Lydia O'Sullivan
@lydiaosullivan.bsky.social
Radiotherapy, oncology, clinical trials methodology, evidence synthesis, HTA, outdoors, beaches, dogs.
Research Associate at HRB-TMRN
Views my own.
Research Associate at HRB-TMRN
Views my own.
Reposted by Lydia O'Sullivan
Recruitment to cancer #ClinicalTrials is often highly selective, and some people face barriers to participation.
To prevent these issues from limiting our progress against the disease, we're working to bridge the gap between clinical trials and real-world practice ⬇️
www.icr.ac.uk/research-and...
To prevent these issues from limiting our progress against the disease, we're working to bridge the gap between clinical trials and real-world practice ⬇️
www.icr.ac.uk/research-and...
August 14, 2025 at 1:36 PM
Recruitment to cancer #ClinicalTrials is often highly selective, and some people face barriers to participation.
To prevent these issues from limiting our progress against the disease, we're working to bridge the gap between clinical trials and real-world practice ⬇️
www.icr.ac.uk/research-and...
To prevent these issues from limiting our progress against the disease, we're working to bridge the gap between clinical trials and real-world practice ⬇️
www.icr.ac.uk/research-and...
Reposted by Lydia O'Sullivan
There has been a lot of debate recently about the promise of real world data - the routine (observational) data collected on patients eg treatments received, clinical outcomes etc – for estimating treatment effects. But can they deliver? 1/9
#MethodologyMonday #123
#MethodologyMonday #123
August 18, 2025 at 6:35 AM
There has been a lot of debate recently about the promise of real world data - the routine (observational) data collected on patients eg treatments received, clinical outcomes etc – for estimating treatment effects. But can they deliver? 1/9
#MethodologyMonday #123
#MethodologyMonday #123
Reposted by Lydia O'Sullivan
Reposted by Lydia O'Sullivan
The updated SPIRIT 2025 statement enhances randomized trial protocols, adding clarity and transparency for better research practices.
by Chan AW, Boutron I (...) Hróbjartsson A et 36 al. in JAMA #MedSky
👉 get more here
📖 read the article:
by Chan AW, Boutron I (...) Hróbjartsson A et 36 al. in JAMA #MedSky
👉 get more here
📖 read the article:
SPIRIT 2025 Statement
This Special Communication introduces the updated Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2025 statement, which includes substantive and structural changes to incorporate new evidence and emerging perspectives.
jamanetwork.com
May 7, 2025 at 6:40 PM
Reposted by Lydia O'Sullivan
Scoping reviews & their role in identifying research priorities
H. Khalil, R. Jia, E.B. Moraes, Z. Munn, L. Alexander, MDJ Peters, A. Asran, C.M. Godfrey, @andreatricco.bsky.social, @daniellepollock.bsky.social, C. Evans
www.jclinepi.com/article/S089...
H. Khalil, R. Jia, E.B. Moraes, Z. Munn, L. Alexander, MDJ Peters, A. Asran, C.M. Godfrey, @andreatricco.bsky.social, @daniellepollock.bsky.social, C. Evans
www.jclinepi.com/article/S089...
Scoping reviews and their role in identifying research priorities
Scoping reviews have been identified as appropriate methodologies to contribute to
our knowledge. The objective of this review is to summarise how scoping reviews can
be used to identify research prio...
www.jclinepi.com
February 10, 2025 at 9:07 PM
Scoping reviews & their role in identifying research priorities
H. Khalil, R. Jia, E.B. Moraes, Z. Munn, L. Alexander, MDJ Peters, A. Asran, C.M. Godfrey, @andreatricco.bsky.social, @daniellepollock.bsky.social, C. Evans
www.jclinepi.com/article/S089...
H. Khalil, R. Jia, E.B. Moraes, Z. Munn, L. Alexander, MDJ Peters, A. Asran, C.M. Godfrey, @andreatricco.bsky.social, @daniellepollock.bsky.social, C. Evans
www.jclinepi.com/article/S089...
