@markgerstein.bsky.social
Posting my talk tomorrow at the Computational Molecular Sciences & Engineering (CMSE) Symposium @Yale lectures.gersteinlab.org/summary/Enha... Lots of new slides on the discard-and-restart approach for enhanced structural sampling
November 10, 2025 at 4:40 AM
Posting my talk tomorrow at the Computational Molecular Sciences & Engineering (CMSE) Symposium @Yale lectures.gersteinlab.org/summary/Enha... Lots of new slides on the discard-and-restart approach for enhanced structural sampling
Posting my talk today for the AI in Health Series lectures.gersteinlab.org/summary/AI-M... Goes over an evolution of computational methods for biomedicine: Classical, DL & Quantum.
November 5, 2025 at 6:20 PM
Posting my talk today for the AI in Health Series lectures.gersteinlab.org/summary/AI-M... Goes over an evolution of computational methods for biomedicine: Classical, DL & Quantum.
Posting my talk tomorrow on Biomed AI @mila-quebec.bsky.social lectures.gersteinlab.org/summary/Biom...
Some new slides from Yunzhe Jiang on ENTEx & variant impact prediction and W Lee on ensembling ML models for drug screening
Some new slides from Yunzhe Jiang on ENTEx & variant impact prediction and W Lee on ensembling ML models for drug screening
October 16, 2025 at 3:06 AM
Posting my talk tomorrow on Biomed AI @mila-quebec.bsky.social lectures.gersteinlab.org/summary/Biom...
Some new slides from Yunzhe Jiang on ENTEx & variant impact prediction and W Lee on ensembling ML models for drug screening
Some new slides from Yunzhe Jiang on ENTEx & variant impact prediction and W Lee on ensembling ML models for drug screening
Posting my talk tomorrow on AI in Biomedicine at
Einstein Med (hosted by @zhengdy.bsky.social)
lectures.gersteinlab.org/summary/AI-t... Using AI for brain genomics & thinking about how it can do this research autonomously. Lots of new slides on AI coding & risks
Einstein Med (hosted by @zhengdy.bsky.social)
lectures.gersteinlab.org/summary/AI-t... Using AI for brain genomics & thinking about how it can do this research autonomously. Lots of new slides on AI coding & risks
October 9, 2025 at 2:41 AM
Posting my talk tomorrow on AI in Biomedicine at
Einstein Med (hosted by @zhengdy.bsky.social)
lectures.gersteinlab.org/summary/AI-t... Using AI for brain genomics & thinking about how it can do this research autonomously. Lots of new slides on AI coding & risks
Einstein Med (hosted by @zhengdy.bsky.social)
lectures.gersteinlab.org/summary/AI-t... Using AI for brain genomics & thinking about how it can do this research autonomously. Lots of new slides on AI coding & risks
Reposted
🧵The Nobel Prize in Physics today went to John Clarke (UK), Michel Devoret (France), & John Martinis (USA) today for work conducted in Clarke's UC Berkeley lab in the mid 80s showing that alternation of a quantum state could proceed from one side to the other of a device you can see with your eye.
October 7, 2025 at 3:16 PM
🧵The Nobel Prize in Physics today went to John Clarke (UK), Michel Devoret (France), & John Martinis (USA) today for work conducted in Clarke's UC Berkeley lab in the mid 80s showing that alternation of a quantum state could proceed from one side to the other of a device you can see with your eye.
Reposted
📚 Yale students have returned to campus, so time for a roster meeting!
We again made our Nobel Prize predictions (given how accurate we were last year 😉)
🥇Our top prediction is Habener & Knudsen (GLP-1) with 28.5% of the vote!
🥈 In second is Rothberg & David Klenerman (NGS)
We again made our Nobel Prize predictions (given how accurate we were last year 😉)
🥇Our top prediction is Habener & Knudsen (GLP-1) with 28.5% of the vote!
