Wei Luo
@luoweicool.bsky.social
Assistant Professor of Microbiology and Immunology at Indiana University School of Medicine; Study germinal center and vaccines
A Human model of wound healing is accidentally generated 😢
September 9, 2025 at 8:20 PM
A Human model of wound healing is accidentally generated 😢
Thrilled to share that our manuscript is now published in Cell Reports! Our findings support a model in which BLIMP1 intrinsically regulates GC B cell fate through transcriptional control.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
BLIMP1 controls GC B cell expansion and exit through regulating cell cycle progression and key transcription factors BCL6 and IRF4
BLIMP1 is expressed in a subset of GCBCs. Conter et al. have shown that BLIMP1 intrinsically
regulates multiple key processes in GCBCs, including positive selection, cell-cycle
progression, isotype sw...
www.cell.com
July 14, 2025 at 5:23 PM
Thrilled to share that our manuscript is now published in Cell Reports! Our findings support a model in which BLIMP1 intrinsically regulates GC B cell fate through transcriptional control.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Wei Luo
BLIMP1 controls GC B cell expansion and exit through regulating cell cycle progression and key transcription factors BCL6 and IRF4 @cp-cellreports.bsky.social @luoweicool.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
July 13, 2025 at 4:17 PM
BLIMP1 controls GC B cell expansion and exit through regulating cell cycle progression and key transcription factors BCL6 and IRF4 @cp-cellreports.bsky.social @luoweicool.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Wei Luo
Reposted by Wei Luo
Omalizumab treats multi-food allergy better than oral immunotherapy
High rate of oral immunotherapy side effects in NIH trial explains superiority of omalizumab
www.jacionline.org/article/S009...
High rate of oral immunotherapy side effects in NIH trial explains superiority of omalizumab
www.jacionline.org/article/S009...
Treatment of Multi-Food Allergy with Omalizumab Compared to Omalizumab-Facilitated Multi-Allergen OIT
Both omalizumab and oral immunotherapy (OIT) are used to treat multi-food allergy,
but the two treatments have never been directly compared.
www.jacionline.org
March 3, 2025 at 2:30 AM
Omalizumab treats multi-food allergy better than oral immunotherapy
High rate of oral immunotherapy side effects in NIH trial explains superiority of omalizumab
www.jacionline.org/article/S009...
High rate of oral immunotherapy side effects in NIH trial explains superiority of omalizumab
www.jacionline.org/article/S009...
Reposted by Wei Luo
Asparagine drives immune evasion in bladder cancer via RIG-I stability and type I IFN signaling @jclinical-invest.bsky.social
www.jci.org/articles/vie...
www.jci.org/articles/vie...
February 20, 2025 at 2:55 AM
Asparagine drives immune evasion in bladder cancer via RIG-I stability and type I IFN signaling @jclinical-invest.bsky.social
www.jci.org/articles/vie...
www.jci.org/articles/vie...
Reposted by Wei Luo
#Measles is one of the leading causes of death among young children globally.
In 2023, an estimated 107 500 people died from measles, mostly children under age 5.
bit.ly/48SAtkf
In 2023, an estimated 107 500 people died from measles, mostly children under age 5.
bit.ly/48SAtkf
February 17, 2025 at 3:58 PM
#Measles is one of the leading causes of death among young children globally.
In 2023, an estimated 107 500 people died from measles, mostly children under age 5.
bit.ly/48SAtkf
In 2023, an estimated 107 500 people died from measles, mostly children under age 5.
bit.ly/48SAtkf
Reposted by Wei Luo
Ibex update!
Our single-cell BCR deep learning package just got a major overhaul!
✅ Now supports CDR3 & full CDR1/2/3 embeddings
✅ Human & mouse models available
✅ Trained on 2–10M unique sequences for high accuracy
Check it out! github.com/BorchLab/Ibex
Our single-cell BCR deep learning package just got a major overhaul!