Reposted by Lydia O'Sullivan
That sounds like a perfect way to kick off the day! A cup of coffee always sets the right tone. ☕😊
#nicedogs #coffeedogs #nicedaywithdog
#nicedogs #coffeedogs #nicedaywithdog
December 10, 2024 at 1:05 PM
That sounds like a perfect way to kick off the day! A cup of coffee always sets the right tone. ☕😊
#nicedogs #coffeedogs #nicedaywithdog
#nicedogs #coffeedogs #nicedaywithdog
Great talk Darren, thanks again. Lots of tips for us to action! @andrewdullea.bsky.social
Looking forward to chatting with colleagues from @hiqa.bsky.social today about data management and reproducible data analysis/reporting. Hopefully anyone who attends will know that I'm not being paid a dime and to set expectations accordingly 😜
Thanks @lydiaosullivan.bsky.social for the invite.
Thanks @lydiaosullivan.bsky.social for the invite.
January 21, 2025 at 2:24 PM
Great talk Darren, thanks again. Lots of tips for us to action! @andrewdullea.bsky.social
Reposted by Lydia O'Sullivan
Hello Bluesky 👋 #ThePeoplesReview is a citizen science project inviting the public to get involved in a systematic review about health!
Check out this video for more info about what The People’s Review is all about - youtu.be/4OoIjJY0tbE
Check out this video for more info about what The People’s Review is all about - youtu.be/4OoIjJY0tbE
What is The People's Review?
YouTube video by The People's Review
youtu.be
November 18, 2024 at 1:16 PM
Hello Bluesky 👋 #ThePeoplesReview is a citizen science project inviting the public to get involved in a systematic review about health!
Check out this video for more info about what The People’s Review is all about - youtu.be/4OoIjJY0tbE
Check out this video for more info about what The People’s Review is all about - youtu.be/4OoIjJY0tbE
Reposted by Lydia O'Sullivan
Yet more evidence that including a librarian in an evidence synthesis project improves quality and reproducibility pmc.ncbi.nlm.nih.gov/articles/PMC... #medlibs #systematicreviews
Effect of librarian collaboration on otolaryngology systematic review and meta-analysis quality
To determine if librarian collaboration was associated with improved database search quality, search reproducibility, and systematic review reporting in otolaryngology systematic reviews and meta-anal...
pmc.ncbi.nlm.nih.gov
November 13, 2024 at 8:42 AM
Yet more evidence that including a librarian in an evidence synthesis project improves quality and reproducibility pmc.ncbi.nlm.nih.gov/articles/PMC... #medlibs #systematicreviews
Reposted by Lydia O'Sullivan
How should we describe randomisation to people when recruiting them to a trial? Simple little study, but useful for us all to think about how we do this - it is not just understanding that is important, we also need to consider the acceptability of the language we use.
rdcu.be/dZGg1
rdcu.be/dZGg1
Trial participants’ self-reported understanding of randomisation phrases in participation information leaflets can be high, but acceptability of some descriptions is low, especially those linked to ga...
rdcu.be
November 9, 2024 at 5:38 PM
How should we describe randomisation to people when recruiting them to a trial? Simple little study, but useful for us all to think about how we do this - it is not just understanding that is important, we also need to consider the acceptability of the language we use.
rdcu.be/dZGg1
rdcu.be/dZGg1
Reposted by Lydia O'Sullivan
Reflection paper on establishing efficacy based on single-arm trials submitted as pivotal evidence in a marketing authorisation.
www.ema.europa.eu/en/establish...
www.ema.europa.eu/en/establish...
Establishing efficacy based on single-arm trials submitted as pivotal evidence in a marketing authorisation | European Medicines Agency (EMA)
www.ema.europa.eu
September 20, 2024 at 8:11 AM
Reflection paper on establishing efficacy based on single-arm trials submitted as pivotal evidence in a marketing authorisation.
www.ema.europa.eu/en/establish...
www.ema.europa.eu/en/establish...
Reposted by Lydia O'Sullivan
Can I make another public service announcement, akin to the "don't ask your students to do systematic or scoping review but rather assign targeted activities that could help them perform one in the future?"
A thread!
A thread!
February 14, 2024 at 2:12 PM
Can I make another public service announcement, akin to the "don't ask your students to do systematic or scoping review but rather assign targeted activities that could help them perform one in the future?"
A thread!
A thread!