Manuela Aguirre-Botero
banner
maguirreb.bsky.social
Manuela Aguirre-Botero
@maguirreb.bsky.social
PhD | Parasitologist 📍in 🇫🇷 | Malaria and Immunity Unit | 🇨🇴
Pinned
Curious about how antibodies can target Plasmodium sporozoites?

Very happy to see this review out, it means a lot to me to finish my PhD research topic with a nice overview of what is known about how anti-CSP Abs neutralize the parasite in the mammalian host.
Reposted by Manuela Aguirre-Botero
🥳🎉Our brand-new review on species-specific differences in interferon response effectors and the resulting barriers to interspecies transmission of viruses is out, go read it!🥳🎉
Viral interferon antagonism shapes host tropism
Outbreaks of zoonotic viruses in human populations highlight the need to understand the molecular factors that influence viral host tropism and interspecies transmission. A virus’s host range is deter...
journals.plos.org
October 8, 2025 at 7:40 AM
Curious about how antibodies can target Plasmodium sporozoites?

Very happy to see this review out, it means a lot to me to finish my PhD research topic with a nice overview of what is known about how anti-CSP Abs neutralize the parasite in the mammalian host.
September 2, 2025 at 10:06 PM
Reposted by Manuela Aguirre-Botero
New Review alert! Tissue-dependent protection mechanisms of #antibodies targeting #Plasmodium #sporozoites, authored by @maguirreb.bsky.social & Rogerio Amino. #malaria #circumsporozoiteprotein #CSP @pasteur.fr@upcite.bsky.social

authors.elsevier.com/a/1lhKa5Eb1x...
August 31, 2025 at 8:37 AM
Reposted by Manuela Aguirre-Botero
🦟 Today is #worldmosquitoday! It's a good opportunity to show what it takes to rear Anopheles mosquitos for our #malaria research.
First, let's look at how many mosquitos are bred in the Levashina Lab each year.
Check out the following posts to learn what it takes to keep them happy! (1/4) 👇
August 20, 2025 at 12:54 PM
Reposted by Manuela Aguirre-Botero
🔬 This polarized light microscopy image shows Schistosoma mansoni, a parasite that causes schistosomiasis. #WorldHealthDay 🌍 #MicroscopyMonday

📲 Read more about the MBL's research on S. mansoni: bit.ly/3R90jbQ

📷: MBL Biology of Parasitism students and Michael Shribak
April 7, 2025 at 9:29 PM
Reposted by Manuela Aguirre-Botero
Curious about the Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody? doi.org/10.7554/eLif...
Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody
A late-neutralizing monoclonal antibody targeting the major surface antigen of plasmodial sporozoites impairs the fitness of intracellular parasites, offering mechanistic insights to guide the develop...
doi.org
February 15, 2025 at 2:06 PM
Curious about the Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody? doi.org/10.7554/eLif...
Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody
A late-neutralizing monoclonal antibody targeting the major surface antigen of plasmodial sporozoites impairs the fitness of intracellular parasites, offering mechanistic insights to guide the develop...
doi.org
February 15, 2025 at 2:06 PM
Reposted by Manuela Aguirre-Botero
🧬 Excited to share our latest work, MUSET 🌭, a new tool for creating abundance unitig matrices from sequencing data. It was published yesterday in Oxford Bioinformatics if you want to have a look👀 :

academic.oup.com/bioinformati...

Let's break it down:
MUSET: Set of utilities for constructing abundance unitig matrices from sequencing data
AbstractSummary. MUSET is a novel set of utilities designed to efficiently construct abundance unitig matrices from sequencing data. Unitig matrices extend
academic.oup.com
February 4, 2025 at 2:47 PM
Still in the process of realizing that I just finished my PhD! As my first post I would like to thank again
the most amazing boss: Rogerio Amino. Also an special thanks to all the people who were part of this journey
Institut Pasteur Education | Université Paris Cité | #PPUprogram
December 3, 2024 at 9:28 PM