🥈 In second is Rothberg & David Klenerman (NGS)
September 22, 2025 at 7:01 PM
📚 Yale students have returned to campus, so time for a roster meeting!
We again made our Nobel Prize predictions (given how accurate we were last year 😉)
🥇Our top prediction is Habener & Knudsen (GLP-1) with 28.5% of the vote!
🥈 In second is Rothberg & David Klenerman (NGS)
We again made our Nobel Prize predictions (given how accurate we were last year 😉)
🥇Our top prediction is Habener & Knudsen (GLP-1) with 28.5% of the vote!
🥈 In second is Rothberg & David Klenerman (NGS)
Did my annual triathlon today in Madison. Good swim. Steady bike. Walk-skip-walk to the finish line. Made it! And, unlike last year, did an extensive stretch afterwards & drove myself home. Before & after race pics. (More at flickr.com/photos/mbgmb...)
September 6, 2025 at 10:22 PM
Did my annual triathlon today in Madison. Good swim. Steady bike. Walk-skip-walk to the finish line. Made it! And, unlike last year, did an extensive stretch afterwards & drove myself home. Before & after race pics. (More at flickr.com/photos/mbgmb...)
Reposted
Curious how your favorite gene changes when and how during a biological process?
Want to dive into the kinetics of chromatin + gene expression?
Meet chronODE, our new tool to model multi-omic time-series with logistic equations + ML!
doi.org/10.1038/s414...
Want to dive into the kinetics of chromatin + gene expression?
Meet chronODE, our new tool to model multi-omic time-series with logistic equations + ML!
doi.org/10.1038/s414...
The chronODE framework for modelling multi-omic time series with ordinary differential equations and machine learning - Nature Communications
Here, the authors use a simple equation to study how genes and their regulators switch on/off over time, across the whole genome in tissues and cells. Most changes are gradual, but some genes switch q...
doi.org
August 25, 2025 at 3:37 PM
Curious how your favorite gene changes when and how during a biological process?
Want to dive into the kinetics of chromatin + gene expression?
Meet chronODE, our new tool to model multi-omic time-series with logistic equations + ML!
doi.org/10.1038/s414...
Want to dive into the kinetics of chromatin + gene expression?
Meet chronODE, our new tool to model multi-omic time-series with logistic equations + ML!
doi.org/10.1038/s414...
Posting my talk on AI & Brain Disorders at Princeton CHDI on Tuesday lectures.gersteinlab.org/summary/Ext-... Lots of new slides on drug repurposing and predicting age from histology images
August 18, 2025 at 4:48 AM
Posting my talk on AI & Brain Disorders at Princeton CHDI on Tuesday lectures.gersteinlab.org/summary/Ext-... Lots of new slides on drug repurposing and predicting age from histology images
Thoughts on Pearl's Book of Why blog.gerstein.info/2025/08/thou... Lots of Good Intuition on Bayesian Networks, Sometimes with Strong Opinions
August 2, 2025 at 11:21 PM
Thoughts on Pearl's Book of Why blog.gerstein.info/2025/08/thou... Lots of Good Intuition on Bayesian Networks, Sometimes with Strong Opinions
Reposted
"The microplastic (MP) 1–10 μm exposure estimates are 100-fold higher than previous estimates that were extrapolated from larger MP sizes, and suggest that the health impacts of MP inhalation may be more substantial than we realize."
journals.plos.org/plosone/arti...
journals.plos.org/plosone/arti...
Human exposure to PM10 microplastics in indoor air
The ubiquitous presence of airborne microplastics (MPs) in different indoor environments prompts serious concerns about the degree to which we inhale these particles and their potential impact on huma...
journals.plos.org
July 30, 2025 at 6:18 PM
"The microplastic (MP) 1–10 μm exposure estimates are 100-fold higher than previous estimates that were extrapolated from larger MP sizes, and suggest that the health impacts of MP inhalation may be more substantial than we realize."
journals.plos.org/plosone/arti...
journals.plos.org/plosone/arti...