✅ Now supports CDR3 & full CDR1/2/3 embeddings
✅ Human & mouse models available
✅ Trained on 2–10M unique sequences for high accuracy
Check it out! github.com/BorchLab/Ibex
GitHub - BorchLab/Ibex: Using BCR and expression for sequence embedding
Using BCR and expression for sequence embedding . Contribute to BorchLab/Ibex development by creating an account on GitHub.
github.com
February 15, 2025 at 11:43 AM
Ibex update!
Our single-cell BCR deep learning package just got a major overhaul!
✅ Now supports CDR3 & full CDR1/2/3 embeddings
✅ Human & mouse models available
✅ Trained on 2–10M unique sequences for high accuracy
Check it out! github.com/BorchLab/Ibex
Our single-cell BCR deep learning package just got a major overhaul!
✅ Now supports CDR3 & full CDR1/2/3 embeddings
✅ Human & mouse models available
✅ Trained on 2–10M unique sequences for high accuracy
Check it out! github.com/BorchLab/Ibex
Reposted by Wei Luo
Review @sciimmunology.bsky.social @tianyangmao.bsky.social
Linking vaccine adjuvant mechanisms of action to function
www.science.org/doi/10.1126/...
Linking vaccine adjuvant mechanisms of action to function
www.science.org/doi/10.1126/...
February 14, 2025 at 7:06 PM
Review @sciimmunology.bsky.social @tianyangmao.bsky.social
Linking vaccine adjuvant mechanisms of action to function
www.science.org/doi/10.1126/...
Linking vaccine adjuvant mechanisms of action to function
www.science.org/doi/10.1126/...
Reposted by Wei Luo
🚨 RFK Jr. Confirmed as HHS Secretary 🚨
We knew this was coming, but let’s be clear—we’re not backing down. LFV is ready to fight back against policies that threaten vaccine access, funding, & public health protections.
This is just the beginning. Now, more than ever, we need YOU.
1/2
We knew this was coming, but let’s be clear—we’re not backing down. LFV is ready to fight back against policies that threaten vaccine access, funding, & public health protections.
This is just the beginning. Now, more than ever, we need YOU.
1/2
February 13, 2025 at 10:20 PM
🚨 RFK Jr. Confirmed as HHS Secretary 🚨
We knew this was coming, but let’s be clear—we’re not backing down. LFV is ready to fight back against policies that threaten vaccine access, funding, & public health protections.
This is just the beginning. Now, more than ever, we need YOU.
1/2
We knew this was coming, but let’s be clear—we’re not backing down. LFV is ready to fight back against policies that threaten vaccine access, funding, & public health protections.
This is just the beginning. Now, more than ever, we need YOU.
1/2
Reposted by Wei Luo
Since RFK Jr just got confirmed today, I am taking this chance to share this wonderful @sciam.bsky.social piece on
The Staggering Success of Vaccines
www.scientificamerican.com/article/see-...
The Staggering Success of Vaccines
www.scientificamerican.com/article/see-...
See How Many Lives Vaccines Have Saved around the World
Vaccines are the first step toward health equity in many parts of the world
www.scientificamerican.com
February 13, 2025 at 6:07 PM
Since RFK Jr just got confirmed today, I am taking this chance to share this wonderful @sciam.bsky.social piece on
The Staggering Success of Vaccines
www.scientificamerican.com/article/see-...
The Staggering Success of Vaccines
www.scientificamerican.com/article/see-...
Reposted by Wei Luo
RFK Jr sought to block the vaccine & wanted a lot of you & your families to un-alive from COVID. Pass it on. www.nytimes.com/2025/01/17/h...
RFK Jr. Sought to Stop Covid Vaccinations 6 Months After Rollout
Robert F. Kennedy Jr. petitioned the F.D.A. to revoke authorization of the shots at a time when they were in high demand and considered life-saving.
www.nytimes.com
January 17, 2025 at 8:46 PM
RFK Jr sought to block the vaccine & wanted a lot of you & your families to un-alive from COVID. Pass it on. www.nytimes.com/2025/01/17/h...
Reposted by Wei Luo
This man is a profound danger. Every American should oppose his nomination.
