionize our understanding of gene regulatory processes during cell differentiation, but analysis of such data continues to pose a major challenge. Apart from...
www.biorxiv.org
May 9, 2025 at 10:49 AM
Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social.
I'm so excited about this!
www.biorxiv.org/content/10.1...
I'm so excited about this!
www.biorxiv.org/content/10.1...
Reposted by Jan Mašek
🤝 IOCB Prague is hiring – we are looking for an outstanding Junior Group Leader in Biosciences to join our vibrant scientific community.
See more ► www.uochb.cz/en/open-posi... ⤵️
#openposition #iocbprague #iocb #researchjobs #biosciences
See more ► www.uochb.cz/en/open-posi... ⤵️
#openposition #iocbprague #iocb #researchjobs #biosciences
May 6, 2025 at 7:09 PM
🤝 IOCB Prague is hiring – we are looking for an outstanding Junior Group Leader in Biosciences to join our vibrant scientific community.
See more ► www.uochb.cz/en/open-posi... ⤵️
#openposition #iocbprague #iocb #researchjobs #biosciences
See more ► www.uochb.cz/en/open-posi... ⤵️
#openposition #iocbprague #iocb #researchjobs #biosciences
Reposted by Jan Mašek
📢 Tři osobnosti, tři příběhy, tři vědecké světy - takové bylo předávání druhého ročníku letošní Ceny Czexpats In Science!
Celý článek již na našem webu ⏬ czexpats.org/clanek/tri-o...
Celý článek již na našem webu ⏬ czexpats.org/clanek/tri-o...
Tři osobnosti, tři příběhy, tři vědecké světy. Takové bylo předávání druhého ročníku Ceny Czexpats in Science. - Czexpats in Science
Cenu Czexpats in Science pro mladé vědce a vědkyně působící v zahraničí letos získali tři výrazné osobnosti – bioinformatička Monika Čechová, právník Jakub Drápal a expert na umělou inteligenci Stanis...
czexpats.org
May 7, 2025 at 4:10 PM
📢 Tři osobnosti, tři příběhy, tři vědecké světy - takové bylo předávání druhého ročníku letošní Ceny Czexpats In Science!
Celý článek již na našem webu ⏬ czexpats.org/clanek/tri-o...
Celý článek již na našem webu ⏬ czexpats.org/clanek/tri-o...
Honored to receive these t-shirts, learning the powerful story of Roberta Smith from the Alagille Syndrome Alliance behind them. 💛 www.linkedin.com/in/roberta-s...
May 2, 2025 at 12:24 PM
Honored to receive these t-shirts, learning the powerful story of Roberta Smith from the Alagille Syndrome Alliance behind them. 💛 www.linkedin.com/in/roberta-s...