Posting my talk tomorrow at @emblebi.bsky.social (for the @ensembl.bsky.social group) lectures.gersteinlab.org/summary/Expl... AI Approaches for Understanding Brain Disorders: Exploring Intermediate Endophenotypes connecting Genotype to Diseases
July 30, 2025 at 7:02 PM
Posting my talk tomorrow at @emblebi.bsky.social (for the @ensembl.bsky.social group) lectures.gersteinlab.org/summary/Expl... AI Approaches for Understanding Brain Disorders: Exploring Intermediate Endophenotypes connecting Genotype to Diseases
Posting my talk tomorrow at @geneticscam.bsky.social on AI for Brain Disorders lectures.gersteinlab.org/summary/Mode... Lots of new slides on characterizing brain developmental time series with sigmoids
July 28, 2025 at 10:17 PM
Posting my talk tomorrow at @geneticscam.bsky.social on AI for Brain Disorders lectures.gersteinlab.org/summary/Mode... Lots of new slides on characterizing brain developmental time series with sigmoids
Posting my talk on Mon. on Cancer Genomics at the Institut Curie lectures.gersteinlab.org/summary/Char... Lots of new slides on using LLMs for "tumor boards" & for generating genomics workflows
July 19, 2025 at 4:55 PM
Posting my talk on Mon. on Cancer Genomics at the Institut Curie lectures.gersteinlab.org/summary/Char... Lots of new slides on using LLMs for "tumor boards" & for generating genomics workflows
Posting my talk tomorrow at the AI4Chemistry Summit at NYU lectures.gersteinlab.org/summary/AI-f... Lots of new slides on computing small molecule Hamiltonians & predicting macromolecular misfolding
June 26, 2025 at 3:15 AM
Posting my talk tomorrow at the AI4Chemistry Summit at NYU lectures.gersteinlab.org/summary/AI-f... Lots of new slides on computing small molecule Hamiltonians & predicting macromolecular misfolding
Posting my talk tomorrow at the SCORCH consortium meeting lectures.gersteinlab.org/summary/Chro... Tools for brain single-cell analysis: ChronODE for series data and ASTRO for spatial data.
June 23, 2025 at 2:12 AM
Posting my talk tomorrow at the SCORCH consortium meeting lectures.gersteinlab.org/summary/Chro... Tools for brain single-cell analysis: ChronODE for series data and ASTRO for spatial data.
Reposted
Join us next week for MB&B's Computational Biophysics & Biochemistry Symposium on 6/17 in Bass 305!
June 9, 2025 at 2:53 PM
Join us next week for MB&B's Computational Biophysics & Biochemistry Symposium on 6/17 in Bass 305!
Posting my talk tomorrow for the IMPACT-MH Consortium lectures.gersteinlab.org/summary/Digi... Digital Phenotyping from Wearables Using AI. Some new slides on using wearables to predict exercise lapses
June 9, 2025 at 1:58 AM
Posting my talk tomorrow for the IMPACT-MH Consortium lectures.gersteinlab.org/summary/Digi... Digital Phenotyping from Wearables Using AI. Some new slides on using wearables to predict exercise lapses
School's out for the summer, & I've finally got around to cleaning up the website for my class on biomedical data science (gersteinlab.org/courses/452)
I've been teaching this course for >25 years. This year, we've posted lots of new lecture videos.
I've been teaching this course for >25 years. This year, we've posted lots of new lecture videos.
June 7, 2025 at 2:05 AM
School's out for the summer, & I've finally got around to cleaning up the website for my class on biomedical data science (gersteinlab.org/courses/452)
I've been teaching this course for >25 years. This year, we've posted lots of new lecture videos.
I've been teaching this course for >25 years. This year, we've posted lots of new lecture videos.