January 17, 2025 at 10:02 PM
This man is a profound danger. Every American should oppose his nomination.
Reposted by Wei Luo
I've seen a child with tetanus, I've treated near fatal infections after chicken pox, and I've pronounced children dead from COVID whose parents refused to have them vaccinated.
We have lost our minds... and are about to lose so many of our precious children.
We have lost our minds... and are about to lose so many of our precious children.
December 13, 2024 at 1:38 PM
I've seen a child with tetanus, I've treated near fatal infections after chicken pox, and I've pronounced children dead from COVID whose parents refused to have them vaccinated.
We have lost our minds... and are about to lose so many of our precious children.
We have lost our minds... and are about to lose so many of our precious children.
Reposted by Wei Luo
Holy hell. RFK Jr’s team has been gunning to pull the polio vaccine. He really is trying to #MakeIronLungsGreatAgain.
Gift 🎁 link: www.nytimes.com/2024/12/13/h...
Gift 🎁 link: www.nytimes.com/2024/12/13/h...
December 13, 2024 at 7:29 PM
Holy hell. RFK Jr’s team has been gunning to pull the polio vaccine. He really is trying to #MakeIronLungsGreatAgain.
Gift 🎁 link: www.nytimes.com/2024/12/13/h...
Gift 🎁 link: www.nytimes.com/2024/12/13/h...
Reposted by Wei Luo
B CELL FUN FACT: Secrets of the GC #2
There are 300 billion B cells with total mass of 60g in the human body. That is 3 times the number of stars in the Milky Way! Naïve B cell express >10 million unique antibodies to protect us from this universe of possible antigens!
www.pnas.org/doi/10.1073/...
There are 300 billion B cells with total mass of 60g in the human body. That is 3 times the number of stars in the Milky Way! Naïve B cell express >10 million unique antibodies to protect us from this universe of possible antigens!
www.pnas.org/doi/10.1073/...
The total mass, number, and distribution of immune cells in the human body | PNAS
The immune system is a complex network of cells with critical functions in health
and disease. However, a comprehensive census of the cells compris...
www.pnas.org
December 9, 2024 at 11:22 AM
B CELL FUN FACT: Secrets of the GC #2
There are 300 billion B cells with total mass of 60g in the human body. That is 3 times the number of stars in the Milky Way! Naïve B cell express >10 million unique antibodies to protect us from this universe of possible antigens!
www.pnas.org/doi/10.1073/...
There are 300 billion B cells with total mass of 60g in the human body. That is 3 times the number of stars in the Milky Way! Naïve B cell express >10 million unique antibodies to protect us from this universe of possible antigens!
www.pnas.org/doi/10.1073/...
Another year! Enjoyed our department holiday party!
Had a great time at our department holiday party!
December 8, 2024 at 3:28 AM
Another year! Enjoyed our department holiday party!
Reposted by Wei Luo
Had a great time at our department holiday party!
December 8, 2024 at 3:25 AM
Had a great time at our department holiday party!
Reposted by Wei Luo
Vaccines against COVID-19 saved over 20 million lives in the first year alone, according to a study in Lancet Infectious Diseases. Anti vaxxers conveniently ignore such stats.
November 23, 2024 at 7:22 AM
Vaccines against COVID-19 saved over 20 million lives in the first year alone, according to a study in Lancet Infectious Diseases. Anti vaxxers conveniently ignore such stats.
Reposted by Wei Luo
We’re hiring! We’re looking for a senior member for our growing team. See as below 😄
indiana.peopleadmin.com/postings/26383
indiana.peopleadmin.com/postings/26383
Assistant Research Professor of Anatomy, Cell Biology & Physiology
The IU School of Medicine (IUSM) Department of Anatomy, Cell Biology & Physiology has a position open for a Assistant Research Professor. This is a faculty level position. The faculty will work with D...
indiana.peopleadmin.com
November 16, 2024 at 11:44 PM
We’re hiring! We’re looking for a senior member for our growing team. See as below 😄
indiana.peopleadmin.com/postings/26383
indiana.peopleadmin.com/postings/26383