Reposted
📣 200+ Innovators Presenting at the 2025 Yale Innovation Summit 📣
Meet the founders who will compete for $300k in prizes during 6 live pitch sessions, interactive ePoster presentations, and virtual showcases at #YaleInnovation2025
👉 bit.ly/3GKJ0Mk
Meet the founders who will compete for $300k in prizes during 6 live pitch sessions, interactive ePoster presentations, and virtual showcases at #YaleInnovation2025
👉 bit.ly/3GKJ0Mk
May 8, 2025 at 8:11 PM
📣 200+ Innovators Presenting at the 2025 Yale Innovation Summit 📣
Meet the founders who will compete for $300k in prizes during 6 live pitch sessions, interactive ePoster presentations, and virtual showcases at #YaleInnovation2025
👉 bit.ly/3GKJ0Mk
Meet the founders who will compete for $300k in prizes during 6 live pitch sessions, interactive ePoster presentations, and virtual showcases at #YaleInnovation2025
👉 bit.ly/3GKJ0Mk
Liked the visual effect of @newyorker.com's recent "Double Cover"
May 27, 2025 at 3:04 AM
Liked the visual effect of @newyorker.com's recent "Double Cover"
Posting my talk tomorrow at the @broadinstitute.org's Stanley Center lectures.gersteinlab.org/summary/Expl... Exploring Intermediate Endophenotypes connecting Genotype to Diseases
May 14, 2025 at 11:35 PM
Posting my talk tomorrow at the @broadinstitute.org's Stanley Center lectures.gersteinlab.org/summary/Expl... Exploring Intermediate Endophenotypes connecting Genotype to Diseases
Reposted
1/4 🚀 New #ICLR2025 SPOTLIGHT ALERT
Gerstein Lab presents “Enhancing the Scalability & Applicability of Kohn-Sham Hamiltonians”—led by YunyangLI & Z Xia & L Huang & J Zhang & @markgerstein.bsky.social . Joint work with @msftresearch.bsky.social .
Gerstein Lab presents “Enhancing the Scalability & Applicability of Kohn-Sham Hamiltonians”—led by YunyangLI & Z Xia & L Huang & J Zhang & @markgerstein.bsky.social . Joint work with @msftresearch.bsky.social .
May 5, 2025 at 5:16 PM
1/4 🚀 New #ICLR2025 SPOTLIGHT ALERT
Gerstein Lab presents “Enhancing the Scalability & Applicability of Kohn-Sham Hamiltonians”—led by YunyangLI & Z Xia & L Huang & J Zhang & @markgerstein.bsky.social . Joint work with @msftresearch.bsky.social .
Gerstein Lab presents “Enhancing the Scalability & Applicability of Kohn-Sham Hamiltonians”—led by YunyangLI & Z Xia & L Huang & J Zhang & @markgerstein.bsky.social . Joint work with @msftresearch.bsky.social .
Posting my talk today at
the @ucirvine.bsky.social center for Neural Circuit Mapping lectures.gersteinlab.org/summary/SCZ-... . Lots of slides on using AI approaches for Schizophrenia, Alzheimer's & ADHD, including some new ones on analyzing AD imaging.
the @ucirvine.bsky.social center for Neural Circuit Mapping lectures.gersteinlab.org/summary/SCZ-... . Lots of slides on using AI approaches for Schizophrenia, Alzheimer's & ADHD, including some new ones on analyzing AD imaging.
May 6, 2025 at 3:03 PM
Posting my talk today at
the @ucirvine.bsky.social center for Neural Circuit Mapping lectures.gersteinlab.org/summary/SCZ-... . Lots of slides on using AI approaches for Schizophrenia, Alzheimer's & ADHD, including some new ones on analyzing AD imaging.
the @ucirvine.bsky.social center for Neural Circuit Mapping lectures.gersteinlab.org/summary/SCZ-... . Lots of slides on using AI approaches for Schizophrenia, Alzheimer's & ADHD, including some new ones on analyzing AD imaging.